Kristoffer Valerie

Publications

• Dynamic Inhibition of ATM Kinase Provides a Strategy for Glioblastoma Multiforme Radiosensitization and Growth Control
  Cell Cycle (Georgetown, Tex.). Mar, 2012  |   Pubmed ID: 22370485
• BRCA1-directed, Enhanced and Aberrant Homologous Recombination: Mechanism and Potential Treatment Strategies
  Cell Cycle (Georgetown, Tex.). Feb, 2012  |   Pubmed ID: 22306997
• Nanomaterial-mediated CNS Delivery of Diagnostic and Therapeutic Agents
  Advanced Drug Delivery Reviews. May, 2012  |   Pubmed ID: 22178615
• MRE11 and ATM AKTivate Pro-survival Signaling
  Cell Cycle (Georgetown, Tex.). Oct, 2011  |   Pubmed ID: 21946569
• DNA Double-strand Break - Induced Pro-survival Signaling
  Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Oct, 2011  |   Pubmed ID: 21726915
• Mutations in the BRCT Binding Site of BRCA1 Result in Hyper-recombination
  Aging. May, 2011  |   Pubmed ID: 21666281
• ATM-dependent ERK Signaling Via AKT in Response to DNA Double-strand Breaks
  Cell Cycle (Georgetown, Tex.). Feb, 2011  |   Pubmed ID: 21263216
• ATM-independent, High-fidelity Nonhomologous End Joining Predominates in Human Embryonic Stem Cells
  Aging. Sep, 2010  |   Pubmed ID: 20844317
• Dynamic Dependence on ATR and ATM for Double-strand Break Repair in Human Embryonic Stem Cells and Neural Descendants
  PloS One. 2010  |   Pubmed ID: 20368801
• Improved ATM Kinase Inhibitor KU-60019 Radiosensitizes Glioma Cells, Compromises Insulin, AKT and ERK Prosurvival Signaling, and Inhibits Migration and Invasion
  Molecular Cancer Therapeutics. Oct, 2009  |   Pubmed ID: 19808981
• Tyrosyl-DNA Phosphodiesterase and the Repair of 3'-phosphoglycolate-terminated DNA Double-strand Breaks
  DNA Repair. Aug, 2009  |   Pubmed ID: 19505854
• Requirement for XLF/Cernunnos in Alignment-based Gap Filling by DNA Polymerases Lambda and Mu for Nonhomologous End Joining in Human Whole-cell Extracts
  Nucleic Acids Research. Jul, 2009  |   Pubmed ID: 19420065
• Nuclear Factor I Isoforms Regulate Gene Expression During the Differentiation of Human Neural Progenitors to Astrocytes
  Stem Cells (Dayton, Ohio). May, 2009  |   Pubmed ID: 19418463
• Pro-survival AKT and ERK Signaling from EGFR and Mutant EGFRvIII Enhances DNA Double-strand Break Repair in Human Glioma Cells
  Cancer Biology & Therapy. Apr, 2009  |   Pubmed ID: 19252415
• In Vitro Complementation of Tdp1 Deficiency Indicates a Stabilized Enzyme-DNA Adduct from Tyrosyl but Not Glycolate Lesions As a Consequence of the SCAN1 Mutation
  DNA Repair. May, 2009  |   Pubmed ID: 19211312
• Cloning and Characterization of SARI (suppressor of AP-1, Regulated by IFN)
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008  |   Pubmed ID: 19074269
• Coordinate 5' and 3' Endonucleolytic Trimming of Terminally Blocked Blunt DNA Double-strand Break Ends by Artemis Nuclease and DNA-dependent Protein Kinase
  Nucleic Acids Research. Jun, 2008  |   Pubmed ID: 18440975
• Novel Mode for Neutrophil Protease Cathepsin G-mediated Signaling: Membrane Shedding of Epidermal Growth Factor is Required for Cardiomyocyte Anoikis
  Circulation Research. Jan, 2008  |   Pubmed ID: 17975113
• Progression Elevated Gene-3 Promoter (PEG-Prom) Confers Cancer Cell Selectivity to Human Polynucleotide Phosphorylase (hPNPase(old-35))-mediated Growth Suppression
  Journal of Cellular Physiology. May, 2008  |   Pubmed ID: 17960560
• Phosphorylation in the Serine/threonine 2609-2647 Cluster Promotes but is Not Essential for DNA-dependent Protein Kinase-mediated Nonhomologous End Joining in Human Whole-cell Extracts
  Nucleic Acids Research. 2007  |   Pubmed ID: 17526517
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  Molecular Cancer Therapeutics. Mar, 2007  |   Pubmed ID: 17363476
• Extracellular Signal-related Kinase Positively Regulates Ataxia Telangiectasia Mutated, Homologous Recombination Repair, and the DNA Damage Response
  Cancer Research. Feb, 2007  |   Pubmed ID: 17283137
• Human Chorionic Gonadotropin Modulates Prostate Cancer Cell Survival After Irradiation or HMG CoA Reductase Inhibitor Treatment
  Molecular Pharmacology. Jan, 2007  |   Pubmed ID: 17050804
• N-glycosylation of MDA-7/IL-24 is Dispensable for Tumor Cell-specific Apoptosis and "bystander" Antitumor Activity
  Cancer Research. Dec, 2006  |   Pubmed ID: 17178884
• BiP/GRP78 is an Intracellular Target for MDA-7/IL-24 Induction of Cancer-specific Apoptosis
  Cancer Research. Aug, 2006  |   Pubmed ID: 16912197
• Effect of Hepatitis C Virus Core Protein on the Molecular Profiling of Human B Lymphocytes
  Molecular Medicine (Cambridge, Mass.). Jan-Mar, 2006  |   Pubmed ID: 16838065
• ErbB Receptor Tyrosine Kinase Network Inhibition Radiosensitizes Carcinoma Cells
  International Journal of Radiation Oncology, Biology, Physics. Jul, 2006  |   Pubmed ID: 16751066
• Molecular Target-based Therapy of Pancreatic Cancer
  Cancer Research. Feb, 2006  |   Pubmed ID: 16489047
• Activation of the Nuclear Factor KappaB Pathway by Astrocyte Elevated Gene-1: Implications for Tumor Progression and Metastasis
  Cancer Research. Feb, 2006  |   Pubmed ID: 16452207
• Compensatory ErbB3/c-Src Signaling Enhances Carcinoma Cell Survival to Ionizing Radiation
  Breast Cancer Research and Treatment. Jan, 2006  |   Pubmed ID: 16267617
• Mda-9/Syntenin: a Positive Regulator of Melanoma Metastasis
  Cancer Research. Dec, 2005  |   Pubmed ID: 16322237
• Radiosensitization of MDA-MB-231 Breast Tumor Cells by Adenovirus-mediated Overexpression of a Fragment of the XRCC4 Protein
  Molecular Cancer Therapeutics. Oct, 2005  |   Pubmed ID: 16227403
• Targeted Virus Replication Plus Immunotherapy Eradicates Primary and Distant Pancreatic Tumors in Nude Mice
  Cancer Research. Oct, 2005  |   Pubmed ID: 16204080
• Defining the Domains of Human Polynucleotide Phosphorylase (hPNPaseOLD-35) Mediating Cellular Senescence
  Molecular and Cellular Biology. Aug, 2005  |   Pubmed ID: 16055741
• Requirement of Tyr-992 and Tyr-1173 in Phosphorylation of the Epidermal Growth Factor Receptor by Ionizing Radiation and Modulation by SHP2
  The Journal of Biological Chemistry. Apr, 2005  |   Pubmed ID: 15708852
• Deficiency in 3'-phosphoglycolate Processing in Human Cells with a Hereditary Mutation in Tyrosyl-DNA Phosphodiesterase (TDP1)
  Nucleic Acids Research. 2005  |   Pubmed ID: 15647511
• Targeting Gene Expression Selectively in Cancer Cells by Using the Progression-elevated Gene-3 Promoter
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2005  |   Pubmed ID: 15647352
• Inhibition of the Type III Epidermal Growth Factor Receptor Variant Mutant Receptor by Dominant-negative EGFR-CD533 Enhances Malignant Glioma Cell Radiosensitivity
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2004  |   Pubmed ID: 15475464
• Radiation-induced Activation of a Common Variant of EGFR Confers Enhanced Radioresistance
  Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Sep, 2004  |   Pubmed ID: 15450724
• Melanoma Differentiation Associated Gene-7/interleukin-24 Promotes Tumor Cell-specific Apoptosis Through Both Secretory and Nonsecretory Pathways
  Cancer Research. May, 2004  |   Pubmed ID: 15126330
• Double Strand Break Repair by Homologous Recombination is Regulated by Cell Cycle-independent Signaling Via ATM in Human Glioma Cells
  The Journal of Biological Chemistry. Apr, 2004  |   Pubmed ID: 14744854
• Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, Mda-5: a Novel Type I Interferon-responsive Apoptosis-inducing Gene
  Oncogene. Mar, 2004  |   Pubmed ID: 14676839
• Activation of the Stress-activated JNK and P38 MAP Kinases in Human Cells by Photofrin-mediated Photodynamic Therapy
  Journal of Photochemistry and Photobiology. B, Biology. Oct, 2003  |   Pubmed ID: 14705642
• Curcumin Inhibits Ultraviolet Light Induced Human Immunodeficiency Virus Gene Expression
  Molecular and Cellular Biochemistry. Dec, 2003  |   Pubmed ID: 14674708
• Triggering of Apoptosis is Not Sufficient to Induce Human Immunodeficiency Virus Gene Expression
  IUBMB Life. Jul, 2003  |   Pubmed ID: 14584593
• Regulation and Mechanisms of Mammalian Double-strand Break Repair
  Oncogene. Sep, 2003  |   Pubmed ID: 12947387
• EGFRvIII-mediated Radioresistance Through a Strong Cytoprotective Response
  Oncogene. Aug, 2003  |   Pubmed ID: 12944901
• MDA-7 (interleukin-24) Inhibits the Proliferation of Renal Carcinoma Cells and Interacts with Free Radicals to Promote Cell Death and Loss of Reproductive Capacity
  Molecular Cancer Therapeutics. Jul, 2003  |   Pubmed ID: 12883035
• Involvement of Crm1 in Hepatitis B Virus X Protein-induced Aberrant Centriole Replication and Abnormal Mitotic Spindles
  Molecular and Cellular Biology. Aug, 2003  |   Pubmed ID: 12861014
• Adenovirus Expressing P53
  Methods in Molecular Biology (Clifton, N.J.). 2003  |   Pubmed ID: 12824521
• Dominant-negative CAMP-responsive Element-binding Protein Inhibits Proliferating Cell Nuclear Antigen and DNA Repair, Leading to Increased Cellular Radiosensitivity
  The Journal of Biological Chemistry. Aug, 2003  |   Pubmed ID: 12734192
• Down-regulation of Myc As a Potential Target for Growth Arrest Induced by Human Polynucleotide Phosphorylase (hPNPaseold-35) in Human Melanoma Cells
  The Journal of Biological Chemistry. Jul, 2003  |   Pubmed ID: 12721301
• Bile Acid Regulation of C/EBPbeta, CREB, and C-Jun Function, Via the Extracellular Signal-regulated Kinase and C-Jun NH2-terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes
  Molecular and Cellular Biology. May, 2003  |   Pubmed ID: 12697808
• Melanoma Differentiation Associated Gene-7, Mda-7/IL-24, Selectively Induces Growth Suppression, Apoptosis and Radiosensitization in Malignant Gliomas in a P53-independent Manner
  Oncogene. Feb, 2003  |   Pubmed ID: 12606943
• BLM Helicase-dependent Transport of P53 to Sites of Stalled DNA Replication Forks Modulates Homologous Recombination
  The EMBO Journal. Mar, 2003  |   Pubmed ID: 12606585
• Stress and Radiation-induced Activation of Multiple Intracellular Signaling Pathways
  Radiation Research. Mar, 2003  |   Pubmed ID: 12600231
• Mood-enhancing Antidepressant St. John's Wort Inhibits the Activation of Human Immunodeficiency Virus Gene Expression by Ultraviolet Light
  IUBMB Life. Dec, 2002  |   Pubmed ID: 12665247
• Identification and Cloning of Human Polynucleotide Phosphorylase, HPNPase Old-35, in the Context of Terminal Differentiation and Cellular Senescence
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002  |   Pubmed ID: 12473748
• SAGE Transcript Profiles of Normal Primary Human Hepatocytes Expressing Oncogenic Hepatitis B Virus X Protein
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2002  |   Pubmed ID: 12207007
• Epidermal Growth Factor Receptor Dependence of Radiation-induced Transcription Factor Activation in Human Breast Carcinoma Cells
  Molecular Biology of the Cell. Jul, 2002  |   Pubmed ID: 12134064
• Mda-7 (IL-24) Mediates Selective Apoptosis in Human Melanoma Cells by Inducing the Coordinated Overexpression of the GADD Family of Genes by Means of P38 MAPK
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2002  |   Pubmed ID: 12114539
• UVB-mediated Activation of P38 Mitogen-activated Protein Kinase Enhances Resistance of Normal Human Keratinocytes to Apoptosis by Stabilizing Cytoplasmic P53
  The Biochemical Journal. Jul, 2002  |   Pubmed ID: 12071847
• Ionizing Radiation Activates Erb-B Receptor Dependent Akt and P70 S6 Kinase Signaling in Carcinoma Cells
  Oncogene. Jun, 2002  |   Pubmed ID: 12037685
• Radiosensitization of Human Glioma Cells in Vitro and in Vivo with Acyclovir and Mutant HSV-TK75 Expressed from Adenovirus
  International Journal of Radiation Oncology, Biology, Physics. Mar, 2002  |   Pubmed ID: 11849808