L. James Lee

Publications

• ROR1-targeted Delivery of OSU-2S, a Nonimmunosuppressive FTY720 Derivative, Exerts Potent Cytotoxicity in Mantle-cell Lymphoma In vitro and In vivo
  Experimental Hematology. Apr, 2015  |   Pubmed ID: 25937048
• CD33-Targeted Lipid Nanoparticles (aCD33LNs) for Therapeutic Delivery of GTI-2040 to Acute Myelogenous Leukemia
  Molecular Pharmaceutics. Apr, 2015  |   Pubmed ID: 25871632
• Selective Targeting of Alveolar Type II Respiratory Epithelial Cells by Anti-surfactant Protein-C Antibody-conjugated Lipoplexes
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2015  |   Pubmed ID: 25687308
• Effect of Nonendocytic Uptake of Nanoparticles on Human Bronchial Epithelial Cells
  Analytical Chemistry. Mar, 2015  |   Pubmed ID: 25671340
• Magnetic Tweezers-Based 3D Microchannel Electroporation for High-Throughput Gene Transfection in Living Cells
  Small (Weinheim an Der Bergstrasse, Germany). Apr, 2015  |   Pubmed ID: 25469659
• Indole-3-carbinol Inhibits Tumorigenicity of Hepatocellular Carcinoma Cells Via Suppression of MicroRNA-21 and Upregulation of Phosphatase and Tensin Homolog
  Biochimica Et Biophysica Acta. Jan, 2015  |   Pubmed ID: 25447674
• Microwell Array-mediated Delivery of Lipoplexes Containing Nucleic Acids for Enhanced Therapeutic Efficacy
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 25319649
• Preparation and Evaluation of a Novel Liposomal Formulation of Cisplatin
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Oct, 2014  |   Pubmed ID: 25446511
• Targeted Delivery of Tumor Suppressor MicroRNA-1 by Transferrin-conjugated Lipopolyplex Nanoparticles to Patient-derived Glioblastoma Stem Cells
  Current Pharmaceutical Biotechnology. 2014  |   Pubmed ID: 25374033
• A Microfluidic Method to Synthesize Transferrin-lipid Nanoparticles Loaded with SiRNA LOR-1284 for Therapy of Acute Myeloid Leukemia
  Nanoscale. Aug, 2014  |   Pubmed ID: 25003978
• Quantification of OSU-2S, a Novel Derivative of FTY720, in Mouse Plasma by Liquid Chromatography-tandem Mass Spectrometry
  Journal of Pharmaceutical and Biomedical Analysis. Sep, 2014  |   Pubmed ID: 24927402
• Insight into Mechanisms of Cellular Uptake of Lipid Nanoparticles and Intracellular Release of Small RNAs
  Pharmaceutical Research. Oct, 2014  |   Pubmed ID: 24740244
• Microwell Array Guided Assembly of Lipoplex Nanoparticles Containing SiRNA
  Langmuir : the ACS Journal of Surfaces and Colloids. Mar, 2014  |   Pubmed ID: 24564319
• Design of a Microchannel-nanochannel-microchannel Array Based Nanoelectroporation System for Precise Gene Transfection
  Small (Weinheim an Der Bergstrasse, Germany). Mar, 2014  |   Pubmed ID: 24173879
• Epigenetic Regulation of Connective Tissue Growth Factor by MicroRNA-214 Delivery in Exosomes from Mouse or Human Hepatic Stellate Cells
  Hepatology (Baltimore, Md.). Mar, 2014  |   Pubmed ID: 24122827
• Nonendocytic Delivery of Lipoplex Nanoparticles into Living Cells Using Nanochannel Electroporation
  Advanced Healthcare Materials. May, 2014  |   Pubmed ID: 23996973
• A Novel Liposomal Formulation of FTY720 (fingolimod) for Promising Enhanced Targeted Delivery
  Nanomedicine : Nanotechnology, Biology, and Medicine. Feb, 2014  |   Pubmed ID: 23969101
• Enhanced Hepatic Delivery of SiRNA and MicroRNA Using Oleic Acid Based Lipid Nanoparticle Formulations
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2013  |   Pubmed ID: 24121065
• Detection of Extracellular RNAs in Cancer and Viral Infection Via Tethered Cationic Lipoplex Nanoparticles Containing Molecular Beacons
  Analytical Chemistry. Dec, 2013  |   Pubmed ID: 24102152
• Graphene-coated Si Mold for Precision Glass Optics Molding
  Optics Letters. Jul, 2013  |   Pubmed ID: 23939130
• Atomic Carbide Bonding Leading to Superior Graphene Networks
  Advanced Materials (Deerfield Beach, Fla.). Sep, 2013  |   Pubmed ID: 23852915
• Cationic Lipid Nanoparticles for Therapeutic Delivery of SiRNA and MiRNA to Murine Liver Tumor
  Nanomedicine : Nanotechnology, Biology, and Medicine. Nov, 2013  |   Pubmed ID: 23727126
• Targeted Drug Delivery and Cross-linking Induced Apoptosis with Anti-CD37 Based Dual-ligand Immunoliposomes in B Chronic Lymphocytic Leukemia Cells
  Biomaterials. Aug, 2013  |   Pubmed ID: 23726226
• Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer
  Molecular Therapy. Nucleic Acids. 2013  |   Pubmed ID: 23591808
• Surface-mediated Nucleic Acid Delivery by Lipoplexes Prepared in Microwell Arrays
  Small (Weinheim an Der Bergstrasse, Germany). Jul, 2013  |   Pubmed ID: 23471869
• Micro-/nanofluidics Based Cell Electroporation
  Biomicrofluidics. Jan, 2013  |   Pubmed ID: 23405056
• A Naonoporous Cell-therapy Device with Controllable Biodegradation for Long-term Drug Release
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2013  |   Pubmed ID: 23228849
• Comparative Cellular Pharmacokinetics and Pharmacodynamics of SiRNA Delivery by SPANosomes and by Cationic Liposomes
  Nanomedicine : Nanotechnology, Biology, and Medicine. May, 2013  |   Pubmed ID: 23117046
• Lenalidomide-mediated Enhanced Translation of C/EBPα-p30 Protein Up-regulates Expression of the Antileukemic MicroRNA-181a in Acute Myeloid Leukemia
  Blood. Jan, 2013  |   Pubmed ID: 23100311
• Targeted Nanoparticle Delivery Overcomes Off-target Immunostimulatory Effects of Oligonucleotides and Improves Therapeutic Efficacy in Chronic Lymphocytic Leukemia
  Blood. Nov, 2012  |   Pubmed ID: 23165478
• High-performance Nanopapers Based on Benzenesulfonic Functionalized Graphenes
  ACS Nano. Nov, 2012  |   Pubmed ID: 23098084
• Lactosylated Liposomes for Targeted Delivery of Doxorubicin to Hepatocellular Carcinoma
  International Journal of Nanomedicine. 2012  |   Pubmed ID: 23093902
• Micropatterned Thermoresponsive Surfaces by Polymerization of Monomer Crystals: Modulating Cellular Morphology and Cell-substrate Interactions
  Analytical Chemistry. Nov, 2012  |   Pubmed ID: 23025496
• Novel Lipoidal Amine-based Nanocarrier Formulations for SiRNA Delivery
  Therapeutic Delivery. Jun, 2012  |   Pubmed ID: 22838067
• The Prolonged Survival of Fibroblasts with Forced Lipid Catabolism in Visceral Fat Following Encapsulation in Alginate-poly-L-lysine
  Biomaterials. Aug, 2012  |   Pubmed ID: 22575837
• Micro/nanoscale Technologies for the Development of Hormone-expressing Islet-like Cell Clusters
  Biomedical Microdevices. Aug, 2012  |   Pubmed ID: 22573223
• Differential Efficacy of DOTAP Enantiomers for SiRNA Delivery in Vitro
  International Journal of Pharmaceutics. Jul, 2012  |   Pubmed ID: 22525086
• Efficient SiRNA Delivery Using a Polyamidoamine Dendrimer with a Modified Pentaerythritol Core
  Pharmaceutical Research. Jan, 2012  |   Pubmed ID: 22274556
• SPANosomes As Delivery Vehicles for Small Interfering RNA (siRNA)
  Molecular Pharmaceutics. Feb, 2012  |   Pubmed ID: 22149175
• Nanochannel Electroporation Delivers Precise Amounts of Biomolecules into Living Cells
  Nature Nanotechnology. Nov, 2011  |   Pubmed ID: 22002097
• Uptake and Intracellular Fate of Multifunctional Nanoparticles: a Comparison Between Lipoplexes and Polyplexes Via Quantum Dot Mediated Förster Resonance Energy Transfer
  Molecular Pharmaceutics. Oct, 2011  |   Pubmed ID: 21740056
• Liposomes Containing (-)-gossypol-enriched Cottonseed Oil Suppress Bcl-2 and Bcl-xL Expression in Breast Cancer Cells
  Pharmaceutical Research. Dec, 2011  |   Pubmed ID: 21710341
• MicroRNA Delivery by Cationic Lipoplexes for Lung Cancer Therapy
  Molecular Pharmaceutics. Aug, 2011  |   Pubmed ID: 21648427
• Efficient Down-regulation of CDK4 by Novel Lipid Nanoparticle-mediated SiRNA Delivery
  Anticancer Research. May, 2011  |   Pubmed ID: 21617218
• Microfluidic Assembly of Lipid-based Oligonucleotide Nanoparticles
  Anticancer Research. Mar, 2011  |   Pubmed ID: 21498694
• Electroporation Dependence on Cell Size: Optical Tweezers Study
  Analytical Chemistry. Jun, 2011  |   Pubmed ID: 21473595
• A Covalently Stabilized Lipid-polycation-DNA (sLPD) Vector for Antisense Oligonucleotide Delivery
  Molecular Pharmaceutics. Jun, 2011  |   Pubmed ID: 21366344
• Use of a Nanoporous Biodegradable Miniature Device to Regulate Cytokine Release for Cancer Treatment
  Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2011  |   Pubmed ID: 21362447
• Micropatterning and Characterization of Electrospun Poly(ε-caprolactone)/gelatin Nanofiber Tissue Scaffolds by Femtosecond Laser Ablation for Tissue Engineering Applications
  Biotechnology and Bioengineering. Jan, 2011  |   Pubmed ID: 20812254
• Receptor-targeted Nanocarriers for Therapeutic Delivery to Cancer
  Molecular Membrane Biology. Oct, 2010  |   Pubmed ID: 21028937
• Formation and Finite Element Analysis of Tethered Bilayer Lipid Structures
  Langmuir : the ACS Journal of Surfaces and Colloids. Dec, 2010  |   Pubmed ID: 20977245
• Patterning Nanowire and Micro-nanoparticle Array on Micropillar-structured Surface: Experiment and Modeling
  Biomicrofluidics. 2010  |   Pubmed ID: 20805999
• Large Laterally Ordered Nanochannel Arrays from DNA Combing and Imprinting
  Advanced Materials (Deerfield Beach, Fla.). Sep, 2010  |   Pubmed ID: 20730809
• Targeted Nanoparticles Enhanced Flow Electroporation of Antisense Oligonucleotides in Leukemia Cells
  Biosensors & Bioelectronics. Oct, 2010  |   Pubmed ID: 20630739
• Ultrasound-enhanced Microfluidic Synthesis of Liposomes
  Anticancer Research. Feb, 2010  |   Pubmed ID: 20332455
• High Throughput Assembly of Spatially Controlled 3D Cell Clusters on a Micro/nanoplatform
  Lab on a Chip. Mar, 2010  |   Pubmed ID: 20221567
• Lipid-coated Nano-calcium-phosphate (LNCP) for Gene Delivery
  International Journal of Pharmaceutics. Jun, 2010  |   Pubmed ID: 20214964
• Transferrin-conjugated Lipid-coated PLGA Nanoparticles for Targeted Delivery of Aromatase Inhibitor 7alpha-APTADD to Breast Cancer Cells
  International Journal of Pharmaceutics. May, 2010  |   Pubmed ID: 20156537
• Disulfide-linked Liposomes: Effective Delivery Vehicle for Bcl-2 Antisense Oligodeoxyribonucleotide G3139
  Anticancer Research. Jan, 2010  |   Pubmed ID: 20150614
• Nanoimprinting Using Self-assembled Ceramic Nanoislands
  Nanotechnology. Jan, 2010  |   Pubmed ID: 20009202
• Micronozzle Array Enhanced Sandwich Electroporation of Embryonic Stem Cells
  Analytical Chemistry. Jan, 2010  |   Pubmed ID: 19961232
• Targeted Delivery of Antisense Oligodeoxynucleotide by Transferrin Conjugated PH-sensitive Lipopolyplex Nanoparticles: a Novel Oligonucleotide-based Therapeutic Strategy in Acute Myeloid Leukemia
  Molecular Pharmaceutics. Feb, 2010  |   Pubmed ID: 19852511
• Coaxial Electrohydrodynamic Spraying of Plasmid DNA/polyethylenimine (PEI) Polyplexes for Enhanced Nonviral Gene Delivery
  Biotechnology and Bioengineering. Mar, 2010  |   Pubmed ID: 19845020
• Delivery of Antisense Oligodeoxyribonucleotide Lipopolyplex Nanoparticles Assembled by Microfluidic Hydrodynamic Focusing
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2010  |   Pubmed ID: 19716852
• Microfluidic Methods for Production of Liposomes
  Methods in Enzymology. 2009  |   Pubmed ID: 19913165
• Efficient Delivery of Antisense Oligodeoxyribonucleotide G3139 by Human Serum Albumin-coated Liposomes
  Molecular Pharmaceutics. Nov-Dec, 2009  |   Pubmed ID: 19725564
• Design and Testing of a Microfluidic Biochip for Cytokine Enzyme-linked Immunosorbent Assay
  Biomicrofluidics. 2009  |   Pubmed ID: 19693336
• Specific Antibody Immobilization with Biotin-poly(L-lysine)-g-poly(ethylene Glycol) and Protein A on Microfluidic Chips
  Journal of Immunological Methods. Oct, 2009  |   Pubmed ID: 19647744
• Delivery of Polyethylenimine/DNA Complexes Assembled in a Microfluidics Device
  Molecular Pharmaceutics. Sep-Oct, 2009  |   Pubmed ID: 19552481
• Single-molecule DNA Dynamics in Tapered Contraction-expansion Microchannels Under Electrophoresis
  Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Apr, 2009  |   Pubmed ID: 19518260
• Coaxial Electrohydrodynamic Spraying: a Novel One-step Technique to Prepare Oligodeoxynucleotide Encapsulated Lipoplex Nanoparticles
  Molecular Pharmaceutics. Sep-Oct, 2009  |   Pubmed ID: 19499922
• Preparation, Characterization and Pharmacokinetics of Folate Receptor-targeted Liposomes for Docetaxel Delivery
  Journal of Nanoscience and Nanotechnology. Mar, 2009  |   Pubmed ID: 19435095
• Semicontinuous Flow Electroporation Chip for High-throughput Transfection on Mammalian Cells
  Analytical Chemistry. Jun, 2009  |   Pubmed ID: 19419195
• Bioassembly of Three-dimensional Embryonic Stem Cell-scaffold Complexes Using Compressed Gases
  Biotechnology Progress. Mar-Apr, 2009  |   Pubmed ID: 19334083
• Targeted Delivery Systems for Oligonucleotide Therapeutics
  The AAPS Journal. Mar, 2009  |   Pubmed ID: 19296227
• Transferrin Receptor Targeted Lipopolyplexes for Delivery of Antisense Oligonucleotide G3139 in a Murine K562 Xenograft Model
  Pharmaceutical Research. Jun, 2009  |   Pubmed ID: 19291371
• Transferrin Receptor-targeted Lipid Nanoparticles for Delivery of an Antisense Oligodeoxyribonucleotide Against Bcl-2
  Molecular Pharmaceutics. Jan-Feb, 2009  |   Pubmed ID: 19183107
• Protein A-based Antibody Immobilization Onto Polymeric Microdevices for Enhanced Sensitivity of Enzyme-linked Immunosorbent Assay
  Biotechnology and Bioengineering. Feb, 2009  |   Pubmed ID: 18942150
• A Novel Liposomal Formulation of Flavopiridol
  International Journal of Pharmaceutics. Jan, 2009  |   Pubmed ID: 18778761
• Lenalidomide Down-regulates the CD20 Antigen and Antagonizes Direct and Antibody-dependent Cellular Cytotoxicity of Rituximab on Primary Chronic Lymphocytic Leukemia Cells
  Blood. Dec, 2008  |   Pubmed ID: 18772452
• A Biodegradable, Immunoprotective, Dual Nanoporous Capsule for Cell-based Therapies
  Biomaterials. Nov, 2008  |   Pubmed ID: 18694595
• A Facile Microfluidic Method for Production of Liposomes
  Anticancer Research. Mar-Apr, 2008  |   Pubmed ID: 18507040
• Cationic Lipid-coated Magnetic Nanoparticles Associated with Transferrin for Gene Delivery
  International Journal of Pharmaceutics. Jun, 2008  |   Pubmed ID: 18384982
• Electrokinetics Induced Asymmetric Transport in Polymeric Nanonozzles
  Lab on a Chip. Apr, 2008  |   Pubmed ID: 18369512
• Flow-guided Assembly Processes
  Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. May, 2008  |   Pubmed ID: 18351685
• Packaging of Microfluidic Chips Via Interstitial Bonding Technique
  Electrophoresis. Apr, 2008  |   Pubmed ID: 18318005
• A Novel Raji-Burkitt's Lymphoma Model for Preclinical and Mechanistic Evaluation of CD52-targeted Immunotherapeutic Agents
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2008  |   Pubmed ID: 18223233
• Growth and Alignment of Polyaniline Nanofibres with Superhydrophobic, Superhydrophilic and Other Properties
  Nature Nanotechnology. Jun, 2007  |   Pubmed ID: 18654306
• Gene Transfection of Mammalian Cells Using Membrane Sandwich Electroporation
  Analytical Chemistry. Aug, 2007  |   Pubmed ID: 17600386
• Hydrophilic Surface Modification of Cyclic Olefin Copolymer Microfluidic Chips Using Sequential Photografting
  Journal of Separation Science. May, 2007  |   Pubmed ID: 17566345
• Fabrication of Particulate Reservoir-containing, Capsulelike, and Self-folding Polymer Microstructures for Drug Delivery
  Small (Weinheim an Der Bergstrasse, Germany). Mar, 2007  |   Pubmed ID: 17285662
• New Valve and Bonding Designs for Microfluidic Biochips Containing Proteins
  Analytical Chemistry. Feb, 2007  |   Pubmed ID: 17263327
• Dynamic Assembly by Electrokinetic Microfluidics
  Journal of the American Chemical Society. Jan, 2007  |   Pubmed ID: 17212387
• Microfluidic Enzyme-linked Immunosorbent Assay Technology
  Advances in Clinical Chemistry. 2006  |   Pubmed ID: 17131629
• Assembly of Three-dimensional Polymeric Constructs Containing Cells/biomolecules Using Carbon Dioxide
  Journal of the American Chemical Society. Nov, 2006  |   Pubmed ID: 17061882
• Surface Modification for Enhancing Antibody Binding on Polymer-based Microfluidic Device for Enzyme-linked Immunosorbent Assay
  Langmuir : the ACS Journal of Surfaces and Colloids. Oct, 2006  |   Pubmed ID: 17042569
• Polymer Nano-engineering for Biomedical Applications
  Annals of Biomedical Engineering. Jan, 2006  |   Pubmed ID: 16541328
• Self-folding of Three-dimensional Hydrogel Microstructures
  The Journal of Physical Chemistry. B. Dec, 2005  |   Pubmed ID: 16375273
• Generating Highly Ordered DNA Nanostrand Arrays
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2005  |   Pubmed ID: 16352724
• Fabrication of Well-defined PLGA Scaffolds Using Novel Microembossing and Carbon Dioxide Bonding
  Biomaterials. May, 2005  |   Pubmed ID: 15585261
• Design of a Compact Disk-like Microfluidic Platform for Enzyme-linked Immunosorbent Assay
  Analytical Chemistry. Apr, 2004  |   Pubmed ID: 15053640
• Design of a Novel Hydrogel-based Intelligent System for Controlled Drug Release
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2004  |   Pubmed ID: 15023451
• A Packaging Technique for Polymer Microfluidic Platforms
  Analytical Chemistry. Feb, 2004  |   Pubmed ID: 14961752