Larisa Y. Poluektova

Publications

• Eluted 25-hydroxyvitamin D from Radially Aligned Nanofiber Scaffolds Enhances Cathelicidin Production While Reducing Inflammatory Response in Human Immune System-engrafted Mice
  Acta Biomaterialia. Aug, 2019  |   Pubmed ID: 31386930
• Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice
  Nature Communications. 07, 2019  |   Pubmed ID: 31266936
• Small Molecule ONC201 Inhibits HIV-1 Replication in Macrophages Via FOXO3a and TRAIL
  Antiviral Research. Aug, 2019  |   Pubmed ID: 31158413
• Acetaldehyde Suppresses the Display of HBV-MHC Class I Complexes on HBV-expressing Hepatocytes
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2019  |   Pubmed ID: 31141391
• Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice
  Frontiers in Immunology. 2019  |   Pubmed ID: 30873181
• Human Interleukin-34 Facilitates Microglia-like Cell Differentiation and Persistent HIV-1 Infection in Humanized Mice
  Molecular Neurodegeneration. 03, 2019  |   Pubmed ID: 30832693
• Human Immunodeficiency Virus and Hepatotropic Viruses Co-morbidities As the Inducers of Liver Injury Progression
  World Journal of Gastroenterology. Jan, 2019  |   Pubmed ID: 30700937
• Human-like NSG Mouse Glycoproteins Sialylation Pattern Changes the Phenotype of Human Lymphocytes and Sensitivity to HIV-1 Infection
  BMC Immunology. 01, 2019  |   Pubmed ID: 30616506
• Liver As a Target of Human Immunodeficiency Virus Infection
  World Journal of Gastroenterology. Nov, 2018  |   Pubmed ID: 30479460
• Hepatitis C Virus-Infected Apoptotic Hepatocytes Program Macrophages and Hepatic Stellate Cells for Liver Inflammation and Fibrosis Development: Role of Ethanol As a Second Hit
  Biomolecules. 10, 2018  |   Pubmed ID: 30322122
• Persistent EcoHIV Infection Induces Nigral Degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated Mice
  Journal of Neurovirology. Aug, 2018  |   Pubmed ID: 29594983
• Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice
  The Journal of Pharmacology and Experimental Therapeutics. 05, 2018  |   Pubmed ID: 29476044
• Creation of a Long-acting Nanoformulated Dolutegravir
  Nature Communications. 02, 2018  |   Pubmed ID: 29402886
• Human Hepatocyte Depletion in the Presence of HIV-1 Infection in Dual Reconstituted Humanized Mice
  Biology Open. Feb, 2018  |   Pubmed ID: 29361613
• Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains
  Disease Models & Mechanisms. 12, 2017  |   Pubmed ID: 29084769
• Sonic Hedgehog Mimetic Prevents Leukocyte Infiltration into the CNS During Acute HIV Infection
  Scientific Reports. 08, 2017  |   Pubmed ID: 28852071
• A Mature Macrophage is a Principal HIV-1 Cellular Reservoir in Humanized Mice After Treatment with Long Acting Antiretroviral Therapy
  Retrovirology. 03, 2017  |   Pubmed ID: 28279181
• Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18
  Alcoholism, Clinical and Experimental Research. 11, 2016  |   Pubmed ID: 27716962
• Neuropharmacologic Approaches to Restore the Brain's Microenvironment
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. 09, 2016  |   Pubmed ID: 27352074
• Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice
  Scientific Reports. 05, 2016  |   Pubmed ID: 27241024
• Simple and Reliable Genotyping Protocol for Mouse Prkdc(SCID) Mutation
  Journal of Immunological Methods. Apr, 2016  |   Pubmed ID: 26851521
• Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary
  AIDS Research and Human Retroviruses. Feb, 2016  |   Pubmed ID: 26670361
• The Mixed Lineage Kinase-3 Inhibitor URMC-099 Improves Therapeutic Outcomes for Long-acting Antiretroviral Therapy
  Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2016  |   Pubmed ID: 26472049
• Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice
  Molecular Neurobiology. 07, 2016  |   Pubmed ID: 26063593
• Influence of Age, Irradiation and Humanization on NSG Mouse Phenotypes
  Biology Open. Sep, 2015  |   Pubmed ID: 26353862
• Liver-targeted Antiviral Peptide Nanocomplexes As Potential Anti-HCV Therapeutics
  Biomaterials. Nov, 2015  |   Pubmed ID: 26298393
• Pharmacodynamics of Long-acting Folic Acid-receptor Targeted Ritonavir-boosted Atazanavir Nanoformulations
  Biomaterials. Feb, 2015  |   Pubmed ID: 25522973
• Associations Between Brain Microstructures, Metabolites, and Cognitive Deficits During Chronic HIV-1 Infection of Humanized Mice
  Molecular Neurodegeneration. Dec, 2014  |   Pubmed ID: 25523827
• Human Hepatocytes and Hematolymphoid Dual Reconstitution in Treosulfan-conditioned UPA-NOG Mice
  The American Journal of Pathology. Jan, 2014  |   Pubmed ID: 24200850
• Nano-NRTIs Demonstrate Low Neurotoxicity and High Antiviral Activity Against HIV Infection in the Brain
  Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2014  |   Pubmed ID: 23845925
• Improved Visualization of Neuronal Injury Following Glial Activation by Manganese Enhanced MRI
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Sep, 2013  |   Pubmed ID: 23729245
• Combinatorial Assessments of Brain Tissue Metabolomics and Histopathology in Rodent Models of Human Immunodeficiency Virus Infection
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Dec, 2013  |   Pubmed ID: 23702663
• Antiviral Peptide Nanocomplexes As a Potential Therapeutic Modality for HIV/HCV Co-infection
  Biomaterials. May, 2013  |   Pubmed ID: 23403120
• Long-acting Nanoformulated Antiretroviral Therapy Elicits Potent Antiretroviral and Neuroprotective Responses in HIV-1-infected Humanized Mice
  AIDS (London, England). Nov, 2012  |   Pubmed ID: 22824628
• Cisplatin-loaded Core Cross-linked Micelles: Comparative Pharmacokinetics, Antitumor Activity, and Toxicity in Mice
  International Journal of Nanomedicine. 2012  |   Pubmed ID: 22745537
• Can Humanized Mice Reflect the Complex Pathobiology of HIV-Associated Neurocognitive Disorders?
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Jan, 2012  |   Pubmed ID: 22222956
• IL-23 in Infections, Inflammation, Autoimmunity and Cancer: Possible Role in HIV-1 and AIDS
  Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Mar, 2012  |   Pubmed ID: 21947740
• Loss of Neuronal Integrity During Progressive HIV-1 Infection of Humanized Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2011  |   Pubmed ID: 21368026
• Nano-NRTIs: Efficient Inhibitors of HIV Type-1 in Macrophages with a Reduced Mitochondrial Toxicity
  Antiviral Chemistry & Chemotherapy. Oct, 2010  |   Pubmed ID: 21045256
• CD8+ Cell Depletion Accelerates HIV-1 Immunopathology in Humanized Mice
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2010  |   Pubmed ID: 20495069
• Protection from the Toxicity of Diisopropylfluorophosphate by Adeno-associated Virus Expressing Acetylcholinesterase
  Toxicology and Applied Pharmacology. Jul, 2006  |   Pubmed ID: 16443250
• Neuroprotective Mechanisms of Lithium in Murine Human Immunodeficiency Virus-1 Encephalitis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2005  |   Pubmed ID: 16162919
• Macrophage-induced Inflammation Affects Hippocampal Plasticity and Neuronal Development in a Murine Model of HIV-1 Encephalitis
  Glia. Dec, 2005  |   Pubmed ID: 16078235
• Neuroregulatory Events Follow Adaptive Immune-mediated Elimination of HIV-1-infected Macrophages: Studies in a Murine Model of Viral Encephalitis
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004  |   Pubmed ID: 15187141
• OTK18 Expression in Brain Mononuclear Phagocytes Parallels the Severity of HIV-1 Encephalitis
  Journal of Neuroimmunology. May, 2004  |   Pubmed ID: 15081264
• Neuroprotective Activities of Sodium Valproate in a Murine Model of Human Immunodeficiency Virus-1 Encephalitis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003  |   Pubmed ID: 14534250
• Generation of Cytotoxic T Cells Against Virus-infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2002  |   Pubmed ID: 11937550