Larisa Y. Poluektova Department of Pharmacology and Experimental Neuroscience University of Nebraska Medical Center Biography Publications Institution JoVE Articles Larisa Y. Poluektova has not added a biography. If you are Larisa Y. Poluektova and would like to personalize this page please email our Author Liaison for assistance. Publications Eluted 25-hydroxyvitamin D from Radially Aligned Nanofiber Scaffolds Enhances Cathelicidin Production While Reducing Inflammatory Response in Human Immune System-engrafted Mice Acta Biomaterialia. Aug, 2019 | Pubmed ID: 31386930 Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice Nature Communications. 07, 2019 | Pubmed ID: 31266936 Small Molecule ONC201 Inhibits HIV-1 Replication in Macrophages Via FOXO3a and TRAIL Antiviral Research. Aug, 2019 | Pubmed ID: 31158413 Acetaldehyde Suppresses the Display of HBV-MHC Class I Complexes on HBV-expressing Hepatocytes American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2019 | Pubmed ID: 31141391 Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice Frontiers in Immunology. 2019 | Pubmed ID: 30873181 Human Interleukin-34 Facilitates Microglia-like Cell Differentiation and Persistent HIV-1 Infection in Humanized Mice Molecular Neurodegeneration. 03, 2019 | Pubmed ID: 30832693 Human Immunodeficiency Virus and Hepatotropic Viruses Co-morbidities As the Inducers of Liver Injury Progression World Journal of Gastroenterology. Jan, 2019 | Pubmed ID: 30700937 Human-like NSG Mouse Glycoproteins Sialylation Pattern Changes the Phenotype of Human Lymphocytes and Sensitivity to HIV-1 Infection BMC Immunology. 01, 2019 | Pubmed ID: 30616506 Liver As a Target of Human Immunodeficiency Virus Infection World Journal of Gastroenterology. Nov, 2018 | Pubmed ID: 30479460 Hepatitis C Virus-Infected Apoptotic Hepatocytes Program Macrophages and Hepatic Stellate Cells for Liver Inflammation and Fibrosis Development: Role of Ethanol As a Second Hit Biomolecules. 10, 2018 | Pubmed ID: 30322122 Persistent EcoHIV Infection Induces Nigral Degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated Mice Journal of Neurovirology. Aug, 2018 | Pubmed ID: 29594983 Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice The Journal of Pharmacology and Experimental Therapeutics. 05, 2018 | Pubmed ID: 29476044 Creation of a Long-acting Nanoformulated Dolutegravir Nature Communications. 02, 2018 | Pubmed ID: 29402886 Human Hepatocyte Depletion in the Presence of HIV-1 Infection in Dual Reconstituted Humanized Mice Biology Open. Feb, 2018 | Pubmed ID: 29361613 Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains Disease Models & Mechanisms. 12, 2017 | Pubmed ID: 29084769 Sonic Hedgehog Mimetic Prevents Leukocyte Infiltration into the CNS During Acute HIV Infection Scientific Reports. 08, 2017 | Pubmed ID: 28852071 A Mature Macrophage is a Principal HIV-1 Cellular Reservoir in Humanized Mice After Treatment with Long Acting Antiretroviral Therapy Retrovirology. 03, 2017 | Pubmed ID: 28279181 Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18 Alcoholism, Clinical and Experimental Research. 11, 2016 | Pubmed ID: 27716962 Neuropharmacologic Approaches to Restore the Brain's Microenvironment Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. 09, 2016 | Pubmed ID: 27352074 Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice Scientific Reports. 05, 2016 | Pubmed ID: 27241024 Simple and Reliable Genotyping Protocol for Mouse Prkdc(SCID) Mutation Journal of Immunological Methods. Apr, 2016 | Pubmed ID: 26851521 Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary AIDS Research and Human Retroviruses. Feb, 2016 | Pubmed ID: 26670361 The Mixed Lineage Kinase-3 Inhibitor URMC-099 Improves Therapeutic Outcomes for Long-acting Antiretroviral Therapy Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2016 | Pubmed ID: 26472049 Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice Molecular Neurobiology. 07, 2016 | Pubmed ID: 26063593 Influence of Age, Irradiation and Humanization on NSG Mouse Phenotypes Biology Open. Sep, 2015 | Pubmed ID: 26353862 Liver-targeted Antiviral Peptide Nanocomplexes As Potential Anti-HCV Therapeutics Biomaterials. Nov, 2015 | Pubmed ID: 26298393 Pharmacodynamics of Long-acting Folic Acid-receptor Targeted Ritonavir-boosted Atazanavir Nanoformulations Biomaterials. Feb, 2015 | Pubmed ID: 25522973 Associations Between Brain Microstructures, Metabolites, and Cognitive Deficits During Chronic HIV-1 Infection of Humanized Mice Molecular Neurodegeneration. Dec, 2014 | Pubmed ID: 25523827 Human Hepatocytes and Hematolymphoid Dual Reconstitution in Treosulfan-conditioned UPA-NOG Mice The American Journal of Pathology. Jan, 2014 | Pubmed ID: 24200850 Nano-NRTIs Demonstrate Low Neurotoxicity and High Antiviral Activity Against HIV Infection in the Brain Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2014 | Pubmed ID: 23845925 Improved Visualization of Neuronal Injury Following Glial Activation by Manganese Enhanced MRI Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Sep, 2013 | Pubmed ID: 23729245 Combinatorial Assessments of Brain Tissue Metabolomics and Histopathology in Rodent Models of Human Immunodeficiency Virus Infection Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Dec, 2013 | Pubmed ID: 23702663 Antiviral Peptide Nanocomplexes As a Potential Therapeutic Modality for HIV/HCV Co-infection Biomaterials. May, 2013 | Pubmed ID: 23403120 Long-acting Nanoformulated Antiretroviral Therapy Elicits Potent Antiretroviral and Neuroprotective Responses in HIV-1-infected Humanized Mice AIDS (London, England). Nov, 2012 | Pubmed ID: 22824628 Cisplatin-loaded Core Cross-linked Micelles: Comparative Pharmacokinetics, Antitumor Activity, and Toxicity in Mice International Journal of Nanomedicine. 2012 | Pubmed ID: 22745537 Können Humanisierte Mäuse Die Komplexen Pathobiologie Der HIV-assoziierten Neurokognitiven Störungen Wiedergeben? Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Jan, 2012 | Pubmed ID: 22222956 IL-23 in Infections, Inflammation, Autoimmunity and Cancer: Possible Role in HIV-1 and AIDS Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Mar, 2012 | Pubmed ID: 21947740 Verlust Der Neuronale Integrität Während Der Progressiven HIV-1 Infektion Humanisierte Mäuse The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2011 | Pubmed ID: 21368026 Nano-NRTIs: Efficient Inhibitors of HIV Type-1 in Macrophages with a Reduced Mitochondrial Toxicity Antiviral Chemistry & Chemotherapy. Oct, 2010 | Pubmed ID: 21045256 CD8 + Zellen Erschöpfung Beschleunigt HIV-1 Immunpathologie Humanisierte Mäusen Journal of Immunology (Baltimore, Md. : 1950). Jun, 2010 | Pubmed ID: 20495069 Protection from the Toxicity of Diisopropylfluorophosphate by Adeno-associated Virus Expressing Acetylcholinesterase Toxicology and Applied Pharmacology. Jul, 2006 | Pubmed ID: 16443250 Neuroprotektive Mechanismen Von Lithium in Murinen Human-Immunodeficiency-Virus-1-Enzephalitis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2005 | Pubmed ID: 16162919 Makrophagen-induzierte Entzündung Betrifft Hippokampalen Plastizität Und Neuronale Entwicklung in Einem Mausmodell Der HIV-1-Enzephalitis Glia. Dec, 2005 | Pubmed ID: 16078235 Neuroregulatory Ereignisse Folgen Adaptive Immunvermittelte Eliminierung Von HIV-1-infizierten Makrophagen: Untersuchungen in Einem Mausmodell Der Virale Enzephalitis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15187141 OTK18 Expression Im Gehirn Mononukleären Phagozyten Wesentlichen Der Schwere Der HIV-1-Enzephalitis Journal of Neuroimmunology. May, 2004 | Pubmed ID: 15081264 Neuroprotektive Wirkungen Von Valproinsäure in Einem Mausmodell Der Humanen Immundefizienz-Virus-1-Enzephalitis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003 | Pubmed ID: 14534250 Bildung Von Zytotoxischen T-Zellen Gegen Virus-infizierten Menschlichen Gehirns Makrophagen in Einem Mausmodell Von HIV-1 Enzephalitis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2002 | Pubmed ID: 11937550 Etablierung des dualen humanisierten TK-NOG-Mausmodells für HIV-assoziierte Leberpathogenese Raghubendra Singh Dagur1, Weimin Wang1, Edward Makarov1, Yimin Sun2, Larisa Y. Poluektova1 1Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 2Department of Pathology and Microbiology, University of Nebraska Medical Center JoVE 58645 Immunology and Infection
Etablierung des dualen humanisierten TK-NOG-Mausmodells für HIV-assoziierte Leberpathogenese Raghubendra Singh Dagur1, Weimin Wang1, Edward Makarov1, Yimin Sun2, Larisa Y. Poluektova1 1Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 2Department of Pathology and Microbiology, University of Nebraska Medical Center JoVE 58645 Immunology and Infection