Larry D. Unsworth Department of Chemical and Materials Engineering, Donadeo Innovation Centre for Engineering University of Alberta Biography Publications Institution JoVE Articles Larry D. Unsworth has not added a biography. If you are Larry D. Unsworth and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Short Peptide Sequences That Activate Human Mast Cells Via Mas-related G-protein Coupled Receptor Member X2 Acta Biomaterialia. Sep, 2021 | Pubmed ID: 34530142 Effect of Amino Acid Composition of Elastin-like Polypeptide Nanoparticles on Nonspecific Protein Adsorption, Macrophage Cell Viability and Phagocytosis Biopolymers. Aug, 2021 | Pubmed ID: 34363693 Effect of Carbamylation on Protein Structure and Adsorption to Self-assembled Monolayer Surfaces Colloids and Surfaces. B, Biointerfaces. Jul, 2021 | Pubmed ID: 33831751 Phage-Display-Derived Peptide Specific to Carbamylated Protein ACS Omega. Feb, 2021 | Pubmed ID: 33553925 Drug Delivery Platforms for Neonatal Brain Injury Journal of Controlled Release : Official Journal of the Controlled Release Society. 02, 2021 | Pubmed ID: 33417984 Structural Polymorphisms in Fibrillar Aggregates Associated with Exfoliation Syndrome Scientific Reports. 09, 2020 | Pubmed ID: 32985538 Polymer-coated Nanoparticle Protein Corona Formation Potentiates Phagocytosis of Bacteria by Innate Immune Cells and Inhibits Coagulation in Human Plasma Biointerphases. 09, 2020 | Pubmed ID: 32957792 The Possible Uses and Challenges of Nanomaterials in Mast Cell Research Journal of Immunology (Baltimore, Md. : 1950). 04, 2020 | Pubmed ID: 32253270 Human Plasma Protein Adsorption to Elastinlike Polypeptide Nanoparticles Biointerphases. 03, 2020 | Pubmed ID: 32228004 Recent Advances in Risk Factors Associated with Ocular Exfoliation Syndrome Acta Ophthalmologica. Mar, 2020 | Pubmed ID: 31736276 Sustained Release of Dexamethasone from Sulfobutyl Ether β-cyclodextrin Modified Self-Assembling Peptide Nanoscaffolds in a Perinatal Rat Model of Hypoxia-Ischemia Advanced Healthcare Materials. 06, 2019 | Pubmed ID: 30977596 Charge and Peptide Concentration As Determinants of the Hydrogel Internal Aqueous Environment Materials (Basel, Switzerland). Mar, 2019 | Pubmed ID: 30870997 Enzymatic Activity in Fractal Networks of Self-Assembling Peptides Biomacromolecules. 01, 2019 | Pubmed ID: 30457842 Towards Developing Bioresponsive, Self-Assembled Peptide Materials: Dynamic Morphology and Fractal Nature of Nanostructured Matrices Materials (Basel, Switzerland). Aug, 2018 | Pubmed ID: 30150517 Self-assembly/disassembly Hysteresis of Nanoparticles Composed of Marginally Soluble, Short Elastin-like Polypeptides Journal of Nanobiotechnology. Feb, 2018 | Pubmed ID: 29454362 Self-Assembling Peptide Nanoscaffold That Activates Human Mast Cells ACS Applied Materials & Interfaces. Feb, 2018 | Pubmed ID: 29308881 Peptides for Targeting βB2-crystallin Fibrils Experimental Eye Research. 12, 2017 | Pubmed ID: 28986145 The Spontaneous Adhesion of BMMC Onto Self-Assembled Peptide Nanoscaffold Without Activation Inhibits Its IgE-Mediated Degranulation Advanced Healthcare Materials. Jun, 2017 | Pubmed ID: 28665558 Peptide-mediated Mast Cell Activation: Ligand Similarities for Receptor Recognition and Protease-induced Regulation Journal of Leukocyte Biology. Aug, 2017 | Pubmed ID: 28606938 UV-B Induced Fibrillization of Crystallin Protein Mixtures PloS One. 2017 | Pubmed ID: 28542382 Using Properties of Tumor Microenvironments for Controlling Local, On-Demand Delivery from Biopolymer-Based Nanocarriers Current Pharmaceutical Design. 2017 | Pubmed ID: 28530543 RANKL Release from Self-assembling Nanofiber Hydrogels for Inducing Osteoclastogenesis in Vitro Acta Biomaterialia. Feb, 2017 | Pubmed ID: 27940164 High-yield Recombinant Expression and Purification of Marginally Soluble, Short Elastin-like Polypeptides BioTechniques. 12, 2016 | Pubmed ID: 27938321 Induced Neural Differentiation of MMP-2 Cleaved (RADA) Drug Delivery Systems Journal of Controlled Release : Official Journal of the Controlled Release Society. 12, 2016 | Pubmed ID: 27720765 Neural Tissue Engineering: Bioresponsive Nanoscaffolds Using Engineered Self-assembling Peptides Acta Biomaterialia. 10, 2016 | Pubmed ID: 27544809 PH-Triggered Release of Hydrophobic Molecules from Self-Assembling Hybrid Nanoscaffolds Biomacromolecules. Apr, 2016 | Pubmed ID: 26938197 Brain Biocompatibility and Microglia Response Towards Engineered Self-assembling (RADA)4 Nanoscaffolds Acta Biomaterialia. Apr, 2016 | Pubmed ID: 26850147 Evaluation of the Hemocompatibility and Rapid Hemostasis of (RADA)4 Peptide-based Hydrogels Acta Biomaterialia. Feb, 2016 | Pubmed ID: 26654763 Cleft Palate Reconstruction Using Collagen and Nanofiber Scaffold Incorporating Bone Morphogenetic Protein in Rats Tissue Engineering. Part A. Jan, 2015 | Pubmed ID: 24943898 Application of Isothermal Titration Calorimetry for Characterizing Thermodynamic Parameters of Biomolecular Interactions: Peptide Self-assembly and Protein Adsorption Case Studies Biomacromolecules. Oct, 2014 | Pubmed ID: 25131962 Toward a Mechanistic Understanding of Ionic Self-complementary Peptide Self-assembly: Role of Water Molecules and Ions Biomacromolecules. Nov, 2013 | Pubmed ID: 24053544 Understanding the Effect of Secondary Structure on Molecular Interactions of Poly-L-lysine with Different Substrates by SFA Biomacromolecules. Oct, 2013 | Pubmed ID: 24032485 Bioactive Glass 45S5 Powders: Effect of Synthesis Route and Resultant Surface Chemistry and Crystallinity on Protein Adsorption from Human Plasma Biointerphases. Dec, 2012 | Pubmed ID: 22669582 Plasma Protein Adsorption to Zwitterionic Poly (carboxybetaine Methacrylate) Modified Surfaces: Chain Chemistry and End-group Effects on Protein Adsorption Kinetics, Adsorbed Amounts and Immunoblots Biointerphases. Dec, 2012 | Pubmed ID: 22665019 Nanostructured, Self-assembling Peptide K5 Blocks TNF-α and PGE₂ Production by Suppression of the AP-1/p38 Pathway Mediators of Inflammation. 2012 | Pubmed ID: 22315508 Engineered Peptides with Enzymatically Cleavable Domains for Controlling the Release of Model Protein Drug from "soft" Nanoparticles Acta Biomaterialia. Feb, 2012 | Pubmed ID: 22062019 Poly(carboxybetaine Methacrylamide)-modified Nanoparticles: a Model System for Studying the Effect of Chain Chemistry on Film Properties, Adsorbed Protein Conformation, and Clot Formation Kinetics Biomacromolecules. Oct, 2011 | Pubmed ID: 21892823 Poly-L-lysine-coated Albumin Nanoparticles: Stability, Mechanism for Increasing in Vitro Enzymatic Resilience, and SiRNA Release Characteristics Acta Biomaterialia. Nov, 2010 | Pubmed ID: 20601248 Controlled Release of Functional Proteins Through Designer Self-assembling Peptide Nanofiber Hydrogel Scaffold Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19273853 Hyperthermophilic Enzymes--stability, Activity and Implementation Strategies for High Temperature Applications The FEBS Journal. Aug, 2007 | Pubmed ID: 17683334 Screeningpeptider som aktiverer MRGPRX2 ved hjelp av konstruerte HEK-celler Shammy Raj1, Lei Lu2, Larry D. Unsworth1 1Department of Chemical and Materials Engineering, Donadeo Innovation Centre for Engineering, University of Alberta, 2School of Life Science and Engineering, Southwest Jiaotong University JoVE 62448 Immunology and Infection
Screeningpeptider som aktiverer MRGPRX2 ved hjelp av konstruerte HEK-celler Shammy Raj1, Lei Lu2, Larry D. Unsworth1 1Department of Chemical and Materials Engineering, Donadeo Innovation Centre for Engineering, University of Alberta, 2School of Life Science and Engineering, Southwest Jiaotong University JoVE 62448 Immunology and Infection