Laurent Bartholin INSERM U1052 Centre de Recherche en Cancérologie de Lyon Biography Publications Institution JoVE Articles Laurent Bartholin has not added a biography. If you are Laurent Bartholin and would like to personalize this page please email our Author Liaison for assistance. Publications The Conditional Expression of KRAS G12D in Mouse Pancreas Induces Disorganization of Endocrine Islets Prior the Onset of Ductal Pre-cancerous Lesions Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]. May-Jun, 2013 | Pubmed ID: 23719586 Generation of a Conditional Mouse Model to Target Acvr1b Disruption in Adult Tissues Genesis (New York, N.Y. : 2000). Feb, 2013 | Pubmed ID: 23109354 Homotypic Cell Cannibalism, a Cell-death Process Regulated by the Nuclear Protein 1, Opposes to Metastasis in Pancreatic Cancer EMBO Molecular Medicine. Sep, 2012 | Pubmed ID: 22821859 The Human NUPR1/P8 Gene is Transcriptionally Activated by Transforming Growth Factor β Via the SMAD Signalling Pathway The Biochemical Journal. Jul, 2012 | Pubmed ID: 22738338 Premature Senescence and Increased TGFβ Signaling in the Absence of Tgif1 PloS One. 2012 | Pubmed ID: 22514746 Tif1γ Suppresses Murine Pancreatic Tumoral Transformation by a Smad4-independent Pathway The American Journal of Pathology. Jun, 2012 | Pubmed ID: 22469842 A Rapid Strategy to Detect the Recombined Allele in LSL-TβRICA Transgenic Mice Genesis (New York, N.Y. : 2000). Sep, 2010 | Pubmed ID: 20645310 Inactivation of TIF1gamma Cooperates with Kras to Induce Cystic Tumors of the Pancreas PLoS Genetics. Jul, 2009 | Pubmed ID: 19629168 INKT Cell Development is Orchestrated by Different Branches of TGF-beta Signaling The Journal of Experimental Medicine. Jun, 2009 | Pubmed ID: 19451264 Generation of Mice with Conditionally Activated Transforming Growth Factor Beta Signaling Through the TbetaRI/ALK5 Receptor Genesis (New York, N.Y. : 2000). Dec, 2008 | Pubmed ID: 18821589 Maternal Tgif is Required for Vascularization of the Embryonic Placenta Developmental Biology. Jul, 2008 | Pubmed ID: 18508043 AF10-dependent Transcription is Enhanced by Its Interaction with FLRG Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Oct, 2007 | Pubmed ID: 17868029 Silencing of FLRG, an Antagonist of Activin, Inhibits Human Breast Tumor Cell Growth Cancer Research. Aug, 2007 | Pubmed ID: 17671190 Identification of NF-kappaB Responsive Elements in Follistatin Related Gene (FLRG) Promoter Gene. May, 2007 | Pubmed ID: 17395406 Functional Analysis of Mutations in TGIF Associated with Holoprosencephaly Molecular Genetics and Metabolism. Jan, 2007 | Pubmed ID: 16962354 The Human Cyr61 Gene is a Transcriptional Target of Transforming Growth Factor Beta in Cancer Cells Cancer Letters. Feb, 2007 | Pubmed ID: 16616811 TGIF Inhibits Retinoid Signaling Molecular and Cellular Biology. Feb, 2006 | Pubmed ID: 16428452 A Novel Role for Fibronectin Type I Domain in the Regulation of Human Hematopoietic Cell Adhesiveness Through Binding to Follistatin Domains of FLRG and Follistatin Experimental Cell Research. Feb, 2006 | Pubmed ID: 16336961 FLRG, a New ADAM12-associated Protein, Modulates Osteoclast Differentiation Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Jul, 2005 | Pubmed ID: 15574124 Drosophila TGIF Proteins Are Transcriptional Activators Molecular and Cellular Biology. Dec, 2003 | Pubmed ID: 14645536 Regulation of Human Erythropoiesis by Activin A, BMP2, and BMP4, Members of the TGFbeta Family Experimental Cell Research. Jan, 2003 | Pubmed ID: 12531697 Recurrent Involvement of the MLL Gene in Adult T-lineage Acute Lymphoblastic Leukemia Blood. Jun, 2002 | Pubmed ID: 12066788 Transcription Activation of FLRG and Follistatin by Activin A, Through Smad Proteins, Participates in a Negative Feedback Loop to Modulate Activin A Function Oncogene. Mar, 2002 | Pubmed ID: 11948405 Isolation and Culture of Mouse Primary Pancreatic Acinar Cells Johann Gout1,2,3,4,5, Roxane M. Pommier1,2,3,4,5, David F. Vincent1,2,3,4,5, Bastien Kaniewski1,2,3,4,5, Sylvie Martel1,2,3,4,5, Ulrich Valcourt*1,2,3,4,5, Laurent Bartholin*1,2,3,4,5 1INSERM U1052, Centre de Recherche en Cancérologie de Lyon, 2CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, 3Université de Lyon, 4Université Lyon 1, 5Centre Léon Bérard JoVE 50514 Biology
Isolation and Culture of Mouse Primary Pancreatic Acinar Cells Johann Gout1,2,3,4,5, Roxane M. Pommier1,2,3,4,5, David F. Vincent1,2,3,4,5, Bastien Kaniewski1,2,3,4,5, Sylvie Martel1,2,3,4,5, Ulrich Valcourt*1,2,3,4,5, Laurent Bartholin*1,2,3,4,5 1INSERM U1052, Centre de Recherche en Cancérologie de Lyon, 2CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, 3Université de Lyon, 4Université Lyon 1, 5Centre Léon Bérard JoVE 50514 Biology