Lawrence Steinman Department of Neurology and Neurological Sciences Stanford University Biography Publications Institution JoVE Articles Lawrence Steinman has not added a biography. If you are Lawrence Steinman and would like to personalize this page please email our Author Liaison for assistance. Publications Iron-sulfur Glutaredoxin 2 Protects Oligodendrocytes Against Damage Induced by Nitric Oxide Release from Activated Microglia Glia. Sep, 2017 | Pubmed ID: 28618115 Treatment with Anti-FcεRIα Antibody Exacerbates EAE and T-cell Immunity Against Myelin Neurology(R) Neuroimmunology & Neuroinflammation. May, 2017 | Pubmed ID: 28616446 Induction of New Autoimmune Diseases After Alemtuzumab Therapy for Multiple Sclerosis: Learning From Adversity JAMA Neurology. Aug, 2017 | Pubmed ID: 28604941 Adrenocorticotropic Hormone Versus Methylprednisolone Added to Interferon β in Patients with Multiple Sclerosis Experiencing Breakthrough Disease: a Randomized, Rater-blinded Trial Therapeutic Advances in Neurological Disorders. Jan, 2017 | Pubmed ID: 28450891 T Cell-Transfer Experimental Autoimmune Encephalomyelitis: Pillar of Multiple Sclerosis and Autoimmunity Journal of Immunology (Baltimore, Md. : 1950). May, 2017 | Pubmed ID: 28416715 PH20 is Not Expressed in Murine CNS and Oligodendrocyte Precursor Cells Annals of Clinical and Translational Neurology. Mar, 2017 | Pubmed ID: 28275653 Time Correlation Between Mononucleosis and Initial Symptoms of MS Neurology(R) Neuroimmunology & Neuroinflammation. May, 2017 | Pubmed ID: 28271078 Phosphorylation of αB-crystallin Supports Reactive Astrogliosis in Demyelination Proceedings of the National Academy of Sciences of the United States of America. Feb, 2017 | Pubmed ID: 28196893 Narcolepsy and Influenza Vaccination-induced Autoimmunity Annals of Translational Medicine. Jan, 2017 | Pubmed ID: 28164110 The Emergence of Neuroepidemiology, Neurovirology and Neuroimmunology: the Legacies of John F. Kurtzke and Richard 'Dick' T. Johnson Journal of Neurology. Apr, 2017 | Pubmed ID: 27734166 Tolerance Checkpoint Bypass Permits Emergence of Pathogenic T Cells to Neuromyelitis Optica Autoantigen Aquaporin-4 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2016 | Pubmed ID: 27940915 An Interferon-β-resistant and NLRP3 Inflammasome-independent Subtype of EAE with Neuronal Damage Nature Neuroscience. Dec, 2016 | Pubmed ID: 27820602 A Journey in Science: The Privilege of Exploring the Brain and the Immune System Molecular Medicine (Cambridge, Mass.). Jun, 2016 | Pubmed ID: 27652378 Genetic Background Modulates Outcome of Therapeutic Amyloid Peptides in Treatment of Neuroinflammation Journal of Neuroimmunology. Sep, 2016 | Pubmed ID: 27609274 CEACAM1 Mediates B Cell Aggregation in Central Nervous System Autoimmunity Scientific Reports. Jul, 2016 | Pubmed ID: 27435215 The Safety of Adjuvanted Vaccines Revisited: Vaccine-Induced Narcolepsy The Israel Medical Association Journal : IMAJ. Mar-Apr, 2016 | Pubmed ID: 27228647 Dimethyl Fumarate Treatment Induces Adaptive and Innate Immune Modulation Independent of Nrf2 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016 | Pubmed ID: 27078105 Identification of Candidate Tolerogenic CD8(+) T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model Journal of Diabetes Research. 2016 | Pubmed ID: 27069933 Mechanistic Insights into Influenza Vaccine-associated Narcolepsy Human Vaccines & Immunotherapeutics. Mar, 2016 | Pubmed ID: 27031682 Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes PloS One. 2016 | Pubmed ID: 27031512 Beginning of the End of Two-stage Theory Purporting That Inflammation then Degeneration Explains Pathogenesis of Progressive Multiple Sclerosis Current Opinion in Neurology. Jun, 2016 | Pubmed ID: 27027554 Cytokine Profiles Show Heterogeneity of Interferon-β Response in Multiple Sclerosis Patients Neurology(R) Neuroimmunology & Neuroinflammation. Apr, 2016 | Pubmed ID: 26894205 Multiplexed Autoantigen Microarrays Identify HLA As a Key Driver of Anti-desmoglein and -non-desmoglein Reactivities in Pemphigus Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26831096 Obeticholic Acid, a Synthetic Bile Acid Agonist of the Farnesoid X Receptor, Attenuates Experimental Autoimmune Encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26811456 Hyaluronan Synthesis is Necessary for Autoreactive T-cell Trafficking, Activation, and Th1 Polarization Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787861 Safety and Immunologic Effects of High- Vs Low-dose Cholecalciferol in Multiple Sclerosis Neurology. Jan, 2016 | Pubmed ID: 26718578 Amyloid Fibrils Activate B-1a Lymphocytes to Ameliorate Inflammatory Brain Disease Proceedings of the National Academy of Sciences of the United States of America. Dec, 2015 | Pubmed ID: 26621719 Response to Comment on "Antibodies to Influenza Nucleoprotein Cross-react with Human Hypocretin Receptor 2" Science Translational Medicine. Nov, 2015 | Pubmed ID: 26582897 Erratum To: Parsing Physiological Functions of Erythropoietin One Domain at a Time Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Oct, 2015 | Pubmed ID: 26358258 Parsing Physiological Functions of Erythropoietin One Domain at a Time Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Oct, 2015 | Pubmed ID: 26311151 Mir-181a-1/b-1 Modulates Tolerance Through Opposing Activities in Selection and Peripheral T Cell Function Journal of Immunology (Baltimore, Md. : 1950). Aug, 2015 | Pubmed ID: 26163591 Antibodies to Influenza Nucleoprotein Cross-react with Human Hypocretin Receptor 2 Science Translational Medicine. Jul, 2015 | Pubmed ID: 26136476 Tissue Transglutaminase Contributes to Experimental Multiple Sclerosis Pathogenesis and Clinical Outcome by Promoting Macrophage Migration Brain, Behavior, and Immunity. Nov, 2015 | Pubmed ID: 26133787 HDL-bound Sphingosine-1-phosphate Restrains Lymphopoiesis and Neuroinflammation Nature. Jul, 2015 | Pubmed ID: 26053123 Gaps in Knowledge and Prospects for Research of Adjuvanted Vaccines Vaccine. Jun, 2015 | Pubmed ID: 26022566 CD4 Cell Response to Interval Therapy with Natalizumab Annals of Clinical and Translational Neurology. May, 2015 | Pubmed ID: 26000328 Self-Assembling Peptides Form Immune Suppressive Amyloid Fibrils Effective in Autoimmune Encephalomyelitis Current Topics in Behavioral Neurosciences. 2015 | Pubmed ID: 25981913 Startups on the Menu: Atreca Nature Biotechnology. May, 2015 | Pubmed ID: 25965744 The Re-emergence of Antigen-specific Tolerance As a Potential Therapy for MS Multiple Sclerosis (Houndmills, Basingstoke, England). Sep, 2015 | Pubmed ID: 25921045 Critical Role for Prokineticin 2 in CNS Autoimmunity Neurology(R) Neuroimmunology & Neuroinflammation. Jun, 2015 | Pubmed ID: 25884014 No Quiet Surrender: Molecular Guardians in Multiple Sclerosis Brain The Journal of Clinical Investigation. Apr, 2015 | Pubmed ID: 25831441 B-lymphocyte-mediated Delayed Cognitive Impairment Following Stroke The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2015 | Pubmed ID: 25653369 IFN-β Treatment Requires B Cells for Efficacy in Neuroautoimmunity Journal of Immunology (Baltimore, Md. : 1950). Mar, 2015 | Pubmed ID: 25646307 Role Reversal: Infiltrating T Cells Protect the Brain The Journal of Clinical Investigation. Feb, 2015 | Pubmed ID: 25607835 Prolactin: a Versatile Regulator of Inflammation and Autoimmune Pathology Autoimmunity Reviews. Mar, 2015 | Pubmed ID: 25462579 A Century of Pavlovian Experiments Forming a Circuit from the Elucidation of Neural Reflexes to Pharmaceuticals and Electroceuticals to Treat Diseases Brain, Behavior, and Immunity. Feb, 2015 | Pubmed ID: 25451616 Going Viral and the Fatal Vulnerability of Neurons from Immunity, Not from Infection Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25422437 Conflicting Consequences of Immunity to Cancer Versus Autoimmunity to Neurons: Insights from Paraneoplastic Disease European Journal of Immunology. Nov, 2014 | Pubmed ID: 25319369 From Defining Antigens to New Therapies in Multiple Sclerosis: Honoring the Contributions of Ruth Arnon and Michael Sela Journal of Autoimmunity. Nov, 2014 | Pubmed ID: 25308417 Gene Expression Analysis of Histamine Receptors in Peripheral Blood Mononuclear Cells from Individuals with Clinically-isolated Syndrome and Different Stages of Multiple Sclerosis Journal of Neuroimmunology. Dec, 2014 | Pubmed ID: 25293806 Thymic Epithelium Determines a Spontaneous Chronic Neuritis in Icam1(tm1Jcgr)NOD Mice Journal of Immunology (Baltimore, Md. : 1950). Sep, 2014 | Pubmed ID: 25108020 Mechanisms of Action of Therapeutic Amyloidogenic Hexapeptides in Amelioration of Inflammatory Brain Disease The Journal of Experimental Medicine. Aug, 2014 | Pubmed ID: 25073790 Cerebrospinal Fluid Aquaporin-4 Antibody Levels in Neuromyelitis Optica Attacks Annals of Neurology. Aug, 2014 | Pubmed ID: 24977390 Development of Therapies for Autoimmune Disease at Stanford: a Tale of Multiple Shots and One Goal Immunologic Research. May, 2014 | Pubmed ID: 24771483 Janus Faces of Amyloid Proteins in Neuroinflammation Journal of Clinical Immunology. Jul, 2014 | Pubmed ID: 24711007 Uncovering Cryptic Glycan Markers in Multiple Sclerosis (MS) and Experimental Autoimmune Encephalomyelitis (EAE) Drug Development Research. May, 2014 | Pubmed ID: 24648292 Narcolepsy, 2009 A(H1N1) Pandemic Influenza, and Pandemic Influenza Vaccinations: What is Known and Unknown About the Neurological Disorder, the Role for Autoimmunity, and Vaccine Adjuvants Journal of Autoimmunity. May, 2014 | Pubmed ID: 24559657 Neither T-helper Type 2 nor Foxp3+ Regulatory T Cells Are Necessary for Therapeutic Benefit of Atorvastatin in Treatment of Central Nervous System Autoimmunity Journal of Neuroinflammation. Feb, 2014 | Pubmed ID: 24498870 Antiviral Drug Ganciclovir is a Potent Inhibitor of Microglial Proliferation and Neuroinflammation The Journal of Experimental Medicine. Feb, 2014 | Pubmed ID: 24493798 Mechanism of Metabolic Stroke and Spontaneous Cerebral Hemorrhage in Glutaric Aciduria Type I Acta Neuropathologica Communications. Jan, 2014 | Pubmed ID: 24468193 Immunology of Relapse and Remission in Multiple Sclerosis Annual Review of Immunology. 2014 | Pubmed ID: 24438352 Science Communication to the General Public: Why We Need to Teach Undergraduate and Graduate Students This Skill As Part of Their Formal Scientific Training Journal of Undergraduate Neuroscience Education : JUNE : a Publication of FUN, Faculty for Undergraduate Neuroscience. 2013 | Pubmed ID: 24319399 Clinical Optimization of Antigen Specific Modulation of Type 1 Diabetes with the Plasmid DNA Platform Clinical Immunology (Orlando, Fla.). Dec, 2013 | Pubmed ID: 24094739 Defective Sphingosine 1-phosphate Receptor 1 (S1P1) Phosphorylation Exacerbates TH17-mediated Autoimmune Neuroinflammation Nature Immunology. Nov, 2013 | Pubmed ID: 24076635 Pathogenic T Helper 1 Cells Reach the Brain Before T Helper 17 Cells, and T Regulatory Cells Suppress Them Albeit Incompletely Acta Neuropathologica. Oct, 2013 | Pubmed ID: 24045898 The Interdependent, Overlapping, and Differential Roles of Type I and II IFNs in the Pathogenesis of Experimental Autoimmune Encephalomyelitis Journal of Immunology (Baltimore, Md. : 1950). Sep, 2013 | Pubmed ID: 23960239 Therapeutic Decisions in Multiple Sclerosis: Moving Beyond Efficacy JAMA Neurology. Oct, 2013 | Pubmed ID: 23921521 The Road Not Taken: Antigen-specific Therapy and Neuroinflammatory Disease JAMA Neurology. Sep, 2013 | Pubmed ID: 23817885 Plasmid-encoded Proinsulin Preserves C-peptide While Specifically Reducing Proinsulin-specific CD8⁺ T Cells in Type 1 Diabetes Science Translational Medicine. Jun, 2013 | Pubmed ID: 23803704 Th17 Cells Induce Th1-polarizing Monocyte-derived Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Aug, 2013 | Pubmed ID: 23794631 CRYAB Modulates the Activation of CD4+ T Cells from Relapsing-remitting Multiple Sclerosis Patients Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2013 | Pubmed ID: 23736536 Interleukin 17F Level and Interferon β Response in Patients with Multiple Sclerosis JAMA Neurology. Aug, 2013 | Pubmed ID: 23732754 Depleting Tumor-specific Tregs at a Single Site Eradicates Disseminated Tumors The Journal of Clinical Investigation. Jun, 2013 | Pubmed ID: 23728179 Expansion of Oligodendrocyte Progenitor Cells Following SIRT1 Inactivation in the Adult Brain Nature Cell Biology. Jun, 2013 | Pubmed ID: 23644469 Serum Autoantibodies to Myelin Peptides Distinguish Acute Disseminated Encephalomyelitis from Relapsing- Remitting Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). Nov, 2013 | Pubmed ID: 23612879 Amyloid Fibrils Composed of Hexameric Peptides Attenuate Neuroinflammation Science Translational Medicine. Apr, 2013 | Pubmed ID: 23552370 Interferon Beta Use and Disability Prevention in Relapsing-remitting Multiple Sclerosis JAMA Neurology. Feb, 2013 | Pubmed ID: 23530268 Progression in Multiple Sclerosis is Associated with Low Endogenous NCAM Journal of Neurochemistry. Jun, 2013 | Pubmed ID: 23495921 A Writing-intensive Course Improves Biology Undergraduates' Perception and Confidence of Their Abilities to Read Scientific Literature and Communicate Science Advances in Physiology Education. Mar, 2013 | Pubmed ID: 23471252 The Gender Gap in Multiple Sclerosis: Intersection of Science and Society JAMA Neurology. May, 2013 | Pubmed ID: 23460044 A Tip Leads Cytotoxic T Cells to the Crime Scene in Neuroinflammation Nature Immunology. Mar, 2013 | Pubmed ID: 23416668 Transient B-cell Depletion with Anti-CD20 in Combination with Proinsulin DNA Vaccine or Oral Insulin: Immunologic Effects and Efficacy in NOD Mice PloS One. 2013 | Pubmed ID: 23405091 Weighing in on Autoimmune Disease: 'Hub-and-spoke' T Cell Traffic in Autoimmunity Nature Medicine. Feb, 2013 | Pubmed ID: 23389609 Inflammatory Cytokines at the Summits of Pathological Signal Cascades in Brain Diseases Science Signaling. Jan, 2013 | Pubmed ID: 23322904 Piet Mondrian's Trees and the Evolution in Understanding Multiple Sclerosis, Charcot Prize Lecture 2011 Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2013 | Pubmed ID: 23303879 Natalizumab: Bench to Bedside and Beyond JAMA Neurology. Feb, 2013 | Pubmed ID: 23128399 Type I Interferons: Beneficial in Th1 and Detrimental in Th17 Autoimmunity Clinical Reviews in Allergy & Immunology. Apr, 2013 | Pubmed ID: 22231516 The Discovery of Natalizumab, a Potent Therapeutic for Multiple Sclerosis The Journal of Cell Biology. Oct, 2012 | Pubmed ID: 23109666 Chaperone Activity of Small Heat Shock Proteins Underlies Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22955287 Reversal of Paralysis and Reduced Inflammation from Peripheral Administration of β-amyloid in TH1 and TH17 Versions of Experimental Autoimmune Encephalomyelitis Science Translational Medicine. Aug, 2012 | Pubmed ID: 22855462 Human Aquaporin 4281-300 is the Immunodominant Linear Determinant in the Context of HLA-DRB1*03:01: Relevance for Diagnosing and Monitoring Patients with Neuromyelitis Optica Archives of Neurology. Sep, 2012 | Pubmed ID: 22751865 Janus-like Opposing Roles of CD47 in Autoimmune Brain Inflammation in Humans and Mice The Journal of Experimental Medicine. Jul, 2012 | Pubmed ID: 22734047 Nostalgia: the Similarities Between Immunological and Neurological Memory Immunological Reviews. Jul, 2012 | Pubmed ID: 22725950 Identification of Naturally Occurring Fatty Acids of the Myelin Sheath That Resolve Neuroinflammation Science Translational Medicine. Jun, 2012 | Pubmed ID: 22674551 Peroxisome Proliferator-activated Receptor (PPAR)α and -γ Regulate IFNγ and IL-17A Production by Human T Cells in a Sex-specific Way Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22647601 The Protective and Therapeutic Function of Small Heat Shock Proteins in Neurological Diseases Frontiers in Immunology. 2012 | Pubmed ID: 22566955 Platelets Provide a Bounty of Potential Targets for Therapy in Multiple Sclerosis Circulation Research. Apr, 2012 | Pubmed ID: 22539752 Lessons Learned at the Intersection of Immunology and Neuroscience The Journal of Clinical Investigation. Apr, 2012 | Pubmed ID: 22466655 Re-engineering of Pathogenic Aquaporin 4-specific Antibodies As Molecular Decoys to Treat Neuromyelitis Optica Annals of Neurology. Mar, 2012 | Pubmed ID: 22451198 Protective Effect of an Elastase Inhibitor in a Neuromyelitis Optica-like Disease Driven by a Peptide of Myelin Oligodendroglial Glycoprotein Multiple Sclerosis (Houndmills, Basingstoke, England). Apr, 2012 | Pubmed ID: 22343184 Therapeutic Effects of Systemic Administration of Chaperone αB-crystallin Associated with Binding Proinflammatory Plasma Proteins The Journal of Biological Chemistry. Mar, 2012 | Pubmed ID: 22308023 Optimization of Current and Future Therapy for Autoimmune Diseases Nature Medicine. Jan, 2012 | Pubmed ID: 22227674 Evolution of MS Lesions to Black Holes Under DNA Vaccine Treatment Journal of Neurology. Jul, 2012 | Pubmed ID: 22222856 Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs from the Nasal Region to the Brain Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2011 | Pubmed ID: 21915101 Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion Circulation. Sep, 2011 | Pubmed ID: 21911812 Impaired Neurosteroid Synthesis in Multiple Sclerosis Brain : a Journal of Neurology. Sep, 2011 | Pubmed ID: 21908875 Tyrosine Kinase Inhibitors Ameliorate Autoimmune Encephalomyelitis in a Mouse Model of Multiple Sclerosis Journal of Clinical Immunology. Dec, 2011 | Pubmed ID: 21847523 Systemic Augmentation of AlphaB-crystallin Provides Therapeutic Benefit Twelve Hours Post-stroke Onset Via Immune Modulation Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21828004 IL-7 Promotes T(H)1 Development and Serum IL-7 Predicts Clinical Response to Interferon-β in Multiple Sclerosis Science Translational Medicine. Jul, 2011 | Pubmed ID: 21795588 1,25-dihydroxyvitamin D(3) Ameliorates Th17 Autoimmunity Via Transcriptional Modulation of Interleukin-17A Molecular and Cellular Biology. Sep, 2011 | Pubmed ID: 21746882 Combining Statins with Interferon β in Multiple Sclerosis: Think Twice, It Might Not Be All Right The Lancet. Neurology. Aug, 2011 | Pubmed ID: 21742557 Human Peptidome Display Nature Biotechnology. Jun, 2011 | Pubmed ID: 21654669 αB-crystallin Improves Murine Cardiac Function and Attenuates Apoptosis in Human Endothelial Cells Exposed to Ischemia-reperfusion The Annals of Thoracic Surgery. Jun, 2011 | Pubmed ID: 21619989 Interferon-β Exacerbates Th17-mediated Inflammatory Disease Trends in Immunology. Jun, 2011 | Pubmed ID: 21530402 Chaperone Activity of α B-crystallin is Responsible for Its Incorrect Assignment As an Autoantigen in Multiple Sclerosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2011 | Pubmed ID: 21357544 Common Variants in P2RY11 Are Associated with Narcolepsy Nature Genetics. Jan, 2011 | Pubmed ID: 21170044 Histamine Regulates Autoreactive T Cell Activation and Adhesiveness in Inflamed Brain Microcirculation Journal of Leukocyte Biology. Feb, 2011 | Pubmed ID: 21071626 Vitamin D, Pregnancy, Breastfeeding, and Postpartum Multiple Sclerosis Relapses Archives of Neurology. Mar, 2011 | Pubmed ID: 21059988 Inverse Vaccination to Silence Immunity to Myelin in Multiple Sclerosis The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Sep, 2010 | Pubmed ID: 21246935 Modulation of Postoperative Cognitive Decline Via Blockade of Inflammatory Cytokines Outside the Brain Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 21098269 Delivery of Myelin Peptides Through the First Line of Defense, Skin, to Counter Autoimmunity in Multiple Sclerosis Annals of Neurology. Nov, 2010 | Pubmed ID: 21031570 Angiotensin II Sustains Brain Inflammation in Mice Via TGF-beta The Journal of Clinical Investigation. Aug, 2010 | Pubmed ID: 20628203 Peroxisome Proliferator-activated Receptor Delta Limits the Expansion of Pathogenic Th Cells During Central Nervous System Autoimmunity The Journal of Experimental Medicine. Aug, 2010 | Pubmed ID: 20624891 Socioeconomic Trends in Hospitalization for Multiple Sclerosis Neuroepidemiology. Aug, 2010 | Pubmed ID: 20551694 Alphab-crystallin is a Target for Adaptive Immune Responses and a Trigger of Innate Responses in Preactive Multiple Sclerosis Lesions Journal of Neuropathology and Experimental Neurology. Jul, 2010 | Pubmed ID: 20535035 Smad7 in T Cells Drives T Helper 1 Responses in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis Brain : a Journal of Neurology. Apr, 2010 | Pubmed ID: 20354004 T Helper Type 1 and 17 Cells Determine Efficacy of Interferon-beta in Multiple Sclerosis and Experimental Encephalomyelitis Nature Medicine. Apr, 2010 | Pubmed ID: 20348925 Inhibitory Role for GABA in Autoimmune Inflammation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133656 IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model Journal of Clinical Immunology. Mar, 2010 | Pubmed ID: 20130970 Interferon-gamma-producing T Cells, Pregnancy, and Postpartum Relapses of Multiple Sclerosis Archives of Neurology. Jan, 2010 | Pubmed ID: 20065129 Mixed Results with Modulation of TH-17 Cells in Human Autoimmune Diseases Nature Immunology. Jan, 2010 | Pubmed ID: 20016509 Autoimmunity Against Fibrinogen Mediates Inflammatory Arthritis in Mice Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 19949094 Mouse Mesenchymal Stem Cells Suppress Antigen-specific TH Cell Immunity Independent of Indoleamine 2,3-dioxygenase 1 (IDO1) Stem Cells and Development. May, 2010 | Pubmed ID: 19886804 Treatment with a Toll-like Receptor Inhibitory GpG Oligonucleotide Delays and Attenuates Lupus Nephritis in NZB/W Mice Autoimmunity. Mar, 2010 | Pubmed ID: 19845477 HMG-CoA Reductase Inhibition Causes Increased Necrosis and Apoptosis in an in Vivo Mouse Glioblastoma Multiforme Model Anticancer Research. Dec, 2009 | Pubmed ID: 20044596 Innate and Adaptive Autoimmunity Directed to the Central Nervous System Neuron. Oct, 2009 | Pubmed ID: 19840554 PPAR-delta Senses and Orchestrates Clearance of Apoptotic Cells to Promote Tolerance Nature Medicine. Nov, 2009 | Pubmed ID: 19838202 Blocking Angiotensin-converting Enzyme Induces Potent Regulatory T Cells and Modulates TH1- and TH17-mediated Autoimmunity Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19706421 Shifting Therapeutic Attention in MS to Osteopontin, Type 1 and Type 2 IFN European Journal of Immunology. Sep, 2009 | Pubmed ID: 19681057 Activation of Kinin Receptor B1 Limits Encephalitogenic T Lymphocyte Recruitment to the Central Nervous System Nature Medicine. Jul, 2009 | Pubmed ID: 19561616 The Gray Aspects of White Matter Disease in Multiple Sclerosis Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19451620 A Molecular Trio in Relapse and Remission in Multiple Sclerosis Nature Reviews. Immunology. Jun, 2009 | Pubmed ID: 19444308 Gaining Entry to an Uninflamed Brain Nature Immunology. May, 2009 | Pubmed ID: 19381137 Systems Biology and Its Application to the Understanding of Neurological Diseases Annals of Neurology. Feb, 2009 | Pubmed ID: 19260029 Enhanced Immune Recognition of Cryptic Glycan Markers in Human Tumors Cancer Research. Mar, 2009 | Pubmed ID: 19223535 Regulation of Different Inflammatory Diseases by Impacting the Mevalonate Pathway Immunology. May, 2009 | Pubmed ID: 19191903 Anaphylaxis to a Self-peptide in the Absence of Mast Cells or Histamine Laboratory Investigation; a Journal of Technical Methods and Pathology. Apr, 2009 | Pubmed ID: 19188909 Improved Efficacy of a Tolerizing DNA Vaccine for Reversal of Hyperglycemia Through Enhancement of Gene Expression and Localization to Intracellular Sites Journal of Immunology (Baltimore, Md. : 1950). Dec, 2008 | Pubmed ID: 19050246 Nuanced Roles of Cytokines in Three Major Human Brain Disorders The Journal of Clinical Investigation. Nov, 2008 | Pubmed ID: 18982162 Differential Regulation of Chemokines by IL-17 in Colonic Epithelial Cells Journal of Immunology (Baltimore, Md. : 1950). Nov, 2008 | Pubmed ID: 18941244 Epitope Spreading to Citrullinated Antigens in Mouse Models of Autoimmune Arthritis and Demyelination Arthritis Research & Therapy. 2008 | Pubmed ID: 18826638 New Targets for Treatment of Multiple Sclerosis Journal of the Neurological Sciences. Nov, 2008 | Pubmed ID: 18768188 A Rush to Judgment on Th17 The Journal of Experimental Medicine. Jul, 2008 | Pubmed ID: 18591407 Thymic Selection Determines Gammadelta T Cell Effector Fate: Antigen-naive Cells Make Interleukin-17 and Antigen-experienced Cells Make Interferon Gamma Immunity. Jul, 2008 | Pubmed ID: 18585064 Failure of Oral Atorvastatin to Modulate a Murine Model of Systemic Lupus Erythematosus Arthritis and Rheumatism. Jul, 2008 | Pubmed ID: 18576356 The Aryl Hydrocarbon Receptor: a Regulator of Th17 and Treg Cell Development in Disease Cell Research. Jun, 2008 | Pubmed ID: 18516065 Type 1 Interferons Cool the Inflamed Brain Immunity. May, 2008 | Pubmed ID: 18482563 Phase 2 Trial of a DNA Vaccine Encoding Myelin Basic Protein for Multiple Sclerosis Annals of Neurology. May, 2008 | Pubmed ID: 18481290 Extensive Fusion of Haematopoietic Cells with Purkinje Neurons in Response to Chronic Inflammation Nature Cell Biology. May, 2008 | Pubmed ID: 18425116 CD4+CD25+ Regulatory T Cells Specific for a Thymus-expressed Antigen Prevent the Development of Anaphylaxis to Self Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18354164 Proteomic Analysis of Active Multiple Sclerosis Lesions Reveals Therapeutic Targets Nature. Feb, 2008 | Pubmed ID: 18278032 Bioluminescence in Vivo Imaging of Autoimmune Encephalomyelitis Predicts Disease Journal of Neuroinflammation. 2008 | Pubmed ID: 18237444 Glia-dependent TGF-beta Signaling, Acting Independently of the TH17 Pathway, is Critical for Initiation of Murine Autoimmune Encephalomyelitis The Journal of Clinical Investigation. Nov, 2007 | Pubmed ID: 17965773 Statins--treatment Option for Central Nervous System Autoimmune Disease? Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Oct, 2007 | Pubmed ID: 17920550 Antigen-specific Therapy of Multiple Sclerosis: the Long-sought Magic Bullet Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Oct, 2007 | Pubmed ID: 17920547 Nanosensor Detection of an Immunoregulatory Tryptophan Influx/kynurenine Efflux Cycle PLoS Biology. Oct, 2007 | Pubmed ID: 17896864 Preemptive HMG-CoA Reductase Inhibition Provides Graft-versus-host Disease Protection by Th-2 Polarization While Sparing Graft-versus-leukemia Activity Blood. Dec, 2007 | Pubmed ID: 17827390 Induction of Antigen-specific Tolerance in Multiple Sclerosis After Immunization with DNA Encoding Myelin Basic Protein in a Randomized, Placebo-controlled Phase 1/2 Trial Archives of Neurology. Oct, 2007 | Pubmed ID: 17698695 Type II Monocytes Modulate T Cell-mediated Central Nervous System Autoimmune Disease Nature Medicine. Aug, 2007 | Pubmed ID: 17676050 Inhibition of HMGcoA Reductase by Atorvastatin Prevents and Reverses MYC-induced Lymphomagenesis Blood. Oct, 2007 | Pubmed ID: 17622571 Protective and Therapeutic Role for AlphaB-crystallin in Autoimmune Demyelination Nature. Jul, 2007 | Pubmed ID: 17568699 A Brief History of T(H)17, the First Major Revision in the T(H)1/T(H)2 Hypothesis of T Cell-mediated Tissue Damage Nature Medicine. Feb, 2007 | Pubmed ID: 17290272 Peroxisome Proliferator-activated Receptor (PPAR)alpha Expression in T Cells Mediates Gender Differences in Development of T Cell-mediated Autoimmunity The Journal of Experimental Medicine. Feb, 2007 | Pubmed ID: 17261635 Heme Oxygenase-1 and Carbon Monoxide Suppress Autoimmune Neuroinflammation The Journal of Clinical Investigation. Feb, 2007 | Pubmed ID: 17256058 Self-antigen Tetramers Discriminate Between Myelin Autoantibodies to Native or Denatured Protein Nature Medicine. Feb, 2007 | Pubmed ID: 17237795 Photogenerated Glycan Arrays Identify Immunogenic Sugar Moieties of Bacillus Anthracis Exosporium Proteomics. Jan, 2007 | Pubmed ID: 17205603 Osteopontin-induced Relapse and Progression of Autoimmune Brain Disease Through Enhanced Survival of Activated T Cells Nature Immunology. Jan, 2007 | Pubmed ID: 17143274 Tolerizing DNA Vaccines for Autoimmune Arthritis Autoimmunity. Dec, 2006 | Pubmed ID: 17178564 Selective Tyrosine Kinase Inhibition by Imatinib Mesylate for the Treatment of Autoimmune Arthritis The Journal of Clinical Investigation. Oct, 2006 | Pubmed ID: 16981009 At Once Harmful and Beneficial: the Dual Properties of NF-kappaB Nature Immunology. Sep, 2006 | Pubmed ID: 16924250 State of the Art. Four Easy Pieces: Interconnections Between Tissue Injury, Intermediary Metabolism, Autoimmunity, and Chronic Degeneration Proceedings of the American Thoracic Society. Aug, 2006 | Pubmed ID: 16921119 Statins in the Treatment of Central Nervous System Autoimmune Disease Journal of Neuroimmunology. Sep, 2006 | Pubmed ID: 16860400 How to Successfully Apply Animal Studies in Experimental Allergic Encephalomyelitis to Research on Multiple Sclerosis Annals of Neurology. Jul, 2006 | Pubmed ID: 16802293 Emerging Therapeutic Targets in Multiple Sclerosis Current Opinion in Neurology. Jun, 2006 | Pubmed ID: 16702832 Nogo in Multiple Sclerosis: Growing Roles of a Growth Inhibitor Journal of the Neurological Sciences. Jun, 2006 | Pubmed ID: 16682057 Statin Therapy and Autoimmune Disease: from Protein Prenylation to Immunomodulation Nature Reviews. Immunology. May, 2006 | Pubmed ID: 16639429 Progressive Multifocal Leukoencephalopathy and Multiple Sclerosis: Lessons from Natalizumab Current Neurology and Neuroscience Reports. May, 2006 | Pubmed ID: 16635435 Immunomodulatory Synergy by Combination of Atorvastatin and Glatiramer Acetate in Treatment of CNS Autoimmunity The Journal of Clinical Investigation. Apr, 2006 | Pubmed ID: 16543951 A Neuropeptide in Immune-mediated Inflammation, Y? Trends in Immunology. Apr, 2006 | Pubmed ID: 16530483 What Went Wrong in the Natalizumab Trials? Lancet (London, England). Mar, 2006 | Pubmed ID: 16517256 Isoprenoids Determine Th1/Th2 Fate in Pathogenic T Cells, Providing a Mechanism of Modulation of Autoimmunity by Atorvastatin The Journal of Experimental Medicine. Feb, 2006 | Pubmed ID: 16476765 Controlling Autoimmunity in Sporadic Inclusion-body Myositis Neurology. Jan, 2006 | Pubmed ID: 16432146 A Key Regulatory Role for Histamine in Experimental Autoimmune Encephalomyelitis: Disease Exacerbation in Histidine Decarboxylase-deficient Mice Journal of Immunology (Baltimore, Md. : 1950). Jan, 2006 | Pubmed ID: 16365391 Lipid Microarrays Identify Key Mediators of Autoimmune Brain Inflammation Nature Medicine. Jan, 2006 | Pubmed ID: 16341241 Drug Insight: Using Statins to Treat Neuroinflammatory Disease Nature Clinical Practice. Neurology. Dec, 2005 | Pubmed ID: 16932506 Antigen-specific Therapies in Multiple Sclerosis: Going Beyond Proteins and Peptides International Reviews of Immunology. Sep-Dec, 2005 | Pubmed ID: 16318989 Treatment of Autoimmune Neuroinflammation with a Synthetic Tryptophan Metabolite Science (New York, N.Y.). Nov, 2005 | Pubmed ID: 16272121 A Suppressive Oligodeoxynucleotide Enhances the Efficacy of Myelin Cocktail/IL-4-tolerizing DNA Vaccination and Treats Autoimmune Disease Journal of Immunology (Baltimore, Md. : 1950). Nov, 2005 | Pubmed ID: 16237121 Therapeutic Considerations for Disease Progression in Multiple Sclerosis: Evidence, Experience, and Future Expectations Archives of Neurology. Oct, 2005 | Pubmed ID: 16216934 Virtues and Pitfalls of EAE for the Development of Therapies for Multiple Sclerosis Trends in Immunology. Nov, 2005 | Pubmed ID: 16153891 אינדוקציה של שיתוק ופציעה מערכת הראייה אצל עכברים מאת T תאים ספציפיים עבור אופטיקה Neuromyelitis Autoantigen Aquaporin-4 Sharon A. Sagan*1,2, Andrés Cruz-Herranz*1, Collin M. Spencer1,2, Peggy P. Ho3, Lawrence Steinman3, Ari J. Green1, Raymond A. Sobel4, Scott S. Zamvil1,2 1Department of Neurology, University of California, 2Program in Immunology, University of California, 3Department of Neurology and Neurological Sciences, Stanford University, 4Department of Pathology, Stanford University JoVE 56185 Immunology and Infection
אינדוקציה של שיתוק ופציעה מערכת הראייה אצל עכברים מאת T תאים ספציפיים עבור אופטיקה Neuromyelitis Autoantigen Aquaporin-4 Sharon A. Sagan*1,2, Andrés Cruz-Herranz*1, Collin M. Spencer1,2, Peggy P. Ho3, Lawrence Steinman3, Ari J. Green1, Raymond A. Sobel4, Scott S. Zamvil1,2 1Department of Neurology, University of California, 2Program in Immunology, University of California, 3Department of Neurology and Neurological Sciences, Stanford University, 4Department of Pathology, Stanford University JoVE 56185 Immunology and Infection
