Leandro Castellano Department of Surgery and Cancer Imperial College London Biography Publications Institution JoVE Articles Leandro Castellano has not added a biography. If you are Leandro Castellano and would like to personalize this page please email our Author Liaison for assistance. Publications The Germline of the Malaria Mosquito Produces Abundant MiRNAs, Endo-siRNAs, PiRNAs and 29-nt Small RNAs BMC Genomics. Feb, 2015 | Pubmed ID: 25766668 Noncoding RNAs and the Control of Hormonal Signaling Via Nuclear Receptor Regulation Journal of Molecular Endocrinology. Oct, 2014 | Pubmed ID: 25062739 5' IsomiR Variation is of Functional and Evolutionary Importance Nucleic Acids Research. Aug, 2014 | Pubmed ID: 25056318 MiR-211 Modulates Gemcitabine Activity Through Downregulation of Ribonucleotide Reductase and Inhibits the Invasive Behavior of Pancreatic Cancer Cells Nucleosides, Nucleotides & Nucleic Acids. 2014 | Pubmed ID: 24940696 Growth Arrest-specific Transcript 5 Associated SnoRNA Levels Are Related to P53 Expression and DNA Damage in Colorectal Cancer PloS One. 2014 | Pubmed ID: 24926850 Quantification of Pancreatic Cancer Proteome and Phosphorylome: Indicates Molecular Events Likely Contributing to Cancer and Activity of Drug Targets PloS One. 2014 | Pubmed ID: 24670416 MiR-15b and MiR-17 Are Tumor-Derived Plasma MicroRNAs Dysregulated in Colorectal Neoplasia Annals of Surgery. Mar, 2014 | Pubmed ID: 24646542 Reduced Dissemination of Circulating Tumor Cells with No-touch Isolation Surgical Technique in Patients with Pancreatic Cancer JAMA Surgery. May, 2014 | Pubmed ID: 24599353 A MicroRNA Meta-signature for Pancreatic Ductal Adenocarcinoma Expert Review of Molecular Diagnostics. Apr, 2014 | Pubmed ID: 24575833 MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression Gastroenterology. Jan, 2014 | Pubmed ID: 24120476 Cell-free DNA for the Detection of Pancreatic, Liver and Upper Gastrointestinal Cancers: Has Progress Been Made? Future Oncology (London, England). Dec, 2013 | Pubmed ID: 24295416 MicroRNA-23b Regulates Cellular Architecture and Impairs Motogenic and Invasive Phenotypes During Cancer Progression Bioarchitecture. Jul-Aug, 2013 | Pubmed ID: 24002530 Downregulation of MicroRNA-515-5p by the Estrogen Receptor Modulates Sphingosine Kinase 1 and Breast Cancer Cell Proliferation Cancer Research. Oct, 2013 | Pubmed ID: 23928990 Emerging Roles of Competing Endogenous RNAs in Cancer: Insights from the Regulation of PTEN Molecular and Cellular Biology. Oct, 2013 | Pubmed ID: 23918803 The P53 MiRNA Interactome and Its Potential Role in the Cancer Clinic Epigenomics. Aug, 2013 | Pubmed ID: 23895654 Circulating Peripheral Blood Mononuclear Cells Exhibit Altered MiRNA Expression Patterns in Pancreatic Cancer Expert Review of Molecular Diagnostics. Jun, 2013 | Pubmed ID: 23782250 Distinct MiRNA Profiles Are Associated with Malignant Transformation of Pancreatic Cystic Tumors Revealing Potential Biomarkers for Clinical Use Expert Review of Molecular Diagnostics. May, 2013 | Pubmed ID: 23638815 MiR-23b Regulates Cytoskeletal Remodeling, Motility and Metastasis by Directly Targeting Multiple Transcripts Nucleic Acids Research. May, 2013 | Pubmed ID: 23580553 Blood-based MiRNAs As Noninvasive Diagnostic and Surrogative Biomarkers in Colorectal Cancer Expert Review of Molecular Diagnostics. Mar, 2013 | Pubmed ID: 23477554 Circulating Molecular Markers in Pancreatic Cancer: Ready for Clinical Use? Future Oncology (London, England). Feb, 2013 | Pubmed ID: 23414463 Deep Sequencing of Small RNAs Identifies Canonical and Non-canonical MiRNA and Endogenous SiRNAs in Mammalian Somatic Tissues Nucleic Acids Research. Mar, 2013 | Pubmed ID: 23325850 Altered Expression of the MiRNA Processing Endoribonuclease Dicer Has Prognostic Significance in Human Cancers Expert Review of Anticancer Therapy. Jan, 2013 | Pubmed ID: 23259424 Towards a Clinical Use of MiRNAs in Pancreatic Cancer Biopsies Expert Review of Molecular Diagnostics. Jan, 2013 | Pubmed ID: 23256701 Defining a Prognostic Molecular Profile for Ductal Adenocarcinoma of the Pancreas Highlights Known Key Signaling Pathways Expert Review of Anticancer Therapy. Oct, 2012 | Pubmed ID: 23176615 Breast Cancer Treatment and Adverse Cardiac Events: What Are the Molecular Mechanisms? Cardiology. 2012 | Pubmed ID: 22907032 Loss of MiR-126 is Crucial to Pancreatic Cancer Progression Expert Review of Anticancer Therapy. Jul, 2012 | Pubmed ID: 22845403 The Role of MiR-10b in Metastatic Pancreatic Ductal Adenocarcinoma Surgery. Nov, 2012 | Pubmed ID: 22682079 Retinoblastoma Protein Determines Aggressiveness in Triple-negative Breast Cancer Expert Review of Anticancer Therapy. May, 2012 | Pubmed ID: 22594893 Transcriptome-level Microarray Expression Profiling Implicates IGF-1 and Wnt Signalling Dysregulation in the Pathogenesis of Thyroid-associated Orbitopathy Journal of Clinical Pathology. Jul, 2012 | Pubmed ID: 22554965 MiRNAs in Breast Cancer: Ready for Real Time? Pharmacogenomics. Apr, 2012 | Pubmed ID: 22515613 The Clinico-pathologic Role of MicroRNAs MiR-9 and MiR-151-5p in Breast Cancer Metastasis Molecular Diagnosis & Therapy. Jun, 2012 | Pubmed ID: 22489664 MicroRNAs Targeting Oncogenes Are Down-regulated in Pancreatic Malignant Transformation from Benign Tumors PloS One. 2012 | Pubmed ID: 22384141 Integrated Analysis of MiRNA and MRNA Profiles Enables Target Acquisition in Human Cancers Expert Review of Anticancer Therapy. Mar, 2012 | Pubmed ID: 22369323 MicroRNAs As Markers of Survival and Chemoresistance in Pancreatic Ductal Adenocarcinoma Expert Review of Anticancer Therapy. Dec, 2011 | Pubmed ID: 22117151 Determination of Cut-offs for Circulating Tumor Cell Measurement in Metastatic Cancer Expert Review of Anticancer Therapy. Sep, 2011 | Pubmed ID: 21929309 Kinome Screening for Regulators of the Estrogen Receptor Identifies LMTK3 As a New Therapeutic Target in Breast Cancer Nature Medicine. Jun, 2011 | Pubmed ID: 21602804 No Evidence for a Polyomavirus Association or Aetiology in AIDS-associated Nonsmall Cell Lung Cancer AIDS (London, England). May, 2010 | Pubmed ID: 20400884 No Evidence for a Viral Association or Aetiology in Pancreatic Cancer Molecular Immunology. Jan, 2010 | Pubmed ID: 19932507 The Estrogen Receptor-alpha-induced MicroRNA Signature Regulates Itself and Its Transcriptional Response Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19706389 CK1delta Modulates the Transcriptional Activity of ERalpha Via AIB1 in an Estrogen-dependent Manner and Regulates ERalpha-AIB1 Interactions Nucleic Acids Research. May, 2009 | Pubmed ID: 19339517 Bendamustine As a Model for the Activity of Alkylating Agents Future Oncology (London, England). Jun, 2008 | Pubmed ID: 18518757 Quantitative Technologies Establish a Novel MicroRNA Profile of Chronic Lymphocytic Leukemia Blood. Jun, 2007 | Pubmed ID: 17327404 Mammosphere Dannelse Assay fra human brystkræft væv og cellelinier Ylenia Lombardo*1, Alexander de Giorgio*1, Charles R. Coombes1, Justin Stebbing1, Leandro Castellano1 1Department of Surgery and Cancer, Imperial College London Medicine
Mammosphere Dannelse Assay fra human brystkræft væv og cellelinier Ylenia Lombardo*1, Alexander de Giorgio*1, Charles R. Coombes1, Justin Stebbing1, Leandro Castellano1 1Department of Surgery and Cancer, Imperial College London Medicine