Leda Raptis Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Medicine Queen's University, Kingston Biography Publications Institution JoVE Articles Leda Raptis has not added a biography. If you are Leda Raptis and would like to personalize this page please email our Author Liaison for assistance. Publications Regulation of HC11 Mouse Breast Epithelial Cell Differentiation by the E-cadherin/Rac Axis Experimental Cell Research. 12, 2017 | Pubmed ID: 29031557 Differential Effects of Polyoma Virus Middle Tumor Antigen Mutants Upon Gap Junctional, Intercellular Communication Experimental Cell Research. Aug, 2015 | Pubmed ID: 26187405 Preclinical Characterization of Signal Transducer and Activator of Transcription 3 Small Molecule Inhibitors for Primary and Metastatic Brain Cancer Therapy The Journal of Pharmacology and Experimental Therapeutics. Jun, 2014 | Pubmed ID: 24696041 Stat3 and Gap Junctions in Normal and Lung Cancer Cells Cancers. 2014 | Pubmed ID: 24670366 Engaged for Survival: From Cadherin Ligation to STAT3 Activation JAK-STAT. Oct, 2013 | Pubmed ID: 24470979 Effects of SRC and STAT3 Upon Gap Junctional, Intercellular Communication in Lung Cancer Lines Anticancer Research. Oct, 2013 | Pubmed ID: 24123009 Automated Quantitative Analysis of P53, Cyclin D1, Ki67 and PERK Expression in Breast Carcinoma Does Not Differ from Expert Pathologist Scoring and Correlates with Clinico-Pathological Characteristics Cancers. 2012 | Pubmed ID: 24213463 Stat3 is a Positive Regulator of Gap Junctional Intercellular Communication in Cultured, Human Lung Carcinoma Cells BMC Cancer. 2012 | Pubmed ID: 23244248 Mind the Gap; Regulation of Gap Junctional, Intercellular Communication by the SRC Oncogene Product and Its Effectors Anticancer Research. Oct, 2012 | Pubmed ID: 23060544 The R(h)oads to Stat3: Stat3 Activation by the Rho GTPases Experimental Cell Research. Aug, 2011 | Pubmed ID: 21619876 Characterization of the Oncogenic Activity of the Novel TRIM59 Gene in Mouse Cancer Models Molecular Cancer Therapeutics. Jul, 2011 | Pubmed ID: 21593385 EIF2{alpha} Kinase PKR Modulates the Hypoxic Response by Stat3-dependent Transcriptional Suppression of HIF-1{alpha} Cancer Research. Oct, 2010 | Pubmed ID: 20924113 Doubles Game: Src-Stat3 Versus P53-PTEN in Cellular Migration and Invasion Molecular and Cellular Biology. Nov, 2010 | Pubmed ID: 20733006 Housekeeping Genes; Expression Levels May Change with Density of Cultured Cells Journal of Immunological Methods. Apr, 2010 | Pubmed ID: 20171969 The Simian Virus 40 Large Tumor Antigen Activates CSrc and Requires CSrc for Full Neoplastic Transformation Anticancer Research. Jan, 2010 | Pubmed ID: 20150616 Activated Rac1 Requires Gp130 for Stat3 Activation, Cell Proliferation and Migration Experimental Cell Research. Mar, 2010 | Pubmed ID: 19852956 Beyond Structure, to Survival: Activation of Stat3 by Cadherin Engagement Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Dec, 2009 | Pubmed ID: 19935869 Cadherin-cadherin Engagement Promotes Cell Survival Via Rac1/Cdc42 and Signal Transducer and Activator of Transcription-3 Molecular Cancer Research : MCR. Aug, 2009 | Pubmed ID: 19671682 Stat3 Activity is Required for Gap Junctional Permeability in Normal Rat Liver Epithelial Cells DNA and Cell Biology. Jul, 2009 | Pubmed ID: 19456249 Electroporation of Adherent Cells in Situ for the Study of Signal Transduction and Gap Junctional Communication Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370198 Electrode Assemblies Used for Electroporation of Cultured Cells Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370190 Synthesis, Characterization and Stat3 Inhibitory Properties of the Prototypical Platinum(IV) Anticancer Drug, [PtCl3(NO2)(NH3)2] (CPA-7) Inorganic Chemistry. Apr, 2008 | Pubmed ID: 18269242 Examination of Gap Junctional, Intercellular Communication by in Situ Electroporation on Two Co-planar Indium-tin Oxide Electrodes Molecular Oncology. Sep, 2007 | Pubmed ID: 19383296 Differential Effects of C-Ras Upon Transformation, Adipocytic Differentiation, and Apoptosis Mediated by the Simian Virus 40 Large Tumor Antigen Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Feb, 2007 | Pubmed ID: 17464343 Differential Effects of Stat3 Inhibition in Sparse Vs Confluent Normal and Breast Cancer Cells Cancer Letters. Oct, 2006 | Pubmed ID: 16377083 Stat3 is Required for Full Neoplastic Transformation by the Simian Virus 40 Large Tumor Antigen Molecular Biology of the Cell. Aug, 2005 | Pubmed ID: 15917293 Adenovirus-5 E1A Suppresses Differentiation of 3T3 L1 Preadipocytes at Lower Levels Than Required for Induction of Apoptosis Molecular Carcinogenesis. May, 2005 | Pubmed ID: 15768386 Cell-to-cell Adhesion Modulates Stat3 Activity in Normal and Breast Carcinoma Cells Oncogene. Apr, 2004 | Pubmed ID: 15007380 In Situ Electroporation of Radioactive Compounds into Adherent Cells DNA and Cell Biology. May, 2003 | Pubmed ID: 12941161 In Situ Electroporation of Large Numbers of Cells Using Minimal Volumes of Material Analytical Biochemistry. Jun, 2003 | Pubmed ID: 12729610 Gap Junctional Intercellular Communication in Cells Isolated from Urethane-induced Tumors in A/J Mice DNA and Cell Biology. Jan, 2003 | Pubmed ID: 12590735 Growth and Isotopic Labelling of Adherent Cells in Small Volumes of Medium Journal of Virological Methods. Mar, 2002 | Pubmed ID: 11849699 The Role of Hsp90N, a New Member of the Hsp90 Family, in Signal Transduction and Neoplastic Transformation The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11751906 Differentiation of Mouse Breast Epithelial HC11 and EpH4 Cells Mulu Geletu*1,2, Victoria Hoskin*1, Blerta Starova*1,3, Maximilian Niit1,4, Hanad Adan1, Bruce Elliott1, Patrick Gunning2, Leda Raptis1 1Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Medicine, Queen's University, Kingston, 2Department of Chemical and Physical Sciences, University of Toronto, Mississauga, 3Department of Laboratory Medicine, Brampton Civic Hospital Campus, William Osler Health System, 4Latner Thoracic Surgery Research Laboratories JoVE 60147 Cancer Research A Functional Assay for Gap Junctional Examination; Electroporation of Adherent Cells on Indium-Tin Oxide Mulu Geletu1, Stephanie Guy1, Kevin Firth2, Leda Raptis1 1Department of Microbiology and Immunology and Department of Pathology, Queen's University, 2Ask Science Products Inc. JoVE 51710 Biology
Differentiation of Mouse Breast Epithelial HC11 and EpH4 Cells Mulu Geletu*1,2, Victoria Hoskin*1, Blerta Starova*1,3, Maximilian Niit1,4, Hanad Adan1, Bruce Elliott1, Patrick Gunning2, Leda Raptis1 1Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Medicine, Queen's University, Kingston, 2Department of Chemical and Physical Sciences, University of Toronto, Mississauga, 3Department of Laboratory Medicine, Brampton Civic Hospital Campus, William Osler Health System, 4Latner Thoracic Surgery Research Laboratories JoVE 60147 Cancer Research
A Functional Assay for Gap Junctional Examination; Electroporation of Adherent Cells on Indium-Tin Oxide Mulu Geletu1, Stephanie Guy1, Kevin Firth2, Leda Raptis1 1Department of Microbiology and Immunology and Department of Pathology, Queen's University, 2Ask Science Products Inc. JoVE 51710 Biology
