Lena Serghides

Publications

• Chronic HIV Infection Impairs Nonopsonic Phagocytosis of Malaria Parasites
  Journal of Acquired Immune Deficiency Syndromes (1999). Feb, 2015  |   Pubmed ID: 25415293
• HIV Protease Inhibitor Use During Pregnancy is Associated with Decreased Progesterone Levels, Suggesting a Potential Mechanism Contributing to Fetal Growth Restriction
  The Journal of Infectious Diseases. Jan, 2015  |   Pubmed ID: 25030058
• PPARγ Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria
  PLoS Pathogens. Mar, 2014  |   Pubmed ID: 24603727
• Murine Plasmodium Chabaudi Malaria Increases Mucosal Immune Activation and the Expression of Putative HIV Susceptibility Markers in the Gut and Genital Mucosae
  Journal of Acquired Immune Deficiency Syndromes (1999). Apr, 2014  |   Pubmed ID: 24256632
• The Importance of Motherhood in HIV-positive Women of Reproductive Age in Ontario, Canada
  AIDS Care. 2014  |   Pubmed ID: 24206065
• Functional Roles for C5a and C5aR but Not C5L2 in the Pathogenesis of Human and Experimental Cerebral Malaria
  Infection and Immunity. Jan, 2014  |   Pubmed ID: 24191300
• HIV Infection Deregulates Tim-3 Expression on Innate Cells: Combination Antiretroviral Therapy Results in Partial Restoration
  Journal of Acquired Immune Deficiency Syndromes (1999). Jun, 2013  |   Pubmed ID: 23314411
• HIV Infection Deregulates Innate Immunity to Malaria Despite Combination Antiretroviral Therapy
  AIDS (London, England). Jan, 2013  |   Pubmed ID: 23291537
• A Phase I Clinical Study of Inhaled Nitric Oxide in Healthy Adults
  Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Jul, 2012  |   Pubmed ID: 22520076
• The Case for the Use of PPARγ Agonists As an Adjunctive Therapy for Cerebral Malaria
  PPAR Research. 2012  |   Pubmed ID: 21772838
• Inhaled Nitric Oxide Reduces Endothelial Activation and Parasite Accumulation in the Brain, and Enhances Survival in Experimental Cerebral Malaria
  PloS One. 2011  |   Pubmed ID: 22110737
• Nitric Oxide for the Adjunctive Treatment of Severe Malaria: Hypothesis and Rationale
  Medical Hypotheses. Sep, 2011  |   Pubmed ID: 21745716
• Caspase-12 Dampens the Immune Response to Malaria Independently of the Inflammasome by Targeting NF-kappaB Signaling
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010  |   Pubmed ID: 20876354
• Cerebral Malaria: Human Versus Mouse Studies
  Trends in Parasitology. Jun, 2010  |   Pubmed ID: 20382077
• Use of Peroxisome Proliferator-activated Receptor Gamma Agonists As Adjunctive Treatment for Plasmodium Falciparum Malaria: a Randomized, Double-blind, Placebo-controlled Trial
  Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Sep, 2009  |   Pubmed ID: 19673614
• Rosiglitazone Modulates the Innate Immune Response to Plasmodium Falciparum Infection and Improves Outcome in Experimental Cerebral Malaria
  The Journal of Infectious Diseases. May, 2009  |   Pubmed ID: 19392627
• C5a Enhances Dysregulated Inflammatory and Angiogenic Responses to Malaria in Vitro: Potential Implications for Placental Malaria
  PloS One. 2009  |   Pubmed ID: 19308263
• C5 Deficiency and C5a or C5aR Blockade Protects Against Cerebral Malaria
  The Journal of Experimental Medicine. May, 2008  |   Pubmed ID: 18426986
• Pyruvate Kinase Deficiency and Malaria
  The New England Journal of Medicine. Apr, 2008  |   Pubmed ID: 18420493
• HIV Impairs Opsonic Phagocytic Clearance of Pregnancy-associated Malaria Parasites
  PLoS Medicine. May, 2007  |   Pubmed ID: 17535103
• Disruption of CD36 Impairs Cytokine Response to Plasmodium Falciparum Glycosylphosphatidylinositol and Confers Susceptibility to Severe and Fatal Malaria in Vivo
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2007  |   Pubmed ID: 17339496
• Disruption of JNK2 Decreases the Cytokine Response to Plasmodium Falciparum Glycosylphosphatidylinositol in Vitro and Confers Protection in a Cerebral Malaria Model
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2006  |   Pubmed ID: 17056565
• Approaches to Studying Costimulation of Human Antiviral T Cell Responses: Prospects for Immunotherapeutic Vaccines
  Immunologic Research. 2006  |   Pubmed ID: 17003516
• Placental Chondroitin Sulfate A-binding Malarial Isolates Evade Innate Phagocytic Clearance
  The Journal of Infectious Diseases. Jul, 2006  |   Pubmed ID: 16741892
• Evaluation of OX40 Ligand As a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2005  |   Pubmed ID: 16272289
• Nonopsonic Phagocytosis of Erythrocytes Infected with Ring-stage Plasmodium Falciparum
  Infection and Immunity. Apr, 2005  |   Pubmed ID: 15784606
• Peroxisome Proliferator-activated Receptor Gamma and Retinoid X Receptor Agonists Have Minimal Effects on the Interaction of Endothelial Cells with Plasmodium Falciparum-infected Erythrocytes
  Infection and Immunity. Feb, 2005  |   Pubmed ID: 15664966
• CD36 Mediates the Phagocytosis of Plasmodium Falciparum-infected Erythrocytes by Rodent Macrophages
  The Journal of Infectious Diseases. Jan, 2004  |   Pubmed ID: 14722884
• Effect of HIV-1 Antiretroviral Drugs on Cytoadherence and Phagocytic Clearance of Plasmodium Falciparum-parasitised Erythrocytes
  Lancet (London, England). Sep, 2003  |   Pubmed ID: 14522535
• CD36 and Malaria: Friends or Foes?
  Trends in Parasitology. Oct, 2003  |   Pubmed ID: 14519584
• CD36-mediated Nonopsonic Phagocytosis of Erythrocytes Infected with Stage I and IIA Gametocytes of Plasmodium Falciparum
  Infection and Immunity. Jan, 2003  |   Pubmed ID: 12496189
• Innate Immunity to Malaria Caused by Plasmodium Falciparum
  Clinical and Investigative Medicine. Médecine Clinique Et Experimentale. Dec, 2002  |   Pubmed ID: 12516999
• Mechanism of Protection Induced by Vitamin A in Falciparum Malaria
  Lancet (London, England). Apr, 2002  |   Pubmed ID: 11978340
• CD36 Deficiency Induced by Antiretroviral Therapy
  AIDS (London, England). Feb, 2002  |   Pubmed ID: 11834946