Leonard K. Kaczmarek

Publications

• Clinical Whole-genome Sequencing in Severe Early-onset Epilepsy Reveals New Genes and Improves Molecular Diagnosis
  Human Molecular Genetics. Jan, 2014  |   Pubmed ID: 24463883
• The Contribution of TWIK-1 Channels to Astrocyte K(+) Current is Limited by Retention in Intracellular Compartments
  Frontiers in Cellular Neuroscience. 2013  |   Pubmed ID: 24368895
• Slack, Slick and Sodium-Activated Potassium Channels
  ISRN Neuroscience. Apr, 2013  |   Pubmed ID: 24319675
• Expression of Kv1.3 Potassium Channels Regulates Density of Cortical Interneurons
  Developmental Neurobiology. Nov, 2013  |   Pubmed ID: 23821603
• A Sodium-activated Potassium Channel Supports High-frequency Firing and Reduces Energetic Costs During Rapid Modulations of Action Potential Amplitude
  Journal of Neurophysiology. Apr, 2013  |   Pubmed ID: 23324315
• Un Mode évolutif Conservé De La Modulation Des Canaux K⁺ Shaw-comme
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2013  |   Pubmed ID: 23233530
• Regulation of Neuronal Excitability by Interaction of Fragile X Mental Retardation Protein with Slack Potassium Channels
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2012  |   Pubmed ID: 23115170
• De Novo Gain-of-function KCNT1 Channel Mutations Cause Malignant Migrating Partial Seizures of Infancy
  Nature Genetics. Nov, 2012  |   Pubmed ID: 23086397
• Gradients and Modulation of K(+) Channels Optimize Temporal Accuracy in Networks of Auditory Neurons
  PLoS Computational Biology. 2012  |   Pubmed ID: 22438799
• Bcl-xL Réglemente énergétique Mitochondrial En Stabilisant La Membrane Interne Potentielle
  The Journal of Cell Biology. Oct, 2011  |   Pubmed ID: 21987637
• Potassium Channel Modulation and Auditory Processing
  Hearing Research. Sep, 2011  |   Pubmed ID: 21414395
• Fragile X Mental Retardation Protein is Required for Rapid Experience-dependent Regulation of the Potassium Channel Kv3.1b
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2010  |   Pubmed ID: 20685971
• A Less Flexible BK Channel Opens More Easily
  Neuron. Jun, 2010  |   Pubmed ID: 20620867
• Localization of Kv1.3 Channels in Presynaptic Terminals of Brainstem Auditory Neurons
  The Journal of Comparative Neurology. Aug, 2010  |   Pubmed ID: 20575068
• Fragile X Mental Retardation Protein Controls Gating of the Sodium-activated Potassium Channel Slack
  Nature Neuroscience. Jul, 2010  |   Pubmed ID: 20512134
• Controlling Auditory Excitability: the Benefits of a Cultured Environment
  The Journal of Physiology. May, 2010  |   Pubmed ID: 20436041
• The Slack Sodium-activated Potassium Channel Provides a Major Outward Current in Olfactory Neurons of Kv1.3-/- Super-smeller Mice
  Journal of Neurophysiology. Jun, 2010  |   Pubmed ID: 20393063
• Kv1.3 is the Exclusive Voltage-gated K+ Channel of Platelets and Megakaryocytes: Roles in Membrane Potential, Ca2+ Signalling and Platelet Count
  The Journal of Physiology. May, 2010  |   Pubmed ID: 20308249
• Use of Optical Biosensors to Detect Modulation of Slack Potassium Channels by G Protein-coupled Receptors
  Journal of Receptor and Signal Transduction Research. 2009  |   Pubmed ID: 19640220
• The N-terminal Domain of Slack Determines the Formation and Trafficking of Slick/Slack Heteromeric Sodium-activated Potassium Channels
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2009  |   Pubmed ID: 19403831
• Na+-mediated Coupling Between AMPA Receptors and KNa Channels Shapes Synaptic Transmission
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008  |   Pubmed ID: 19095801
• Amino-termini Isoforms of the Slack K+ Channel, Regulated by Alternative Promoters, Differentially Modulate Rhythmic Firing and Adaptation
  The Journal of Physiology. Nov, 2008  |   Pubmed ID: 18787033
• Protein Kinase C Modulates Inactivation of Kv3.3 Channels
  The Journal of Biological Chemistry. Aug, 2008  |   Pubmed ID: 18539595
• PKC Induite Par Le Trafic Intracellulaire De Ca (V) 2 Précède Son Recrutement Rapide De La Membrane Plasmique
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2008  |   Pubmed ID: 18322103
• Repetitive Firing Triggers Clustering of Kv2.1 Potassium Channels in Aplysia Neurons
  The Journal of Biological Chemistry. Apr, 2008  |   Pubmed ID: 18276591
• Inhibiteur De La Bcl-xL ABT-737 Révèle Un Double Rôle Pour Bcl-xL Dans La Transmission Synaptique
  Journal of Neurophysiology. Mar, 2008  |   Pubmed ID: 18160428
• Comparative Effects of Sodium Pyrithione Evoked Intracellular Calcium Elevation in Rodent and Primate Ventral Horn Motor Neurons
  Biochemical and Biophysical Research Communications. Feb, 2008  |   Pubmed ID: 18053804
• Sodium-dependent Potassium Channels of a Slack-like Subtype Contribute to the Slow Afterhyperpolarization in Lamprey Spinal Neurons
  The Journal of Physiology. Nov, 2007  |   Pubmed ID: 17884929
• Slack and Slick K(Na) Channels Regulate the Accuracy of Timing of Auditory Neurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2007  |   Pubmed ID: 17344399
• Functional Analysis of a Novel Potassium Channel (KCNA1) Mutation in Hereditary Myokymia
  Neurogenetics. Apr, 2007  |   Pubmed ID: 17136396
• Non-conducting Functions of Voltage-gated Ion Channels
  Nature Reviews. Neuroscience. Oct, 2006  |   Pubmed ID: 16988652
• A Store-operated Ca(2+) Influx Pathway in the Bag Cell Neurons of Aplysia
  Journal of Neurophysiology. Nov, 2006  |   Pubmed ID: 16885525
• Pharmacological Activation and Inhibition of Slack (Slo2.2) Channels
  Neuropharmacology. Sep, 2006  |   Pubmed ID: 16876206
• Opposite Regulation of Slick and Slack K+ Channels by Neuromodulators
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2006  |   Pubmed ID: 16687497
• Modulation of Kv3.1b Potassium Channel Phosphorylation in Auditory Neurons by Conventional and Novel Protein Kinase C Isozymes
  The Journal of Biological Chemistry. Jun, 2006  |   Pubmed ID: 16595659
• Policing the Ball: a New Potassium Channel Subunit Determines Inactivation Rate
  Neuron. Mar, 2006  |   Pubmed ID: 16504937
• Retraction
  Science (New York, N.Y.). Dec, 2005  |   Pubmed ID: 16373558
• Acoustic Environment Determines Phosphorylation State of the Kv3.1 Potassium Channel in Auditory Neurons
  Nature Neuroscience. Oct, 2005  |   Pubmed ID: 16136041
• Association/dissociation of a Channel-kinase Complex Underlies State-dependent Modulation
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2005  |   Pubmed ID: 16135761
• Actions De BAX Sur L'activité Mitochondriale Et Sur La Transmission Synaptique
  Antioxidants & Redox Signaling. Sep-Oct, 2005  |   Pubmed ID: 16115013
• Regulation of the Timing of MNTB Neurons by Short-term and Long-term Modulation of Potassium Channels
  Hearing Research. Aug, 2005  |   Pubmed ID: 16081004
• For K+ Channels, Na+ is the New Ca2+
  Trends in Neurosciences. Aug, 2005  |   Pubmed ID: 15979166
• Localization of the Na+-activated K+ Channel Slick in the Rat Central Nervous System
  The Journal of Comparative Neurology. Mar, 2005  |   Pubmed ID: 15717307
• Requirement of Voltage-gated Calcium Channel Beta4 Subunit for T Lymphocyte Functions
  Science (New York, N.Y.). Jan, 2005  |   Pubmed ID: 15637280
• Exposition à L'hypoxie Induit Rapidement L'activité Mitochondriale Dans Une Synapse Vie
  The Journal of Biological Chemistry. Feb, 2005  |   Pubmed ID: 15561723
• Aminoglycosides Block the Kv3.1 Potassium Channel and Reduce the Ability of Inferior Colliculus Neurons to Fire at High Frequencies
  Journal of Neurobiology. Mar, 2005  |   Pubmed ID: 15547932
• The Appearance of a Protein Kinase A-regulated Splice Isoform of Slo is Associated with the Maturation of Neurons That Control Reproductive Behavior
  The Journal of Biological Chemistry. Dec, 2004  |   Pubmed ID: 15375169
• Pro-apoptotique N-tronqué De Protéine BCL-xL Active Des Canaux Mitochondriales Endogènes Dans Les Terminaisons Synaptiques Vivant
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004  |   Pubmed ID: 15342906
• Activation of a Calcium Entry Pathway by Sodium Pyrithione in the Bag Cell Neurons of Aplysia
  Journal of Neurobiology. Sep, 2004  |   Pubmed ID: 15307146
• Loss of Kv3.1 Tonotopicity and Alterations in CAMP Response Element-binding Protein Signaling in Central Auditory Neurons of Hearing Impaired Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2004  |   Pubmed ID: 14985434
• The Voltage-gated Potassium Channel Kv1.3 Regulates Peripheral Insulin Sensitivity
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004  |   Pubmed ID: 14981264
• Slick (Slo2.1), a Rapidly-gating Sodium-activated Potassium Channel Inhibited by ATP
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2003  |   Pubmed ID: 14684870
• Functional Specialization of Male and Female Vocal Motoneurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2003  |   Pubmed ID: 14684859
• How to Make a Relationship Last: Release Sites with Different Levels of Commitment
  Neuron. Sep, 2003  |   Pubmed ID: 14527428
• Modulation De La Transmission Synaptique De La Protéine BCL-2 Famille Protéine BCL-xL
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2003  |   Pubmed ID: 12968005
• Compensatory Anion Currents in Kv1.3 Channel-deficient Thymocytes
  The Journal of Biological Chemistry. Oct, 2003  |   Pubmed ID: 12878608
• Modulation De La Fonction Mitochondriale Par Pools Zn2 + Endogènes
  Proceedings of the National Academy of Sciences of the United States of America. May, 2003  |   Pubmed ID: 12724524
• BAK Modifie L'excitabilité Neuronale Et Permet De Passer D'une Fonction Anti - Pro Mort Durant Le Développement Postnatal
  Developmental Cell. Apr, 2003  |   Pubmed ID: 12689595
• Modulation of the Kv3.1b Potassium Channel Isoform Adjusts the Fidelity of the Firing Pattern of Auditory Neurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2003  |   Pubmed ID: 12598601
• Act Locally: New Ways of Regulating Voltage-gated Ion Channels
  Molecular Interventions. Jul, 2002  |   Pubmed ID: 14993392
• Prolonged Activation of Ca2+-activated K+ Current Contributes to the Long-lasting Refractory Period of Aplysia Bag Cell Neurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2002  |   Pubmed ID: 12451114
• Localization of the Slack Potassium Channel in the Rat Central Nervous System
  The Journal of Comparative Neurology. Dec, 2002  |   Pubmed ID: 12442315
• HSV-1 Helper Virus 5dl1.2 Suppresses Sodium Currents in Amplicon-transduced Neurons
  Journal of Neurophysiology. Apr, 2002  |   Pubmed ID: 11929932
• Endogenous Parathyroid Hormone-related Protein Functions As a Neuroprotective Agent
  Brain Research. Mar, 2002  |   Pubmed ID: 11879796
• Protein Kinase Modulation of a Neuronal Cation Channel Requires Protein-protein Interactions Mediated by an Src Homology 3 Domain
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002  |   Pubmed ID: 11756482