Lesley Mathews Griner Oncology Drug Discovery: Molecular Pharmacology Novartis Institutes for Biomedical Research Biography Publications Institution JoVE Articles Lesley Mathews Griner has not added a biography. If you are Lesley Mathews Griner and would like to personalize this page please email our Author Liaison for assistance. Publications Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF Cancer Research. Mar, 2018 | Pubmed ID: 29343524 Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers Journal of Medicinal Chemistry. Jun, 2017 | Pubmed ID: 28557458 Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening Lesley Mathews Griner1, Kalyani Gampa1, Toan Do2, Huyen Nguyen2, David Farley2, Christopher J. Hogan2, Douglas S. Auld2, Serena J. Silver1 1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research JoVE 57476 Cancer Research
Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening Lesley Mathews Griner1, Kalyani Gampa1, Toan Do2, Huyen Nguyen2, David Farley2, Christopher J. Hogan2, Douglas S. Auld2, Serena J. Silver1 1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research JoVE 57476 Cancer Research
