Liang Deng Merck Research Laboratory Merck & Co., Inc Biography Publications Institution JoVE Articles Liang Deng has not added a biography. If you are Liang Deng and would like to personalize this page please email our Author Liaison for assistance. Publications [Effects of Exogenous Transforming Growth Factor-β3 on the Activities of Its Promoter and CAMP-responsive Element Binding Protein-1 in Rat Hepatic Stellate Cell] Zhonghua Yi Xue Za Zhi. Sep, 2011 | Pubmed ID: 22321755 [Components of Myrsinane-type Diterpenes from Euphorbia Prolifera] Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. Jul, 2011 | Pubmed ID: 21845750 Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells Via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent Pathway Journal of Virology. Oct, 2011 | Pubmed ID: 21835795 Effects of P-CREB-1 on Transforming Growth Factor-β3 Auto-regulation in Hepatic Stellate Cells Journal of Cellular Biochemistry. Apr, 2011 | Pubmed ID: 21308733 Stabilization of 3:1 Site-differentiated Cubane-type Clusters in the [Fe(4)S(4)](1+) Core Oxidation State by Tertiary Phosphine Ligation: Synthesis, Core Structural Diversity, and S = 1/2 Ground States Inorganic Chemistry. Dec, 2010 | Pubmed ID: 21038882 [Preliminary Study on Mechanism of Therapeutic Effect of Huganjiexian Decoction on Hepatic Fibrosis] Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology. Mar, 2010 | Pubmed ID: 20380795 MRNA Stability and Antibody Production in CHO Cells: Improvement Through Gene Optimization Biotechnology Journal. Apr, 2010 | Pubmed ID: 20222103 The Modular Nature of All-ferrous Edge-bridged Double Cubanes Inorganic Chemistry. Feb, 2010 | Pubmed ID: 20073485 Cubane-type Co4S4 Clusters: Synthesis, Redox Series, and Magnetic Ground States Journal of the American Chemical Society. Aug, 2009 | Pubmed ID: 19722678 Zirconocene-mediated Ligand-switched Selective Cleavage of Active and Inert Carbon-carbon Bonds in Allylcyclopropanes Chemical Communications (Cambridge, England). Aug, 2009 | Pubmed ID: 19597610 Cleavage of Ni-(mu(2)-S)-Ni Bridges in Dinuclear Nickel(II) Dithiolate Pincer Complexes and Related Reactions Inorganic Chemistry. Jul, 2009 | Pubmed ID: 19459662 Mössbauer, Electron Paramagnetic Resonance, and Theoretical Studies of a Carbene-based All-ferrous Fe4S4 Cluster: Electronic Origin and Structural Identification of the Unique Spectroscopic Site Inorganic Chemistry. Apr, 2009 | Pubmed ID: 19326927 Vaccinia Virus Subverts a Mitochondrial Antiviral Signaling Protein-dependent Innate Immune Response in Keratinocytes Through Its Double-stranded RNA Binding Protein, E3 Journal of Virology. Nov, 2008 | Pubmed ID: 18715932 Stabilization of Fully Reduced Iron-sulfur Clusters by Carbene Ligation: the [FenSn]0 Oxidation Levels (n = 4, 8) Journal of the American Chemical Society. Jul, 2008 | Pubmed ID: 18593124 Multiple Erythematous Eroded Patches and Papules on the Scalp Archives of Dermatology. Jan, 2008 | Pubmed ID: 18209179 Identification of Novel Antipoxviral Agents: Mitoxantrone Inhibits Vaccinia Virus Replication by Blocking Virion Assembly Journal of Virology. Dec, 2007 | Pubmed ID: 17928345 Dermoscopic and Reflectance Confocal Microscope Findings of Trichoepithelioma Dermatology (Basel, Switzerland). 2007 | Pubmed ID: 17911996 Synthesis, Structure, Reactivity, and Thermal Isomerization of Boron-substituted 13-vertex Cobaltacarboranes (eta5-Cp)Co(eta6-R2C2B10Me8H2) (R = H, Et) Inorganic Chemistry. Apr, 2007 | Pubmed ID: 17343377 Role of C,c'-linkage in the Formation and Stabilization of Supercarboranes. Synthesis and Structure of Carbon-atoms-apart 13-vertex Carborane and 14-vertex Metallacarborane Journal of the American Chemical Society. Jan, 2007 | Pubmed ID: 17199267 Vaccinia Virus Infection Attenuates Innate Immune Responses and Antigen Presentation by Epidermal Dendritic Cells Journal of Virology. Oct, 2006 | Pubmed ID: 17005676 Nickel-mediated Regioselective [2 + 2 + 2] Cycloaddition of Carboryne with Alkynes Journal of the American Chemical Society. Jun, 2006 | Pubmed ID: 16771473 Synthesis and Structure of 14- and 15-vertex Ruthenacarboranes Angewandte Chemie (International Ed. in English). Jun, 2006 | Pubmed ID: 16729344 Synthesis, Structure, and Reactivity of 13-vertex Carboranes and 14-vertex Metallacarboranes Journal of the American Chemical Society. Apr, 2006 | Pubmed ID: 16608358 Synthesis, Structure, and Reactivity of a Zirconocene-carboryne Precursor Journal of the American Chemical Society. Oct, 2005 | Pubmed ID: 16201782 Synthesis, Reactivity, and Structural Characterization of a 14-vertex Carborane Angewandte Chemie (International Ed. in English). Mar, 2005 | Pubmed ID: 15726559 Metal Carbene-promoted Sequential Transformations for the Enantioselective Synthesis of Highly Functionalized Cycloheptadienes Journal of the American Chemical Society. Feb, 2005 | Pubmed ID: 15686344 Zirconocene-mediated Intermolecular Coupling of Si-tethered Diynes with Alkynes, Ketones, Aldehydes, and Isocyanates by Means of Novel Skeletal Rearrangement of Zirconacyclobutene-silacyclobutene and Zirconacyclohexadiene-silacyclobutene Fused-ring Intermediates Chemistry (Weinheim an Der Bergstrasse, Germany). Mar, 2005 | Pubmed ID: 15674981 [Study on Quality Evaluation Methods of Pretreatment for Polystyrene-type Macroporous Absorbing Resins] Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. Nov, 2004 | Pubmed ID: 15656131 Detection and Quantification of the Human IgG4 Half-molecule, HL, from Unpurified Cell-culture Supernatants Biotechnology and Applied Biochemistry. Dec, 2004 | Pubmed ID: 14979869 Thalidomide Inhibits Tumor Necrosis Factor-alpha Production and Antigen Presentation by Langerhans Cells The Journal of Investigative Dermatology. Nov, 2003 | Pubmed ID: 14708607 Altered Cutaneous Immune Parameters in Transgenic Mice Overexpressing Viral IL-10 in the Epidermis The Journal of Clinical Investigation. Jun, 2003 | Pubmed ID: 12813028 Improvement of Monoclonal Antibody Production in Hybridoma Cells by Dimethyl Sulfoxide Biotechnology Progress. Jan-Feb, 2003 | Pubmed ID: 12573019 A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics Shuangping Shi1, Russ G.G. Condon1, Liang Deng1, Jason Saunders1, Finn Hung1, Yung-Shyeng Tsao1, Zhong Liu1 1Merck Research Laboratory, Merck & Co., Inc JoVE 3010 Medicine
A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics Shuangping Shi1, Russ G.G. Condon1, Liang Deng1, Jason Saunders1, Finn Hung1, Yung-Shyeng Tsao1, Zhong Liu1 1Merck Research Laboratory, Merck & Co., Inc JoVE 3010 Medicine