Liangcai Gu Department of Biochemistry, School of Medicine University of Washington Biography Publications Institution JoVE Articles Liangcai GuAssistant Professor Dr. Gu received Ph.D. on natural product biosynthesis and mechanistic enzymology with Professor David Sherman at the University of Michigan, and then did his postdoctoral research with Professor George Church at Harvard to develop a novel molecular barcoding and in situ DNA sequencing technology, SMI-seq, for massively parallel protein interaction quantification. His own lab at the University of Washington Department of Biochemistry is developing protein and DNA barcoding and sequencing methods for protein engineering, for example, small-molecule ligand and light controlled genetically encoded biosensors, and high-resolution spatial transcriptomics and proteomics. The lab is interested in applying these technologies to address challenges in precision pharmacology for neurological and immunological disorders. Publications 결합 단일 도메인 항체 라이브러리의 단계별 파지 선택에 의해 고도로 특이적 화학적으로 유도된 단백질 이분화 시스템 생성 Luis Gomez-Castillo*1, Kurumi Watanabe*1, Huayi Jiang*1, Shoukai Kang1, Liangcai Gu1 1Department of Biochemistry and Institute for Protein Design, University of Washington JoVE 60738 Biochemistry
결합 단일 도메인 항체 라이브러리의 단계별 파지 선택에 의해 고도로 특이적 화학적으로 유도된 단백질 이분화 시스템 생성 Luis Gomez-Castillo*1, Kurumi Watanabe*1, Huayi Jiang*1, Shoukai Kang1, Liangcai Gu1 1Department of Biochemistry and Institute for Protein Design, University of Washington JoVE 60738 Biochemistry