Liangxu Xie Institute of Bioinformatics and Medical Engineering Jiangsu University of Technology Biography Publications Institution JoVE Articles Liangxu XieDr. Liangxu Xie is Associate Professor at Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, Jiangsu University of Technology. He earned B.Sc. degree from National Base of Chemistry, Shandong University in 2011. Then he received his Ph.D. degree in 2016 from the University of Hong Kong with the supervision of Prof. Hao Hu. From 2016 to 2017, he worked as Research Assistant in the group of Prof. Kwong-Yu Chan at the University of Hong Kong. From 2017 to 2018, he joined the group of Prof. Xuhui Huang as Research Associate with the research on free energy calculations and deep learning in drug discovery at Hong Kong University of Science and Technology. He was appointed as Zhong-Wu Specially Appointed Professor in 2019 at Jiangsu University of Technology.His research interest focuses on exploring the underlying mechanism of biological systems, including enzymatic reaction and protein conformational transformation processes. Computer simulations complement experiments and provide mechanistic insights for a range of complex processes. Recently, he is devoted to combining QM/MM molecular dynamics simulations, enhanced sampling methods, free energy calculation, and deep learning methods together to aid material and drug design. Publications Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method Zhihui Tu1,2, Jian Yin3, Liangxu Xie4 1State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 2University of Chinese Academy of Sciences, 3XtalPi Inc. (Shenzhen Jingtai Technology Co., Ltd.), 4Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, Jiangsu University of Technology JoVE 60040 Chemistry
Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method Zhihui Tu1,2, Jian Yin3, Liangxu Xie4 1State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 2University of Chinese Academy of Sciences, 3XtalPi Inc. (Shenzhen Jingtai Technology Co., Ltd.), 4Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, Jiangsu University of Technology JoVE 60040 Chemistry
