Lien Van Hoecke

Publications

• Choroid Plexus-derived Extracellular Vesicles Exhibit Brain Targeting Characteristics
  Biomaterials. Nov, 2022  |   Pubmed ID: 36302306
• A Mouse Model of Hepatic Encephalopathy: Bile Duct Ligation Induces Brain Ammonia Overload, Glial Cell Activation and Neuroinflammation
  Scientific Reports. Oct, 2022  |   Pubmed ID: 36266427
• Recent Insights into Viral Infections As a Trigger and Accelerator in Alzheimer's Disease
  Drug Discovery Today. Aug, 2022  |   Pubmed ID: 35987492
• The Tremendous Biomedical Potential of Bacterial Extracellular Vesicles
  Trends in Biotechnology. Oct, 2022  |   Pubmed ID: 35581020
• Fighting Fire with Fire: The Immune System Might Be Key in Our Fight Against Alzheimer's Disease
  Drug Discovery Today. May, 2022  |   Pubmed ID: 35032668
• The Impact of Systemic Inflammation on Alzheimer's Disease Pathology
  Frontiers in Immunology. 2021  |   Pubmed ID: 35069578
• Anti-Inflammatory Mesenchymal Stromal Cell-Derived Extracellular Vesicles Improve Pathology in Niemann-Pick Type C Disease
  Biomedicines. Dec, 2021  |   Pubmed ID: 34944681
• Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C
  Frontiers in Cellular Neuroscience. 2021  |   Pubmed ID: 34720883
• Low-grade Peripheral Inflammation Affects Brain Pathology in the Appmouse Model of Alzheimer's Disease
  Acta Neuropathologica Communications. Oct, 2021  |   Pubmed ID: 34620254
• The Neurogliovascular Unit in Hepatic Encephalopathy
  JHEP Reports : Innovation in Hepatology. Oct, 2021  |   Pubmed ID: 34611619
• Therapy with M2e-Specific IgG Selects for an Influenza A Virus Mutant with Delayed Matrix Protein 2 Expression
  MBio. Aug, 2021  |   Pubmed ID: 34253060
• MRNA in Cancer Immunotherapy: Beyond a Source of Antigen
  Molecular Cancer. Mar, 2021  |   Pubmed ID: 33658037
• Intracellular Delivery of MRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation
  Nano-micro Letters. Sep, 2020  |   Pubmed ID: 34138203
• The Opposing Effect of Type I IFN on the T Cell Response by Non-modified MRNA-Lipoplex Vaccines Is Determined by the Route of Administration
  Molecular Therapy. Nucleic Acids. Dec, 2020  |   Pubmed ID: 33230442
• Recombinant Viruses Delivering the Necroptosis Mediator MLKL Induce a Potent Antitumor Immunity in Mice
  Oncoimmunology. Aug, 2020  |   Pubmed ID: 32923163
• Specific Targeting of IL-1β Activity to CD8 T Cells Allows for Safe Use As a Vaccine Adjuvant
  NPJ Vaccines. 2020  |   Pubmed ID: 32714571
• MRNA Encoding a Bispecific Single Domain Antibody Construct Protects Against Influenza A Virus Infection in Mice
  Molecular Therapy. Nucleic Acids. Jun, 2020  |   Pubmed ID: 32438313
• Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection
  Frontiers in Immunology. 2019  |   Pubmed ID: 31921179
• Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells
  International Journal of Molecular Sciences. Aug, 2019  |   Pubmed ID: 31480289
• Intranodal Administration of MRNA Encoding Nucleoprotein Provides Cross-strain Immunity Against Influenza in Mice
  Journal of Translational Medicine. Jul, 2019  |   Pubmed ID: 31345237
• Mx1 in Hematopoietic Cells Protects Against Thogoto Virus Infection
  Journal of Virology. Aug, 2019  |   Pubmed ID: 31092574
• How MRNA Therapeutics Are Entering the Monoclonal Antibody Field
  Journal of Translational Medicine. Feb, 2019  |   Pubmed ID: 30795778
• Therapeutic Anti-tumor Immunity Directed Against Neo-epitopes by Intratumor Delivery of MRNA Encoding MLKL
  Cell Stress. Oct, 2018  |   Pubmed ID: 31225452
• Treatment with MRNA Coding for the Necroptosis Mediator MLKL Induces Antitumor Immunity Directed Against Neo-epitopes
  Nature Communications. 08, 2018  |   Pubmed ID: 30143632
• Surfactant Protein B (SP-B) Enhances the Cellular SiRNA Delivery of Proteolipid Coated Nanogels for Inhalation Therapy
  Acta Biomaterialia. Sep, 2018  |   Pubmed ID: 30118853
• Potent Anti-viral Vaccine Adjuvant Based on PH-degradable Nanogels with Covalently Linked Small Molecule Imidazoquinoline TLR7/8 Agonist
  Biomaterials. Sep, 2018  |   Pubmed ID: 29573820
• Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B As a Vaccine Adjuvant
  Bioconjugate Chemistry. Mar, 2018  |   Pubmed ID: 29172458
• Arginine-Rich Peptide-Based MRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide
  Advanced Healthcare Materials. Jul, 2017  |   Pubmed ID: 28436620
• Chemical-controlled Activation of Antiviral Myxovirus Resistance Protein 1
  The Journal of Biological Chemistry. Feb, 2017  |   Pubmed ID: 28011636
• Cholesterol-sensing Liver X Receptors Stimulate Th2-driven Allergic Eosinophilic Asthma in Mice
  Immunity, Inflammation and Disease. Sep, 2016  |   Pubmed ID: 27621817
• Type I Interferons Interfere with the Capacity of MRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2016  |   Pubmed ID: 27506450
• Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2016  |   Pubmed ID: 27434590
• Mycobacterium Tuberculosis-associated Synthetic Mycolates Differentially Exert Immune Stimulatory Adjuvant Activity
  European Journal of Immunology. Sep, 2016  |   Pubmed ID: 27349218
• GM-CSF Treatment Prevents Respiratory Syncytial Virus-induced Pulmonary Exacerbation Responses in Postallergic Mice by Stimulating Alveolar Macrophage Maturation
  The Journal of Allergy and Clinical Immunology. Mar, 2016  |   Pubmed ID: 26560044