Lies Langouche Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine KU Leuven Biography Publications Institution JoVE Articles Lies Langouche has not added a biography. If you are Lies Langouche and would like to personalize this page please email our Author Liaison for assistance. Publications Proliferation and Differentiation of Adipose Tissue in Prolonged Lean and Obese Critically Ill Patients Intensive Care Medicine Experimental. Dec, 2017 | Pubmed ID: 28303483 Premorbid Obesity, but Not Nutrition, Prevents Critical Illness-induced Muscle Wasting and Weakness Journal of Cachexia, Sarcopenia and Muscle. Feb, 2017 | Pubmed ID: 27897405 Drug-induced HPA Axis Alterations During Acute Critical Illness: a Multivariable Association Study Clinical Endocrinology. Jan, 2017 | Pubmed ID: 27422812 Circulating 3-T1AM and 3,5-T2 in Critically Ill Patients: A Cross-Sectional Observational Study Thyroid : Official Journal of the American Thyroid Association. Dec, 2016 | Pubmed ID: 27676423 Cholestatic Liver (dys)function During Sepsis and Other Critical Illnesses Intensive Care Medicine. Jan, 2016 | Pubmed ID: 26392257 Thyroid Function in Critically Ill Patients The Lancet. Diabetes & Endocrinology. Oct, 2015 | Pubmed ID: 26071885 Neuropathological Correlates of Hyperglycemia During Prolonged Polymicrobial Sepsis in Mice Shock (Augusta, Ga.). Sep, 2015 | Pubmed ID: 26009823 Liver X Receptor Activation Enhances CVB3 Viral Replication During Myocarditis by Stimulating Lipogenesis Cardiovascular Research. Jul, 2015 | Pubmed ID: 25998987 Effect of Early Parenteral Nutrition on the HPA Axis and on Treatment With Corticosteroids in Intensive Care Patients The Journal of Clinical Endocrinology and Metabolism. Jul, 2015 | Pubmed ID: 25942482 Hypothalamic-pituitary Hormones During Critical Illness: a Dynamic Neuroendocrine Response Handbook of Clinical Neurology. 2014 | Pubmed ID: 25248583 Impact of Duration of Critical Illness on the Adrenal Glands of Human Intensive Care Patients The Journal of Clinical Endocrinology and Metabolism. Nov, 2014 | Pubmed ID: 25062464 The Authors Reply Critical Care Medicine. May, 2014 | Pubmed ID: 24736366 Withholding Parenteral Nutrition During Critical Illness Increases Plasma Bilirubin but Lowers the Incidence of Biliary Sludge Hepatology (Baltimore, Md.). Jul, 2014 | Pubmed ID: 24213952 Impact of Parenteral Nutrition Versus Fasting on Hepatic Bile Acid Production and Transport in a Rabbit Model of Prolonged Critical Illness Shock (Augusta, Ga.). Jan, 2014 | Pubmed ID: 24089008 Critical Illness Induces Nutrient-independent Adipogenesis and Accumulation of Alternatively Activated Tissue Macrophages Critical Care (London, England). Sep, 2013 | Pubmed ID: 24020372 Impact of Early Parenteral Nutrition on Muscle and Adipose Tissue Compartments During Critical Illness Critical Care Medicine. Oct, 2013 | Pubmed ID: 23860247 Reduced Cortisol Metabolism During Critical Illness The New England Journal of Medicine. Apr, 2013 | Pubmed ID: 23506003 Impact of Early Nutrient Restriction During Critical Illness on the Nonthyroidal Illness Syndrome and Its Relation with Outcome: a Randomized, Controlled Clinical Study The Journal of Clinical Endocrinology and Metabolism. Mar, 2013 | Pubmed ID: 23348400 Endocrine, Metabolic, and Morphologic Alterations of Adipose Tissue During Critical Illness Critical Care Medicine. Jan, 2013 | Pubmed ID: 23135416 Effect of Tight Glucose Control with Insulin on the Thyroid Axis of Critically Ill Children and Its Relation with Outcome The Journal of Clinical Endocrinology and Metabolism. Oct, 2012 | Pubmed ID: 22872689 Contribution of Nutritional Deficit to the Pathogenesis of the Nonthyroidal Illness Syndrome in Critical Illness: a Rabbit Model Study Endocrinology. Feb, 2012 | Pubmed ID: 22166982 Critical Illness Induces Alternative Activation of M2 Macrophages in Adipose Tissue Critical Care (London, England). 2011 | Pubmed ID: 22018099 Critical Illness Evokes Elevated Circulating Bile Acids Related to Altered Hepatic Transporter and Nuclear Receptor Expression Hepatology (Baltimore, Md.). Nov, 2011 | Pubmed ID: 21800341 Molecular Analysis of Sepsis-induced Changes in the Liver: Microarray Study in a Porcine Model of Acute Fecal Peritonitis with Fluid Resuscitation Shock (Augusta, Ga.). Oct, 2010 | Pubmed ID: 20610940 Tight Glycemic Control Protects the Myocardium and Reduces Inflammation in Neonatal Heart Surgery The Annals of Thoracic Surgery. Jul, 2010 | Pubmed ID: 20609741 Alterations in Adipose Tissue During Critical Illness: An Adaptive and Protective Response? American Journal of Respiratory and Critical Care Medicine. Aug, 2010 | Pubmed ID: 20442437 Molecular Mechanisms Behind Clinical Benefits of Intensive Insulin Therapy During Critical Illness: Glucose Versus Insulin Best Practice & Research. Clinical Anaesthesiology. Dec, 2009 | Pubmed ID: 20108584 Changes in the Central Component of the Hypothalamus-pituitary-thyroid Axis in a Rabbit Model of Prolonged Critical Illness Critical Care (London, England). 2009 | Pubmed ID: 19747372 Adiponectin, Retinol-binding Protein 4, and Leptin in Protracted Critical Illness of Pulmonary Origin Critical Care (London, England). 2009 | Pubmed ID: 19589139 Expression of Thyroid Hormone Transporters During Critical Illness European Journal of Endocrinology. Aug, 2009 | Pubmed ID: 19439506 Polymorphisms in Innate Immunity Genes Predispose to Bacteremia and Death in the Medical Intensive Care Unit Critical Care Medicine. Jan, 2009 | Pubmed ID: 19050632 Effect of Insulin Therapy on Coagulation and Fibrinolysis in Medical Intensive Care Patients Critical Care Medicine. May, 2008 | Pubmed ID: 18434900 Modulation of Regional Nitric Oxide Metabolism: Blood Glucose Control or Insulin? Intensive Care Medicine. Aug, 2008 | Pubmed ID: 18427775 Glycemic Control Modulates Arginine and Asymmetrical-dimethylarginine Levels During Critical Illness by Preserving Dimethylarginine-dimethylaminohydrolase Activity Endocrinology. Jun, 2008 | Pubmed ID: 18292189 Tight Blood Glucose Control: What is the Evidence? Critical Care Medicine. Sep, 2007 | Pubmed ID: 17713399 Effect of Intensive Insulin Therapy on Insulin Sensitivity in the Critically Ill The Journal of Clinical Endocrinology and Metabolism. Oct, 2007 | Pubmed ID: 17666481 Tight Blood Glucose Control with Insulin in the ICU: Facts and Controversies Chest. Jul, 2007 | Pubmed ID: 17625087 Indication and Practical Use of Intensive Insulin Therapy in the Critically Ill Current Opinion in Critical Care. Aug, 2007 | Pubmed ID: 17599008 The Type II Iodothyronine Deiodinase is Up-regulated in Skeletal Muscle During Prolonged Critical Illness The Journal of Clinical Endocrinology and Metabolism. Aug, 2007 | Pubmed ID: 17504898 Modulating the Endocrine Response in Sepsis: Insulin and Blood Glucose Control Novartis Foundation Symposium. 2007 | Pubmed ID: 17380796 Therapy Insight: the Effect of Tight Glycemic Control in Acute Illness Nature Clinical Practice. Endocrinology & Metabolism. Mar, 2007 | Pubmed ID: 17315035 The Dynamic Neuroendocrine Response to Critical Illness Endocrinology and Metabolism Clinics of North America. Dec, 2006 | Pubmed ID: 17127146 Endocrine Aspects of Acute and Prolonged Critical Illness Nature Clinical Practice. Endocrinology & Metabolism. Jan, 2006 | Pubmed ID: 16932250 Intensive Insulin Therapy in the Intensive Care Unit: Update on Clinical Impact and Mechanisms of Action Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. Jul-Aug, 2006 | Pubmed ID: 16905512 Survival Benefits of Intensive Insulin Therapy in Critical Illness: Impact of Maintaining Normoglycemia Versus Glycemia-independent Actions of Insulin Diabetes. Apr, 2006 | Pubmed ID: 16567534 Glucose Metabolism and Insulin Therapy Critical Care Clinics. Jan, 2006 | Pubmed ID: 16399023 The Role of Insulin Therapy in Critically Ill Patients Treatments in Endocrinology. 2005 | Pubmed ID: 16318401 Intensive Insulin Therapy Protects the Endothelium of Critically Ill Patients The Journal of Clinical Investigation. Aug, 2005 | Pubmed ID: 16075063 Glycemic and Nonglycemic Effects of Insulin: How Do They Contribute to a Better Outcome of Critical Illness? Current Opinion in Critical Care. Aug, 2005 | Pubmed ID: 16015107 Structure-activity Relationship and Signal Transduction of Gamma-MSH Peptides in GH3 Cells: Further Evidence for a New Melanocortin Receptor Peptides. Jun, 2002 | Pubmed ID: 12126734 Stimulation of Intracellular Free Calcium in GH3 Cells Byγ 3-Melanocyte-Stimulating Hormone. Involvement of a Novel Melanocortin Receptor? Endocrinology. Jan, 2001 | Pubmed ID: 28201334 Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness Sarah Derde1, Steven Thiessen1, Chloë Goossens1, Thomas Dufour1, Greet Van den Berghe1, Lies Langouche1 1Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven JoVE 55553 Medicine
Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness Sarah Derde1, Steven Thiessen1, Chloë Goossens1, Thomas Dufour1, Greet Van den Berghe1, Lies Langouche1 1Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven JoVE 55553 Medicine
