Liping Yu Department of Medicine, Division of Nephrology The Icahn School of Medicine at Mount Sinai Biography Publications Institution JoVE Articles Liping Yu has not added a biography. If you are Liping Yu and would like to personalize this page please email our Author Liaison for assistance. Publications High-Throughput Multiplex Electrochemiluminescence Assay Applicable to General Population Screening for Type 1 Diabetes and Celiac Disease Diabetes Technology & Therapeutics. Jul, 2022 | Pubmed ID: 35238620 Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study Diabetes Care. 03, 2022 | Pubmed ID: 35043162 High-affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve Risk Prediction for Type 1 Diabetes The Journal of Clinical Endocrinology and Metabolism. 11, 2021 | Pubmed ID: 34343303 Improving Clinical Utility of GAD65 Autoantibodies by Electrochemiluminescence Assay and Clinical Phenotype when Identifying Autoimmune Adult-onset Diabetes Diabetologia. 09, 2021 | Pubmed ID: 34272582 Novel Autoantibodies to the β-cell Surface Epitopes of ZnT8 in Patients Progressing to Type-1 Diabetes Journal of Autoimmunity. 08, 2021 | Pubmed ID: 34130115 Autoimmune Thyroid Disease Correlates to Islet Autoimmunity on Zinc Transporter 8 Autoantibody Endocrine Connections. May, 2021 | Pubmed ID: 33909592 Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors Frontiers in Endocrinology. Month, 2021 | Pubmed ID: 33841327 Large-Scale Screening in General Population Children for Celiac Disease with a Multiplex Electrochemiluminescence (ECL) Assay Journal of Immunology Research. Month, 2020 | Pubmed ID: 33426098 Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms Diabetes. 11, 2020 | Pubmed ID: 32843568 The Diabetic Microenvironment Causes Mitochondrial Oxidative Stress in Glomerular Endothelial Cells and Pathological Crosstalk with Podocytes Cell Communication and Signaling : CCS. 07, 2020 | Pubmed ID: 32641054 Cost and Cost-Effectiveness of Large-Scale Screening for Type 1 Diabetes in Colorado Diabetes Care. Apr, 2020 | Pubmed ID: 32327420 Islet Autoantibodies in Disease Prediction and Pathogenesis Diabetology International. Jan, 2020 | Pubmed ID: 31949998 High-throughput Multiplexed Autoantibody Detection to Screen Type 1 Diabetes and Multiple Autoimmune Diseases Simultaneously EBioMedicine. Sep, 2019 | Pubmed ID: 31447394 Screening Children for Type 1 Diabetes-associated Antibodies at Community Health Fairs Pediatric Diabetes. 11, 2019 | Pubmed ID: 31376227 Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes Diabetes Care. 02, 2019 | Pubmed ID: 30061316 PD-1 Inhibitor Immune-Related Adverse Events in Patients With Preexisting Endocrine Autoimmunity The Journal of Clinical Endocrinology and Metabolism. 10, 2018 | Pubmed ID: 30124874 Characteristics of Slow Progression to Diabetes in Multiple Islet Autoantibody-positive Individuals from Five Longitudinal Cohorts: the SNAIL Study Diabetologia. 06, 2018 | Pubmed ID: 29532109 A Subclass of Serum Anti-ZnT8 Antibodies Directed to the Surface of Live Pancreatic β-cells The Journal of Biological Chemistry. Jan, 2018 | Pubmed ID: 29184000 Dominant-negative Loss of Function Arises from a Second, More Frequent Variant Within the SAND Domain of Autoimmune Regulator (AIRE) Journal of Autoimmunity. Mar, 2018 | Pubmed ID: 29129473 Islet Autoantibody Detection by Electrochemiluminescence (ECL) Assay Journal of Clinical & Cellular Immunology. Month, 2017 | Pubmed ID: 29487479 Altered Homeostasis and Development of Regulatory T Cell Subsets Represent an IL-2R-dependent Risk for Diabetes in NOD Mice Science Signaling. Dec, 2017 | Pubmed ID: 29259102 T1D Autoantibodies: Room for Improvement? Current Opinion in Endocrinology, Diabetes, and Obesity. Aug, 2017 | Pubmed ID: 28509692 The Use of Electrochemiluminescence Assays to Predict Autoantibody and Glycemic Progression Toward Type 1 Diabetes in Individuals with Single Autoantibodies Diabetes Technology & Therapeutics. Feb, 2017 | Pubmed ID: 28177779 Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development Diabetes Care. Apr, 2017 | Pubmed ID: 28174261 Higher Sensitivity and Earlier Identification of Celiac Disease Autoimmunity by a Nonradioactive Assay for Transglutaminase Autoantibodies Journal of Immunology Research. Month, 2016 | Pubmed ID: 28127566 Islet-derived CD4 T-cells Targeting Proinsulin in Human Autoimmune Diabetes Diabetes. Dec, 2016 | Pubmed ID: 27920090 High-Throughput Screening in General Population for Type 1 Diabetes Diabetes Technology & Therapeutics. 11, 2016 | Pubmed ID: 27860497 Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects? Diabetes Care. 10, 2016 | Pubmed ID: 27456836 Celiac Disease Autoimmunity in Patients with Autoimmune Diabetes and Thyroid Disease Among Chinese Population PloS One. Month, 2016 | Pubmed ID: 27427767 Predictors of Slow Progression to Diabetes in Children with Multiple Islet Autoantibodies Journal of Autoimmunity. Aug, 2016 | Pubmed ID: 27255734 The Heterogeneity of Islet Autoantibodies and the Progression of Islet Failure in Type 1 Diabetic Patients Science China. Life Sciences. Sep, 2016 | Pubmed ID: 27225179 CRISPR-Cas9-Mediated Modification of the NOD Mouse Genome With Ptpn22R619W Mutation Increases Autoimmune Diabetes Diabetes. 08, 2016 | Pubmed ID: 27207523 Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes PloS One. Month, 2016 | Pubmed ID: 27031512 ECL-IAA and ECL-GADA Can Identify High-Risk Single Autoantibody-Positive Relatives in the TrialNet Pathway to Prevention Study Diabetes Technology & Therapeutics. 07, 2016 | Pubmed ID: 26991969 Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes Diabetes. May, 2016 | Pubmed ID: 26983959 A Multiplex Assay Combining Insulin, GAD, IA-2 and Transglutaminase Autoantibodies to Facilitate Screening for Pre-type 1 Diabetes and Celiac Disease Journal of Immunological Methods. Mar, 2016 | Pubmed ID: 26809048 Islet Autoantibody Detection by Electrochemiluminescence (ECL) Assay Methods in Molecular Biology (Clifton, N.J.). Month, 2016 | Pubmed ID: 26659802 Feasibility of Screening for T1D and Celiac Disease in a Pediatric Clinic Setting Pediatric Diabetes. Sep, 2016 | Pubmed ID: 26251221 Use of Dried Capillary Blood Sampling for Islet Autoantibody Screening in Relatives: A Feasibility Study Diabetes Technology & Therapeutics. Dec, 2015 | Pubmed ID: 26375197 Regulatory Vs. Inflammatory Cytokine T-cell Responses to Mutated Insulin Peptides in Healthy and Type 1 Diabetic Subjects Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015 | Pubmed ID: 25831495 Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes Diabetes. Aug, 2015 | Pubmed ID: 25829454 Electrochemiluminescence Assays for Insulin and Glutamic Acid Decarboxylase Autoantibodies Improve Prediction of Type 1 Diabetes Risk Diabetes Technology & Therapeutics. Feb, 2015 | Pubmed ID: 25562486 Exploring T Cell Reactivity to Gliadin in Young Children with Newly Diagnosed Celiac Disease Autoimmune Diseases. Month, 2014 | Pubmed ID: 24724018 Inhibition of Increased Circulating Tfh Cell by Anti-CD20 Monoclonal Antibody in Patients with Type 1 Diabetes PloS One. Month, 2013 | Pubmed ID: 24278195 GAD65 Autoantibodies Detected by Electrochemiluminescence Assay Identify High Risk for Type 1 Diabetes Diabetes. Dec, 2013 | Pubmed ID: 23974918 Proinsulin/Insulin Autoantibodies Measured with Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity Diabetes Care. Aug, 2013 | Pubmed ID: 23423694 Distinguishing Persistent Insulin Autoantibodies with Differential Risk: Nonradioactive Bivalent Proinsulin/insulin Autoantibody Assay Diabetes. Jan, 2012 | Pubmed ID: 22124462 Predicting the Onset of Addison's Disease: ACTH, Renin, Cortisol and 21-hydroxylase Autoantibodies Clinical Endocrinology. May, 2012 | Pubmed ID: 22066755 Rituximab Selectively Suppresses Specific Islet Antibodies Diabetes. Oct, 2011 | Pubmed ID: 21831969 Age of Islet Autoantibody Appearance and Mean Levels of Insulin, but Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young Diabetes Care. Jun, 2011 | Pubmed ID: 21562325 Human Type 1 Diabetes is Associated with T Cell Autoimmunity to Zinc Transporter 8 Journal of Immunology (Baltimore, Md. : 1950). May, 2011 | Pubmed ID: 21471440 Additional Autoimmune Disease Found in 33% of Patients at Type 1 Diabetes Onset Diabetes Care. May, 2011 | Pubmed ID: 21430083 Triple Chimeric Islet Autoantigen IA2-ZnT8WR to Facilitate Islet Autoantibody Determination Journal of Immunological Methods. Feb, 2010 | Pubmed ID: 20035758 Homozygosity of the Polymorphism MICA5.1 Identifies Extreme Risk of Progression to Overt Adrenal Insufficiency Among 21-hydroxylase Antibody-positive Patients with Type 1 Diabetes The Journal of Clinical Endocrinology and Metabolism. Nov, 2009 | Pubmed ID: 19820007 A Report on the International Transglutaminase Autoantibody Workshop for Celiac Disease The American Journal of Gastroenterology. Jan, 2009 | Pubmed ID: 19098864 Type 1 Diabetes: Chronic Progressive Autoimmune Disease Novartis Foundation Symposium. Month, 2008 | Pubmed ID: 19203094 SlC30A8 is a Major Target of Humoral Autoimmunity in Type 1 Diabetes and a Predictive Marker in Prediabetes Annals of the New York Academy of Sciences. Dec, 2008 | Pubmed ID: 19120307 A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes Diabetes. Oct, 2008 | Pubmed ID: 18591387 Isolation of Conditionally Immortalized Mouse Glomerular Endothelial Cells with Fluorescent Mitochondria Rihab Bouchareb1, Liping Yu1, Emelie Lassen1, Ilse S. Daehn1 1Department of Medicine, Division of Nephrology, The Icahn School of Medicine at Mount Sinai JoVE 64147 Biology A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19 Xiaofan Jia*1, Ling He*1,2, Dongmei Miao1, Caiguo Zhang1, Marian Rewers1, Liping Yu1 1Barbara Davis Center for Diabetes, University of Colorado School of Medicine, 2Department of Endocrinology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology JoVE 63787 Immunology and Infection A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases Xiaofan Jia*1,2, Ling He*1,3, Yong Gu1, Hilary High1, Liping Yu1 1Barbara Davis Center for Diabetes, University of Colorado School of Medicine, 2Department of Endocrinology, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, 3Department of endocrinology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology JoVE 61160 Medicine Electrochemiluminescence Assays for Human Islet Autoantibodies Yong Gu1,2, Zhiyuan Zhao1, Dongmei Miao1, Hilary High1, Tao Yang2, Liping Yu1 1Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, 2Department of Endocrinology, First Affiliated Hospital of Nanjing Medical University JoVE 57227 Immunology and Infection
Isolation of Conditionally Immortalized Mouse Glomerular Endothelial Cells with Fluorescent Mitochondria Rihab Bouchareb1, Liping Yu1, Emelie Lassen1, Ilse S. Daehn1 1Department of Medicine, Division of Nephrology, The Icahn School of Medicine at Mount Sinai JoVE 64147 Biology
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19 Xiaofan Jia*1, Ling He*1,2, Dongmei Miao1, Caiguo Zhang1, Marian Rewers1, Liping Yu1 1Barbara Davis Center for Diabetes, University of Colorado School of Medicine, 2Department of Endocrinology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology JoVE 63787 Immunology and Infection
A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases Xiaofan Jia*1,2, Ling He*1,3, Yong Gu1, Hilary High1, Liping Yu1 1Barbara Davis Center for Diabetes, University of Colorado School of Medicine, 2Department of Endocrinology, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, 3Department of endocrinology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology JoVE 61160 Medicine
Electrochemiluminescence Assays for Human Islet Autoantibodies Yong Gu1,2, Zhiyuan Zhao1, Dongmei Miao1, Hilary High1, Tao Yang2, Liping Yu1 1Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, 2Department of Endocrinology, First Affiliated Hospital of Nanjing Medical University JoVE 57227 Immunology and Infection
