Lorenz Studer The Center for Stem Cell Biology, Developmental Biology Program Memorial Sloan-Kettering Cancer Center Biography Publications Institution JoVE Articles Lorenz Studer has not added a biography. If you are Lorenz Studer and would like to personalize this page please email our Author Liaison for assistance. Publications Deriving Human ENS Lineages for Cell Therapy and Drug Discovery in Hirschsprung Disease Nature. Feb, 2016 | Pubmed ID: 26863197 α-Synuclein-induced Lysosomal Dysfunction Occurs Through Disruptions in Protein Trafficking in Human Midbrain Synucleinopathy Models Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26839413 Correction: Targeting Homologous Recombination in Notch-Driven C. Elegans Stem Cell and Human Tumors PloS One. 2016 | Pubmed ID: 26799319 Functional Connectivity Under Optogenetic Control Allows Modeling of Human Neuromuscular Disease Cell Stem Cell. Jan, 2016 | Pubmed ID: 26549107 Pluripotent Stem Cell-based Disease Modeling: Current Hurdles and Future Promise Current Opinion in Cell Biology. Dec, 2015 | Pubmed ID: 26629748 Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders Stem Cell Reports. Dec, 2015 | Pubmed ID: 26610635 Back and Forth in Time: Directing Age in IPSC-derived Lineages Brain Research. Nov, 2015 | Pubmed ID: 26592774 When Rejuvenation is a Problem: Challenges of Modeling Late-onset Neurodegenerative Disease Development (Cambridge, England). Sep, 2015 | Pubmed ID: 26395137 Neural Crest Cells from Dual SMAD Inhibition Current Protocols in Stem Cell Biology. 2015 | Pubmed ID: 26344232 Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2015 | Pubmed ID: 26290227 Targeting Homologous Recombination in Notch-Driven C. Elegans Stem Cell and Human Tumors PloS One. 2015 | Pubmed ID: 26120834 Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency Cell Stem Cell. Jun, 2015 | Pubmed ID: 26046759 Deciphering Human Cell-Autonomous Anti-HSV-1 Immunity in the Central Nervous System Frontiers in Immunology. 2015 | Pubmed ID: 26005444 Moving Stem Cells to the Clinic: Potential and Limitations for Brain Repair Neuron. Apr, 2015 | Pubmed ID: 25856494 The Polycomb Group Protein L3MBTL1 Represses a SMAD5-mediated Hematopoietic Transcriptional Program in Human Pluripotent Stem Cells Stem Cell Reports. Apr, 2015 | Pubmed ID: 25754204 Generation of Neuropeptidergic Hypothalamic Neurons from Human Pluripotent Stem Cells Development (Cambridge, England). Feb, 2015 | Pubmed ID: 25670790 Optogenetics Enables Functional Analysis of Human Embryonic Stem Cell-derived Grafts in a Parkinson's Disease Model Nature Biotechnology. Feb, 2015 | Pubmed ID: 25580598 A Cell Engineering Strategy to Enhance the Safety of Stem Cell Therapies Cell Reports. Sep, 2014 | Pubmed ID: 25242333 Aging in IPS Cells Aging. Apr, 2014 | Pubmed ID: 24799443 MHC-I Expression Renders Catecholaminergic Neurons Susceptible to T-cell-mediated Degeneration Nature Communications. 2014 | Pubmed ID: 24736453 Pluripotent Stem Cells in Regenerative Medicine: Challenges and Recent Progress Nature Reviews. Genetics. Feb, 2014 | Pubmed ID: 24434846 Enhancement of Polysialic Acid Expression Improves Function of Embryonic Stem-derived Dopamine Neuron Grafts in Parkinsonian Mice Stem Cells Translational Medicine. Jan, 2014 | Pubmed ID: 24311700 Human IPSC-based Modeling of Late-onset Disease Via Progerin-induced Aging Cell Stem Cell. Dec, 2013 | Pubmed ID: 24315443 Dual-SMAD Inhibition/WNT Activation-Based Methods to Induce Neural Crest and Derivatives from Human Pluripotent Stem Cells Methods in Molecular Biology (Clifton, N.J.). Dec, 2013 | Pubmed ID: 24301074 Specification of Functional Cranial Placode Derivatives from Human Pluripotent Stem Cells Cell Reports. Dec, 2013 | Pubmed ID: 24290755 Build-a-brain Cell Stem Cell. Oct, 2013 | Pubmed ID: 24094317 Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells Cell Stem Cell. May, 2013 | Pubmed ID: 23642365 Modeling Neural Crest Induction, Melanocyte Specification, and Disease-related Pigmentation Defects in HESCs and Patient-specific IPSCs Cell Reports. Apr, 2013 | Pubmed ID: 23583175 Human IPSC-derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination Cell Stem Cell. Feb, 2013 | Pubmed ID: 23395447 Adapting Human Pluripotent Stem Cells to High-throughput and High-content Screening Nature Protocols. Jan, 2013 | Pubmed ID: 23257981 Derivation of Dopaminergic Neurons from Pluripotent Stem Cells Progress in Brain Research. 2012 | Pubmed ID: 23195422 Large-scale Screening Using Familial Dysautonomia Induced Pluripotent Stem Cells Identifies Compounds That Rescue IKBKAP Expression Nature Biotechnology. Dec, 2012 | Pubmed ID: 23159879 Impaired Intrinsic Immunity to HSV-1 in Human IPSC-derived TLR3-deficient CNS Cells Nature. Oct, 2012 | Pubmed ID: 23103873 ZFX Controls the Self-renewal of Human Embryonic Stem Cells PloS One. 2012 | Pubmed ID: 22879936 Maturation of Spinal Motor Neurons Derived from Human Embryonic Stem Cells PloS One. 2012 | Pubmed ID: 22802953 Identification of Embryonic Stem Cell-derived Midbrain Dopaminergic Neurons for Engraftment The Journal of Clinical Investigation. Aug, 2012 | Pubmed ID: 22751106 Combined Small-molecule Inhibition Accelerates Developmental Timing and Converts Human Pluripotent Stem Cells into Nociceptors Nature Biotechnology. Jul, 2012 | Pubmed ID: 22750882 Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells Environmental Health Perspectives. Aug, 2012 | Pubmed ID: 22571897 The Expanding Role of MiR-302-367 in Pluripotency and Reprogramming Cell Cycle (Georgetown, Tex.). Apr, 2012 | Pubmed ID: 22436490 A Poised Chromatin Platform for TGF-β Access to Master Regulators Cell. Dec, 2011 | Pubmed ID: 22196728 Cellular Reprogramming: Recent Advances in Modeling Neurological Diseases The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22072658 Dopamine Neurons Derived from Human ES Cells Efficiently Engraft in Animal Models of Parkinson's Disease Nature. Dec, 2011 | Pubmed ID: 22056989 Genome-wide Identification of MicroRNA Targets in Human ES Cells Reveals a Role for MiR-302 in Modulating BMP Response Genes & Development. Oct, 2011 | Pubmed ID: 22012620 Converting Human Pluripotent Stem Cells to Neural Tissue and Neurons to Model Neurodegeneration Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21913095 Modelling Familial Dysautonomia in Human Induced Pluripotent Stem Cells Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Aug, 2011 | Pubmed ID: 21727134 Cell Fate Plug and Play: Direct Reprogramming and Induced Pluripotency Cell. Jun, 2011 | Pubmed ID: 21663788 MiR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells Cell Stem Cell. Jun, 2011 | Pubmed ID: 21624813 IPSCs Put to the Test Nature Biotechnology. Mar, 2011 | Pubmed ID: 21390027 Tumour-initiating Stem-like Cells in Human Prostate Cancer Exhibit Increased NF-κB Signalling Nature Communications. Jan, 2011 | Pubmed ID: 21245843 Genomic Safe Harbors Permit High β-globin Transgene Expression in Thalassemia Induced Pluripotent Stem Cells Nature Biotechnology. Jan, 2011 | Pubmed ID: 21151124 Neuroscience: Excessive Mobility Interrupted Nature. Nov, 2010 | Pubmed ID: 21085168 Single-molecule Analysis Reveals Changes in the DNA Replication Program for the POU5F1 Locus Upon Human Embryonic Stem Cell Differentiation Molecular and Cellular Biology. Sep, 2010 | Pubmed ID: 20647538 Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells Cell Stem Cell. Apr, 2010 | Pubmed ID: 20362538 Derivation of Neural Crest Cells from Human Pluripotent Stem Cells Nature Protocols. Apr, 2010 | Pubmed ID: 20360764 Prospective Isolation of Cortical Interneuron Precursors from Mouse Embryonic Stem Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2010 | Pubmed ID: 20357117 Expansion and Maintenance of Human Embryonic Stem Cell-derived Endothelial Cells by TGFbeta Inhibition is Id1 Dependent Nature Biotechnology. Feb, 2010 | Pubmed ID: 20081865 Induced Pluripotent Stem Cell Technology for the Study of Human Disease Nature Methods. Jan, 2010 | Pubmed ID: 20038952 Wnt1 Overexpression Leads to Enforced Cardiomyogenesis and Inhibition of Hematopoiesis in Murine Embryonic Stem Cells Stem Cells and Development. May, 2010 | Pubmed ID: 19422288 Enriched Motor Neuron Populations Derived from Bacterial Artificial Chromosome-transgenic Human Embryonic Stem Cells Clinical Neurosurgery. 2009 | Pubmed ID: 20214043 Protocols for Generating ES Cell-derived Dopamine Neurons Advances in Experimental Medicine and Biology. 2009 | Pubmed ID: 19731555 Modelling Pathogenesis and Treatment of Familial Dysautonomia Using Patient-specific IPSCs Nature. Sep, 2009 | Pubmed ID: 19693009 Stoichiometric and Temporal Requirements of Oct4, Sox2, Klf4, and C-Myc Expression for Efficient Human IPSC Induction and Differentiation Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19549847 Bmi-1 Cooperates with Foxg1 to Maintain Neural Stem Cell Self-renewal in the Forebrain Genes & Development. Mar, 2009 | Pubmed ID: 19270157 Highly Efficient Neural Conversion of Human ES and IPS Cells by Dual Inhibition of SMAD Signaling Nature Biotechnology. Mar, 2009 | Pubmed ID: 19252484 Too Much Sonic, Too Few Neurons Nature Neuroscience. Feb, 2009 | Pubmed ID: 19172163 BAC Transgenesis in Human Embryonic Stem Cells As a Novel Tool to Define the Human Neural Lineage Stem Cells (Dayton, Ohio). Mar, 2009 | Pubmed ID: 19074416 Parthenogenetic Dopamine Neurons from Primate Embryonic Stem Cells Restore Function in Experimental Parkinson's Disease Brain : a Journal of Neurology. Aug, 2008 | Pubmed ID: 18669499 High-throughput Screening Assay for the Identification of Compounds Regulating Self-renewal and Differentiation in Human Embryonic Stem Cells Cell Stem Cell. Jun, 2008 | Pubmed ID: 18522853 Therapeutic Cloning in Individual Parkinsonian Mice Nature Medicine. Apr, 2008 | Pubmed ID: 18376409 Human ES Cell-derived Neural Rosettes Reveal a Functionally Distinct Early Neural Stem Cell Stage Genes & Development. Jan, 2008 | Pubmed ID: 18198334 Isolation and Directed Differentiation of Neural Crest Stem Cells Derived from Human Embryonic Stem Cells Nature Biotechnology. Dec, 2007 | Pubmed ID: 18037878 Optical Bioluminescence Imaging of Human ES Cell Progeny in the Rodent CNS Journal of Neurochemistry. Sep, 2007 | Pubmed ID: 17555555 Directed Differentiation and Transplantation of Human Embryonic Stem Cell-derived Motoneurons Stem Cells (Dayton, Ohio). Aug, 2007 | Pubmed ID: 17478583 Derivation of Engraftable Skeletal Myoblasts from Human Embryonic Stem Cells Nature Medicine. May, 2007 | Pubmed ID: 17417652 Constitutive Gene Expression Predisposes Morphogen-mediated Cell Fate Responses of NT2/D1 and 27X-1 Human Embryonal Carcinoma Cells Stem Cells (Dayton, Ohio). Mar, 2007 | Pubmed ID: 17138961 Embryonic Stem Cell-derived Neurons Form Functional Networks in Vitro Stem Cells (Dayton, Ohio). Mar, 2007 | Pubmed ID: 17110621 Production of Green Fluorescent Protein Transgenic Embryonic Stem Cells Using the GENSAT Bacterial Artificial Chromosome Library Stem Cells (Dayton, Ohio). Jan, 2007 | Pubmed ID: 16990587 Mesenchymal Cells Methods in Enzymology. 2006 | Pubmed ID: 17141037 Acquisition of in Vitro and in Vivo Functionality of Nurr1-induced Dopamine Neurons FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2006 | Pubmed ID: 17077287 Transplanted Dopamine Neurons Derived from Primate ES Cells Preferentially Innervate DARPP-32 Striatal Progenitors Within the Graft The European Journal of Neuroscience. Oct, 2006 | Pubmed ID: 17067292 Derivation of Multipotent Mesenchymal Precursors from Human Embryonic Stem Cells PLoS Medicine. Jun, 2005 | Pubmed ID: 15971941 Long-term Survival of Dopamine Neurons Derived from Parthenogenetic Primate Embryonic Stem Cells (cyno-1) After Transplantation Stem Cells (Dayton, Ohio). Aug, 2005 | Pubmed ID: 15941857 Migration and Differentiation of Neural Precursors Derived from Human Embryonic Stem Cells in the Rat Brain Nature Biotechnology. May, 2005 | Pubmed ID: 15852001 Transcriptional Program of Bone Morphogenetic Protein-2-induced Epithelial and Smooth Muscle Differentiation of Pluripotent Human Embryonal Carcinoma Cells Functional & Integrative Genomics. Apr, 2005 | Pubmed ID: 15690164 Derivation of Midbrain Dopamine Neurons from Human Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15310843 Enhanced in Vitro Midbrain Dopamine Neuron Differentiation, Dopaminergic Function, Neurite Outgrowth, and 1-methyl-4-phenylpyridium Resistance in Mouse Embryonic Stem Cells Overexpressing Bcl-XL The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2004 | Pubmed ID: 14749429 Nonhuman Primate Parthenogenetic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 14504386 Neural Subtype Specification of Fertilization and Nuclear Transfer Embryonic Stem Cells and Application in Parkinsonian Mice Nature Biotechnology. Oct, 2003 | Pubmed ID: 14502203 Making and Repairing the Mammalian Brain--in Vitro Production of Dopaminergic Neurons Seminars in Cell & Developmental Biology. Jun, 2003 | Pubmed ID: 12948353 Neural Transplantation for the Treatment of Parkinson's Disease Lancet Neurology. Jul, 2003 | Pubmed ID: 12849125 Dopaminergic Neuronal Differentiation from Rat Embryonic Neural Precursors by Nurr1 Overexpression Journal of Neurochemistry. Jun, 2003 | Pubmed ID: 12787064 Expression Profiling of Lineage Differentiation in Pluripotential Human Embryonal Carcinoma Cells Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research. Jun, 2002 | Pubmed ID: 12114215 Parthenogenetic Stem Cells in Nonhuman Primates Science (New York, N.Y.). Feb, 2002 | Pubmed ID: 11823632 Derivação sem alimentador de melanócitos a partir de células-tronco pluripotentes humanas Scott J. Callahan1,2, Yvonne Mica3, Lorenz Studer1 1The Center for Stem Cell Biology, Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, 2Cancer Biology and Genetics Program, Gerstner Sloan-Kettering Graduate School, Sloan-Kettering Institute for Cancer Research, 3Thermo Fisher Scientific JoVE 53806 Developmental Biology Derivação sem alimentador de células da crista neural progenitoras pluripotentes humanas de células-tronco Nadja Zeltner1, Fabien G. Lafaille2, Faranak Fattahi1, Lorenz Studer1 1Developmental Biology, Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, 2St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University JoVE 51609 Neuroscience
Derivação sem alimentador de melanócitos a partir de células-tronco pluripotentes humanas Scott J. Callahan1,2, Yvonne Mica3, Lorenz Studer1 1The Center for Stem Cell Biology, Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, 2Cancer Biology and Genetics Program, Gerstner Sloan-Kettering Graduate School, Sloan-Kettering Institute for Cancer Research, 3Thermo Fisher Scientific JoVE 53806 Developmental Biology
Derivação sem alimentador de células da crista neural progenitoras pluripotentes humanas de células-tronco Nadja Zeltner1, Fabien G. Lafaille2, Faranak Fattahi1, Lorenz Studer1 1Developmental Biology, Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, 2St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University JoVE 51609 Neuroscience
