Lucilia Saraiva

Publications

• Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones As Potential P53-Activating Agents
  Molecules (Basel, Switzerland). May, 2019  |   Pubmed ID: 31121972
• Comparison Study of Different Extracts of , and the Rare (Lamiaceae): Chemical Characterization, Antioxidant, Antimicrobial and Cytotoxic Activities
  Biomolecules. May, 2019  |   Pubmed ID: 31072074
• New Inhibitor of the TAp73 Interaction with MDM2 and Mutant P53 with Promising Antitumor Activity Against Neuroblastoma
  Cancer Letters. Apr, 2019  |   Pubmed ID: 30664963
• New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation
  Molecules (Basel, Switzerland). Dec, 2018  |   Pubmed ID: 30602686
• Improving Anticancer Activity Towards Colon Cancer Cells with a New P53-activating Agent
  British Journal of Pharmacology. 10, 2018  |   Pubmed ID: 30076608
• Targeting the MDM2-p53 Protein-protein Interaction with Prenylchalcones: Synthesis of a Small Library and Evaluation of Potential Antitumor Activity
  European Journal of Medicinal Chemistry. Aug, 2018  |   Pubmed ID: 30041135
• The Crystal Structure of the R280K Mutant of Human P53 Explains the Loss of DNA Binding
  International Journal of Molecular Sciences. Apr, 2018  |   Pubmed ID: 29652801
• P53 and Glucose Metabolism: an Orchestra to Be Directed in Cancer Therapy
  Pharmacological Research. 05, 2018  |   Pubmed ID: 29580896
• Discovery of a Small-molecule Protein Kinase Cδ-selective Activator with Promising Application in Colon Cancer Therapy
  Cell Death & Disease. 01, 2018  |   Pubmed ID: 29348560
• Medicinal Chemistry Strategies to Disrupt the P53-MDM2/MDMX Interaction
  Medicinal Research Reviews. 09, 2016  |   Pubmed ID: 27302609
• P53 Family Interactions and Yeast: Together in Anticancer Therapy
  Drug Discovery Today. Apr, 2016  |   Pubmed ID: 26891980
• Enhanced Cytotoxicity of Prenylated Chalcone Against Tumour Cells Via Disruption of the P53-MDM2 Interaction
  Life Sciences. Dec, 2015  |   Pubmed ID: 26475964
• Chronological Aging in Conidia of Pathogenic Aspergillus: Comparison Between Species
  Journal of Microbiological Methods. Nov, 2015  |   Pubmed ID: 26341609
• A Tryptophanol-derived Oxazolopiperidone Lactam is Cytotoxic Against Tumors Via Inhibition of P53 Interaction with Murine Double Minute Proteins
  Pharmacological Research. May-Jun, 2015  |   Pubmed ID: 25814188
• A Yeast Model of the Parkinson's Disease-associated Protein Parkin
  Experimental Cell Research. Apr, 2015  |   Pubmed ID: 25728007
• Oxazoloisoindolinones with in Vitro Antitumor Activity Selectively Activate a P53-pathway Through Potential Inhibition of the P53-MDM2 Interaction
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jan, 2015  |   Pubmed ID: 25312347
• Studying P53 Family Proteins in Yeast: Induction of Autophagic Cell Death and Modulation by Interactors and Small Molecules
  Experimental Cell Research. Jan, 2015  |   Pubmed ID: 25265062
• Microglia P2Y₆ Receptors Mediate Nitric Oxide Release and Astrocyte Apoptosis
  Journal of Neuroinflammation. Sep, 2014  |   Pubmed ID: 25178395
• LRRK2, but Not Pathogenic Mutants, Protects Against H2O2 Stress Depending on Mitochondrial Function and Endocytosis in a Yeast Model
  Biochimica Et Biophysica Acta. Jun, 2014  |   Pubmed ID: 24576675
• Potential Small-molecule Activators of Caspase-7 Identified Using Yeast-based Caspase-3 and -7 Screening Assays
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Apr, 2014  |   Pubmed ID: 24398107
• SNaPaer: a Practical Single Nucleotide Polymorphism Multiplex Assay for Genotyping of Pseudomonas Aeruginosa
  PloS One. 2013  |   Pubmed ID: 23776608
• Interference of Aging Media on the Assessment of Yeast Chronological Life Span by Propidium Iodide Staining
  Folia Microbiologica. Jan, 2013  |   Pubmed ID: 22828896
• Contribution of Yeast Models to Neurodegeneration Research
  Journal of Biomedicine & Biotechnology. 2012  |   Pubmed ID: 22910375
• Contribution of Yeast and Plant Research for Improving Human Health
  Journal of Biomedicine & Biotechnology. 2012  |   Pubmed ID: 22851885
• Endocytosis Inhibition During H2O2-induced Apoptosis in Yeast
  FEMS Yeast Research. Nov, 2012  |   Pubmed ID: 22741558
• New Therapeutic Strategies for Cancer and Neurodegeneration Emerging from Yeast Cell-based Systems
  Current Pharmaceutical Design. 2012  |   Pubmed ID: 22650181
• New Insights into Cancer-related Proteins Provided by the Yeast Model
  The FEBS Journal. Mar, 2012  |   Pubmed ID: 22239976