Lucy Shapiro Department of Developmental Biology Stanford University School of Medicine Biography Publications Institution JoVE Articles Lucy Shapiro has not added a biography. If you are Lucy Shapiro and would like to personalize this page please email our Author Liaison for assistance. Publications The Global Regulatory Architecture of Transcription During the Caulobacter Cell Cycle PLoS Genetics. Jan, 2015 | Pubmed ID: 25569173 Cell Fate Regulation Governed by a Repurposed Bacterial Histidine Kinase PLoS Biology. Oct, 2014 | Pubmed ID: 25349992 Replication Initiator DnaA Binds at the Caulobacter Centromere and Enables Chromosome Segregation Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25349407 The Coding and Noncoding Architecture of the Caulobacter Crescentus Genome PLoS Genetics. Jul, 2014 | Pubmed ID: 25078267 ClpXP and ClpAP Proteolytic Activity on Divisome Substrates is Differentially Regulated Following the Caulobacter Asymmetric Cell Division Molecular Microbiology. Sep, 2014 | Pubmed ID: 24989075 Bacterial Scaffold Directs Pole-specific Centromere Segregation Proceedings of the National Academy of Sciences of the United States of America. May, 2014 | Pubmed ID: 24778223 The Functions of DNA Methylation by CcrM in Caulobacter Crescentus: a Global Approach Nucleic Acids Research. Apr, 2014 | Pubmed ID: 24398711 Global Methylation State at Base-pair Resolution of the Caulobacter Genome Throughout the Cell Cycle Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013 | Pubmed ID: 24218615 Oligomerization and Higher-order Assembly Contribute to Sub-cellular Localization of a Bacterial Scaffold Molecular Microbiology. Nov, 2013 | Pubmed ID: 24102805 Branched Signal Wiring of an Essential Bacterial Cell-cycle Phosphotransfer Protein Structure (London, England : 1993). Sep, 2013 | Pubmed ID: 23932593 Retrospective. Francois Jacob (1920-2013) Science (New York, N.Y.). May, 2013 | Pubmed ID: 23704565 Quantitative Multicolor Subdiffraction Imaging of Bacterial Protein Ultrastructures in Three Dimensions Nano Letters. Mar, 2013 | Pubmed ID: 23414562 Caulobacter Chromosome in Vivo Configuration Matches Model Predictions for a Supercoiled Polymer in a Cell-like Confinement Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23319648 Chromosome Architecture is a Key Element of Bacterial Cellular Organization Cellular Microbiology. Jan, 2013 | Pubmed ID: 23078580 Life in a Three-dimensional Grid The Journal of Biological Chemistry. Nov, 2012 | Pubmed ID: 23007401 Osmolality-dependent Relocation of Penicillin-binding Protein PBP2 to the Division Site in Caulobacter Crescentus Journal of Bacteriology. Jun, 2012 | Pubmed ID: 22505677 Three-dimensional Super-resolution Imaging of the Midplane Protein FtsZ in Live Caulobacter Crescentus Cells Using Astigmatism Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Mar, 2012 | Pubmed ID: 22262316 Structure of the Pilus Assembly Protein TadZ from Eubacterium Rectale: Implications for Polar Localization Molecular Microbiology. Feb, 2012 | Pubmed ID: 22211578 Three-dimensional Superresolution Colocalization of Intracellular Protein Superstructures and the Cell Surface in Live Caulobacter Crescentus Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22031697 The Three-dimensional Architecture of a Bacterial Genome and Its Alteration by Genetic Perturbation Molecular Cell. Oct, 2011 | Pubmed ID: 22017872 An SMC ATPase Mutant Disrupts Chromosome Segregation in Caulobacter Molecular Microbiology. Dec, 2011 | Pubmed ID: 21923769 Exploring Protein Superstructures and Dynamics in Live Bacterial Cells Using Single-molecule and Superresolution Imaging Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21909887 The Essential Genome of a Bacterium Molecular Systems Biology. 2011 | Pubmed ID: 21878915 Fifty Years After Jacob and Monod: What Are the Unanswered Questions in Molecular Biology? Molecular Cell. May, 2011 | Pubmed ID: 21748867 Mutations in the Nucleotide Binding Pocket of MreB Can Alter Cell Curvature and Polar Morphology in Caulobacter Molecular Microbiology. Jul, 2011 | Pubmed ID: 21564339 Assembly of the Caulobacter Cell Division Machine Molecular Microbiology. Jun, 2011 | Pubmed ID: 21542856 Regulatory Response to Carbon Starvation in Caulobacter Crescentus PloS One. 2011 | Pubmed ID: 21494595 Super-resolution Imaging of the Nucleoid-associated Protein HU in Caulobacter Crescentus Biophysical Journal. Apr, 2011 | Pubmed ID: 21463569 The Architecture and Conservation Pattern of Whole-cell Control Circuitry Journal of Molecular Biology. May, 2011 | Pubmed ID: 21371478 Bacterial Polarity Current Opinion in Cell Biology. Feb, 2011 | Pubmed ID: 21095111 An Essential Transcription Factor, SciP, Enhances Robustness of Caulobacter Cell Cycle Regulation Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20956288 Initiating Bacterial Mitosis: Understanding the Mechanism of ParA-mediated Chromosome Segregation Cell Cycle (Georgetown, Tex.). Oct, 2010 | Pubmed ID: 20948303 Superresolution Imaging of Targeted Proteins in Fixed and Living Cells Using Photoactivatable Organic Fluorophores Journal of the American Chemical Society. Nov, 2010 | Pubmed ID: 20936809 Imaging-based Identification of a Critical Regulator of FtsZ Protofilament Curvature in Caulobacter Molecular Cell. Sep, 2010 | Pubmed ID: 20864042 The Caulobacter Tol-Pal Complex is Essential for Outer Membrane Integrity and the Positioning of a Polar Localization Factor Journal of Bacteriology. Oct, 2010 | Pubmed ID: 20693330 A Spindle-like Apparatus Guides Bacterial Chromosome Segregation Nature Cell Biology. Aug, 2010 | Pubmed ID: 20657594 CrfA, a Small Noncoding RNA Regulator of Adaptation to Carbon Starvation in Caulobacter Crescentus Journal of Bacteriology. Sep, 2010 | Pubmed ID: 20601471 Polar Remodeling and Histidine Kinase Activation, Which is Essential for Caulobacter Cell Cycle Progression, Are Dependent on DNA Replication Initiation Journal of Bacteriology. Aug, 2010 | Pubmed ID: 20525830 DipM Links Peptidoglycan Remodelling to Outer Membrane Organization in Caulobacter Molecular Microbiology. Jul, 2010 | Pubmed ID: 20497504 Cell Pole-specific Activation of a Critical Bacterial Cell Cycle Kinase Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20351295 Bacterial Chromosome Organization and Segregation Cold Spring Harbor Perspectives in Biology. Feb, 2010 | Pubmed ID: 20182613 High-throughput Identification of Protein Localization Dependency Networks Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20176934 Caulobacter PopZ Forms a Polar Subdomain Dictating Sequential Changes in Pole Composition and Function Molecular Microbiology. Apr, 2010 | Pubmed ID: 20149103 System-level Design of Bacterial Cell Cycle Control FEBS Letters. Dec, 2009 | Pubmed ID: 19766635 Feedback Control of DnaA-mediated Replication Initiation by Replisome-associated HdaA Protein in Caulobacter Journal of Bacteriology. Sep, 2009 | Pubmed ID: 19633089 A Bacterial Control Circuit Integrates Polar Localization and Proteolysis of Key Regulatory Proteins with a Phospho-signaling Cascade Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18946044 Caulobacter Requires a Dedicated Mechanism to Initiate Chromosome Segregation Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18824683 A Polymeric Protein Anchors the Chromosomal Origin/ParB Complex at a Bacterial Cell Pole Cell. Sep, 2008 | Pubmed ID: 18805088 Super-resolution Imaging in Live Caulobacter Crescentus Cells Using Photoswitchable EYFP Nature Methods. Nov, 2008 | Pubmed ID: 18794860 SpoT Regulates DnaA Stability and Initiation of DNA Replication in Carbon-starved Caulobacter Crescentus Journal of Bacteriology. Oct, 2008 | Pubmed ID: 18723629 Architecture and Inherent Robustness of a Bacterial Cell-cycle Control System Proceedings of the National Academy of Sciences of the United States of America. Aug, 2008 | Pubmed ID: 18685108 Small Non-coding RNAs in Caulobacter Crescentus Molecular Microbiology. May, 2008 | Pubmed ID: 18373523 Getting Organized--how Bacterial Cells Move Proteins and DNA Nature Reviews. Microbiology. Jan, 2008 | Pubmed ID: 18059290 Systems Biology of Caulobacter Annual Review of Genetics. 2007 | Pubmed ID: 18076330 A Comprehensive Set of Plasmids for Vanillate- and Xylose-inducible Gene Expression in Caulobacter Crescentus Nucleic Acids Research. 2007 | Pubmed ID: 17959646 A DNA Methylation Ratchet Governs Progression Through a Bacterial Cell Cycle Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17942674 Cell Cycle Regulation in Caulobacter: Location, Location, Location Journal of Cell Science. Oct, 2007 | Pubmed ID: 17928306 Caulobacter Crescentus As a Whole-cell Uranium Biosensor Applied and Environmental Microbiology. Dec, 2007 | Pubmed ID: 17905881 Spatial Complexity and Control of a Bacterial Cell Cycle Current Opinion in Biotechnology. Aug, 2007 | Pubmed ID: 17709236 An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping TRNA in the Editing Site Science (New York, N.Y.). Jun, 2007 | Pubmed ID: 17588934 The Push and Pull of the Bacterial Cytoskeleton Trends in Cell Biology. May, 2007 | Pubmed ID: 17434308 High-throughput Identification of Transcription Start Sites, Conserved Promoter Motifs and Predicted Regulons Nature Biotechnology. May, 2007 | Pubmed ID: 17401361 Chromosome Organization and Segregation in Bacteria Journal of Structural Biology. Nov, 2006 | Pubmed ID: 16860572 MipZ, a Spatial Regulator Coordinating Chromosome Segregation with Cell Division in Caulobacter Cell. Jul, 2006 | Pubmed ID: 16839883 Single Molecules of the Bacterial Actin MreB Undergo Directed Treadmilling Motion in Caulobacter Crescentus Proceedings of the National Academy of Sciences of the United States of America. Jul, 2006 | Pubmed ID: 16829583 A Phospho-signaling Pathway Controls the Localization and Activity of a Protease Complex Critical for Bacterial Cell Cycle Progression Proceedings of the National Academy of Sciences of the United States of America. Jul, 2006 | Pubmed ID: 16829582 A Dynamically Localized Protease Complex and a Polar Specificity Factor Control a Cell Cycle Master Regulator Cell. Feb, 2006 | Pubmed ID: 16469700 The Bifunctional FtsK Protein Mediates Chromosome Partitioning and Cell Division in Caulobacter Journal of Bacteriology. Feb, 2006 | Pubmed ID: 16452433 DnaA Couples DNA Replication and the Expression of Two Cell Cycle Master Regulators The EMBO Journal. Jan, 2006 | Pubmed ID: 16395331 Cytokinesis Signals Truncation of the PodJ Polarity Factor by a Cell Cycle-regulated Protease The EMBO Journal. Jan, 2006 | Pubmed ID: 16395329 Two Independent Spiral Structures Control Cell Shape in Caulobacter Proceedings of the National Academy of Sciences of the United States of America. Dec, 2005 | Pubmed ID: 16344481 DnaA Coordinates Replication Initiation and Cell Cycle Transcription in Caulobacter Crescentus Molecular Microbiology. Dec, 2005 | Pubmed ID: 16313620 Identification of Borinic Esters As Inhibitors of Bacterial Cell Growth and Bacterial Methyltransferases, CcrM and MenH Journal of Medicinal Chemistry. Nov, 2005 | Pubmed ID: 16279806 The Bacterial Nucleoid: a Highly Organized and Dynamic Structure Journal of Cellular Biochemistry. Oct, 2005 | Pubmed ID: 15988757 Conserved Modular Design of an Oxygen Sensory/signaling Network with Species-specific Output Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15911751 The Choreographed Dynamics of Bacterial Chromosomes Trends in Microbiology. May, 2005 | Pubmed ID: 15866039 The Structure and Function of the Bacterial Chromosome Current Opinion in Genetics & Development. Apr, 2005 | Pubmed ID: 15797198 An Open Letter to Elias Zerhouni Science (New York, N.Y.). Mar, 2005 | Pubmed ID: 15746409 MreB Actin-mediated Segregation of a Specific Region of a Bacterial Chromosome Cell. Feb, 2005 | Pubmed ID: 15707892 A Membrane Metalloprotease Participates in the Sequential Degradation of a Caulobacter Polarity Determinant Molecular Microbiology. Feb, 2005 | Pubmed ID: 15686556 Spatial Complexity of Mechanisms Controlling a Bacterial Cell Cycle Current Opinion in Microbiology. Dec, 2004 | Pubmed ID: 15556028 A Genetic Oscillator and the Regulation of Cell Cycle Progression in Caulobacter Crescentus Cell Cycle (Georgetown, Tex.). Oct, 2004 | Pubmed ID: 15467452 The Topoisomerase IV ParC Subunit Colocalizes with the Caulobacter Replisome and is Required for Polar Localization of Replication Origins Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15178756 Rapid and Sequential Movement of Individual Chromosomal Loci to Specific Subcellular Locations During Bacterial DNA Replication Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15178755 An Actin-like Gene Can Determine Cell Polarity in Bacteria Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15159537 Recruitment of a Cytoplasmic Response Regulator to the Cell Pole is Linked to Its Cell Cycle-regulated Proteolysis Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15123835 Oscillating Global Regulators Control the Genetic Circuit Driving a Bacterial Cell Cycle Science (New York, N.Y.). May, 2004 | Pubmed ID: 15087506 Codon Usage Between Genomes is Constrained by Genome-wide Mutational Processes Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14990797 A Bacterial Cell-cycle Regulatory Network Operating in Time and Space Science (New York, N.Y.). Sep, 2003 | Pubmed ID: 14512618 Identification of Long Intergenic Repeat Sequences Associated with DNA Methylation Sites in Caulobacter Crescentus and Other Alpha-proteobacteria Journal of Bacteriology. Aug, 2003 | Pubmed ID: 12897020 A Lytic Transglycosylase Homologue, PleA, is Required for the Assembly of Pili and the Flagellum at the Caulobacter Crescentus Cell Pole Molecular Microbiology. Jul, 2003 | Pubmed ID: 12828633 Fluorescence Bleaching Reveals Asymmetric Compartment Formation Prior to Cell Division in Caulobacter Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12824468 Bacterial Cell Division Spirals into Control Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003 | Pubmed ID: 12810947 Polar Localization of Replicon Origins in the Multipartite Genomes of Agrobacterium Tumefaciens and Sinorhizobium Meliloti Journal of Bacteriology. Jun, 2003 | Pubmed ID: 12754237 Cell-cycle-regulated Expression and Subcellular Localization of the Caulobacter Crescentus SMC Chromosome Structural Protein Journal of Bacteriology. May, 2003 | Pubmed ID: 12730166 Temporal and Spatial Regulation in Prokaryotic Cell Cycle Progression and Development Annual Review of Biochemistry. 2003 | Pubmed ID: 12651741 TmRNA in Caulobacter Crescentus is Cell Cycle Regulated by Temporally Controlled Transcription and RNA Degradation Journal of Bacteriology. Mar, 2003 | Pubmed ID: 12618446 Functions of the CckA Histidine Kinase in Caulobacter Cell Cycle Control Molecular Microbiology. Mar, 2003 | Pubmed ID: 12603734 TmRNA is Required for Correct Timing of DNA Replication in Caulobacter Crescentus Journal of Bacteriology. Jan, 2003 | Pubmed ID: 12511504 Generating and Exploiting Polarity in Bacteria Science (New York, N.Y.). Dec, 2002 | Pubmed ID: 12471245 The CtrA Response Regulator Essential for Caulobacter Crescentus Cell-cycle Progression Requires a Bipartite Degradation Signal for Temporally Controlled Proteolysis Journal of Molecular Biology. Nov, 2002 | Pubmed ID: 12445780 Identification of a Localization Factor for the Polar Positioning of Bacterial Structural and Regulatory Proteins Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12370432 A Signal Transduction Protein Cues Proteolytic Events Critical to Caulobacter Cell Cycle Progression Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12237413 DNA Methylation Affects the Cell Cycle Transcription of the CtrA Global Regulator in Caulobacter The EMBO Journal. Sep, 2002 | Pubmed ID: 12234936 A Dynamically Localized Histidine Kinase Controls the Asymmetric Distribution of Polar Pili Proteins The EMBO Journal. Sep, 2002 | Pubmed ID: 12198144 Control of Chromosome Replication in Caulobacter Crescentus Annual Review of Microbiology. 2002 | Pubmed ID: 12142494 Dynamic Localization of Proteins and DNA During a Bacterial Cell Cycle Nature Reviews. Molecular Cell Biology. Mar, 2002 | Pubmed ID: 11994737 Genes Directly Controlled by CtrA, a Master Regulator of the Caulobacter Cell Cycle Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002 | Pubmed ID: 11930012 تزامن Jared M. Schrader1, Lucy Shapiro1 1Department of Developmental Biology, Stanford University School of Medicine Biology
تزامن Jared M. Schrader1, Lucy Shapiro1 1Department of Developmental Biology, Stanford University School of Medicine Biology
