Luis A. Pardo

Publications

• New Structures and Gating of Voltage-Dependent Potassium (Kv) Channels and Their Relatives: A Multi-Domain and Dynamic Question
  International Journal of Molecular Sciences. Jan, 2019  |   Pubmed ID: 30634573
• Synthesis of Novel Purpurealidin Analogs and Evaluation of Their Effect on the Cancer-relevant Potassium Channel KV10.1
  PloS One. 2017  |   Pubmed ID: 29220359
• APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel K10.1
  Marine Drugs. Sep, 2017  |   Pubmed ID: 28902151
• Alternating PH Landscapes Shape Epithelial Cancer Initiation and Progression: Focus on Pancreatic Cancer
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. 06, 2017  |   Pubmed ID: 28440551
• A New Mechanism of Voltage-dependent Gating Exposed by K10.1 Channels Interrupted Between Voltage Sensor and Pore
  The Journal of General Physiology. May, 2017  |   Pubmed ID: 28360219
• SK3 Channel Overexpression in Mice Causes Hippocampal Shrinkage Associated with Cognitive Impairments
  Molecular Neurobiology. 03, 2017  |   Pubmed ID: 26803493
• In Vivo Imaging of Tumour Xenografts with an Antibody Targeting the Potassium Channel K10.1
  European Biophysics Journal : EBJ. Oct, 2016  |   Pubmed ID: 27444284
• Ion Channels, Transporters and Cancer ("INCA2015"): an International Meeting in Honor of Prof. Dr. Walter Stühmer
  European Biophysics Journal : EBJ. Oct, 2016  |   Pubmed ID: 27435254
• Guiding TRAIL to Cancer Cells Through Kv10.1 Potassium Channel Overcomes Resistance to Doxorubicin
  European Biophysics Journal : EBJ. Oct, 2016  |   Pubmed ID: 27350552
• Cyclic Expression of the Voltage-gated Potassium Channel KV10.1 Promotes Disassembly of the Primary Cilium
  EMBO Reports. 05, 2016  |   Pubmed ID: 27113750
• Periodic Expression of Kv10.1 Driven by PRb/E2F1 Contributes to G2/M Progression of Cancer and Non-transformed Cells
  Cell Cycle (Georgetown, Tex.). 2016  |   Pubmed ID: 27029528
• Kv10.1 K(+) Channel: from Physiology to Cancer
  Pflugers Archiv : European Journal of Physiology. 05, 2016  |   Pubmed ID: 26743871
• Analysis of the Expression of Kv10.1 Potassium Channel in Patients with Brain Metastases and Glioblastoma Multiforme: Impact on Survival
  BMC Cancer. Nov, 2015  |   Pubmed ID: 26530050
• Alternatively Spliced Isoforms of KV10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes
  The Journal of Biological Chemistry. Dec, 2015  |   Pubmed ID: 26518875
• CD133 Expression Is Not Synonymous to Immunoreactivity for AC133 and Fluctuates Throughout the Cell Cycle in Glioma Stem-Like Cells
  PloS One. 2015  |   Pubmed ID: 26086074
• Voltage-dependent Gating of KCNH Potassium Channels Lacking a Covalent Link Between Voltage-sensing and Pore Domains
  Nature Communications. Mar, 2015  |   Pubmed ID: 25818916
• KV 10.1 Opposes Activity-dependent Increase in Ca²⁺ Influx into the Presynaptic Terminal of the Parallel Fibre-Purkinje Cell Synapse
  The Journal of Physiology. 01, 2015  |   Pubmed ID: 25556795
• Potassium Channels in Cell Cycle and Cell Proliferation
  Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Mar, 2014  |   Pubmed ID: 24493742
• The Roles of K(+) Channels in Cancer
  Nature Reviews. Cancer. Jan, 2014  |   Pubmed ID: 24336491
• KV10.1 K(+)-channel Plasma Membrane Discrete Domain Partitioning and Its Functional Correlation in Neurons
  Biochimica Et Biophysica Acta. Mar, 2014  |   Pubmed ID: 24269539
• PIST (GOPC) Modulates the Oncogenic Voltage-gated Potassium Channel KV10.1
  Frontiers in Physiology. 2013  |   Pubmed ID: 23966943
• Human Glioma-initiating Cells Show a Distinct Immature Phenotype Resembling but Not Identical to NG2 Glia
  Journal of Neuropathology and Experimental Neurology. Apr, 2013  |   Pubmed ID: 23481707
• Behavioural and Functional Characterization of Kv10.1 (Eag1) Knockout Mice
  Human Molecular Genetics. Jun, 2013  |   Pubmed ID: 23424202
• TRPM8 Ion Channels Differentially Modulate Proliferation and Cell Cycle Distribution of Normal and Cancer Prostate Cells
  PloS One. 2012  |   Pubmed ID: 23251635
• Cortactin Controls Surface Expression of the Voltage-gated Potassium Channel K(V)10.1
  The Journal of Biological Chemistry. Dec, 2012  |   Pubmed ID: 23144454
• Physical and Functional Interaction of KV10.1 with Rabaptin-5 Impacts Ion Channel Trafficking
  FEBS Letters. Sep, 2012  |   Pubmed ID: 22841712
• Approaches Targeting K(V)10.1 Open a Novel Window for Cancer Diagnosis and Therapy
  Current Medicinal Chemistry. 2012  |   Pubmed ID: 22204340
• Rapid Internalization of the Oncogenic K+ Channel K(V)10.1
  PloS One. 2011  |   Pubmed ID: 22022602
• Functional K(v)10.1 Channels Localize to the Inner Nuclear Membrane
  PloS One. 2011  |   Pubmed ID: 21559285
• A CAG Repeat Polymorphism of KCNN3 Predicts SK3 Channel Function and Cognitive Performance in Schizophrenia
  EMBO Molecular Medicine. Jun, 2011  |   Pubmed ID: 21433290
• K(+) Channels As Therapeutic Targets in Oncology
  Future Medicinal Chemistry. May, 2010  |   Pubmed ID: 21426201
• Characterization of Eag1 Channel Lateral Mobility in Rat Hippocampal Cultures by Single-particle-tracking with Quantum Dots
  PloS One. 2010  |   Pubmed ID: 20111597
• The Potassium Channel Ether à Go-go is a Novel Prognostic Factor with Functional Relevance in Acute Myeloid Leukemia
  Molecular Cancer. Jan, 2010  |   Pubmed ID: 20105281
• The Voltage Dependence of HEag Currents is Not Determined Solely by Membrane-spanning Domains
  European Biophysics Journal : EBJ. Mar, 2009  |   Pubmed ID: 18379771
• Eag1 Expression Interferes with Hypoxia Homeostasis and Induces Angiogenesis in Tumors
  The Journal of Biological Chemistry. Dec, 2008  |   Pubmed ID: 18927085
• Eag1 As a Cancer Target
  Expert Opinion on Therapeutic Targets. Jul, 2008  |   Pubmed ID: 18554152
• Pattern of Axonal Injury in Murine Myelin Oligodendrocyte Glycoprotein Induced Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis
  Neurobiology of Disease. May, 2008  |   Pubmed ID: 18342527
• Eag1: an Emerging Oncological Target
  Cancer Research. Mar, 2008  |   Pubmed ID: 18339837
• Monoclonal Antibody Blockade of the Human Eag1 Potassium Channel Function Exerts Antitumor Activity
  Cancer Research. Aug, 2007  |   Pubmed ID: 17671204
• Re-expression of a Developmentally Restricted Potassium Channel in Autoimmune Demyelination: Kv1.4 is Implicated in Oligodendroglial Proliferation
  The American Journal of Pathology. Aug, 2007  |   Pubmed ID: 17600124
• Different Relevance of Inactivation and F468 Residue in the Mechanisms of HEag1 Channel Blockage by Astemizole, Imipramine and Dofetilide
  FEBS Letters. Sep, 2006  |   Pubmed ID: 16949586
• Silencing the Activity and Proliferative Properties of the Human EagI Potassium Channel by RNA Interference
  The Journal of Biological Chemistry. May, 2006  |   Pubmed ID: 16537547
• Role of Voltage-gated Potassium Channels in Cancer
  The Journal of Membrane Biology. Jun, 2005  |   Pubmed ID: 16362499