Luis F. Santana Department of Physiology & Biophysics University of Washington Biography Publications Institution JoVE Articles Luis F. Santana has not added a biography. If you are Luis F. Santana and would like to personalize this page please email our Author Liaison for assistance. Publications Ca2+ Signaling Amplification by Oligomerization of L-type Cav1.2 Channels Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22307641 Dynamic Changes in Sarcoplasmic Reticulum Structure in Ventricular Myocytes Journal of Biomedicine & Biotechnology. 2011 | Pubmed ID: 22131804 An Entirely Specific Type I A-kinase Anchoring Protein That Can Sequester Two Molecules of Protein Kinase A at Mitochondria Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22084075 Relationship Between Ca2+ Sparklets and Sarcoplasmic Reticulum Ca2+ Load and Release in Rat Cerebral Arterial Smooth Muscle American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2011 | Pubmed ID: 21984539 Restoration of Normal L-type Ca2+ Channel Function During Timothy Syndrome by Ablation of an Anchoring Protein Circulation Research. Jul, 2011 | Pubmed ID: 21700933 Mitochondrial Targeted Antioxidant Peptide Ameliorates Hypertensive Cardiomyopathy Journal of the American College of Cardiology. Jun, 2011 | Pubmed ID: 21620606 Mitochondrial Oxidative Stress Mediates Angiotensin II-induced Cardiac Hypertrophy and Galphaq Overexpression-induced Heart Failure Circulation Research. Apr, 2011 | Pubmed ID: 21311045 Eosinophil Cysteinyl Leukotriene Synthesis Mediated by Exogenous Secreted Phospholipase A2 Group X The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20974857 How Does the Shape of the Cardiac Action Potential Control Calcium Signaling and Contraction in the Heart? Journal of Molecular and Cellular Cardiology. Dec, 2010 | Pubmed ID: 20850450 Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 with a Subpopulation of L-type Calcium Channels Circulation Research. Sep, 2010 | Pubmed ID: 20671242 Natural Inequalities: Why Some L-type Ca2+ Channels Work Harder Than Others The Journal of General Physiology. Aug, 2010 | Pubmed ID: 20660657 Phosphodiesterase 8A (PDE8A) Regulates Excitation-contraction Coupling in Ventricular Myocytes Journal of Molecular and Cellular Cardiology. Aug, 2010 | Pubmed ID: 20353794 A-kinase Anchoring Proteins: Getting to the Heart of the Matter Circulation. Mar, 2010 | Pubmed ID: 20231544 Knockout of Na+/Ca2+ Exchanger in Smooth Muscle Attenuates Vasoconstriction and L-type Ca2+ Channel Current and Lowers Blood Pressure American Journal of Physiology. Heart and Circulatory Physiology. May, 2010 | Pubmed ID: 20173044 Increased Coupled Gating of L-type Ca2+ Channels During Hypertension and Timothy Syndrome Circulation Research. Mar, 2010 | Pubmed ID: 20110531 Elevated Ca2+ Sparklet Activity During Acute Hyperglycemia and Diabetes in Cerebral Arterial Smooth Muscle Cells American Journal of Physiology. Cell Physiology. Feb, 2010 | Pubmed ID: 19846755 Myostatin Represses Physiological Hypertrophy of the Heart and Excitation-contraction Coupling The Journal of Physiology. Oct, 2009 | Pubmed ID: 19736304 Molecular and Biophysical Mechanisms of Ca2+ Sparklets in Smooth Muscle Journal of Molecular and Cellular Cardiology. Oct, 2009 | Pubmed ID: 19616004 Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging Circulation. Jun, 2009 | Pubmed ID: 19451351 Local Control of Excitation-contraction Coupling in Human Embryonic Stem Cell-derived Cardiomyocytes PloS One. 2009 | Pubmed ID: 19404384 NFATc3-dependent Loss of I(to) Gradient Across the Left Ventricular Wall During Chronic Beta Adrenergic Stimulation Journal of Molecular and Cellular Cardiology. Feb, 2009 | Pubmed ID: 19027024 The Control of Ca2+ Influx and NFATc3 Signaling in Arterial Smooth Muscle During Hypertension Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18832165 NFAT-dependent Excitation-transcription Coupling in Heart Circulation Research. Sep, 2008 | Pubmed ID: 18818410 Calcium Sparklets in Arterial Smooth Muscle Clinical and Experimental Pharmacology & Physiology. Sep, 2008 | Pubmed ID: 18215181 AKAP150 is Required for Stuttering Persistent Ca2+ Sparklets and Angiotensin II-induced Hypertension Circulation Research. Feb, 2008 | Pubmed ID: 18174462 SMAKing Ca2+ Sparks in Arterial Myocytes The Journal of Physiology. Oct, 2007 | Pubmed ID: 17717006 Ca(v)1.3 Channels Produce Persistent Calcium Sparklets, but Ca(v)1.2 Channels Are Responsible for Sparklets in Mouse Arterial Smooth Muscle American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2007 | Pubmed ID: 17526649 Calcium Sparklets Regulate Local and Global Calcium in Murine Arterial Smooth Muscle The Journal of Physiology. Feb, 2007 | Pubmed ID: 17158168 Activation of NFATc3 Down-regulates the Beta1 Subunit of Large Conductance, Calcium-activated K+ Channels in Arterial Smooth Muscle and Contributes to Hypertension The Journal of Biological Chemistry. Feb, 2007 | Pubmed ID: 17148444 Phosphoinositide 3-kinase Binds to TRPV1 and Mediates NGF-stimulated TRPV1 Trafficking to the Plasma Membrane The Journal of General Physiology. Nov, 2006 | Pubmed ID: 17074976 Mechanisms Underlying Heterogeneous Ca2+ Sparklet Activity in Arterial Smooth Muscle The Journal of General Physiology. Jun, 2006 | Pubmed ID: 16702354 Differential Calcineurin/NFATc3 Activity Contributes to the Ito Transmural Gradient in the Mouse Heart Circulation Research. May, 2006 | Pubmed ID: 16614306 Kv2 Channels Oppose Myogenic Constriction of Rat Cerebral Arteries American Journal of Physiology. Cell Physiology. Aug, 2006 | Pubmed ID: 16571867 On the Loose: Uncaging Ca2+ -induced Ca2+ Release in Smooth Muscle The Journal of General Physiology. Mar, 2006 | Pubmed ID: 16505144 Mechanisms Underlying Variations in Excitation-contraction Coupling Across the Mouse Left Ventricular Free Wall The Journal of Physiology. Apr, 2006 | Pubmed ID: 16423856 Sodium Current and Arrhythmogenesis in Heart Failure Heart Failure Clinics. Jul, 2005 | Pubmed ID: 17386846 Constitutively Active L-type Ca2+ Channels Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005 | Pubmed ID: 16040810 Alterations in Early Action Potential Repolarization Causes Localized Failure of Sarcoplasmic Reticulum Ca2+ Release Circulation Research. Mar, 2005 | Pubmed ID: 15705962 NFATc3 Regulates Kv2.1 Expression in Arterial Smooth Muscle The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15322114 Modulation of the Molecular Composition of Large Conductance, Ca(2+) Activated K(+) Channels in Vascular Smooth Muscle During Hypertension The Journal of Clinical Investigation. Sep, 2003 | Pubmed ID: 12952920 פרופיל תא יחיד תעתיק של cardiomyocytes עכבר למבוגרים James M. Flynn1, Luis F. Santana2, Simon Melov1 1Buck Institute for Research on Aging, 2Department of Physiology & Biophysics, University of Washington JoVE 3302 Biology
פרופיל תא יחיד תעתיק של cardiomyocytes עכבר למבוגרים James M. Flynn1, Luis F. Santana2, Simon Melov1 1Buck Institute for Research on Aging, 2Department of Physiology & Biophysics, University of Washington JoVE 3302 Biology