Luis Martínez-Sobrido Texas Biomedical Research Institute Biography Publications Institution JoVE Articles Luis Martínez-Sobrido has not added a biography. If you are Luis Martínez-Sobrido and would like to personalize this page please email our Author Liaison for assistance. Publications The K18-hACE2 Transgenic Mouse Model Recapitulates Non-Severe and Severe COVID-19 in Response to Infectious Dose of SARS-CoV-2 Virus Journal of Virology. Oct, 2021 | Pubmed ID: 34668775 Natural Selection of H5N1 Avian Influenza A Viruses with Increased PA-X and NS1 Shutoff Activity Viruses. Sep, 2021 | Pubmed ID: 34578340 Analysis of SARS-CoV-2 Infection Dynamic in Vivo Using Reporter-expressing Viruses Proceedings of the National Academy of Sciences of the United States of America. 10, 2021 | Pubmed ID: 34561300 Equine Influenza Virus and Vaccines Viruses. Aug, 2021 | Pubmed ID: 34452521 Immunogenicity and Protective Efficacy of an Intranasal Live-attenuated Vaccine Against SARS-CoV-2 IScience. Sep, 2021 | Pubmed ID: 34368648 A SARS-CoV-2 Nucleocapsid Protein TR-FRET Assay Amenable to High-throughput Screening BioRxiv : the Preprint Server for Biology. Jul, 2021 | Pubmed ID: 34268508 A New Master Donor Virus for the Development of Live-Attenuated Influenza B Virus Vaccines Viruses. 06, 2021 | Pubmed ID: 34208979 Epitope Classification and RBD Binding Properties of Neutralizing Antibodies Against SARS-CoV-2 Variants of Concern Frontiers in Immunology. 2021 | Pubmed ID: 34149735 Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice Journal of Virology. 08, 2021 | Pubmed ID: 34133899 A Metal Ion Orients SARS-CoV-2 MRNA to Ensure Accurate 2'-O Methylation of Its First Nucleotide Nature Communications. 06, 2021 | Pubmed ID: 34078893 Amino Acid Residues Involved in Inhibition of Host Gene Expression by Influenza A/Brevig Mission/1/1918 PA-X Microorganisms. May, 2021 | Pubmed ID: 34065592 Modeling SARS-CoV-2 and Influenza Infections and Antiviral Treatments in Human Lung Epithelial Tissue Equivalents BioRxiv : the Preprint Server for Biology. May, 2021 | Pubmed ID: 34013274 Replication-Competent ΔNS1 Influenza A Viruses Expressing Reporter Genes Viruses. 04, 2021 | Pubmed ID: 33920517 FACT Subunit SUPT16H Associates with BRD4 and Contributes to Silencing of Antiviral Interferon Signaling BioRxiv : the Preprint Server for Biology. Apr, 2021 | Pubmed ID: 33907746 Identification of Amino Acid Residues Required for Inhibition of Host Gene Expression by Influenza A/Viet Nam/1203/2004 H5N1 PA-X Journal of Virology. Apr, 2021 | Pubmed ID: 33853954 SARS-CoV-2 Spike E484K Mutation Reduces Antibody Neutralisation The Lancet. Microbe. Jul, 2021 | Pubmed ID: 33846703 A Metal Ion Orients MRNA to Ensure Accurate 2'- Ribosyl Methylation of the First Nucleotide of the SARS-CoV-2 Genome BioRxiv : the Preprint Server for Biology. Mar, 2021 | Pubmed ID: 33758845 Antiviral Activity of Oleandrin and a Defined Extract of Nerium Oleander Against SARS-CoV-2 Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Jun, 2021 | Pubmed ID: 33721754 A Safe and Highly Efficacious Measles Virus-based Vaccine Expressing SARS-CoV-2 Stabilized Prefusion Spike Proceedings of the National Academy of Sciences of the United States of America. 03, 2021 | Pubmed ID: 33688034 Therapeutic Activity of an Inhaled Potent SARS-CoV-2 Neutralizing Human Monoclonal Antibody in Hamsters Cell Reports. Medicine. Mar, 2021 | Pubmed ID: 33649747 The E484K Mutation in the SARS-CoV-2 Spike Protein Reduces but Does Not Abolish Neutralizing Activity of Human Convalescent and Post-vaccination Sera MedRxiv : the Preprint Server for Health Sciences. Jan, 2021 | Pubmed ID: 33532796 Selection, Identification, and Characterization of SARS-CoV-2 Monoclonal Antibody Resistant Mutants Journal of Virological Methods. 04, 2021 | Pubmed ID: 33513380 Author Correction: Responses to Acute Infection with SARS-CoV-2 in the Lungs of Rhesus Macaques, Baboons and Marmosets Nature Microbiology. Mar, 2021 | Pubmed ID: 33462437 Generation and Characterization of Recombinant SARS-CoV-2 Expressing Reporter Genes Journal of Virology. Jan, 2021 | Pubmed ID: 33431557 Responses to Acute Infection with SARS-CoV-2 in the Lungs of Rhesus Macaques, Baboons and Marmosets Nature Microbiology. 01, 2021 | Pubmed ID: 33340034 Rapid in Vitro Assays for Screening Neutralizing Antibodies and Antivirals Against SARS-CoV-2 Journal of Virological Methods. 01, 2021 | Pubmed ID: 33068703 Editorial Overview: Virus Reverse Genetics Approaches for the Development of Preventive and Therapeutic Vaccines Current Opinion in Virology. 10, 2020 | Pubmed ID: 33349418 Development of a High-Throughput Homogeneous AlphaLISA Drug Screening Assay for the Detection of SARS-CoV-2 Nucleocapsid ACS Pharmacology & Translational Science. Dec, 2020 | Pubmed ID: 33330840 Lethality of SARS-CoV-2 Infection in K18 Human Angiotensin-converting Enzyme 2 Transgenic Mice Nature Communications. 11, 2020 | Pubmed ID: 33257679 SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination Advanced Materials (Deerfield Beach, Fla.). Dec, 2020 | Pubmed ID: 33111375 Generation of Recombinant SARS-CoV-2 Using a Bacterial Artificial Chromosome Current Protocols in Microbiology. 12, 2020 | Pubmed ID: 33048448 Rescue of SARS-CoV-2 from a Single Bacterial Artificial Chromosome MBio. 09, 2020 | Pubmed ID: 32978313 Identification of Inhibitors of ZIKV Replication Viruses. 09, 2020 | Pubmed ID: 32961956 Development of a High-throughput Homogeneous AlphaLISA Drug Screening Assay for the Detection of SARS-CoV-2 Nucleocapsid BioRxiv : the Preprint Server for Biology. Aug, 2020 | Pubmed ID: 32839774 Reverse Genetics Approaches for the Development of Mammarenavirus Live-attenuated Vaccines Current Opinion in Virology. 10, 2020 | Pubmed ID: 32721864 Structural Basis of RNA Cap Modification by SARS-CoV-2 Nature Communications. 07, 2020 | Pubmed ID: 32709886 Discovery of SARS-CoV-2 Antiviral Drugs Through Large-scale Compound Repurposing Nature. 10, 2020 | Pubmed ID: 32707573 Development of Reverse Genetics for the Prototype New World Mammarenavirus Tacaribe Virus Journal of Virology. 09, 2020 | Pubmed ID: 32669332 AGL2017-82570-RReverse Genetics Approaches for the Development of New Vaccines Against Influenza A Virus Infections Current Opinion in Virology. 10, 2020 | Pubmed ID: 32599532 An In Vitro Microneutralization Assay for SARS-CoV-2 Serology and Drug Screening Current Protocols in Microbiology. 09, 2020 | Pubmed ID: 32585083 Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus BioRxiv : the Preprint Server for Biology. Apr, 2020 | Pubmed ID: 32511383 Differences in Tissue and Species Tropism of Reptarenavirus Species Studied by Vesicular Stomatitis Virus Pseudotypes Viruses. 04, 2020 | Pubmed ID: 32252443 BH3 Helix-derived Biophotonic Nanoswitches Regulate Cytochrome C Release in Permeabilised Cells Molecular BioSystems. Nov, 2013 | Pubmed ID: 23942570 Echocardiographic Methods, Quality Review, and Measurement Accuracy in a Randomized Multicenter Clinical Trial of Marfan Syndrome Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. Apr, 2013 | Pubmed ID: 23582510 Development and Implementation of an EPID-based Method for Localizing Isocenter Journal of Applied Clinical Medical Physics / American College of Medical Physics. 2012 | Pubmed ID: 23149787 Measurement of Low-energy Backscatter Factors Using GAFCHROMIC Film and OSLDs Journal of Applied Clinical Medical Physics / American College of Medical Physics. 2012 | Pubmed ID: 23149776 (1)H, (13)C and (15)N Chemical Shift Assignments of Unliganded Bcl-x(L) and Its Complex with a Photoresponsive Bak-derived Peptide Biomolecular NMR Assignments. Jun, 2012 | Pubmed ID: 22744789 NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-xL Journal of the American Chemical Society. May, 2012 | Pubmed ID: 22515821 Gestaltung Der Photocontrolled RNS-bindene Peptidmimetika Chembiochem : a European Journal of Chemical Biology. Feb, 2012 | Pubmed ID: 22302640 Top-Prioritäten Für Alkohol-Regler in Den Vereinigten Staaten: Schutz Der öffentlichen Gesundheit Oder Der Alkoholindustrie? Addiction (Abingdon, England). Feb, 2012 | Pubmed ID: 22248136 Postoperativ Sezieren Ventrikulärer Septumdefekt Hämatom: Erkennung Und Behandlung ISRN Pediatrics. 2011 | Pubmed ID: 22389781 Dreidimensionale Intertrabekuläre Auswertung Der Fontan-Conduit Für Thrombus Echocardiography (Mount Kisco, N.Y.). Nov, 2011 | Pubmed ID: 22098492 Chemische Synthese Von Apoptotic Zelle-durchlässigen Peptide Aus In-vivo Produzierten Proteine Bioconjugate Chemistry. Sep, 2011 | Pubmed ID: 21823633 Alkohol Vermarktung Im 21. Jahrhundert: Neue Methoden, Alte Probleme Substance Use & Misuse. 2011 | Pubmed ID: 21599504 Biomimetische Antifouling Oberflächen Entwerfen Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. Oct, 2010 | Pubmed ID: 20855318 Ausnutzung Der Biokatalyse in Peptid Selbstmontage Biopolymers. 2010 | Pubmed ID: 20091879 Endokarditis Nach Pectus Excavatum Reparatur: Ein Fallbericht Circulation. Cardiovascular Imaging. Jan, 2009 | Pubmed ID: 19808566 Erstellen Von Funktionalen Vesikel-Assemblys Aus Bläschen Und Nanopartikel Pharmaceutical Research. Jul, 2009 | Pubmed ID: 19387801 Magnetisch Kontrollierte Freisetzung Aus Hydrogel-unterstützte Vesikel Assemblys Chemical Communications (Cambridge, England). May, 2009 | Pubmed ID: 19377661 Optimale Kopfposition Beim Transösophagealen Intertrabekuläre Sonde Einfügen Für Pädiatrische Patienten Mit Einem Gewicht Von Bis Zu 10 Kg Pediatric Cardiology. May, 2009 | Pubmed ID: 19219486 Bewertung Der Rechtsventrikulären Größe Und Funktion: Echo Gegenüber Magnetresonanz-Bildgebung Congenital Heart Disease. Jan-Feb, 2007 | Pubmed ID: 18377513 Magnetplatte Und Musterung Der Vesikel/Nanopartikel-Aggregate Journal of the American Chemical Society. Oct, 2007 | Pubmed ID: 17867688 Vesikel-Aggregation Von Multivalenter Liganden: Vernetzung Fähigkeit Zur Oberfläche Affinität Organic & Biomolecular Chemistry. Aug, 2007 | Pubmed ID: 17637972 Mittelfristige Ergebnisse Der Reparatur Für Aorta, Neoaortic Und Vermehrtes Ventil Insuffizienz Bei Kindern The Journal of Thoracic and Cardiovascular Surgery. May, 2007 | Pubmed ID: 17467448 (2S, 12Z)-2-Acetoxy-12-Heptadecene: Große Geschlecht Pheromon-Komponente Von Pistazien Twig Borer, Kermania Pistaciella Journal of Chemical Ecology. Dec, 2006 | Pubmed ID: 17123172 Die Wirkung Des Rezeptors Clustering Auf Vesikel-Vesikel Adhäsion Journal of the American Chemical Society. Nov, 2006 | Pubmed ID: 17090021 Differenzielle Querschnitt Und Photon-Beam/Ausleuchtzone Asymmetrie Für Die Gamma-n--> K + Sigma-Reaktion Am E-Gamma = 1.5-2.4 GeV Physical Review Letters. Aug, 2006 | Pubmed ID: 17026294 Sicherheit Und Wirksamkeit Von Sedierung Mit Propofol Für Transösophageale Echokardiographie Bei Kindern in Eine Ambulante Festlegen Cardiology in the Young. Apr, 2006 | Pubmed ID: 16553977 Extrakorporale Membranoxygenierung Als Brücke Zur Chirurgischen Behandlung Der Dreschflegel Tricuspid Ventil in Einem Neugeborenen Cardiology in the Young. Dec, 2005 | Pubmed ID: 16297265 Live-Bildgebung und Quantifizierung von Virusinfektionen in transgenen K18-hACE2-Mäusen mit Reporter-exprimierendem rekombinantem SARS-CoV-2 Desarey Morales Vasquez1, Kevin Chiem1, Jesus Silvas1, Jun-Gyu Park1, Chengjin Ye1, Luis Martínez-Sobrido1 1Texas Biomedical Research Institute JoVE 63127 Immunology and Infection Rettung des rekombinanten Zika-Virus aus einem bakteriellen künstlichen Chromosom cDNA-Klon Ginés Ávila-Pérez1, Jun-Gyu Park1, Aitor Nogales1, Fernando Almazán2, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester Medical Center, 2Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid JoVE 59537 Immunology and Infection Influenza-A-Virus-Studien in einem Mausmodell der Infektion Laura Rodriguez1, Aitor Nogales1, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry JoVE 55898 Immunology and Infection Rettung von rekombinanten Newcastle Disease Virus aus cDNA Juan Ayllon1,2, Adolfo García-Sastre1,2,3, Luis Martínez-Sobrido4 1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, 3Department of Medicine, Icahn School of Medicine at Mount Sinai, 4Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester JoVE 50830 Immunology and Infection Erzeugung von rekombinanten Arenavirus für die Impfstoffentwicklung in FDA-zugelassenen Vero-Zellen Benson Y.H. Cheng*1, Emilio Ortiz-Riaño*1, Juan Carlos de la Torre2, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 2Departments of Immunology and Microbial Sciences, The Scripps Research Institute JoVE 50662 Immunology and Infection Erzeugung von rekombinanten Influenza Virus von Plasmid-DNA Luis Martínez-Sobrido1, Adolfo García-Sastre2 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 2Departments of Microbiology and Medicine, and Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine JoVE 2057 Immunology and Infection
Live-Bildgebung und Quantifizierung von Virusinfektionen in transgenen K18-hACE2-Mäusen mit Reporter-exprimierendem rekombinantem SARS-CoV-2 Desarey Morales Vasquez1, Kevin Chiem1, Jesus Silvas1, Jun-Gyu Park1, Chengjin Ye1, Luis Martínez-Sobrido1 1Texas Biomedical Research Institute JoVE 63127 Immunology and Infection
Rettung des rekombinanten Zika-Virus aus einem bakteriellen künstlichen Chromosom cDNA-Klon Ginés Ávila-Pérez1, Jun-Gyu Park1, Aitor Nogales1, Fernando Almazán2, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester Medical Center, 2Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid JoVE 59537 Immunology and Infection
Influenza-A-Virus-Studien in einem Mausmodell der Infektion Laura Rodriguez1, Aitor Nogales1, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry JoVE 55898 Immunology and Infection
Rettung von rekombinanten Newcastle Disease Virus aus cDNA Juan Ayllon1,2, Adolfo García-Sastre1,2,3, Luis Martínez-Sobrido4 1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, 3Department of Medicine, Icahn School of Medicine at Mount Sinai, 4Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester JoVE 50830 Immunology and Infection
Erzeugung von rekombinanten Arenavirus für die Impfstoffentwicklung in FDA-zugelassenen Vero-Zellen Benson Y.H. Cheng*1, Emilio Ortiz-Riaño*1, Juan Carlos de la Torre2, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 2Departments of Immunology and Microbial Sciences, The Scripps Research Institute JoVE 50662 Immunology and Infection
Erzeugung von rekombinanten Influenza Virus von Plasmid-DNA Luis Martínez-Sobrido1, Adolfo García-Sastre2 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 2Departments of Microbiology and Medicine, and Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine JoVE 2057 Immunology and Infection