Luke Alphey

Publications

• PNUTS/PP1 Regulates RNAPII-mediated Gene Expression and is Necessary for Developmental Growth
  PLoS Genetics. Oct, 2013  |   Pubmed ID: 24204300
• Genetic Control of Mosquitoes
  Annual Review of Entomology. Oct, 2013  |   Pubmed ID: 24160434
• DsRed2 Transient Expression in Culex Quinquefasciatus Mosquitoes
  Memórias Do Instituto Oswaldo Cruz. Jun, 2013  |   Pubmed ID: 23828005
• Genetic Control of Aedes Mosquitoes
  Pathogens and Global Health. Jun, 2013  |   Pubmed ID: 23816508
• Engineered Female-specific Lethality for Control of Pest Lepidoptera
  ACS Synthetic Biology. Mar, 2013  |   Pubmed ID: 23802263
• Fitness of Transgenic Mosquito Aedes Aegypti Males Carrying a Dominant Lethal Genetic System
  PloS One. 2013  |   Pubmed ID: 23690948
• Development of a Population Suppression Strain of the Human Malaria Vector Mosquito, Anopheles Stephensi
  Malaria Journal. 2013  |   Pubmed ID: 23622561
• Transgene-based, Female-specific Lethality System for Genetic Sexing of the Silkworm, Bombyx Mori
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013  |   Pubmed ID: 23569267
• Oral Ingestion of Transgenic RIDL Ae. Aegypti Larvae Has No Negative Effect on Two Predator Toxorhynchites Species
  PloS One. 2013  |   Pubmed ID: 23527029
• The Orthologue of the Fruitfly Sex Behaviour Gene Fruitless in the Mosquito Aedes Aegypti: Evolution of Genomic Organisation and Alternative Splicing
  PloS One. 2013  |   Pubmed ID: 23418412
• Polymerase Chain Displacement Reaction
  BioTechniques. Feb, 2013  |   Pubmed ID: 23384180
• Field Cage Studies and Progressive Evaluation of Genetically-engineered Mosquitoes
  PLoS Neglected Tropical Diseases. 2013  |   Pubmed ID: 23350003
• Mating Compatibility and Competitiveness of Transgenic and Wild Type Aedes Aegypti (L.) Under Contained Semi-field Conditions
  Transgenic Research. Feb, 2013  |   Pubmed ID: 22700207
• Engineered Repressible Lethality for Controlling the Pink Bollworm, a Lepidopteran Pest of Cotton
  PloS One. 2012  |   Pubmed ID: 23226548
• Open Field Release of Genetically Engineered Sterile Male Aedes Aegypti in Malaysia
  PloS One. 2012  |   Pubmed ID: 22970102
• Successful Suppression of a Field Mosquito Population by Sustained Release of Engineered Male Mosquitoes
  Nature Biotechnology. Sep, 2012  |   Pubmed ID: 22965050
• Flight Performance and Teneral Energy Reserves of Two Genetically-modified and One Wild-type Strain of the Yellow Fever Mosquito Aedes Aegypti
  Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). Dec, 2012  |   Pubmed ID: 22835152
• Female-specific Flightless (fsRIDL) Phenotype for Control of Aedes Albopictus
  PLoS Neglected Tropical Diseases. 2012  |   Pubmed ID: 22802980
• Control of the Olive Fruit Fly Using Genetics-enhanced Sterile Insect Technique
  BMC Biology. 2012  |   Pubmed ID: 22713628
• Field Longevity of a Fluorescent Protein Marker in an Engineered Strain of the Pink Bollworm, Pectinophora Gossypiella (Saunders)
  PloS One. 2012  |   Pubmed ID: 22693645
• DengueTools: Innovative Tools and Strategies for the Surveillance and Control of Dengue
  Global Health Action. 2012  |   Pubmed ID: 22451836
• Appropriate Regulation of GM Insects
  PLoS Neglected Tropical Diseases. Jan, 2012  |   Pubmed ID: 22303495
• Multiplex Detection and SNP Genotyping in a Single Fluorescence Channel
  PloS One. 2012  |   Pubmed ID: 22272339
• Field Performance of Engineered Male Mosquitoes
  Nature Biotechnology. Nov, 2011  |   Pubmed ID: 22037376
• Cost of Mating and Insemination Capacity of a Genetically Modified Mosquito Aedes Aegypti OX513A Compared to Its Wild Type Counterpart
  PloS One. 2011  |   Pubmed ID: 22022518
• A Model Framework to Estimate Impact and Cost of Genetics-based Sterile Insect Methods for Dengue Vector Control
  PloS One. 2011  |   Pubmed ID: 21998654
• Field Performance of a Genetically Engineered Strain of Pink Bollworm
  PloS One. 2011  |   Pubmed ID: 21931649
• Comparison of Life History Characteristics of the Genetically Modified OX513A Line and a Wild Type Strain of Aedes Aegypti
  PloS One. 2011  |   Pubmed ID: 21698096
• Why RIDL is Not SIT
  Trends in Parasitology. Aug, 2011  |   Pubmed ID: 21659002
• Genetic Elimination of Dengue Vector Mosquitoes
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011  |   Pubmed ID: 21383140
• Modeling Resistance to Genetic Control of Insects
  Journal of Theoretical Biology. Feb, 2011  |   Pubmed ID: 21075122
• Irritant and Repellent Behavioral Responses of Aedes Aegypti Male Populations Developed for RIDL Disease Control Strategies
  Journal of Medical Entomology. Nov, 2010  |   Pubmed ID: 21175058
• Use of a Regulatory Mechanism of Sex Determination in Pest Insect Control
  Journal of Genetics. Sep, 2010  |   Pubmed ID: 20876996
• Piggybac- and PhiC31-mediated Genetic Transformation of the Asian Tiger Mosquito, Aedes Albopictus (Skuse)
  PLoS Neglected Tropical Diseases. 2010  |   Pubmed ID: 20808959
• Transcriptomics and Disease Vector Control
  BMC Biology. 2010  |   Pubmed ID: 20525113
• Female-specific Flightless Phenotype for Mosquito Control
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010  |   Pubmed ID: 20176967
• Sterile-insect Methods for Control of Mosquito-borne Diseases: an Analysis
  Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). Apr, 2010  |   Pubmed ID: 19725763
• Sex Separation Strategies: Past Experience and New Approaches
  Malaria Journal. 2009  |   Pubmed ID: 19917075
• Combining Pest Control and Resistance Management: Synergy of Engineered Insects with Bt Crops
  Journal of Economic Entomology. Apr, 2009  |   Pubmed ID: 19449654
• Natural and Engineered Mosquito Immunity
  Journal of Biology. 2009  |   Pubmed ID: 19439051
• Interview with Luke Alphey, Ph.D. [Interview by Vicki Glaser]
  Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). Apr, 2009  |   Pubmed ID: 19371156
• Insect Population Suppression Using Engineered Insects
  Advances in Experimental Medicine and Biology. 2008  |   Pubmed ID: 18510017
• Drosophila Uri, a PP1alpha Binding Protein, is Essential for Viability, Maintenance of DNA Integrity and Normal Transcriptional Activity
  BMC Molecular Biology. 2008  |   Pubmed ID: 18412953
• Managing Insecticide Resistance by Mass Release of Engineered Insects
  Journal of Economic Entomology. Oct, 2007  |   Pubmed ID: 17972643
• Genetic Sexing Through the Use of Y-linked Transgenes
  Insect Biochemistry and Molecular Biology. Nov, 2007  |   Pubmed ID: 17916503
• Analyzing the Control of Mosquito-borne Diseases by a Dominant Lethal Genetic System
  Proceedings of the National Academy of Sciences of the United States of America. May, 2007  |   Pubmed ID: 17519336
• Essential, Overlapping and Redundant Roles of the Drosophila Protein Phosphatase 1 Alpha and 1 Beta Genes
  Genetics. May, 2007  |   Pubmed ID: 17513890
• Late-acting Dominant Lethal Genetic Systems and Mosquito Control
  BMC Biology. 2007  |   Pubmed ID: 17374148
• Female-specific Insect Lethality Engineered Using Alternative Splicing
  Nature Biotechnology. Mar, 2007  |   Pubmed ID: 17322873
• The Nonmuscle Myosin Phosphatase PP1beta (flapwing) Negatively Regulates Jun N-terminal Kinase in Wing Imaginal Discs of Drosophila
  Genetics. Apr, 2007  |   Pubmed ID: 17277363
• Yeast Two-hybrid Screens to Identify Drosophila PP1-binding Proteins
  Methods in Molecular Biology (Clifton, N.J.). 2007  |   Pubmed ID: 17200561
• Towards a Comprehensive Analysis of the Protein Phosphatase 1 Interactome in Drosophila
  Journal of Molecular Biology. Nov, 2006  |   Pubmed ID: 17007873
• Transposon-free Insertions for Insect Genetic Engineering
  Nature Biotechnology. Jul, 2006  |   Pubmed ID: 16823373
• CG15031/PPYR1 is an Intrinsically Unstructured Protein That Interacts with Protein Phosphatase Y
  Archives of Biochemistry and Biophysics. Jul, 2006  |   Pubmed ID: 16631104
• Mosquito Transgenesis: What is the Fitness Cost?
  Trends in Parasitology. May, 2006  |   Pubmed ID: 16564223
• Germ Line Specific Expression of a Protein Phosphatase Y Interacting Protein (PPYR1) in Drosophila
  Gene Expression Patterns : GEP. Oct, 2006  |   Pubmed ID: 16530491
• Bifocal and PP1 Interaction Regulates Targeting of the R-cell Growth Cone in Drosophila
  Developmental Biology. Dec, 2005  |   Pubmed ID: 16280124
• A Dominant Lethal Genetic System for Autocidal Control of the Mediterranean Fruitfly
  Nature Biotechnology. Apr, 2005  |   Pubmed ID: 15750586
• PP1beta9C Interacts with Trithorax in Drosophila Wing Development
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2004  |   Pubmed ID: 15366010
• The Essential Role of PP1beta in Drosophila is to Regulate Nonmuscle Myosin
  Molecular Biology of the Cell. Oct, 2004  |   Pubmed ID: 15269282
• Cloning and Expression of Mars, a Novel Member of the Guanylate Kinase Associated Protein Family in Drosophila
  Gene Expression Patterns : GEP. Sep, 2004  |   Pubmed ID: 15261830
• Genetic Control of Vector Populations: an Imminent Prospect
  Tropical Medicine & International Health : TM & IH. Apr, 2004  |   Pubmed ID: 15078260
• Giant Nuclei is Essential in the Cell Cycle Transition from Meiosis to Mitosis
  Development (Cambridge, England). Jul, 2003  |   Pubmed ID: 12756181
• Ectopic Expression of Inhibitors of Protein Phosphatase Type 1 (PP1) Can Be Used to Analyze Roles of PP1 in Drosophila Development
  Genetics. May, 2003  |   Pubmed ID: 12750335
• Trithorax Interacts with Type 1 Serine/threonine Protein Phosphatase in Drosophila
  EMBO Reports. Jan, 2003  |   Pubmed ID: 12524522
• Malaria Control with Genetically Manipulated Insect Vectors
  Science (New York, N.Y.). Oct, 2002  |   Pubmed ID: 12364786
• Functional Interaction Between Nuclear Inhibitor of Protein Phosphatase Type 1 (NIPP1) and Protein Phosphatase Type 1 (PP1) in Drosophila: Consequences of Over-expression of NIPP1 in Flies and Suppression by Co-expression of PP1
  The Biochemical Journal. Dec, 2002  |   Pubmed ID: 12358598
• Re-engineering the Sterile Insect Technique
  Insect Biochemistry and Molecular Biology. Oct, 2002  |   Pubmed ID: 12225915
• PP1 Binds Sara and Negatively Regulates Dpp Signaling in Drosophila Melanogaster
  Nature Genetics. Aug, 2002  |   Pubmed ID: 12134149
• Dominant Lethality and Insect Population Control
  Molecular and Biochemical Parasitology. May, 2002  |   Pubmed ID: 12034450