Lynn E. Macdonald Regeneron Tech Centers Regeneron Pharmaceuticals, Inc. Biography Publications Institution JoVE Articles Lynn E. Macdonald has not added a biography. If you are Lynn E. Macdonald and would like to personalize this page please email our Author Liaison for assistance. Publications Kappa-on-Heavy (KoH) Bodies Are a Distinct Class of Fully-human Antibody-like Therapeutic Agents with Antigen-binding Properties Proceedings of the National Academy of Sciences of the United States of America. 01, 2020 | Pubmed ID: 31879340 The Anti-IgE MAb Omalizumab Induces Adverse Reactions by Engaging Fcγ Receptors The Journal of Clinical Investigation. 03, 2020 | Pubmed ID: 31770111 Publisher Correction: An Engineered Human Fc Domain That Behaves Like a PH-toggle Switch for Ultra-long Circulation Persistence Nature Communications. Nov, 2019 | Pubmed ID: 31767870 An Engineered Human Fc Domain That Behaves Like a PH-toggle Switch for Ultra-long Circulation Persistence Nature Communications. 11, 2019 | Pubmed ID: 31695028 A Short Isoform of Coagulation Factor XII MRNA Is Expressed by Neurons in the Human Brain Neuroscience. 08, 2019 | Pubmed ID: 31181367 Deletion of Adam6 in Mus Musculus Leads to Male Subfertility and Deficits in Sperm Ascent into the Oviduct Biology of Reproduction. 03, 2019 | Pubmed ID: 30289441 A Function-blocking PAR4 Antibody is Markedly Antithrombotic in the Face of a Hyperreactive PAR4 Variant Blood Advances. 06, 2018 | Pubmed ID: 29884748 Platelets Expressing IgG Receptor FcγRIIA/CD32A Determine the Severity of Experimental Anaphylaxis Science Immunology. 04, 2018 | Pubmed ID: 29654057 Humanized Mouse Model Supports Development, Function, and Tissue Residency of Human Natural Killer Cells Proceedings of the National Academy of Sciences of the United States of America. 11, 2017 | Pubmed ID: 29078283 Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice Journal of Immunology (Baltimore, Md. : 1950). 02, 2017 | Pubmed ID: 28011932 In vivo Effector Functions of High-affinity Mouse IgG Receptor FcγRI in Disease and Therapy Models Journal of Autoimmunity. Jun, 2017 | Pubmed ID: 27745779 Precise and in Situ Genetic Humanization of 6 Mb of Mouse Immunoglobulin Genes Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706858 Mice with Megabase Humanization of Their Immunoglobulin Genes Generate Antibodies As Efficiently As Normal Mice Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706856 Angiogenic Sprouting into Neural Tissue Requires Gpr124, an Orphan G Protein-coupled Receptor Proceedings of the National Academy of Sciences of the United States of America. Feb, 2011 | Pubmed ID: 21282641 Resistance to Diet-induced Obesity in Mice Globally Overexpressing OGH/GPB5 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15699348 High-throughput Engineering of the Mouse Genome Coupled with High-resolution Expression Analysis Nature Biotechnology. Jun, 2003 | Pubmed ID: 12730667 Flow Cytometric Characterization of Murine B Cell Development Faith M. Harris*1, Karoline A. Meagher*1, Maggie Zhong1, Benjamin J. Daniel2, Mark Eckersdorff1, Jesse A. Green1, Vera Voronina1, Chunguang Guo1, Andre Limnander3, Lynn E. Macdonald1 1Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., 2Regeneron Therapeutic Proteins, Regeneron Pharmaceuticals, Inc., 3Immunology and Inflammation, Regeneron Pharmaceuticals, Inc. JoVE 61565 Immunology and Infection
Flow Cytometric Characterization of Murine B Cell Development Faith M. Harris*1, Karoline A. Meagher*1, Maggie Zhong1, Benjamin J. Daniel2, Mark Eckersdorff1, Jesse A. Green1, Vera Voronina1, Chunguang Guo1, Andre Limnander3, Lynn E. Macdonald1 1Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., 2Regeneron Therapeutic Proteins, Regeneron Pharmaceuticals, Inc., 3Immunology and Inflammation, Regeneron Pharmaceuticals, Inc. JoVE 61565 Immunology and Infection
