M. Luisa Iruela-Arispe Department of Molecular, Cell and Developmental Biology UCLA Biography Publications Institution JoVE Articles M. Luisa Iruela-Arispe has not added a biography. If you are M. Luisa Iruela-Arispe and would like to personalize this page please email our Author Liaison for assistance. Publications Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer Scientific Reports. Jun, 2018 | Pubmed ID: 29899427 Vav3-induced Cytoskeletal Dynamics Contribute to Heterotypic Properties of Endothelial Barriers The Journal of Cell Biology. Jun, 2018 | Pubmed ID: 29858212 Metastasis of Circulating Tumor Cells: Speed Matters Developmental Cell. 04, 2018 | Pubmed ID: 29634934 A Multi-step Transcriptional Cascade Underlies Vascular Regeneration in Vivo Scientific Reports. Apr, 2018 | Pubmed ID: 29615716 NOTCH Regulation of the Endothelial Cell Phenotype Current Opinion in Hematology. May, 2018 | Pubmed ID: 29547401 Analysis of Cardiomyocyte Clonal Expansion During Mouse Heart Development and Injury Nature Communications. 02, 2018 | Pubmed ID: 29467410 A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis Cell Reports. Jan, 2018 | Pubmed ID: 29386109 NOTCH1 is a Mechanosensor in Adult Arteries Nature Communications. Nov, 2017 | Pubmed ID: 29158473 Transgenic Tomatoes Expressing the 6F Peptide and Ezetimibe Prevent Diet-induced Increases of IFN-β and Cholesterol 25-hydroxylase in Jejunum Journal of Lipid Research. Aug, 2017 | Pubmed ID: 28592401 Cell-type Deconvolution with Immune Pathways Identifies Gene Networks of Host Defense and Immunopathology in Leprosy JCI Insight. Sep, 2016 | Pubmed ID: 27699251 Perivascular Macrophages Limit Permeability Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2016 | Pubmed ID: 27634833 Notch, Lipids, and Endothelial Cells Current Opinion in Lipidology. Oct, 2016 | Pubmed ID: 27454451 Cross-talk Between Signaling and Metabolism in the Vasculature Vascular Pharmacology. Aug, 2016 | Pubmed ID: 27291139 Endothelial NOTCH1 is Suppressed by Circulating Lipids and Antagonizes Inflammation During Atherosclerosis The Journal of Experimental Medicine. Nov, 2015 | Pubmed ID: 26552708 Endothelial RhoGEFs: A Systematic Analysis of Their Expression Profiles in VEGF-stimulated and Tumor Endothelial Cells Vascular Pharmacology. Nov, 2015 | Pubmed ID: 26471833 Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer Cancer Research. Nov, 2015 | Pubmed ID: 26471360 Healing Arterial Ulcers: Endothelial Lining Regeneration Upon Vascular Denudation Injury Vascular Pharmacology. Sep, 2015 | Pubmed ID: 26093336 Autocrine VEGF Maintains Endothelial Survival Through Regulation of Metabolism and Autophagy Journal of Cell Science. Jun, 2015 | Pubmed ID: 25956888 State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association Circulation Research. May, 2015 | Pubmed ID: 25931450 ADAMTS Proteases in Vascular Biology Matrix Biology : Journal of the International Society for Matrix Biology. May-Jul, 2015 | Pubmed ID: 25698314 Blockade of Specific NOTCH Ligands: a New Promising Approach in Cancer Therapy Cancer Discovery. Feb, 2015 | Pubmed ID: 25656896 Canonical and Noncanonical Vascular Endothelial Growth Factor Pathways: New Developments in Biology and Signal Transduction Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2015 | Pubmed ID: 25278287 Repression of Sox9 by Jag1 is Continuously Required to Suppress the Default Chondrogenic Fate of Vascular Smooth Muscle Cells Developmental Cell. Dec, 2014 | Pubmed ID: 25535917 Stealing VEGF from Thy Neighbor Cell. Oct, 2014 | Pubmed ID: 25417099 Podosome Rosettes Precede Vascular Sprouts in Tumour Angiogenesis Nature Cell Biology. Oct, 2014 | Pubmed ID: 25271481 The Chicken Chorioallantoic Membrane Model in Biology, Medicine and Bioengineering Angiogenesis. Oct, 2014 | Pubmed ID: 25138280 Local Acting Sticky-trap Inhibits Vascular Endothelial Growth Factor Dependent Pathological Angiogenesis in the Eye EMBO Molecular Medicine. May, 2014 | Pubmed ID: 24705878 Progesterone Receptor in the Vascular Endothelium Triggers Physiological Uterine Permeability Preimplantation Cell. Jan, 2014 | Pubmed ID: 24485460 Hybrid Photopatterned Enzymatic Reaction (HyPER) for in Situ Cell Manipulation Chembiochem : a European Journal of Chemical Biology. Jan, 2014 | Pubmed ID: 24399784 A Ligand-independent VEGFR2 Signaling Pathway Limits Angiogenic Responses in Diabetes Science Signaling. Jan, 2014 | Pubmed ID: 24399295 Sox17 is Indispensable for Acquisition and Maintenance of Arterial Identity Nature Communications. 2013 | Pubmed ID: 24153254 The Mouse Retina in 3D: Quantification of Vascular Growth and Remodeling Integrative Biology : Quantitative Biosciences from Nano to Macro. Dec, 2013 | Pubmed ID: 24136100 β1-integrin is Essential for Vasoregulation and Smooth Muscle Survival in Vivo Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2013 | Pubmed ID: 23887637 Tubulogenesis Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23821032 Selective Suppression of Endothelial Cytokine Production by Progesterone Receptor Vascular Pharmacology. Jul-Aug, 2013 | Pubmed ID: 23747964 Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy Cancer Research. Aug, 2013 | Pubmed ID: 23744837 Notch1 Regulates Angio-supportive Bone Marrow-derived Cells in Mice: Relevance to Chemoresistance Blood. Jul, 2013 | Pubmed ID: 23690447 Reciprocal Interactions Between Endothelial Cells and Macrophages in Angiogenic Vascular Niches Experimental Cell Research. Jul, 2013 | Pubmed ID: 23542777 Dll4-Notch Signaling Determines the Formation of Native Arterial Collateral Networks and Arterial Function in Mouse Ischemia Models Development (Cambridge, England). Apr, 2013 | Pubmed ID: 23533173 Testosterone Levels Influence Mouse Fetal Leydig Cell Progenitors Through Notch Signaling Biology of Reproduction. Apr, 2013 | Pubmed ID: 23467742 Cellular and Molecular Regulation of Vascular Permeability Thrombosis and Haemostasis. Mar, 2013 | Pubmed ID: 23389236 Real-time Maps of Fluid Flow Fields in Porous Biomaterials Biomaterials. Mar, 2013 | Pubmed ID: 23245922 Endothelial Deletion of Murine Jag1 Leads to Valve Calcification and Congenital Heart Defects Associated with Alagille Syndrome Development (Cambridge, England). Dec, 2012 | Pubmed ID: 23095891 Selective Decline of Synaptic Protein Levels in the Frontal Cortex of Female Mice Deficient in the Extracellular Metalloproteinase ADAMTS1 PloS One. 2012 | Pubmed ID: 23071766 Endothelial Cells Provide an Instructive Niche for the Differentiation and Functional Polarization of M2-like Macrophages Blood. Oct, 2012 | Pubmed ID: 22919031 ApoB-containing Lipoproteins Regulate Angiogenesis by Modulating Expression of VEGF Receptor 1 Nature Medicine. Jun, 2012 | Pubmed ID: 22581286 Recent Advances in Vascular Development Current Opinion in Hematology. May, 2012 | Pubmed ID: 22406825 Trophoblasts Regulate the Placental Hematopoietic Niche Through PDGF-B Signaling Developmental Cell. Mar, 2012 | Pubmed ID: 22387002 CCN2/connective Tissue Growth Factor is Essential for Pericyte Adhesion and Endothelial Basement Membrane Formation During Angiogenesis PloS One. 2012 | Pubmed ID: 22363445 Un Requisito Esencial Para Integrinas β1 En El Conjunto De Proteínas De Matriz Extracelular Dentro De La Pared Vascular Developmental Biology. May, 2012 | Pubmed ID: 22331032 Fibulin-1 is Required During Cardiac Ventricular Morphogenesis for Versican Cleavage, Suppression of ErbB2 and Erk1/2 Activation, and to Attenuate Trabecular Cardiomyocyte Proliferation Developmental Dynamics : an Official Publication of the American Association of Anatomists. Feb, 2012 | Pubmed ID: 22183742 Notch Promotes Vascular Maturation by Inducing Integrin-mediated Smooth Muscle Cell Adhesion to the Endothelial Basement Membrane Blood. Mar, 2012 | Pubmed ID: 22134168 Molecular Mechanisms of Tumor Angiogenesis Genes & Cancer. Dec, 2011 | Pubmed ID: 22866200 VEGF Internalization is Not Required for VEGFR-2 Phosphorylation in Bioengineered Surfaces with Covalently Linked VEGF Integrative Biology : Quantitative Biosciences from Nano to Macro. Sep, 2011 | Pubmed ID: 21826315 LUMENating Blood Vessels Developmental Cell. Apr, 2011 | Pubmed ID: 21497753 Jagged1 in the Portal Vein Mesenchyme Regulates Intrahepatic Bile Duct Development: Insights into Alagille Syndrome Development (Cambridge, England). Dec, 2010 | Pubmed ID: 21062863 Cuando Cre Mediada Por Recombinación En Ratones No Resulta En La Pérdida De La Proteína Genetics. Nov, 2010 | Pubmed ID: 20813881 Remodelado Vascular De La Arteria Vitelina Inicia Extravascular Aparición De Racimos Hematopoyéticos Blood. Nov, 2010 | Pubmed ID: 20699440 Endothelial Alpha3beta1-integrin Represses Pathological Angiogenesis and Sustains Endothelial-VEGF The American Journal of Pathology. Sep, 2010 | Pubmed ID: 20639457 The Wnt/beta-catenin Pathway Modulates Vascular Remodeling and Specification by Upregulating Dll4/Notch Signaling Developmental Cell. Jun, 2010 | Pubmed ID: 20627076 Signaling Circuitry in Vascular Morphogenesis Current Opinion in Hematology. May, 2010 | Pubmed ID: 20216211 Anchorage of VEGF to the Extracellular Matrix Conveys Differential Signaling Responses to Endothelial Cells The Journal of Cell Biology. Feb, 2010 | Pubmed ID: 20176926 Extracellular Matrix, Inflammation, and the Angiogenic Response Cardiovascular Research. May, 2010 | Pubmed ID: 20154066 Beta1 Integrin Establishes Endothelial Cell Polarity and Arteriolar Lumen Formation Via a Par3-dependent Mechanism Developmental Cell. Jan, 2010 | Pubmed ID: 20152176 Variable Inhibition of Thrombospondin 1 Against Liver and Lung Metastases Through Differential Activation of Metalloproteinase ADAMTS1 Cancer Research. Feb, 2010 | Pubmed ID: 20103648 Targeting Distinct Tumor-infiltrating Myeloid Cells by Inhibiting CSF-1 Receptor: Combating Tumor Evasion of Antiangiogenic Therapy Blood. Feb, 2010 | Pubmed ID: 20008303 Time to Cut the Cord: Placental HSCs Grow Up Cell Stem Cell. Oct, 2009 | Pubmed ID: 19796613 The Phosphorylation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) by Engineered Surfaces with Electrostatically or Covalently Immobilized VEGF Biomaterials. Sep, 2009 | Pubmed ID: 19540581 Conditional Cre/LoxP Strategies for the Study of Hematopoietic Stem Cell Formation Blood Cells, Molecules & Diseases. Jul-Aug, 2009 | Pubmed ID: 19250847 Cellular and Molecular Mechanisms of Vascular Lumen Formation Developmental Cell. Feb, 2009 | Pubmed ID: 19217424 Cleavage of Syndecan-4 by ADAMTS1 Provokes Defects in Adhesion The International Journal of Biochemistry & Cell Biology. Apr, 2009 | Pubmed ID: 18775505 Trazado De Destino Revela El Origen Endotelial De Células Madre Hematopoyéticas Cell Stem Cell. Dec, 2008 | Pubmed ID: 19041779 Regulation of Thrombospondin1 by Extracellular Proteases Current Drug Targets. Oct, 2008 | Pubmed ID: 18855620 Dicer-dependent Endothelial MicroRNAs Are Necessary for Postnatal Angiogenesis Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008 | Pubmed ID: 18779589 Multi-genetic Events Collaboratively Contribute to Pten-null Leukaemia Stem-cell Formation Nature. May, 2008 | Pubmed ID: 18463637 Endocardial Brg1 Represses ADAMTS1 to Maintain the Microenvironment for Myocardial Morphogenesis Developmental Cell. Feb, 2008 | Pubmed ID: 18267097 Autocrine VEGF Signaling is Required for Vascular Homeostasis Cell. Aug, 2007 | Pubmed ID: 17719546 Notch Signaling in Blood Vessels: Who is Talking to Whom About What? Circulation Research. Jun, 2007 | Pubmed ID: 17556669 A Través De Dll4 Señalización Notch1 Regula La Formación De Las Células De Consejos Durante La Angiogénesis Nature. Feb, 2007 | Pubmed ID: 17259973 Modulation of Protein Delivery from Modular Polymer Scaffolds Biomaterials. Apr, 2007 | Pubmed ID: 17184836 Notch Expression Patterns in the Retina: An Eye on Receptor-ligand Distribution During Angiogenesis Gene Expression Patterns : GEP. Feb, 2007 | Pubmed ID: 17161657 Anomalías Vasculares En Ratones Deficientes Para El Receptor De GPR4 Acoplado a Proteína G, Que Funciona Como Un Sensor De PH Molecular and Cellular Biology. Feb, 2007 | Pubmed ID: 17145776 ADAMTS1 Mediates the Release of Antiangiogenic Polypeptides from TSP1 and 2 The EMBO Journal. Nov, 2006 | Pubmed ID: 17082774 VE-cadherin-CreERT2 Transgenic Mouse: a Model for Inducible Recombination in the Endothelium Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2006 | Pubmed ID: 17072878 My O'Myeloid, a Tale of Two Lineages Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16924095 When It Comes to Blocking Lymphatics, It is All a Question of Time The American Journal of Pathology. Aug, 2006 | Pubmed ID: 16877337 Generation of a Mouse for Conditional Excision of Progesterone Receptor Genesis (New York, N.Y. : 2000). Aug, 2006 | Pubmed ID: 16868919 Proteolytic Cleavage of Versican During Cardiac Cushion Morphogenesis Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2006 | Pubmed ID: 16691565 The Ever-elusive Endothelial Progenitor Cell: Identities, Functions and Clinical Implications Pediatric Research. Apr, 2006 | Pubmed ID: 16549545 VE-Cadherin-Cre-recombinase Transgenic Mouse: a Tool for Lineage Analysis and Gene Deletion in Endothelial Cells Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2006 | Pubmed ID: 16450386 Fibulin-1 Acts As a Cofactor for the Matrix Metalloprotease ADAMTS-1 The Journal of Biological Chemistry. Oct, 2005 | Pubmed ID: 16061471 Enhanced Inhibition of Murine Tumor and Human Breast Tumor Xenografts Using Targeted Delivery of an Antibody-endostatin Fusion Protein Molecular Cancer Therapeutics. Jun, 2005 | Pubmed ID: 15956253 Processing of VEGF-A by Matrix Metalloproteinases Regulates Bioavailability and Vascular Patterning in Tumors The Journal of Cell Biology. May, 2005 | Pubmed ID: 15911882 ADAMTS1 Proteinase is Up-regulated in Wounded Skin and Regulates Migration of Fibroblasts and Endothelial Cells The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15843381 Notch Signaling in Vascular Morphogenesis Current Opinion in Hematology. Jul, 2004 | Pubmed ID: 15314528 Whence Thrombospondin? Cancer Biology & Therapy. Apr, 2004 | Pubmed ID: 15107618 Thrombospondin Modules and Angiogenesis The International Journal of Biochemistry & Cell Biology. Jun, 2004 | Pubmed ID: 15094121 Integrina Alpha4beta1 Interviene En Las Respuestas De La Célula Endotelial Selectiva a Thrombospondins 1 Y 2 in Vitro Y Modula La Angiogénesis in Vivo Circulation Research. Mar, 2004 | Pubmed ID: 14699013 Cáncer De Próstata Murino Basadas En MYC Comparte Características Moleculares Con Los Tumores De Próstata Humanos Cancer Cell. Sep, 2003 | Pubmed ID: 14522256 ADAMTS1: a Matrix Metalloprotease with Angioinhibitory Properties Annals of the New York Academy of Sciences. May, 2003 | Pubmed ID: 12814950 ADAMTS1/METH1 Inhibits Endothelial Cell Proliferation by Direct Binding and Sequestration of VEGF165 The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12716911 Selective Binding of Lectins to Embryonic Chicken Vasculature The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. May, 2003 | Pubmed ID: 12704207 Visualization of Advanced Human Prostate Cancer Lesions in Living Mice by a Targeted Gene Transfer Vector and Optical Imaging Nature Medicine. Aug, 2002 | Pubmed ID: 12134144 Opposing Functions of the Ets Factors NERF and ELF-1 During Chicken Blood Vessel Development Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2002 | Pubmed ID: 12117724 ADAMTS1 Cleaves Aggrecan at Multiple Sites and is Differentially Inhibited by Metalloproteinase Inhibitors Biochemical and Biophysical Research Communications. Apr, 2002 | Pubmed ID: 12054629 Expression of ADAMTS1 During Murine Development Mechanisms of Development. Jul, 2002 | Pubmed ID: 12049787 Asignación de metabolismo: Supervisar la actividad de la deshidrogenasa del lactato directamente en el tejido David Jelinek1,2, Aimee Flores1,3, Melanie Uebelhoer1, Vincent Pasque2, Kathrin Plath2,3, M. Luisa Iruela-Arispe1,3, Heather R. Christofk2,3, William E. Lowry1,3, Hilary A. Coller1,2,3 1Department of Molecular, Cell and Developmental Biology, UCLA, 2Department of Biological Chemistry, David Geffen School of Medicine, 3Molecular Biology Institute Interdepartmental Program, UCLA JoVE 57760 Biochemistry Reproducible lesión arterial Denudación por pinzamiento aórtico abdominal infrarrenal en un modelo murino Aditya S. Shirali1, Austin I. McDonald2, Julia J. Mack3, M. Luisa Iruela-Arispe3 1Department of Surgery, University of California, Los Angeles, 2Molecular Biology Institute, University of California, Los Angeles, 3Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles JoVE 54755 Medicine
Asignación de metabolismo: Supervisar la actividad de la deshidrogenasa del lactato directamente en el tejido David Jelinek1,2, Aimee Flores1,3, Melanie Uebelhoer1, Vincent Pasque2, Kathrin Plath2,3, M. Luisa Iruela-Arispe1,3, Heather R. Christofk2,3, William E. Lowry1,3, Hilary A. Coller1,2,3 1Department of Molecular, Cell and Developmental Biology, UCLA, 2Department of Biological Chemistry, David Geffen School of Medicine, 3Molecular Biology Institute Interdepartmental Program, UCLA JoVE 57760 Biochemistry
Reproducible lesión arterial Denudación por pinzamiento aórtico abdominal infrarrenal en un modelo murino Aditya S. Shirali1, Austin I. McDonald2, Julia J. Mack3, M. Luisa Iruela-Arispe3 1Department of Surgery, University of California, Los Angeles, 2Molecular Biology Institute, University of California, Los Angeles, 3Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles JoVE 54755 Medicine
