Maarten van Dinther Oncode Institute and Department of Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Maarten van Dinther has not added a biography. If you are Maarten van Dinther and would like to personalize this page please email our Author Liaison for assistance. Publications VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation Journal of Molecular Cell Biology. 02, 2020 | Pubmed ID: 31291647 Role of Soluble Endoglin in BMP9 Signaling Proceedings of the National Academy of Sciences of the United States of America. 09, 2019 | Pubmed ID: 31431534 Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension The Journal of Pathology. 11, 2019 | Pubmed ID: 31257577 USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling The EMBO Journal. 06, 2017 | Pubmed ID: 28468752 TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28115518 Determining TGF-β Receptor Levels in the Cell Membrane Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520116 Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 Gastroenterology. Jun, 2015 | Pubmed ID: 25736321 Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β Science Signaling. Jul, 2014 | Pubmed ID: 25056879 ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis PloS One. 2014 | Pubmed ID: 24489709 Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition PloS One. 2013 | Pubmed ID: 24312339 Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling PloS One. 2013 | Pubmed ID: 23638027 LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012 | Pubmed ID: 22589174 ALK2 変異患者にダウン症候群と先天性心臓欠陥します。 European Journal of Human Genetics : EJHG. Apr, 2011 | Pubmed ID: 21248739 Tgf β に対するストレス P38map 蛋白質キナーゼ-1 (MSK1) 細胞死を減衰するアクティブになります。 The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21106525 骨形成因子 (BMP)-6 媒介キー残基の同定 Noggin 阻害に抵抗できます組み換え Bmp の優れたアゴニスト活性を。 The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20048150 雑種骨化性進行性にリンクされた ALK2 R206H 突然変異を与える構成アクティビティ BMP にタイプ I 受容体および BMP 誘導骨芽細胞分化および骨形成する間葉系細胞の感受性を高めます。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010 | Pubmed ID: 19929436 オートクリン骨形成タンパク質 9 アクチビン受容体様キナーゼ-2/Smad1/Smad4 を介して卵巣癌細胞の増殖を促進する信号します。 Cancer Research. Dec, 2009 | Pubmed ID: 19996292 VEGFとTGFbeta I型受容体キナーゼの阻害剤は、相乗的にALPHA5インテグリンの発現を誘導することによって血管形成を促進 Journal of Cell Science. Sep, 2009 | Pubmed ID: 19706683 BMP-9 Signals Via ALK1 and Inhibits BFGF-induced Endothelial Cell Proliferation and VEGF-stimulated Angiogenesis Journal of Cell Science. Mar, 2007 | Pubmed ID: 17311849 腫瘍のサプレッサー細胞: Smad4 変換成長因子 β 誘発上皮間葉に転移と骨転移乳癌細胞のために必要です。 Cancer Research. Feb, 2006 | Pubmed ID: 16489022 Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. | Pubmed ID: 31857432 乳がんおよび正常細胞におけるTGF-βシグナル伝達とTGF β誘発性上皮間葉間質転移の研究 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research
乳がんおよび正常細胞におけるTGF-βシグナル伝達とTGF β誘発性上皮間葉間質転移の研究 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research