Maarten van Dinther

Publications

• VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation
  Journal of Molecular Cell Biology. 02, 2020  |   Pubmed ID: 31291647
• Role of Soluble Endoglin in BMP9 Signaling
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2019  |   Pubmed ID: 31431534
• Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension
  The Journal of Pathology. 11, 2019  |   Pubmed ID: 31257577
• USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling
  The EMBO Journal. 06, 2017  |   Pubmed ID: 28468752
• TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation
  The Journal of Biological Chemistry. Mar, 2017  |   Pubmed ID: 28115518
• Determining TGF-β Receptor Levels in the Cell Membrane
  Methods in Molecular Biology (Clifton, N.J.). 2016  |   Pubmed ID: 26520116
• Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2
  Gastroenterology. Jun, 2015  |   Pubmed ID: 25736321
• Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β
  Science Signaling. Jul, 2014  |   Pubmed ID: 25056879
• ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis
  PloS One. 2014  |   Pubmed ID: 24489709
• Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition
  PloS One. 2013  |   Pubmed ID: 24312339
• Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling
  PloS One. 2013  |   Pubmed ID: 23638027
• LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012  |   Pubmed ID: 22589174
• ALK2 Mutation in a Patient with Down's Syndrome and a Congenital Heart Defect
  European Journal of Human Genetics : EJHG. Apr, 2011  |   Pubmed ID: 21248739
• TGFbeta Activates Mitogen- and Stress-activated Protein Kinase-1 (MSK1) to Attenuate Cell Death
  The Journal of Biological Chemistry. Feb, 2011  |   Pubmed ID: 21106525
• Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity
  The Journal of Biological Chemistry. Apr, 2010  |   Pubmed ID: 20048150
• ALK2 R206H Mutation Linked to Fibrodysplasia Ossificans Progressiva Confers Constitutive Activity to the BMP Type I Receptor and Sensitizes Mesenchymal Cells to BMP-induced Osteoblast Differentiation and Bone Formation
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010  |   Pubmed ID: 19929436
• Autocrine Bone Morphogenetic Protein-9 Signals Through Activin Receptor-like Kinase-2/Smad1/Smad4 to Promote Ovarian Cancer Cell Proliferation
  Cancer Research. Dec, 2009  |   Pubmed ID: 19996292
• VEGF and Inhibitors of TGFbeta Type-I Receptor Kinase Synergistically Promote Blood-vessel Formation by Inducing Alpha5-integrin Expression
  Journal of Cell Science. Sep, 2009  |   Pubmed ID: 19706683
• BMP-9 Signals Via ALK1 and Inhibits BFGF-induced Endothelial Cell Proliferation and VEGF-stimulated Angiogenesis
  Journal of Cell Science. Mar, 2007  |   Pubmed ID: 17311849
• The Tumor Suppressor Smad4 is Required for Transforming Growth Factor Beta-induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
  Cancer Research. Feb, 2006  |   Pubmed ID: 16489022
• Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research.   |   Pubmed ID: 31857432