Manabu Tokeshi

Publications

• Dimethoxytriadinylation LC-MS/MS of Novichok A-Series Degradation Products in Human Urine
  Analytical Chemistry. Mar, 2022  |   Pubmed ID: 35253439
• Enzyme Kinetics in Confined Geometries at the Single Enzyme Level
  The Analyst. Mar, 2022  |   Pubmed ID: 35230361
• Microfluidic Technologies and Devices for Lipid Nanoparticle-based RNA Delivery
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2022  |   Pubmed ID: 35183654
• Electrochemical Enzyme-based Blood ATP and Lactate Sensor for a Rapid and Straightforward Evaluation of Illness Severity
  Biosensors & Bioelectronics. Feb, 2022  |   Pubmed ID: 34856516
• Determination of Blood Lithium-ion Concentration Using Digital Microfluidic Whole-blood Separation and Preloaded Paper Sensors
  Biosensors & Bioelectronics. Jan, 2022  |   Pubmed ID: 34571482
• One-Step Production Using a Microfluidic Device of Highly Biocompatible Size-Controlled Noncationic Exosome-like Nanoparticles for RNA Delivery
  ACS Applied Bio Materials. 02, 2021  |   Pubmed ID: 35014524
• Paper-Based Analytical Device for the On-Site Detection of Nerve Agents
  ACS Applied Bio Materials. 08, 2021  |   Pubmed ID: 35006863
• Topology-Dependent Interaction of Cyclic Poly(ethylene Glycol) Complexed with Gold Nanoparticles Against Bovine Serum Albumin for a Colorimetric Change
  Langmuir : the ACS Journal of Surfaces and Colloids. Dec, 2021  |   Pubmed ID: 34878285
• Microchip Immunoassays for Monitoring Renal Function: Rapid, Low-Cost, and Highly Sensitive Quantification of Urinary Biomarkers of Diabetic Nephropathy
  Micromachines. Oct, 2021  |   Pubmed ID: 34832765
• Facile and Rapid Detection of SARS-CoV-2 Antibody Based on a Noncompetitive Fluorescence Polarization Immunoassay in Human Serum Samples
  Biosensors & Bioelectronics. Oct, 2021  |   Pubmed ID: 34130087
• Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material
  Pharmaceutics. Apr, 2021  |   Pubmed ID: 33924589
• Simple Approach for Fluorescence Signal Amplification Utilizing a Poly(vinyl Alcohol)-Based Polymer Structure in a Microchannel
  ACS Omega. Mar, 2021  |   Pubmed ID: 33817494
• Dip-Type Paper-Based Analytical Device for Straightforward Quantitative Detection Without Precise Sample Introduction
  ACS Sensors. 03, 2021  |   Pubmed ID: 33660502
• Non-competitive Fluorescence Polarization Immunoassay for Detection of H5 Avian Influenza Virus Using a Portable Analyzer
  Analytical and Bioanalytical Chemistry. Jul, 2021  |   Pubmed ID: 33547481
• Rapid, Sensitive Universal Paper-based Device Enhances Competitive Immunoassays of Small Molecules
  Analytica Chimica Acta. Feb, 2021  |   Pubmed ID: 33453801
• Lipid Nanoparticles Loaded with Ribonucleoprotein-oligonucleotide Complexes Synthesized Using a Microfluidic Device Exhibit Robust Genome Editing and Hepatitis B Virus Inhibition
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 02, 2021  |   Pubmed ID: 33333121
• Room-temperature Crystallography Using a Microfluidic Protein Crystal Array Device and Its Application to Protein-ligand Complex Structure Analysis
  Chemical Science. Aug, 2020  |   Pubmed ID: 34094189
• Enhanced Dispersion Stability of Gold Nanoparticles by the Physisorption of Cyclic Poly(ethylene Glycol)
  Nature Communications. 11, 2020  |   Pubmed ID: 33257670
• Development of an Immuno-wall Device for the Rapid and Sensitive Detection of EGFR Mutations in Tumor Tissues Resected from Lung Cancer Patients
  PloS One. 2020  |   Pubmed ID: 33196648
• Noncompetitive Fluorescence Polarization Immunoassay for Protein Determination
  Analytical Chemistry. 11, 2020  |   Pubmed ID: 33094615
• The Use of Design of Experiments with Multiple Responses to Determine Optimal Formulations for in Vivo Hepatic MRNA Delivery
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 11, 2020  |   Pubmed ID: 32853732
• Real-Time Measurement of Protein Crystal Growth Rates Within the Microfluidic Device to Understand the Microspace Effect
  ACS Omega. Jul, 2020  |   Pubmed ID: 32715205
• Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to SiRNA Delivery
  ACS Applied Materials & Interfaces. Jul, 2020  |   Pubmed ID: 32667806
• Observation of Ethanol-Induced Condensation and Decondensation Processes at a Single-DNA Molecular Level in Microfluidic Devices Equipped with a Rapid Solution Exchange System
  Analytical Chemistry. 07, 2020  |   Pubmed ID: 32483963
• Rapid Detection of Anti-H5 Avian Influenza Virus Antibody by Fluorescence Polarization Immunoassay Using a Portable Fluorescence Polarization Analyzer
  Sensors and Actuators. B, Chemical. Aug, 2020  |   Pubmed ID: 32322135
• Paper-Based Device for the Facile Colorimetric Determination of Lithium Ions in Human Whole Blood
  ACS Sensors. 05, 2020  |   Pubmed ID: 32283919
• The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution
  Molecular Pharmaceutics. 03, 2020  |   Pubmed ID: 31990567
• Hydrophobic Scaffolds of PH-sensitive Cationic Lipids Contribute to Miscibility with Phospholipids and Improve the Efficiency of Delivering Short Interfering RNA by Small-sized Lipid Nanoparticles
  Acta Biomaterialia. 01, 2020  |   Pubmed ID: 31733331
• Rapid, Sensitive, and Selective Detection of H5 Hemagglutinin from Avian Influenza Virus Using an Immunowall Device
  ACS Omega. Oct, 2019  |   Pubmed ID: 31616851
• A Paper-based Analytical Device Coupled with Electrochemical Detection for the Determination of Dexamethasone and Prednisolone in Adulterated Traditional Medicines
  Analytica Chimica Acta. Oct, 2019  |   Pubmed ID: 31358214
• An Electrochemical Sensor Based on Structure Switching of Dithiol-modified Aptamer for Simple Detection of Ochratoxin A
  Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. Nov, 2019  |   Pubmed ID: 31327816
• High-throughput Fluorescence Polarization Immunoassay by Using a Portable Fluorescence Polarization Imaging Analyzer
  Lab on a Chip. 08, 2019  |   Pubmed ID: 31250849
• Ultrasensitive Detection of Disease Biomarkers Using an Immuno-wall Device with Enzymatic Amplification
  The Analyst. Aug, 2019  |   Pubmed ID: 31237262
• The Use of a Microfluidic Device to Encapsulate a Poorly Water-Soluble Drug CoQ in Lipid Nanoparticles and an Attempt to Regulate Intracellular Trafficking to Reach Mitochondria
  Journal of Pharmaceutical Sciences. 08, 2019  |   Pubmed ID: 30959057
• Understanding Structure-activity Relationships of PH-sensitive Cationic Lipids Facilitates the Rational Identification of Promising Lipid Nanoparticles for Delivering SiRNAs in Vivo
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 02, 2019  |   Pubmed ID: 30610950
• Development of a Microdevice for Facile Analysis of Theophylline in Whole Blood by a Cloned Enzyme Donor Immunoassay
  Lab on a Chip. 01, 2019  |   Pubmed ID: 30547178
• Development of the ILiNP Device: Fine Tuning the Lipid Nanoparticle Size Within 10 Nm for Drug Delivery
  ACS Omega. May, 2018  |   Pubmed ID: 31458718
• Recent Microdevice-Based Aptamer Sensors
  Micromachines. Apr, 2018  |   Pubmed ID: 30424135
• Microfluidic Devices for Drug Delivery Systems
  Advanced Drug Delivery Reviews. 03, 2018  |   Pubmed ID: 29908612
• Advances in Microfluidics for Lipid Nanoparticles and Extracellular Vesicles and Applications in Drug Delivery Systems
  Advanced Drug Delivery Reviews. 03, 2018  |   Pubmed ID: 29567396
• A Compact Fluorescence Polarization Analyzer with High-transmittance Liquid Crystal Layer
  The Review of Scientific Instruments. Feb, 2018  |   Pubmed ID: 29495833
• Characteristics of Microfluidic Paper-based Analytical Devices Fabricated by Four Different Methods
  Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. 2018  |   Pubmed ID: 29321455
• Understanding the Formation Mechanism of Lipid Nanoparticles in Microfluidic Devices with Chaotic Micromixers
  PloS One. 2017  |   Pubmed ID: 29182626
• Using Laser Interference Lithography in the Fabrication of a Simplified Micro- and Nanofluidic Device for Label-free Detection
  Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. 2017  |   Pubmed ID: 28993597
• A Millisecond Micro-RNA Separation Technique by a Hybrid Structure of Nanopillars and Nanoslits
  Scientific Reports. 03, 2017  |   Pubmed ID: 28272420
• Fabrication and Evaluation of Microfluidic Immunoassay Devices with Antibody-Immobilized Microbeads Retained in Porous Hydrogel Micropillars
  Methods in Molecular Biology (Clifton, N.J.). 2017  |   Pubmed ID: 28044286
• Micro/Nano Devices for Chemical Analysis
  Micromachines. Sep, 2016  |   Pubmed ID: 30404336
• Microfluidic Autologous Serum Eye-Drops Preparation As a Potential Dry Eye Treatment
  Micromachines. Jul, 2016  |   Pubmed ID: 30404287
• Advances in Microfluidic Paper-Based Analytical Devices for Food and Water Analysis
  Micromachines. May, 2016  |   Pubmed ID: 30404261
• Rapid Detection of Cat Cystatin C (cCys-C) Using Immuno-Pillar Chips
  Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. 2016  |   Pubmed ID: 27941268
• An Immuno-wall Microdevice Exhibits Rapid and Sensitive Detection of IDH1-R132H Mutation Specific to Grade II and III Gliomas
  Science and Technology of Advanced Materials. 2016  |   Pubmed ID: 27877908
• A Competitive Immunoassay System for Microfluidic Paper-based Analytical Detection of Small Size Molecules
  The Analyst. Nov, 2016  |   Pubmed ID: 27858015
• Image Analysis for a Microfluidic Paper-based Analytical Device Using the CIE L*a*b* Color System
  The Analyst. Nov, 2016  |   Pubmed ID: 27830841
• Novel Concept of Washing for Microfluidic Paper-based Analytical Devices Based on Capillary Force of Paper Substrates
  Analytical and Bioanalytical Chemistry. Nov, 2016  |   Pubmed ID: 27544520
• Label-free Detection of Real-time DNA Amplification Using a Nanofluidic Diffraction Grating
  Scientific Reports. 08, 2016  |   Pubmed ID: 27531471
• 3,3',5,5'-Tetramethylbenzidine Oxidation on Paper Devices for Horseradish Peroxidase-based Assays
  Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. 2016  |   Pubmed ID: 27506705
• Elucidation of the Physicochemical Properties and Potency of SiRNA-loaded Small-sized Lipid Nanoparticles for SiRNA Delivery
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 05, 2016  |   Pubmed ID: 26995758
• Microfluidic Approaches for Protein Crystal Structure Analysis
  Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. 2016  |   Pubmed ID: 26753699
• A Portable Liquid Chromatograph with a Battery-operated Compact Electroosmotic Pump and a Microfluidic Chip Device with a Reversed Phase Packed Column
  Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. 2015  |   Pubmed ID: 26561261
• Fluorescence Polarization Measurement System Using a Liquid Crystal Layer and an Image Sensor
  Analytical Chemistry. Oct, 2015  |   Pubmed ID: 26352939
• An Instrument-free, Screen-printed Paper Microfluidic Device That Enables Bio and Chemical Sensing
  The Analyst. Oct, 2015  |   Pubmed ID: 26207925
• A Microfluidic Cell Culture System for Monitoring of Sequential Changes in Endothelial Cells After Heat Stress
  Thrombosis Research. Aug, 2015  |   Pubmed ID: 26044666
• Arrangement of a Nanostructure Array to Control Equilibrium and Nonequilibrium Transports of Macromolecules
  Nano Letters. May, 2015  |   Pubmed ID: 25879141
• A Method of Cryoprotection for Protein Crystallography by Using a Microfluidic Chip and Its Application for in Situ X-ray Diffraction Measurements
  Analytical Chemistry. Apr, 2015  |   Pubmed ID: 25834918
• Fabrication of Functionalized Double-lamellar Multifunctional Envelope-type Nanodevices Using a Microfluidic Chip with a Chaotic Mixer Array
  PloS One. 2012  |   Pubmed ID: 22723929