Manuela Ferracin Department of Experimental, Diagnostic and Specialty Medicine - DIMES University of Bologna Biography Publications Institution JoVE Articles Manuela Ferracin has not added a biography. If you are Manuela Ferracin and would like to personalize this page please email our Author Liaison for assistance. Publications Over-expression of the MiR-483-3p Overcomes the MiR-145/TP53 Pro-apoptotic Loop in Hepatocellular Carcinoma Oncotarget. Apr, 2016 | Pubmed ID: 27120784 MiRNA Array Screening Reveals Cooperative MGMT-regulation Between MiR-181d-5p and MiR-409-3p in Glioblastoma Oncotarget. Apr, 2016 | Pubmed ID: 27057640 Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis Cell Reports. Dec, 2015 | Pubmed ID: 26686630 MicroRNA Profiling of Primary Pulmonary Enteric Adenocarcinoma in Members from the Same Family Reveals Some Similarities to Pancreatic Adenocarcinoma-a Step Towards Personalized Therapy Clinical Epigenetics. 2015 | Pubmed ID: 26677401 Circulating MicroRNAs, MiR-939, MiR-595, MiR-519d and MiR-494, Identify Cirrhotic Patients with HCC PloS One. 2015 | Pubmed ID: 26509672 MicroRNA Expression Profiling Identifies MiR-31-5p/3p As Associated with Time to Progression in Wild-type RAS Metastatic Colorectal Cancer Treated with Cetuximab Oncotarget. Nov, 2015 | Pubmed ID: 26497852 MicroRNA Profiles in Hippocampal Granule Cells and Plasma of Rats with Pilocarpine-induced Epilepsy--comparison with Human Epileptic Samples Scientific Reports. 2015 | Pubmed ID: 26382856 Micromarkers 2.0: an Update on the Role of MicroRNAs in Cancer Diagnosis and Prognosis Expert Review of Molecular Diagnostics. 2015 | Pubmed ID: 26338209 Diagnostic and Prognostic MicroRNAs in the Serum of Breast Cancer Patients Measured by Droplet Digital PCR Biomarker Research. 2015 | Pubmed ID: 26120471 Absolute Quantification of Cell-free MicroRNAs in Cancer Patients Oncotarget. Jun, 2015 | Pubmed ID: 26036630 Association Between Gene and MiRNA Expression Profiles and Stereotyped Subset #4 B-cell Receptor in Chronic Lymphocytic Leukemia Leukemia & Lymphoma. 2015 | Pubmed ID: 25860243 Increase of MicroRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins Following Mithramycin Treatment of Human Erythroid Cells PloS One. 2015 | Pubmed ID: 25849663 MicroRNAs As Biomarker of Parkinson Disease? Small but Mighty Neurology. Feb, 2015 | Pubmed ID: 25596504 Mesenchymal Progenitors Aging Highlights a MiR-196 Switch Targeting HOXB7 As Master Regulator of Proliferation and Osteogenesis Stem Cells (Dayton, Ohio). Mar, 2015 | Pubmed ID: 25428821 An Integrated Genomic-transcriptomic Approach Supports a Role for the Proto-oncogene BCL3 in Atherosclerosis Thrombosis and Haemostasis. Mar, 2015 | Pubmed ID: 25374339 Gene Expression Changes in Progression of Cervical Neoplasia Revealed by Microarray Analysis of Cervical Neoplastic Keratinocytes Journal of Cellular Physiology. Apr, 2015 | Pubmed ID: 25205602 Quantification of Circulating MiRNAs by Droplet Digital PCR: Comparison of EvaGreen- and TaqMan-based Chemistries Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Dec, 2014 | Pubmed ID: 25472671 OncomiR Detection in Circulating Body Fluids: a PDMS Microdevice Perspective Lab on a Chip. Oct, 2014 | Pubmed ID: 25178053 Identification of MiRNAs Differentially Expressed in Human Epilepsy with or Without Granule Cell Pathology PloS One. 2014 | Pubmed ID: 25148080 Involvement of the Inconstant Bursa of the Fifth Metatarsophalangeal Joint in Psoriatic Arthritis: a Clinical and Ultrasonographic Study BioMed Research International. 2014 | Pubmed ID: 25061602 MicroRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2014 | Pubmed ID: 24916701 Genetic Subclonal Complexity and MiR125a-5p Down-regulation Identify a Subset of Patients with Inferior Outcome in Low-risk CLL Patients Oncotarget. Jan, 2014 | Pubmed ID: 24334759 STAT3-mediated Activation of MicroRNA Cluster 17~92 Promotes Proliferation and Survival of ALK-positive Anaplastic Large Cell Lymphoma Haematologica. Jan, 2014 | Pubmed ID: 23975180 Epigenetic Inactivation of MiR-9 Family MicroRNAs in Chronic Lymphocytic Leukemia--implications on Constitutive Activation of NFκB Pathway Molecular Cancer. 2013 | Pubmed ID: 24373626 A Tumor-promoting Mechanism Mediated by Retrotransposon-encoded Reverse Transcriptase is Active in Human Transformed Cell Lines Oncotarget. Dec, 2013 | Pubmed ID: 24345856 MiR-125b Targets Erythropoietin and Its Receptor and Their Expression Correlates with Metastatic Potential and ERBB2/HER2 Expression Molecular Cancer. 2013 | Pubmed ID: 24165569 First Report of Circulating MicroRNAs in Tumour Necrosis Factor Receptor-associated Periodic Syndrome (TRAPS) PloS One. 2013 | Pubmed ID: 24066048 Clinical Monoclonal B Lymphocytosis Versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2013 | Pubmed ID: 24036852 CCAT2, a Novel Non-coding RNA Mapping to 8q24, Underlies Metastatic Progression and Chromosomal Instability in Colon Cancer Genome Research. Jun, 2013 | Pubmed ID: 23796952 MiR-221 Affects Multiple Cancer Pathways by Modulating the Level of Hundreds Messenger RNAs Frontiers in Genetics. 2013 | Pubmed ID: 23630541 Anti-CD38 Antibody Therapy: Windows of Opportunity Yielded by the Functional Characteristics of the Target Molecule Molecular Medicine (Cambridge, Mass.). 2013 | Pubmed ID: 23615966 MiR-126&126* Restored Expressions Play a Tumor Suppressor Role by Directly Regulating ADAM9 and MMP7 in Melanoma PloS One. 2013 | Pubmed ID: 23437250 Liver Tumorigenicity Promoted by MicroRNA-221 in a Mouse Transgenic Model Hepatology (Baltimore, Md.). Sep, 2012 | Pubmed ID: 22473819 MiR-34a Predicts Survival of Ewing's Sarcoma Patients and Directly Influences Cell Chemo-sensitivity and Malignancy The Journal of Pathology. Apr, 2012 | Pubmed ID: 21960059 MicroRNAs: Toward the Clinic for Breast Cancer Patients Seminars in Oncology. Dec, 2011 | Pubmed ID: 22082762 MicroRNA Profiling for the Identification of Cancers with Unknown Primary Tissue-of-origin The Journal of Pathology. Sep, 2011 | Pubmed ID: 21630269 Mutated Beta-catenin Evades a MicroRNA-dependent Regulatory Loop Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21383185 MicroRNAs Dysregulation in Human Malignant Pleural Mesothelioma Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. May, 2011 | Pubmed ID: 21358347 Altered MiRNA Expression in T Regulatory Cells in Course of Multiple Sclerosis Journal of Neuroimmunology. Sep, 2010 | Pubmed ID: 20637509 Resveratrol Decreases the Levels of MiR-155 by Upregulating MiR-663, a MicroRNA Targeting JunB and JunD Carcinogenesis. Sep, 2010 | Pubmed ID: 20622002 MicroRNAs Involvement in Fludarabine Refractory Chronic Lymphocytic Leukemia Molecular Cancer. 2010 | Pubmed ID: 20504344 Oncogenic Role of MiR-483-3p at the IGF2/483 Locus Cancer Research. Apr, 2010 | Pubmed ID: 20388800 Micromarkers: MiRNAs in Cancer Diagnosis and Prognosis Expert Review of Molecular Diagnostics. Apr, 2010 | Pubmed ID: 20370587 Modulation of Mismatch Repair and Genomic Stability by MiR-155 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20351277 Differential Cytogenomics and MiRNA Signature of the Acute Myeloid Leukaemia Kasumi-1 Cell Line CD34+38- Compartment Leukemia Research. Oct, 2010 | Pubmed ID: 20227111 Non-coding RNAs Change Their Expression Profile After Retinoid Induced Differentiation of the Promyelocytic Cell Line NB4 BMC Research Notes. 2010 | Pubmed ID: 20181027 MicroRNA Fingerprints Identify MiR-150 As a Plasma Prognostic Marker in Patients with Sepsis PloS One. 2009 | Pubmed ID: 19823581 Karyotype-specific MicroRNA Signature in Chronic Lymphocytic Leukemia Blood. Oct, 2009 | Pubmed ID: 19717645 MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2009 | Pubmed ID: 19671867 MiR-122/cyclin G1 Interaction Modulates P53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells Cancer Research. Jul, 2009 | Pubmed ID: 19584283 Altered Expression of Selected MicroRNAs in Melanoma: Antiproliferative and Proapoptotic Activity of MiRNA-155 International Journal of Oncology. Aug, 2009 | Pubmed ID: 19578755 MicroRNA Expression Changes During Human Leukemic HL-60 Cell Differentiation Induced by 4-hydroxynonenal, a Product of Lipid Peroxidation Free Radical Biology & Medicine. Jan, 2009 | Pubmed ID: 19022373 Isolation and Characterization of CD146+ Multipotent Mesenchymal Stromal Cells Experimental Hematology. Aug, 2008 | Pubmed ID: 18504067 MiR-15a and MiR-16-1 Cluster Functions in Human Leukemia Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008 | Pubmed ID: 18362358 Micro-RNA Profiling in Kidney and Bladder Cancers Urologic Oncology. Sep-Oct, 2007 | Pubmed ID: 17826655 Ultraconserved Regions Encoding NcRNAs Are Altered in Human Leukemias and Carcinomas Cancer Cell. Sep, 2007 | Pubmed ID: 17785203 MRNA/microRNA Gene Expression Profile in Microsatellite Unstable Colorectal Cancer Molecular Cancer. 2007 | Pubmed ID: 17716371 Tumor Suppressor Functions of ARLTS1 in Lung Cancers Cancer Research. Aug, 2007 | Pubmed ID: 17699778 Cyclin G1 is a Target of MiR-122a, a MicroRNA Frequently Down-regulated in Human Hepatocellular Carcinoma Cancer Research. Jul, 2007 | Pubmed ID: 17616664 Regulation of MicroRNA Expression: the Hypoxic Component Cell Cycle (Georgetown, Tex.). Jun, 2007 | Pubmed ID: 17582223 MicroRNAs in Human Cancer: from Research to Therapy Journal of Cell Science. Jun, 2007 | Pubmed ID: 17515481 A MicroRNA Signature of Hypoxia Molecular and Cellular Biology. Mar, 2007 | Pubmed ID: 17194750 Identification of Differentially Expressed MicroRNAs by Microarray: a Possible Role for MicroRNA Genes in Pituitary Adenomas Journal of Cellular Physiology. Feb, 2007 | Pubmed ID: 17111382 A MicroRNA Expression Signature of Human Solid Tumors Defines Cancer Gene Targets Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16461460 A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia The New England Journal of Medicine. Oct, 2005 | Pubmed ID: 16251535 MiR-15 and MiR-16 Induce Apoptosis by Targeting BCL2 Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005 | Pubmed ID: 16166262 MicroRNA Gene Expression Deregulation in Human Breast Cancer Cancer Research. Aug, 2005 | Pubmed ID: 16103053 Familial Cancer Associated with a Polymorphism in ARLTS1 The New England Journal of Medicine. Apr, 2005 | Pubmed ID: 15843669 MicroRNA Profiling Reveals Distinct Signatures in B Cell Chronic Lymphocytic Leukemias Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15284443 An Oligonucleotide Microchip for Genome-wide MicroRNA Profiling in Human and Mouse Tissues Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15210942 Circulating MicroRNA Quantification Using DNA-binding Dye Chemistry and Droplet Digital PCR Manuela Ferracin1, Irene Salamon2, Laura Lupini2, Elena Miotto2, Silvia Sabbioni3, Massimo Negrini4 1Department of Experimental, Diagnostic and Specialty Medicine - DIMES, University of Bologna, 2Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, 3Department of Life Sciences and Biotechnology, University of Ferrara, 4Department of Morphology, Surgery and Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara JoVE 54102 Bioengineering
Circulating MicroRNA Quantification Using DNA-binding Dye Chemistry and Droplet Digital PCR Manuela Ferracin1, Irene Salamon2, Laura Lupini2, Elena Miotto2, Silvia Sabbioni3, Massimo Negrini4 1Department of Experimental, Diagnostic and Specialty Medicine - DIMES, University of Bologna, 2Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, 3Department of Life Sciences and Biotechnology, University of Ferrara, 4Department of Morphology, Surgery and Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara JoVE 54102 Bioengineering
