Marcelo Jacobs-Lorena Johns Hopkins Malaria Research Institute Johns Hopkins Bloomberg School of Public Health Biography Publications Institution JoVE Articles Marcelo Jacobs-Lorena has not added a biography. If you are Marcelo Jacobs-Lorena and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Key Determinants of Cerebral Malaria Development and Inhibition Pathways MBio. Jan, 2022 | Pubmed ID: 35073748 Plasmodium Sporozoite Phospholipid Scramblase Interacts with Mammalian Carbamoyl-phosphate Synthetase 1 to Infect Hepatocytes Nature Communications. 11, 2021 | Pubmed ID: 34799567 A Genetically Modified Anti-Plasmodium Bacterium Is Harmless to the Foragers of the Stingless Bee Partamona Helleri Microbial Ecology. Jul, 2021 | Pubmed ID: 34231036 The Fibrinolytic System Enables the Onset of Infection in the Mosquito Vector and the Mammalian Host Science Advances. Feb, 2021 | Pubmed ID: 33547079 Clock Genes and Environmental Cues Coordinate Pheromone Synthesis, Swarming, and Mating Science (New York, N.Y.). 01, 2021 | Pubmed ID: 33479155 Self-limiting Paratransgenesis PLoS Neglected Tropical Diseases. 08, 2020 | Pubmed ID: 32810151 The Response of Plasmodium Falciparum to Isoleucine Withdrawal is Dependent on the Stage of Progression Through the Intraerythrocytic Cell Cycle Malaria Journal. Apr, 2020 | Pubmed ID: 32268910 Use of Microbiota to Fight Mosquito-Borne Disease Frontiers in Genetics. 2020 | Pubmed ID: 32211030 Transcriptional Profiling and Physiological Roles of Aedes Aegypti Spermathecal-related Genes BMC Genomics. Feb, 2020 | Pubmed ID: 32041546 A Key Fits a Mosquito Lock Proceedings of the National Academy of Sciences of the United States of America. 02, 2020 | Pubmed ID: 32024758 Mosquito Microbiota and Implications for Disease Control Trends in Parasitology. 02, 2020 | Pubmed ID: 31866183 CXCR4 Regulates Development in Mouse and Human Hepatocytes The Journal of Experimental Medicine. 08, 2019 | Pubmed ID: 31189656 Identification of GAPDH Epitopes for Generation of Antibodies That Inhibit Malaria Infection Life Science Alliance. Oct, 2018 | Pubmed ID: 30456380 Field Assessment of Potential Sugar Feeding Stations for Disseminating Bacteria in a Paratransgenic Approach to Control Malaria Malaria Journal. Oct, 2018 | Pubmed ID: 30333029 Driving Mosquito Refractoriness to with Engineered Symbiotic Bacteria Science (New York, N.Y.). 09, 2017 | Pubmed ID: 28963255 Confers Survival Upon Amino Acid Starvation MBio. 03, 2017 | Pubmed ID: 28351924 Identification of GAPDH on the Surface of Plasmodium Sporozoites As a New Candidate for Targeting Malaria Liver Invasion The Journal of Experimental Medicine. 09, 2016 | Pubmed ID: 27551151 Species-specific Escape of Plasmodium Sporozoites from Oocysts of Avian, Rodent, and Human Malarial Parasites Malaria Journal. Aug, 2016 | Pubmed ID: 27480269 Genetic Control Of Malaria Mosquitoes Trends in Parasitology. Mar, 2016 | Pubmed ID: 26809567 Hemocyte Differentiation Mediates the Mosquito Late-phase Immune Response Against Plasmodium in Anopheles Gambiae Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 26080400 Malaria Parasite Pfs47 Disrupts JNK Signaling to Escape Mosquito Immunity Proceedings of the National Academy of Sciences of the United States of America. Feb, 2015 | Pubmed ID: 25617364 The Plasmodium Bottleneck: Malaria Parasite Losses in the Mosquito Vector Memorias Do Instituto Oswaldo Cruz. Aug, 2014 | Pubmed ID: 25185005 Transgenic Mosquitoes Expressing a Phospholipase A(2) Gene Have a Fitness Advantage when Fed Plasmodium Falciparum-infected Blood PloS One. 2013 | Pubmed ID: 24098427 Enterobacter-activated Mosquito Immune Responses to Plasmodium Involve Activation of SRPN6 in Anopheles Stephensi PloS One. 2013 | Pubmed ID: 23658788 Transposon Mutagenesis Identifies Genes Essential for Plasmodium Falciparum Gametocytogenesis Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23572579 Genetic Approaches to Interfere with Malaria Transmission by Vector Mosquitoes Trends in Biotechnology. Mar, 2013 | Pubmed ID: 23395485 Regulation of Anti-Plasmodium Immunity by a LITAF-like Transcription Factor in the Malaria Vector Anopheles Gambiae PLoS Pathogens. 2012 | Pubmed ID: 23093936 Fighting Malaria with Engineered Symbiotic Bacteria from Vector Mosquitoes Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22802646 Plasmodium Ookinetes Coopt Mammalian Plasminogen to Invade the Mosquito Midgut Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21949403 Surface-expressed Enolases of Plasmodium and Other Pathogens Memorias Do Instituto Oswaldo Cruz. Aug, 2011 | Pubmed ID: 21881761 -Mosquito Interactions: A Tale of Roadblocks and Detours Advances in Insect Physiology. 2010 | Pubmed ID: 23729903 Plasmodium Sporozoite Invasion of the Mosquito Salivary Gland Current Opinion in Microbiology. Aug, 2009 | Pubmed ID: 19608457 Anopheles Gambiae Croquemort SCRBQ2, Expression Profile in the Mosquito and Its Potential Interaction with the Malaria Parasite Plasmodium Berghei Insect Biochemistry and Molecular Biology. May-Jun, 2009 | Pubmed ID: 19366631 Flipping the Paradigm on Malaria Transmission-blocking Vaccines Trends in Parasitology. Aug, 2008 | Pubmed ID: 18599352 Plasmodium Falciparum Ookinetes Require Mosquito Midgut Chondroitin Sulfate Proteoglycans for Cell Invasion Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17873063 Disruption of Plasmodium Falciparum Development by Antibodies Against a Conserved Mosquito Midgut Antigen Proceedings of the National Academy of Sciences of the United States of America. Aug, 2007 | Pubmed ID: 17673553 Identification of the Aedes Aegypti Peritrophic Matrix Protein AeIMUCI As a Heme-binding Protein Biochemistry. Aug, 2006 | Pubmed ID: 16878988 Entomopathogenic Fungi As Biological Insecticides to Control Malaria Trends in Parasitology. Feb, 2006 | Pubmed ID: 16377249 Insight into a Conserved Lifestyle: Protein-carbohydrate Adhesion Strategies of Vector-borne Pathogens Infection and Immunity. Dec, 2005 | Pubmed ID: 16299269 An Immune-responsive Serpin, SRPN6, Mediates Mosquito Defense Against Malaria Parasites Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16260729 מתן יעיל של הפרעת RNA דרך הפה (RNAi) ליתושים אנופלס גמביה בוגרים Mabel Taracena1,2, Catherine Hunt1, Pamela Pennington3, Deborah Andrew4,5, Marcelo Jacobs-Lorena5,6, Ellen Dotson1, Michael Wells5,7,8 1Division of Parasitic Diseases and Malaria, Entomology Branch, Centers for Disease Control and Prevention, 2Department of Entomology, Cornell University, 3Centro de Estudios en Biotecnologia, Universidad del Valle de Guatemala, 4Department of Cell Biology, Johns Hopkins School of Medicine, 5Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, 6Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health and Malaria Research Institute, 7Department of Cell Biology, Johns Hopkins School of Medicine, 8Biomedical Sciences Department, Idaho College of Osteopathic Medicine JoVE 63266 Biology
מתן יעיל של הפרעת RNA דרך הפה (RNAi) ליתושים אנופלס גמביה בוגרים Mabel Taracena1,2, Catherine Hunt1, Pamela Pennington3, Deborah Andrew4,5, Marcelo Jacobs-Lorena5,6, Ellen Dotson1, Michael Wells5,7,8 1Division of Parasitic Diseases and Malaria, Entomology Branch, Centers for Disease Control and Prevention, 2Department of Entomology, Cornell University, 3Centro de Estudios en Biotecnologia, Universidad del Valle de Guatemala, 4Department of Cell Biology, Johns Hopkins School of Medicine, 5Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, 6Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health and Malaria Research Institute, 7Department of Cell Biology, Johns Hopkins School of Medicine, 8Biomedical Sciences Department, Idaho College of Osteopathic Medicine JoVE 63266 Biology