Margaret Fischl Division of Infectious Diseases Miller School of Medicine, University of Miami Biography Publications Institution JoVE Articles Margaret Fischl has not added a biography. If you are Margaret Fischl and would like to personalize this page please email our Author Liaison for assistance. Publications Smoking, HIV, and Risk of Pregnancy Loss AIDS (London, England). Feb, 2017 | Pubmed ID: 27902507 High Levels of Inflammatory Cytokines in the Reproductive Tract of Women with BV and Engaging in Intravaginal Douching: A Cross-Sectional Study of Participants in the Women Interagency HIV Study AIDS Research and Human Retroviruses. Jan, 2017 | Pubmed ID: 27897054 Increased Glucose Transporter-1 Expression on Intermediate Monocytes from HIV-infected Women with Subclinical Cardiovascular Disease AIDS (London, England). Jan, 2017 | Pubmed ID: 27835618 Behaviorally and Perinatally HIV-infected Young Women: Targets for Preconception Counseling AIDS Care. Mar, 2017 | Pubmed ID: 27535165 Bacterial Vaginosis Is Associated with Loss of Gamma Delta T Cells in the Female Reproductive Tract in Women in the Miami Women Interagency HIV Study (WIHS): A Cross Sectional Study PloS One. 2016 | Pubmed ID: 27078021 A Therapeutic HIV-1 Vaccine Enhances Anti-HIV-1 Immune Responses in Patients Under Highly Active Antiretroviral Therapy Vaccine. Apr, 2016 | Pubmed ID: 27002500 Repeated Cycles of Recombinant Human Interleukin 7 in HIV-Infected Patients With Low CD4 T-Cell Reconstitution on Antiretroviral Therapy: Results of 2 Phase II Multicenter Studies Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. May, 2016 | Pubmed ID: 26908786 Lipid-Lowering Therapy in HIV-Infected Patients: Relationship with Antiretroviral Agents and Impact of Substance-Related Disorders Current Vascular Pharmacology. 2016 | Pubmed ID: 26733388 Loss of Intra-Epithelial Endocervical Gamma Delta (GD) 1 T Cells in HIV-Infected Women American Journal of Reproductive Immunology (New York, N.Y. : 1989). Feb, 2016 | Pubmed ID: 26666220 Peripheral T Follicular Helper Cells Are the Major HIV Reservoir Within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy Journal of Virology. Dec, 2015 | Pubmed ID: 26676775 A Cross-sectional Study of Bacterial Vaginosis, Intravaginal Practices and HIV Genital Shedding; Implications for HIV Transmission and Women's Health BMJ Open. Nov, 2015 | Pubmed ID: 26553833 Cervical Precancer Risk in HIV-Infected Women Who Test Positive for Oncogenic Human Papillomavirus Despite a Normal Pap Test Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Nov, 2015 | Pubmed ID: 26187020 HIV Infection Worsens Age-Associated Defects in Antibody Responses to Influenza Vaccine The Journal of Infectious Diseases. Jun, 2015 | Pubmed ID: 25556252 Sex Differences in Atazanavir Pharmacokinetics and Associations with Time to Clinical Events: AIDS Clinical Trials Group Study A5202 The Journal of Antimicrobial Chemotherapy. Dec, 2014 | Pubmed ID: 25159623 Safety and Efficacy of the Peptide-based Therapeutic Vaccine for HIV-1, Vacc-4x: a Phase 2 Randomised, Double-blind, Placebo-controlled Trial The Lancet. Infectious Diseases. Apr, 2014 | Pubmed ID: 24525316 Decreases in Colonic and Systemic Inflammation in Chronic HIV Infection After IL-7 Administration PLoS Pathogens. Jan, 2014 | Pubmed ID: 24497828 Outcomes by Sex Following Treatment Initiation with Atazanavir Plus Ritonavir or Efavirenz with Abacavir/lamivudine or Tenofovir/emtricitabine Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2014 | Pubmed ID: 24253247 Early Virologic Response to Abacavir/lamivudine and Tenofovir/emtricitabine During ACTG A5202 HIV Clinical Trials. Nov-Dec, 2013 | Pubmed ID: 24334181 Impaired Antibody Response to Influenza Vaccine in HIV-infected and Uninfected Aging Women is Associated with Immune Activation and Inflammation PloS One. 2013 | Pubmed ID: 24236161 Racial Differences in Response to Antiretroviral Therapy for HIV Infection: an AIDS Clinical Trials Group (ACTG) Study Analysis Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Dec, 2013 | Pubmed ID: 24046302 Combination Antiretroviral Therapy with Raltegravir Leads to Rapid Immunologic Reconstitution in Treatment-naive Patients with Chronic HIV Infection The Journal of Infectious Diseases. Nov, 2013 | Pubmed ID: 23922374 Immune Activation in HIV-infected Aging Women on Antiretrovirals--implications for Age-associated Comorbidities: a Cross-sectional Pilot Study PloS One. 2013 | Pubmed ID: 23724003 Impact of UGT1A1 Gilbert Variant on Discontinuation of Ritonavir-boosted Atazanavir in AIDS Clinical Trials Group Study A5202 The Journal of Infectious Diseases. Feb, 2013 | Pubmed ID: 23148286 HIV-1 Amino Acid Changes Among Participants with Virologic Failure: Associations with First-line Efavirenz or Atazanavir Plus Ritonavir and Disease Status The Journal of Infectious Diseases. Dec, 2012 | Pubmed ID: 23148287 Impaired Peripheral Blood T-follicular Helper Cell Function in HIV-infected Nonresponders to the 2009 H1N1/09 Vaccine Blood. Aug, 2012 | Pubmed ID: 22692510 Abacavir/lamivudine Versus Tenofovir DF/emtricitabine As Part of Combination Regimens for Initial Treatment of HIV: Final Results The Journal of Infectious Diseases. Oct, 2011 | Pubmed ID: 21917892 Innate Immune Defects Correlate with Failure of Antibody Responses to H1N1/09 Vaccine in HIV-infected Patients The Journal of Allergy and Clinical Immunology. Dec, 2011 | Pubmed ID: 21752440 Therapeutic Drug Monitoring of Protease Inhibitors and Efavirenz in HIV-infected Individuals with Active Substance-related Disorders Therapeutic Drug Monitoring. Jun, 2011 | Pubmed ID: 21544014 Upregulation of IL-21 Receptor on B Cells and IL-21 Secretion Distinguishes Novel 2009 H1N1 Vaccine Responders from Nonresponders Among HIV-infected Persons on Combination Antiretroviral Therapy Journal of Immunology (Baltimore, Md. : 1950). Jun, 2011 | Pubmed ID: 21531891 Atazanavir Plus Ritonavir or Efavirenz As Part of a 3-drug Regimen for Initial Treatment of HIV-1 Annals of Internal Medicine. Apr, 2011 | Pubmed ID: 21320923 Preclinical Evaluation of HIV-1 Therapeutic Ex Vivo Dendritic Cell Vaccines Expressing Consensus Gag Antigens and Conserved Gag Epitopes Vaccine. Mar, 2011 | Pubmed ID: 21241732 HIV-1 Viruses Detected During Episodic Blips Following Interleukin-7 Administration Are Similar to the Viruses Present Before and After Interleukin-7 Therapy AIDS (London, England). Jan, 2011 | Pubmed ID: 21124203 A Randomized, Placebo-controlled Trial of Abacavir Intensification in HIV-1-infected Adults with Virologic Suppression on a Protease Inhibitor-containing Regimen HIV Clinical Trials. Nov-Dec, 2010 | Pubmed ID: 21239359 Immune Exhaustion Occurs Concomitantly with Immune Activation and Decrease in Regulatory T Cells in Viremic Chronically HIV-1-infected Patients Journal of Acquired Immune Deficiency Syndromes (1999). Aug, 2010 | Pubmed ID: 20463584 Impact of Low Abundance HIV Variants on Response to Ritonavir-boosted Atazanavir or Fosamprenavir Given Once Daily with Tenofovir/emtricitabine in Antiretroviral-naive HIV-infected Patients AIDS Research and Human Retroviruses. Apr, 2010 | Pubmed ID: 20380480 Abacavir-lamivudine Versus Tenofovir-emtricitabine for Initial HIV-1 Therapy The New England Journal of Medicine. Dec, 2009 | Pubmed ID: 19952143 The Challenge of HIV-1 Genetic Diversity: Discordant CD4+ T-Cell Count and Viral Load in an Untreated Patient Infected with a Subtype F Strain Journal of Acquired Immune Deficiency Syndromes (1999). Dec, 2009 | Pubmed ID: 19935211 IL-7 Administration Drives T Cell-cycle Entry and Expansion in HIV-1 Infection Blood. Jun, 2009 | Pubmed ID: 19380868 Antiviral Activity of Single-dose PRO 140, a CCR5 Monoclonal Antibody, in HIV-infected Adults The Journal of Infectious Diseases. Nov, 2008 | Pubmed ID: 18771406 Antiretroviral Treatment of Adult HIV Infection: 2008 Recommendations of the International AIDS Society-USA Panel JAMA. Aug, 2008 | Pubmed ID: 18677028 Fosamprenavir or Atazanavir Once Daily Boosted with Ritonavir 100 Mg, Plus Tenofovir/emtricitabine, for the Initial Treatment of HIV Infection: 48-week Results of ALERT AIDS Research and Therapy. Mar, 2008 | Pubmed ID: 18373851 Association of Efavirenz Hypersusceptibility with Virologic Response in ACTG 368, a Randomized Trial of Abacavir (ABC) in Combination with Efavirenz (EFV) and Indinavir (IDV) in HIV-infected Subjects with Prior Nucleoside Analog Experience HIV Clinical Trials. Jan-Feb, 2008 | Pubmed ID: 18215978 Factors Associated with Altered Pharmacokinetics in Substance Users and Non-substance Users Receiving Lopinavir and Atazanavir The American Journal on Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. Nov-Dec, 2007 | Pubmed ID: 18058416 Intracellular Nucleoside Triphosphate Concentrations in HIV-infected Patients on Dual Nucleoside Reverse Transcriptase Inhibitor Therapy Antiviral Therapy. 2007 | Pubmed ID: 17926654 Assessing the Impact of Substance Use and Hepatitis Coinfection on Atazanavir and Lopinavir Trough Concentrations in HIV-infected Patients During Therapeutic Drug Monitoring Therapeutic Drug Monitoring. Oct, 2007 | Pubmed ID: 17898644 Attitudes and Perceptions of AIDS Clinical Trials Group Site Coordinators on HIV Clinical Trial Recruitment and Retention: a Descriptive Study AIDS Patient Care and STDs. Aug, 2007 | Pubmed ID: 17711380 Switching to a Protease Inhibitor-containing, Nucleoside-sparing Regimen (lopinavir/ritonavir Plus Efavirenz) Increases Limb Fat but Raises Serum Lipid Levels: Results of a Prospective Randomized Trial (AIDS Clinical Trial Group 5125s) Journal of Acquired Immune Deficiency Syndromes (1999). Jun, 2007 | Pubmed ID: 17527093 Buprenorphine Assay and Plasma Concentration Monitoring in HIV-infected Substance Users Journal of Pharmaceutical and Biomedical Analysis. May, 2007 | Pubmed ID: 17391891 Multidrug Resistance 1 Polymorphisms and Trough Concentrations of Atazanavir and Lopinavir in Patients with HIV Pharmacogenomics. Mar, 2007 | Pubmed ID: 17324111 Integration of Atazanavir into an Existing Liquid Chromatography UV Method for Protease Inhibitors: Validation and Application Therapeutic Drug Monitoring. Feb, 2007 | Pubmed ID: 17304157 Randomized Open-label Trial of Two Simplified, Class-sparing Regimens Following a First Suppressive Three or Four-drug Regimen AIDS (London, England). Jan, 2007 | Pubmed ID: 17255739 A Randomized, Partially Blinded Phase 2 Trial of Antiretroviral Therapy, HIV-specific Immunizations, and Interleukin-2 Cycles to Promote Efficient Control of Viral Replication (ACTG A5024) The Journal of Infectious Diseases. Dec, 2006 | Pubmed ID: 17109338 Treatment for Adult HIV Infection: 2006 Recommendations of the International AIDS Society--USA Panel Topics in HIV Medicine : a Publication of the International AIDS Society, USA. Aug-Sep, 2006 | Pubmed ID: 17016878 Treatment for Adult HIV Infection: 2006 Recommendations of the International AIDS Society-USA Panel JAMA : the Journal of the American Medical Association. Aug, 2006 | Pubmed ID: 16905788 Interferon-alpha2b with Protease Inhibitor-based Antiretroviral Therapy in Patients with AIDS-associated Kaposi Sarcoma: an AIDS Malignancy Consortium Phase I Trial Journal of Acquired Immune Deficiency Syndromes (1999). Feb, 2006 | Pubmed ID: 16394845 A Randomized Study of Serial Telephone Call Support to Increase Adherence and Thereby Improve Virologic Outcome in Persons Initiating Antiretroviral Therapy The Journal of Infectious Diseases. Oct, 2005 | Pubmed ID: 16170757 Pharmacokinetics of Nelfinavir and Efavirenz in Antiretroviral-naive, Human Immunodeficiency Virus-infected Subjects when Administered Alone or in Combination with Nucleoside Analog Reverse Transcriptase Inhibitors Antimicrobial Agents and Chemotherapy. Aug, 2005 | Pubmed ID: 16048984 Population Pharmacokinetics of Delavirdine and N-delavirdine in HIV-infected Individuals Clinical Pharmacokinetics. 2005 | Pubmed ID: 15634033 HIV-1 Drug Resistance in Subjects with Advanced HIV-1 Infection in Whom Antiretroviral Combination Therapy is Failing: a Substudy of AIDS Clinical Trials Group Protocol 388 Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Aug, 2004 | Pubmed ID: 15356820 Treatment for Adult HIV Infection: 2004 Recommendations of the International AIDS Society-USA Panel JAMA : the Journal of the American Medical Association. Jul, 2004 | Pubmed ID: 15249575 Pharmacokinetics of Indinavir and Nelfinavir in Treatment-naive, Human Immunodeficiency Virus-infected Subjects Antimicrobial Agents and Chemotherapy. Mar, 2004 | Pubmed ID: 14982784 Association of T Cell Proliferative Responses and Phenotype with Virus Control in Chronic Progressive HIV-1 Disease The Journal of Infectious Diseases. Feb, 2004 | Pubmed ID: 14745710 Effect of Food on the Steady-State Pharmacokinetics of Delavirdine in Patients with HIV Infection Clinical Drug Investigation. 2003 | Pubmed ID: 17535038 A Randomized Trial of Nelfinavir and Abacavir in Combination with Efavirenz and Adefovir Dipivoxil in HIV-1-infected Persons with Virological Failure Receiving Indinavir Antiviral Therapy. Dec, 2003 | Pubmed ID: 14760884 Comparison of Sequential Three-drug Regimens As Initial Therapy for HIV-1 Infection The New England Journal of Medicine. Dec, 2003 | Pubmed ID: 14668455 Twice-daily Trizivir Versus Combivir-abacavir in Antiretroviral-experienced Adults with Human Immunodeficiency Virus-1 Infection: a Formulation-switch Trial Pharmacotherapy. Nov, 2003 | Pubmed ID: 14620390 Long-term Efficacy, Safety, and Tolerability of Indinavir-based Therapy in Protease Inhibitor-naive Adults with Advanced HIV Infection Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Oct, 2003 | Pubmed ID: 14523778 A Randomized Trial of 2 Different 4-drug Antiretroviral Regimens Versus a 3-drug Regimen, in Advanced Human Immunodeficiency Virus Disease The Journal of Infectious Diseases. Sep, 2003 | Pubmed ID: 12934177 Indinavir, Efavirenz, and Abacavir Pharmacokinetics in Human Immunodeficiency Virus-infected Subjects Antimicrobial Agents and Chemotherapy. Jun, 2003 | Pubmed ID: 12760869 Open-label Study of a Twice-daily Indinavir 800-mg/ritonavir 100-mg Regimen in Protease Inhibitor-naive HIV-infected Adults Journal of Acquired Immune Deficiency Syndromes (1999). Dec, 2002 | Pubmed ID: 12473835 Durability of Response to Treatment Among Antiretroviral-experienced Subjects: 48-week Results from AIDS Clinical Trials Group Protocol 359 The Journal of Infectious Diseases. Sep, 2002 | Pubmed ID: 12195349 Antiretroviral Treatment for Adult HIV Infection in 2002: Updated Recommendations of the International AIDS Society-USA Panel JAMA : the Journal of the American Medical Association. Jul, 2002 | Pubmed ID: 12095387 Detection of Replication-competent Human Immunodeficiency Virus Type 1 (HIV-1) in Cultures from Patients with Levels of HIV-1 RNA in Plasma Suppressed to Less Than 500 or 50 Copies Per Milliliter Journal of Clinical Microbiology. Jun, 2002 | Pubmed ID: 12037070 Mutations in HIV-1 Reverse Transcriptase During Therapy with Abacavir, Lamivudine and Zidovudine in HIV-1-infected Adults with No Prior Antiretroviral Therapy Antiviral Therapy. Mar, 2002 | Pubmed ID: 12008787 Response to Lamivudine-zidovudine Plus Abacavir Twice Daily in Antiretroviral-naive, Incarcerated Patients with HIV Infection Taking Directly Observed Treatment Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2002 | Pubmed ID: 11797179 Isolation and Flow Cytometric Analysis of Human Endocervical Gamma Delta T Cells Natasa Strbo1, Laura Romero1, Maria Alcaide2, Margaret Fischl2 1Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, 2Division of Infectious Diseases, Miller School of Medicine, University of Miami JoVE 55038 Immunology and Infection
Isolation and Flow Cytometric Analysis of Human Endocervical Gamma Delta T Cells Natasa Strbo1, Laura Romero1, Maria Alcaide2, Margaret Fischl2 1Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, 2Division of Infectious Diseases, Miller School of Medicine, University of Miami JoVE 55038 Immunology and Infection