Maria E. Figueroa

Publications

• Musashi2 Sustains the Mixed-lineage Leukemia-driven Stem Cell Regulatory Program
  The Journal of Clinical Investigation. Feb, 2015  |   Pubmed ID: 25664853
• Plasticity of DNA Methylation in a Nerve Injury Model of Pain
  Epigenetics : Official Journal of the DNA Methylation Society. Jan, 2015  |   Pubmed ID: 25621511
• Validation of DNA Methylation to Predict Outcome in Acute Myeloid Leukemia by Use of XMELP
  Clinical Chemistry. Jan, 2015  |   Pubmed ID: 25348669
• Epigenetic Deregulation in Myeloid Malignancies
  Translational Research : the Journal of Laboratory and Clinical Medicine. Jan, 2015  |   Pubmed ID: 24813528
• DNA Hydroxymethylation Profiling Reveals That WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia
  Cell Reports. Dec, 2014  |   Pubmed ID: 25482556
• MethylSig: a Whole Genome DNA Methylation Analysis Pipeline
  Bioinformatics (Oxford, England). Sep, 2014  |   Pubmed ID: 24836530
• Two Splice-factor Mutant Leukemia Subgroups Uncovered at the Boundaries of MDS and AML Using Combined Gene Expression and DNA-methylation Profiling
  Blood. May, 2014  |   Pubmed ID: 24668493
• Prolonged Administration of Azacitidine with or Without Entinostat for Myelodysplastic Syndrome and Acute Myeloid Leukemia with Myelodysplasia-related Changes: Results of the US Leukemia Intergroup Trial E1905
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2014  |   Pubmed ID: 24663049
• Microsphere-based Multiplex Analysis of DNA Methylation in Acute Myeloid Leukemia
  The Journal of Molecular Diagnostics : JMD. Mar, 2014  |   Pubmed ID: 24373919
• PRMT4 Blocks Myeloid Differentiation by Assembling a Methyl-RUNX1-dependent Repressor Complex
  Cell Reports. Dec, 2013  |   Pubmed ID: 24332853
• Epigenetic Roles of MLL Oncoproteins Are Dependent on NF-κB
  Cancer Cell. Oct, 2013  |   Pubmed ID: 24054986
• Development of Acute Megakaryoblastic Leukemia in Down Syndrome is Associated with Sequential Epigenetic Changes
  Blood. Oct, 2013  |   Pubmed ID: 23980066
• Integrated Genetic and Epigenetic Analysis of Childhood Acute Lymphoblastic Leukemia
  The Journal of Clinical Investigation. Jul, 2013  |   Pubmed ID: 23921123
• Understanding and Utilizing New Molecular Genetics in MDS
  Clinical Advances in Hematology & Oncology : H&O. Feb, 2013  |   Pubmed ID: 23598913
• Satb1 Regulates the Self-renewal of Hematopoietic Stem Cells by Promoting Quiescence and Repressing Differentiation Commitment
  Nature Immunology. May, 2013  |   Pubmed ID: 23563689
• Notch Activation Inhibits AML Growth and Survival: a Potential Therapeutic Approach
  The Journal of Experimental Medicine. Feb, 2013  |   Pubmed ID: 23359069
• Interpreting New Molecular Genetics in Myelodysplastic Syndromes
  Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2012  |   Pubmed ID: 23233561
• C/EBPγ Deregulation Results in Differentiation Arrest in Acute Myeloid Leukemia
  The Journal of Clinical Investigation. Dec, 2012  |   Pubmed ID: 23160200
• MethylKit: a Comprehensive R Package for the Analysis of Genome-wide DNA Methylation Profiles
  Genome Biology. Oct, 2012  |   Pubmed ID: 23034086
• Recurrent Somatic TET2 Mutations in Normal Elderly Individuals with Clonal Hematopoiesis
  Nature Genetics. Nov, 2012  |   Pubmed ID: 23001125
• H2.0-like Homeobox Regulates Early Hematopoiesis and Promotes Acute Myeloid Leukemia
  Cancer Cell. Aug, 2012  |   Pubmed ID: 22897850
• CD25 Expression Status Improves Prognostic Risk Classification in AML Independent of Established Biomarkers: ECOG Phase 3 Trial, E1900
  Blood. Sep, 2012  |   Pubmed ID: 22855599
• IDH1(R132H) Mutation Increases Murine Haematopoietic Progenitors and Alters Epigenetics
  Nature. Aug, 2012  |   Pubmed ID: 22763442
• Base-pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia
  PLoS Genetics. 2012  |   Pubmed ID: 22737091
• Mutant DNMT3A: a Marker of Poor Prognosis in Acute Myeloid Leukemia
  Blood. Jun, 2012  |   Pubmed ID: 22490330
• Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia
  The New England Journal of Medicine. Mar, 2012  |   Pubmed ID: 22417203
• IDH Mutation Impairs Histone Demethylation and Results in a Block to Cell Differentiation
  Nature. Mar, 2012  |   Pubmed ID: 22343901
• DNA Methyltransferase 1 and DNA Methylation Patterning Contribute to Germinal Center B-cell Differentiation
  Blood. Sep, 2011  |   Pubmed ID: 21828137
• Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-renewal and Myeloid Transformation
  Cancer Cell. Jul, 2011  |   Pubmed ID: 21723200
• Aberrant DNA Hypermethylation Signature in Acute Myeloid Leukemia Directed by EVI1
  Blood. Jan, 2011  |   Pubmed ID: 20855866
• Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
  Cancer Cell. Dec, 2010  |   Pubmed ID: 21130701
• BCL6 Repression of EP300 in Human Diffuse Large B Cell Lymphoma Cells Provides a Basis for Rational Combinatorial Therapy
  The Journal of Clinical Investigation. Nov, 2010  |   Pubmed ID: 21041953
• DNMT3B7, a Truncated DNMT3B Isoform Expressed in Human Tumors, Disrupts Embryonic Development and Accelerates Lymphomagenesis
  Cancer Research. Jul, 2010  |   Pubmed ID: 20587527
• HELP (HpaII Tiny Fragment Enrichment by Ligation-mediated PCR) Assay for DNA Methylation Profiling of Primary Normal and Malignant B Lymphocytes
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 20217579
• Promoter Hypermethylation in MLL-r Infant Acute Lymphoblastic Leukemia: Biology and Therapeutic Targeting
  Blood. Jun, 2010  |   Pubmed ID: 20215641
• DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia
  Cancer Cell. Jan, 2010  |   Pubmed ID: 20060365
• MDS and Secondary AML Display Unique Patterns and Abundance of Aberrant DNA Methylation
  Blood. Oct, 2009  |   Pubmed ID: 19652201
• High-resolution Genome-wide Cytosine Methylation Profiling with Simultaneous Copy Number Analysis and Optimization for Limited Cell Numbers
  Nucleic Acids Research. Jul, 2009  |   Pubmed ID: 19386619
• Genome-wide Determination of DNA Methylation by Hpa II Tiny Fragment Enrichment by Ligation-mediated PCR (HELP) for the Study of Acute Leukemias
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19277580
• Genome-wide Epigenetic Analysis Delineates a Biologically Distinct Immature Acute Leukemia with Myeloid/T-lymphoid Features
  Blood. Mar, 2009  |   Pubmed ID: 19168792
• Kaiso Contributes to DNA Methylation-dependent Silencing of Tumor Suppressor Genes in Colon Cancer Cell Lines
  Cancer Research. Sep, 2008  |   Pubmed ID: 18794111
• An Integrative Genomic and Epigenomic Approach for the Study of Transcriptional Regulation
  PloS One. 2008  |   Pubmed ID: 18365023
• CG Dinucleotide Clustering is a Species-specific Property of the Genome
  Nucleic Acids Research. 2007  |   Pubmed ID: 17932072
• Smad1 and Smad5 Differentially Regulate Embryonic Hematopoiesis
  Blood. Dec, 2007  |   Pubmed ID: 17761518
• Comparative Isoschizomer Profiling of Cytosine Methylation: the HELP Assay
  Genome Research. Aug, 2006  |   Pubmed ID: 16809668
• Two-step Upflow Anaerobic Sludge Bed System for Sewage Treatment Under Subtropical Conditions with Posttreatment in Waste Stabilization Ponds
  Applied Biochemistry and Biotechnology. Apr-Jun, 2003  |   Pubmed ID: 12794292