Mark L. Siegal

Publications

• Extent and Context Dependence of Pleiotropy Revealed by High-throughput Single-cell Phenotyping
  PLoS Biology. 08, 2020  |   Pubmed ID: 32804946
• A Standardized Nomenclature and Atlas of the Male Terminalia of
  Fly. Mar - Dec, 2019  |   Pubmed ID: 31401934
• Feed-forward Regulation Adaptively Evolves Via Dynamics Rather Than Topology when There is Intrinsic Noise
  Nature Communications. 06, 2019  |   Pubmed ID: 31160574
• Author Correction: Testing the Key Assumption of Heritability Estimates Based on Genome-wide Genetic Relatedness
  Journal of Human Genetics. 06, 2019  |   Pubmed ID: 30940889
• Decanalizing Thinking on Genetic Canalization
  Seminars in Cell & Developmental Biology. 04, 2019  |   Pubmed ID: 29751086
• Control of Nongenetic Heterogeneity in Growth Rate and Stress Tolerance of Saccharomyces Cerevisiae by Cyclic AMP-regulated Transcription Factors
  PLoS Genetics. 11, 2018  |   Pubmed ID: 30388117
• A Sibling Method for Identifying VQTLs
  PloS One. 2018  |   Pubmed ID: 29617452
• Deep Sequencing of Natural and Experimental Populations of Reveals Biases in the Spectrum of New Mutations
  Genome Research. 12, 2017  |   Pubmed ID: 29079675
• Resolving the Complex Genetic Basis of Phenotypic Variation and Variability of Cellular Growth
  Genetics. 07, 2017  |   Pubmed ID: 28495957
• Molecular Genetics: Chaperone Protein Gets Personal
  Nature. 05, 2017  |   Pubmed ID: 28424517
• Selection Transforms the Landscape of Genetic Variation Interacting with Hsp90
  PLoS Biology. Oct, 2016  |   Pubmed ID: 27768682
• Sibling Genes As Environment: Sibling Dopamine Genotypes and Adolescent Health Support Frequency Dependent Selection
  Social Science Research. Nov, 2015  |   Pubmed ID: 26463544
• Engineering and Biology: Counsel for a Continued Relationship
  Biological Theory. Mar, 2015  |   Pubmed ID: 26085824
• A Philosophical Perspective on Evolutionary Systems Biology
  Biological Theory. Mar, 2015  |   Pubmed ID: 26085823
• Shifting Sugars and Shifting Paradigms
  PLoS Biology. Feb, 2015  |   Pubmed ID: 25688600
• Essential Gene Disruptions Reveal Complex Relationships Between Phenotypic Robustness, Pleiotropy, and Fitness
  Molecular Systems Biology. Jan, 2015  |   Pubmed ID: 25609648
• On the Nature and Evolutionary Impact of Phenotypic Robustness Mechanisms
  Annual Review of Ecology, Evolution, and Systematics. Nov, 2014  |   Pubmed ID: 26034410
• Reply to Chen and Zhang: On Interpreting Genome-wide Trends from Yeast Mutation Accumulation Data
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2014  |   Pubmed ID: 25217565
• The Genetics of Sex: Exploring Differences
  Genetics. Jun, 2014  |   Pubmed ID: 24939993
• The Genetics of Sex: Exploring Differences
  G3 (Bethesda, Md.). Jun, 2014  |   Pubmed ID: 24939183
• Precise Estimates of Mutation Rate and Spectrum in Yeast
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014  |   Pubmed ID: 24847077
• Testing the Key Assumption of Heritability Estimates Based on Genome-wide Genetic Relatedness
  Journal of Human Genetics. Jun, 2014  |   Pubmed ID: 24599117
• Histone Variant HTZ1 Shows Extensive Epistasis With, but Does Not Increase Robustness To, New Mutations
  PLoS Genetics. 2013  |   Pubmed ID: 23990806
• Genetic and Nongenetic Determinants of Cell Growth Variation Assessed by High-Throughput Microscopy
  Molecular Biology and Evolution. Sep, 2013  |   Pubmed ID: 23938868
• Heritability and the Equal Environments Assumption: Evidence from Multiple Samples of Misclassified Twins
  Behavior Genetics. Sep, 2013  |   Pubmed ID: 23903437
• Beyond Orchids and Dandelions: Testing the 5-HTT "risky" Allele for Evidence of Phenotypic Capacitance and Frequency-dependent Selection
  Biodemography and Social Biology. 2013  |   Pubmed ID: 23701535
• Crouching Variation Revealed
  Molecular Ecology. Mar, 2013  |   Pubmed ID: 23437837
• Oh, the Places They'll Go: Female Sperm Storage and Sperm Precedence in Drosophila Melanogaster
  Spermatogenesis. Jul, 2012  |   Pubmed ID: 23087839
• Polygenic Cis-regulatory Adaptation in the Evolution of Yeast Pathogenicity
  Genome Research. Oct, 2012  |   Pubmed ID: 22645260
• Pausing on the Path to Robustness
  Developmental Cell. May, 2012  |   Pubmed ID: 22595664
• Bet Hedging in Yeast by Heterogeneous, Age-correlated Expression of a Stress Protectant
  PLoS Biology. 2012  |   Pubmed ID: 22589700
• Hsp90 Depletion Goes Wild
  BMC Biology. Feb, 2012  |   Pubmed ID: 22369621
• Sperm-storage Defects and Live Birth in Drosophila Females Lacking Spermathecal Secretory Cells
  PLoS Biology. Nov, 2011  |   Pubmed ID: 22087073
• The Female-specific Doublesex Isoform Regulates Pleiotropic Transcription Factors to Pattern Genital Development in Drosophila
  Development (Cambridge, England). Mar, 2011  |   Pubmed ID: 21343364
• Correlating Gene Expression Variation with Cis-regulatory Polymorphism in Saccharomyces Cerevisiae
  Genome Biology and Evolution. 2010  |   Pubmed ID: 20829281
• Robustness: Mechanisms and Consequences
  Trends in Genetics : TIG. Sep, 2009  |   Pubmed ID: 19717203
• Reexamining MicroRNA Site Accessibility in Drosophila: a Population Genomics Study
  PloS One. May, 2009  |   Pubmed ID: 19478854
• Network Hubs Buffer Environmental Variation in Saccharomyces Cerevisiae
  PLoS Biology. Nov, 2008  |   Pubmed ID: 18986213
• Functional and Evolutionary Inference in Gene Networks: Does Topology Matter?
  Genetica. Jan, 2007  |   Pubmed ID: 16897451
• Functional Conservation and Divergence of Intersex, a Gene Required for Female Differentiation in Drosophila Melanogaster
  Development Genes and Evolution. Jan, 2005  |   Pubmed ID: 15645316