In JoVE (1)
Other Publications (1)
Articles by Marta Calatayud Arroyo in JoVE
Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface Marta Calatayud Arroyo1, Tom Van de Wiele1, Emma Hernandez-Sanabria1 1Center for Microbial Ecology and Technology (CMET), Ghent University Gut host-microbe interactions were assessed using a novel approach combining a synthetic oral community, in vitro gastrointestinal digestion, and a model of the small intestine epithelium. We present a method that can be adapted to evaluate cell invasion of pathogens and multi-species biofilms, or even to test probiotic formulations' survivability.
Other articles by Marta Calatayud Arroyo on PubMed
Modelling Upper Respiratory Tract Diseases: Getting Grips on Host-microbe Interactions in Chronic Rhinosinusitis Using in Vitro Technologies Microbiome. | Pubmed ID: 29690931 Chronic rhinosinusitis (CRS) is a chronic inflammation of the mucosa of the nose and paranasal sinuses affecting approximately 11% of the adult population in Europe. Inadequate immune responses, as well as a dysbiosis of the sinonasal microbiota, have been put forward as aetiological factors of the disease. However, despite the prevalence of this disease, there is no consensus on the aetiology and mechanisms of pathogenesis of CRS. Further research requires in vitro models mimicking the healthy and diseased host environment along with the sinonasal microbiota. This review aims to provide an overview of CRS model systems and proposes in vitro modelling strategies to conduct mechanistic research in an ecological framework on the sinonasal microbiota and its interactions with the host in health and CRS.