Martin J. Lohse Max Delbrück Center for Molecular Medicine, Berlin Biography Publications Institution JoVE Articles Martin J. Lohse has not added a biography. If you are Martin J. Lohse and would like to personalize this page please email our Author Liaison for assistance. Publications Stepwise Activation of a Class C GPCR Begins with Millisecond Dimer Rearrangement Proceedings of the National Academy of Sciences of the United States of America. 05, 2019 | Pubmed ID: 31023886 A Universal Bioluminescence Resonance Energy Transfer Sensor Design Enables High-sensitivity Screening of GPCR Activation Dynamics Communications Biology. 2018 | Pubmed ID: 30271985 The Ins and Outs of Adrenergic Signaling Journal of Molecular Medicine (Berlin, Germany). Sep, 2015 | Pubmed ID: 26199112 Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors Molecular Pharmacology. Sep, 2015 | Pubmed ID: 26184590 β-Myosin Heavy Chain Variant Val606Met Causes Very Mild Hypertrophic Cardiomyopathy in Mice, but Exacerbates HCM Phenotypes in Mice Carrying Other HCM Mutations Circulation Research. Jul, 2014 | Pubmed ID: 24829265 Role of Membrane Microdomains in Compartmentation of CAMP Signaling PloS One. 2014 | Pubmed ID: 24752595 Constitutive Activation of PKA Catalytic Subunit in Adrenal Cushing's Syndrome The New England Journal of Medicine. Mar, 2014 | Pubmed ID: 24571724 Kinetics and Mechanism of G Protein-coupled Receptor Activation Current Opinion in Cell Biology. Apr, 2014 | Pubmed ID: 24530699 G Protein-coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives Pharmacological Reviews. Apr, 2014 | Pubmed ID: 24515647 Crosstalk Between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium Cell. Jan, 2014 | Pubmed ID: 24485454 Arrestin Interactions with G Protein-coupled Receptors Handbook of Experimental Pharmacology. 2014 | Pubmed ID: 24292823 Gene Amplification and Functional Diversification of Melanocortin 4 Receptor at an Extremely Polymorphic Locus Controlling Sexual Maturation in the Platyfish Genetics. Dec, 2013 | Pubmed ID: 24077304 Time-resolved Fluorescence Ligand Binding for G Protein-coupled Receptors Nature Protocols. 2013 | Pubmed ID: 23764938 Interference with ERK(Thr188) Phosphorylation Impairs Pathological but Not Physiological Cardiac Hypertrophy Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23589880 Cell Biology: Receptor Signals Come in Waves Nature. Mar, 2013 | Pubmed ID: 23515157 Single-molecule Analysis of Fluorescently Labeled G-protein-coupled Receptors Reveals Complexes with Distinct Dynamics and Organization Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23267088 Administration of the Cyclic Peptide COR-1 in Humans (phase I Study): Ex Vivo Measurements of Anti-β1-adrenergic Receptor Antibody Neutralization and of Immune Parameters European Journal of Heart Failure. Nov, 2012 | Pubmed ID: 22968742 Sequential Inter- and Intrasubunit Rearrangements During Activation of Dimeric Metabotropic Glutamate Receptor 1 Science Signaling. Aug, 2012 | Pubmed ID: 22894836 β-Adrenergic Receptor Stimulation Causes Cardiac Hypertrophy Via a Gβγ/Erk-dependent Pathway Cardiovascular Research. Nov, 2012 | Pubmed ID: 22843704 Detection of Anti-β1-AR Autoantibodies in Heart Failure by a Cell-based Competition ELISA Circulation Research. Aug, 2012 | Pubmed ID: 22811559 Raf Kinase Inhibitor Protein (RKIP) Dimer Formation Controls Its Target Switch from Raf1 to G Protein-coupled Receptor Kinase (GRK) 2 The Journal of Biological Chemistry. Jul, 2012 | Pubmed ID: 22610096 Comparison of the Activation Kinetics of the M3 Acetylcholine Receptor and a Constitutively Active Mutant Receptor in Living Cells Molecular Pharmacology. Aug, 2012 | Pubmed ID: 22564786 The Guanine Nucleotide Exchange Factor Vav2 is a Negative Regulator of Parathyroid Hormone Receptor/Gq Signaling Molecular Pharmacology. Aug, 2012 | Pubmed ID: 22554804 Fluorescence/bioluminescence Resonance Energy Transfer Techniques to Study G-protein-coupled Receptor Activation and Signaling Pharmacological Reviews. Apr, 2012 | Pubmed ID: 22407612 Nonequilibrium Activation of a G-protein-coupled Receptor Molecular Pharmacology. Jun, 2012 | Pubmed ID: 22379120 Persistent CAMP Signaling by Internalized TSH Receptors Occurs in Thyroid but Not in HEK293 Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2012 | Pubmed ID: 22291442 Developing Chemical Genetic Approaches to Explore G Protein-coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL) Molecular Pharmacology. Dec, 2011 | Pubmed ID: 21880827 FRET Measurements of Intracellular CAMP Concentrations and CAMP Analog Permeability in Intact Cells Nature Protocols. Apr, 2011 | Pubmed ID: 21412271 Distinct Pharmacological Properties of Morphine Metabolites at G(i)-protein and β-arrestin Signaling Pathways Activated by the Human μ-opioid Receptor Biochemical Pharmacology. May, 2011 | Pubmed ID: 21396918 Rotational Diffusion of the α(2a) Adrenergic Receptor Revealed by FlAsH Labeling in Living Cells Biophysical Journal. Feb, 2011 | Pubmed ID: 21320460 Sensing G Protein-coupled Receptor Activation Neuropharmacology. Jan, 2011 | Pubmed ID: 20727363 FRET-based Sensors for the Human M1-, M3-, and M5-acetylcholine Receptors Bioorganic & Medicinal Chemistry. Feb, 2011 | Pubmed ID: 20716489 Fluorescent Labeling of Tetracysteine-tagged Proteins in Intact Cells Nature Protocols. Sep, 2010 | Pubmed ID: 20885379 Determination of Onset of Sexual Maturation and Mating Behavior by Melanocortin Receptor 4 Polymorphisms Current Biology : CB. Oct, 2010 | Pubmed ID: 20869245 Differential Signaling of the Endogenous Agonists at the Beta2-adrenergic Receptor The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20837485 Formation of a Ternary Complex Among NHERF1, Beta-arrestin, and Parathyroid Hormone Receptor The Journal of Biological Chemistry. Sep, 2010 | Pubmed ID: 20656684 Microscopy: GPCR Dimers Moving Closer Nature Chemical Biology. Aug, 2010 | Pubmed ID: 20644543 Real-time Monitoring of Somatostatin Receptor-cAMP Signaling in Live Pituitary Endocrinology. Sep, 2010 | Pubmed ID: 20610560 GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base Bioinformatics (Oxford, England). Jul, 2010 | Pubmed ID: 20501551 Cardiac Beta1-adrenoceptor Autoantibodies in Human Heart Disease: Rationale and Design of the Etiology, Titre-Course, and Survival (ETiCS) Study European Journal of Heart Failure. Jul, 2010 | Pubmed ID: 20494925 Site-specific, Orthogonal Labeling of Proteins in Intact Cells with Two Small Biarsenical Fluorophores Bioconjugate Chemistry. May, 2010 | Pubmed ID: 20429545 Polarization of Migrating Monocytic Cells is Independent of PI 3-kinase Activity PloS One. 2010 | Pubmed ID: 20419163 Targeting Receptor Antibodies in Immune Cardiomyopathy Seminars in Thrombosis and Hemostasis. Mar, 2010 | Pubmed ID: 20414837 Imaging of Persistent CAMP Signaling by Internalized G Protein-coupled Receptors Journal of Molecular Endocrinology. Jul, 2010 | Pubmed ID: 20378719 Signaling by Internalized G-protein-coupled Receptors Trends in Pharmacological Sciences. May, 2010 | Pubmed ID: 20303186 Beta2-adrenergic Receptor Redistribution in Heart Failure Changes CAMP Compartmentation Science (New York, N.Y.). Mar, 2010 | Pubmed ID: 20185685 Ca2+ Cycling and New Therapeutic Approaches for Heart Failure Circulation. Feb, 2010 | Pubmed ID: 20124124 A Fluorescence Resonance Energy Transfer-based M2 Muscarinic Receptor Sensor Reveals Rapid Kinetics of Allosteric Modulation The Journal of Biological Chemistry. Mar, 2010 | Pubmed ID: 20083608 Agonist-regulated Cleavage of the Extracellular Domain of Parathyroid Hormone Receptor Type 1 The Journal of Biological Chemistry. Mar, 2010 | Pubmed ID: 20080964 Distinct Pools of CAMP Centre on Different Isoforms of Adenylyl Cyclase in Pituitary-derived GH3B6 Cells Journal of Cell Science. Jan, 2010 | Pubmed ID: 20016070 Dimerization in GPCR Mobility and Signaling Current Opinion in Pharmacology. Feb, 2010 | Pubmed ID: 19910252 Gq-mediated Ca2+ Signals Inhibit Adenylyl Cyclases 5/6 in Vascular Smooth Muscle Cells American Journal of Physiology. Cell Physiology. Feb, 2010 | Pubmed ID: 19889965 Phosducin Influences Sympathetic Activity and Prevents Stress-induced Hypertension in Humans and Mice The Journal of Clinical Investigation. Dec, 2009 | Pubmed ID: 19959875 Beta-Arrestin-2 Interaction and Internalization of the Human P2Y1 Receptor Are Dependent on C-terminal Phosphorylation Sites Molecular Pharmacology. Dec, 2009 | Pubmed ID: 19741005 Persistent CAMP-signals Triggered by Internalized G-protein-coupled Receptors PLoS Biology. Aug, 2009 | Pubmed ID: 19688034 A Technique for Monitoring Multiple Signals with a Combination of Prism-based Total Internal Reflection Fluorescence Microscopy and Epifluorescence Microscopy Pflügers Archiv : European Journal of Physiology. Nov, 2009 | Pubmed ID: 19680684 Cardiac Hypertrophy: Targeting Raf/MEK/ERK1/2-signaling The International Journal of Biochemistry & Cell Biology. Dec, 2009 | Pubmed ID: 19666137 Sweet Taste Receptor Expressed in Pancreatic Beta-cells Activates the Calcium and Cyclic AMP Signaling Systems and Stimulates Insulin Secretion PloS One. 2009 | Pubmed ID: 19352508 Analysis of Receptor Oligomerization by FRAP Microscopy Nature Methods. Mar, 2009 | Pubmed ID: 19234451 Building a New Conceptual Framework for Receptor Heteromers Nature Chemical Biology. Mar, 2009 | Pubmed ID: 19219011 GPCR and G Proteins: Drug Efficacy and Activation in Live Cells Molecular Endocrinology (Baltimore, Md.). May, 2009 | Pubmed ID: 19196832 Alterations of Phospholamban Function Can Exhibit Cardiotoxic Effects Independent of Excessive Sarcoplasmic Reticulum Ca2+-ATPase Inhibition Circulation. Jan, 2009 | Pubmed ID: 19139388 Critical Role of Transcription Factor Cyclic AMP Response Element Modulator in Beta1-adrenoceptor-mediated Cardiac Dysfunction Circulation. Jan, 2009 | Pubmed ID: 19103994 Novel Techniques for Real-time Monitoring of CGMP in Living Cells Handbook of Experimental Pharmacology. 2009 | Pubmed ID: 19089332 A New Type of ERK1/2 Autophosphorylation Causes Cardiac Hypertrophy Nature Medicine. Jan, 2009 | Pubmed ID: 19060905 Dual Role of the Beta2-adrenergic Receptor C Terminus for the Binding of Beta-arrestin and Receptor Internalization The Journal of Biological Chemistry. Nov, 2008 | Pubmed ID: 18801735 Pathological Autoantibodies in Cardiomyopathy Autoimmunity. Sep, 2008 | Pubmed ID: 18781471 Blocking Them All: Beta-arrestins Inhibit Cellular Signaling Molecular Cell. Sep, 2008 | Pubmed ID: 18775321 Agonist-selective, Receptor-specific Interaction of Human P2Y Receptors with Beta-arrestin-1 and -2 The Journal of Biological Chemistry. Nov, 2008 | Pubmed ID: 18703513 Cytoplasmic CAMP Concentrations in Intact Cardiac Myocytes American Journal of Physiology. Cell Physiology. Aug, 2008 | Pubmed ID: 18550706 Integrin Alpha E(CD103)beta 7 Influences Cellular Shape and Motility in a Ligand-dependent Fashion Blood. Aug, 2008 | Pubmed ID: 18492951 Real-time Monitoring of Phosphodiesterase Inhibition in Intact Cells Cellular Signalling. Aug, 2008 | Pubmed ID: 18467075 Widespread Receptivity to Neuropeptide PDF Throughout the Neuronal Circadian Clock Network of Drosophila Revealed by Real-time Cyclic AMP Imaging Neuron. Apr, 2008 | Pubmed ID: 18439407 Optical Techniques to Analyze Real-time Activation and Signaling of G-protein-coupled Receptors Trends in Pharmacological Sciences. Mar, 2008 | Pubmed ID: 18262662 An RNA Molecule That Specifically Inhibits G-protein-coupled Receptor Kinase 2 in Vitro RNA (New York, N.Y.). Mar, 2008 | Pubmed ID: 18230760 Kinetics of G-protein-coupled Receptor Signals in Intact Cells British Journal of Pharmacology. Mar, 2008 | Pubmed ID: 18193071 Conformational Cross-talk Between Alpha2A-adrenergic and Mu-opioid Receptors Controls Cell Signaling Nature Chemical Biology. Feb, 2008 | Pubmed ID: 18193048 Activation of AP-1 Contributes to the Beta-adrenoceptor-mediated Myocardial Induction of Interleukin-6 Molecular Medicine (Cambridge, Mass.). Nov-Dec, 2007 | Pubmed ID: 17948064 Monitoring Receptor Signaling by Intramolecular FRET Current Opinion in Pharmacology. Oct, 2007 | Pubmed ID: 17919975 Kinetic Analysis of G Protein-coupled Receptor Signaling Using Fluorescence Resonance Energy Transfer in Living Cells Advances in Protein Chemistry. 2007 | Pubmed ID: 17854658 A Novel Fluorescence Method for the Rapid Detection of Functional Beta1-adrenergic Receptor Autoantibodies in Heart Failure Journal of the American College of Cardiology. Jul, 2007 | Pubmed ID: 17662395 Live Cell Monitoring of Mu-opioid Receptor-mediated G-protein Activation Reveals Strong Biological Activity of Close Morphine Biosynthetic Precursors The Journal of Biological Chemistry. Sep, 2007 | Pubmed ID: 17616524 Requirements and Ontology for a G Protein-coupled Receptor Oligomerization Knowledge Base BMC Bioinformatics. 2007 | Pubmed ID: 17537266 International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-coupled Receptor Heteromultimers Pharmacological Reviews. Mar, 2007 | Pubmed ID: 17329545 A Role for Caspase-1 in Heart Failure Circulation Research. Mar, 2007 | Pubmed ID: 17303764 CAMP Microdomains and L-type Ca2+ Channel Regulation in Guinea-pig Ventricular Myocytes The Journal of Physiology. May, 2007 | Pubmed ID: 17289786 Direct Inhibition of Cardiac Hyperpolarization-activated Cyclic Nucleotide-gated Pacemaker Channels by Clonidine Circulation. Feb, 2007 | Pubmed ID: 17261653 Real-time Optical Recording of Beta1-adrenergic Receptor Activation Reveals Supersensitivity of the Arg389 Variant to Carvedilol The Journal of Clinical Investigation. Jan, 2007 | Pubmed ID: 17200720 Interstitial Remodeling in Beta1-adrenergic Receptor Transgenic Mice Basic Research in Cardiology. Mar, 2007 | Pubmed ID: 17122889 G Protein-coupled Receptors: Too Many Dimers? Nature Methods. Dec, 2006 | Pubmed ID: 17117152 Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-reaching Beta1-adrenergic but Locally Confined Beta2-adrenergic Receptor-mediated Signaling Circulation Research. Nov, 2006 | Pubmed ID: 17038640 Stimulating Autoantibodies Directed Against the Cardiac Beta1-adrenergic Receptor Predict Increased Mortality in Idiopathic Cardiomyopathy American Heart Journal. Oct, 2006 | Pubmed ID: 16996841 Simultaneous Optical Measurements of Cytosolic Ca2+ and CAMP in Single Cells Science's STKE : Signal Transduction Knowledge Environment. Sep, 2006 | Pubmed ID: 16985238 Cardiac Myosin Missense Mutations Cause Dilated Cardiomyopathy in Mouse Models and Depress Molecular Motor Function Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16983074 Gs Activation is Time-limiting in Initiating Receptor-mediated Signaling The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 16963443 Beta 1-adrenergic Receptor-directed Autoimmunity As a Cause of Dilated Cardiomyopathy in Rats International Journal of Cardiology. Sep, 2006 | Pubmed ID: 16872696 Molecular Basis of Partial Agonism at the Neurotransmitter Alpha2A-adrenergic Receptor and Gi-protein Heterotrimer The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16787921 Monitoring of CAMP Synthesis and Degradation in Living Cells Physiology (Bethesda, Md.). Apr, 2006 | Pubmed ID: 16565474 SUMO-1 Controls the Protein Stability and the Biological Function of Phosducin The Journal of Biological Chemistry. Mar, 2006 | Pubmed ID: 16421094 Beta(1)-Adrenergic Receptor Function, Autoimmunity, and Pathogenesis of Dilated Cardiomyopathy Trends in Cardiovascular Medicine. Jan, 2006 | Pubmed ID: 16387626 Fluorescent Sensors for Rapid Monitoring of Intracellular CGMP Nature Methods. Jan, 2006 | Pubmed ID: 16369548 Molecular Basis of Inverse Agonism in a G Protein-coupled Receptor Nature Chemical Biology. Jun, 2005 | Pubmed ID: 16407989 Dynamics of Receptor/G Protein Coupling in Living Cells The EMBO Journal. Dec, 2005 | Pubmed ID: 16292347 Turn-on Switch in Parathyroid Hormone Receptor by a Two-step Parathyroid Hormone Binding Mechanism Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16236727 Peptide Inhibitors of G Protein-coupled Receptor Kinases Biochemical Pharmacology. Oct, 2005 | Pubmed ID: 16102734 The Transcriptional Repressor Nab1 is a Specific Regulator of Pathological Cardiac Hypertrophy Nature Medicine. Aug, 2005 | Pubmed ID: 16025126 Interplay of Ca2+ and CAMP Signaling in the Insulin-secreting MIN6 Beta-cell Line The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 15987680 G Protein Activation Without Subunit Dissociation Depends on a G{alpha}(i)-specific Region The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15866880 A FlAsH-based FRET Approach to Determine G Protein-coupled Receptor Activation in Living Cells Nature Methods. Mar, 2005 | Pubmed ID: 15782185 Phosducin-like Protein Regulates G-protein Betagamma Folding by Interaction with Tailless Complex Polypeptide-1alpha: Dephosphorylation or Splicing of PhLP Turns the Switch Toward Regulation of Gbetagamma Folding The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15745879 Self-limitation of Intravenous Tocolysis with Beta2-adrenergic Agonists is Mediated Through Receptor G Protein Uncoupling The Journal of Clinical Endocrinology and Metabolism. May, 2005 | Pubmed ID: 15728216 Beta-arrestin Binding to the Beta2-adrenergic Receptor Requires Both Receptor Phosphorylation and Receptor Activation The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15634674 Real-time Monitoring of the PDE2 Activity of Live Cells: Hormone-stimulated CAMP Hydrolysis is Faster Than Hormone-stimulated CAMP Synthesis The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15557342 Kinetics of G-protein-coupled Receptor Signalling and Desensitization Biochemical Society Transactions. Dec, 2004 | Pubmed ID: 15506955 Novel Single Chain CAMP Sensors for Receptor-induced Signal Propagation The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15231839 Fluorescence Resonance Energy Transfer-based Analysis of CAMP Dynamics in Live Neonatal Rat Cardiac Myocytes Reveals Distinct Functions of Compartmentalized Phosphodiesterases Circulation Research. Jul, 2004 | Pubmed ID: 15178638 Direct Evidence for a Beta 1-adrenergic Receptor-directed Autoimmune Attack As a Cause of Idiopathic Dilated Cardiomyopathy The Journal of Clinical Investigation. May, 2004 | Pubmed ID: 15146239 Beta-adrenoceptor Polymorphisms and Heart Failure Trends in Molecular Medicine. Feb, 2004 | Pubmed ID: 15106619 Calcium Channel Function and Regulation in Beta 1- and Beta 2-adrenoceptor Transgenic Mice Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2004 | Pubmed ID: 15083268 Transgenic Triadin 1 Overexpression Alters SR Ca2+ Handling and Leads to a Blunted Contractile Response to Beta-adrenergic Agonists Cardiovascular Research. Apr, 2004 | Pubmed ID: 15023559 Altered Calcium Handling is Critically Involved in the Cardiotoxic Effects of Chronic Beta-adrenergic Stimulation Circulation. Mar, 2004 | Pubmed ID: 14967726 Molecular Mechanisms of Receptor Activation: Real-time Analysis by Fluorescence Resonance Energy Transfer Autonomic & Autacoid Pharmacology. Aug, 2003 | Pubmed ID: 15134067 Gi Protein Activation in Intact Cells Involves Subunit Rearrangement Rather Than Dissociation Proceedings of the National Academy of Sciences of the United States of America. Dec, 2003 | Pubmed ID: 14673086 Protein Kinase C Switches the Raf Kinase Inhibitor from Raf-1 to GRK-2 Nature. Dec, 2003 | Pubmed ID: 14654844 Common Genomic Response in Different Mouse Models of Beta-adrenergic-induced Cardiomyopathy Circulation. Dec, 2003 | Pubmed ID: 14623810 What is the Role of Beta-adrenergic Signaling in Heart Failure? Circulation Research. Nov, 2003 | Pubmed ID: 14615493 Direct Optical Recording of Intrinsic Efficacy at a G Protein-coupled Receptor Life Sciences. Dec, 2003 | Pubmed ID: 14607268 Disruption of Cardiac Ena-VASP Protein Localization in Intercalated Disks Causes Dilated Cardiomyopathy American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2003 | Pubmed ID: 12933343 Partial Agonist Activity of Bucindolol is Dependent on the Activation State of the Human Beta1-adrenergic Receptor Circulation. Jul, 2003 | Pubmed ID: 12847069 Measurement of the Millisecond Activation Switch of G Protein-coupled Receptors in Living Cells Nature Biotechnology. Jul, 2003 | Pubmed ID: 12808462 Differential Control of Adrenal and Sympathetic Catecholamine Release by Alpha 2-adrenoceptor Subtypes Molecular Endocrinology (Baltimore, Md.). Aug, 2003 | Pubmed ID: 12764077 Alterations in the Myocardial Creatine Kinase System Precede the Development of Contractile Dysfunction in Beta(1)-adrenergic Receptor Transgenic Mice Journal of Molecular and Cellular Cardiology. Apr, 2003 | Pubmed ID: 12689818 Peptide G Protein Agonists from a Phage Display Library Biochemical Pharmacology. Mar, 2003 | Pubmed ID: 12623127 The Amino-terminal Domain of G-protein-coupled Receptor Kinase 2 is a Regulatory Gbeta Gamma Binding Site The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12486133 Regulation of Phosducin-like Protein by Casein Kinase 2 and N-terminal Splicing The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12466282 Regulation of the Inward Rectifying Properties of G-protein-activated Inwardly Rectifying K+ (GIRK) Channels by Gbeta Gamma Subunits The Journal of Biological Chemistry. Jan, 2003 | Pubmed ID: 12403784 Mutation of Asn293 to Asp in Transmembrane Helix VI Abolishes Agonist-induced but Not Constitutive Activity of the Beta(2)-adrenergic Receptor Molecular Pharmacology. Dec, 2002 | Pubmed ID: 12435811 Feedback Inhibition of Catecholamine Release by Two Different Alpha2-adrenoceptor Subtypes Prevents Progression of Heart Failure Circulation. Nov, 2002 | Pubmed ID: 12417548 Dual Regulation of the Parathyroid Hormone (PTH)/PTH-related Peptide Receptor Signaling by Protein Kinase C and Beta-arrestins Endocrinology. Oct, 2002 | Pubmed ID: 12239097 Modulation of a Brain Voltage-gated K+ Channel by Syntaxin 1A Requires the Physical Interaction of Gbetagamma with the Channel The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12114518 Magnesium and the Parathyroid Current Opinion in Nephrology and Hypertension. Jul, 2002 | Pubmed ID: 12105390 Placental Alpha(2)-adrenoceptors Control Vascular Development at the Interface Between Mother and Embryo Nature Genetics. Jul, 2002 | Pubmed ID: 12068299 Inhibition of Na(+)-H(+) Exchange Prevents Hypertrophy, Fibrosis, and Heart Failure in Beta(1)-adrenergic Receptor Transgenic Mice Circulation Research. Apr, 2002 | Pubmed ID: 11964375 Internalization Determinants of the Parathyroid Hormone Receptor Differentially Regulate Beta-arrestin/receptor Association The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11726668 New Directions in Pharmacology Lancet (London, England). Dec, 1999 | Pubmed ID: 10691466 Dual-Color Fluorescence Cross-Correlation Spectroscopy to Study Protein-Protein Interaction and Protein Dynamics in Live Cells Katherina Hemmen*1, Susobhan Choudhury*1, Mike Friedrich1, Johannes Balkenhol1, Felix Knote1, Martin J. Lohse2, Katrin G. Heinze1 1Rudolf Virchow Center for Integrative and Translation Bioimaging, Julius-Maximilian University Wuerzburg, 2Max Delbrück Center for Molecular Medicine, Berlin JoVE 62954 Biochemistry High-resolution Spatiotemporal Analysis of Receptor Dynamics by Single-molecule Fluorescence Microscopy Titiwat Sungkaworn1, Finn Rieken1, Martin J. Lohse1, Davide Calebiro1 1Institute of Pharmacology and Toxicology and Bio-Imaging Center/Rudolf Virchow Center, DFG-Research Center for Experimental Biomedicine, University of Würzburg, Germany JoVE 51784 Bioengineering
Dual-Color Fluorescence Cross-Correlation Spectroscopy to Study Protein-Protein Interaction and Protein Dynamics in Live Cells Katherina Hemmen*1, Susobhan Choudhury*1, Mike Friedrich1, Johannes Balkenhol1, Felix Knote1, Martin J. Lohse2, Katrin G. Heinze1 1Rudolf Virchow Center for Integrative and Translation Bioimaging, Julius-Maximilian University Wuerzburg, 2Max Delbrück Center for Molecular Medicine, Berlin JoVE 62954 Biochemistry
High-resolution Spatiotemporal Analysis of Receptor Dynamics by Single-molecule Fluorescence Microscopy Titiwat Sungkaworn1, Finn Rieken1, Martin J. Lohse1, Davide Calebiro1 1Institute of Pharmacology and Toxicology and Bio-Imaging Center/Rudolf Virchow Center, DFG-Research Center for Experimental Biomedicine, University of Würzburg, Germany JoVE 51784 Bioengineering
