Masahito Ikawa

Publications

• Trim41 is Required to Regulate Chromosome Axis Protein Dynamics and Meiosis in Male Mice
  PLoS Genetics. 06, 2022  |   Pubmed ID: 35648791
• TULP2 Deletion Mice Exhibit Abnormal Outer Dense Fiber Structure and Male Infertility
  Reproductive Medicine and Biology. Jan-Dec, 2022  |   Pubmed ID: 35619658
• IRGC1, a Testis-enriched Immunity Related GTPase, is Important for Fibrous Sheath Integrity and Sperm Motility in Mice
  Developmental Biology. 08, 2022  |   Pubmed ID: 35618043
• Proteolysis in Reproduction: Lessons From Gene-Modified Organism Studies
  Frontiers in Endocrinology. 2022  |   Pubmed ID: 35600599
• Sperm Membrane Proteins DCST1 and DCST2 Are Required for Sperm-egg Interaction in Mice and Fish
  Communications Biology. 04, 2022  |   Pubmed ID: 35393517
• Kastor and Polluks Polypeptides Encoded by a Single Gene Locus Cooperatively Regulate VDAC and Spermatogenesis
  Nature Communications. 02, 2022  |   Pubmed ID: 35228556
• The Motor Domain of Testis-enriched Kinesin KIF9 is Essential for Its Localization in the Mouse Flagellum
  Experimental Animals. Feb, 2022  |   Pubmed ID: 34526446
• CRISPR/Cas9-mediated Genome Editing Reveals 12 Testis-enriched Genes Dispensable for Male Fertility in Mice
  Asian Journal of Andrology. May-Jun, 2022  |   Pubmed ID: 34290169
• Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats
  Frontiers in Cell and Developmental Biology. 2021  |   Pubmed ID: 35096839
• FAM71F1 Binds to RAB2A and RAB2B and is Essential for Acrosome Formation and Male Fertility in Mice
  Development (Cambridge, England). 11, 2021  |   Pubmed ID: 34714330
• LRRC23 is a Conserved Component of the Radial Spoke That is Necessary for Sperm Motility and Male Fertility in Mice
  Journal of Cell Science. 10, 2021  |   Pubmed ID: 34585727
• The Conserved Fertility Factor SPACA4/Bouncer Has Divergent Modes of Action in Vertebrate Fertilization
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2021  |   Pubmed ID: 34556579
• SPATA33 Localizes Calcineurin to the Mitochondria and Regulates Sperm Motility in Mice
  Proceedings of the National Academy of Sciences of the United States of America. 08, 2021  |   Pubmed ID: 34446558
• A Sublethal ATP11A Mutation Associated with Neurological Deterioration Causes Aberrant Phosphatidylcholine Flipping in Plasma Membranes
  The Journal of Clinical Investigation. 09, 2021  |   Pubmed ID: 34403372
• Uterine Epithelial LIF Receptors Contribute to Implantation Chamber Formation in Blastocyst Attachment
  Endocrinology. 11, 2021  |   Pubmed ID: 34402888
• Rubicon Prevents Autophagic Degradation of GATA4 to Promote Sertoli Cell Function
  PLoS Genetics. 08, 2021  |   Pubmed ID: 34351902
• Precise CAG Repeat Contraction in a Huntington's Disease Mouse Model is Enabled by Gene Editing with SpCas9-NG
  Communications Biology. 06, 2021  |   Pubmed ID: 34163001
• KCTD19 and Its Associated Protein ZFP541 Are Independently Essential for Meiosis in Male Mice
  PLoS Genetics. 05, 2021  |   Pubmed ID: 33961623
• ARMC12 Regulates Spatiotemporal Mitochondrial Dynamics During Spermiogenesis and is Required for Male Fertility
  Proceedings of the National Academy of Sciences of the United States of America. 02, 2021  |   Pubmed ID: 33536340
• Protocol for Isolation of Spermatids from Mouse Testes
  STAR Protocols. 03, 2021  |   Pubmed ID: 33490974
• Astrocytic CAMP Modulates Memory Via Synaptic Plasticity
  Proceedings of the National Academy of Sciences of the United States of America. 01, 2021  |   Pubmed ID: 33452135
• CRISPR/CAS9-mediated Amino Acid Substitution Reveals Phosphorylation Residues of RSPH6A Are Not Essential for Male Fertility in Mice†
  Biology of Reproduction. 10, 2020  |   Pubmed ID: 32901808
• PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange During Spermiogenesis
  Cell Reports. 07, 2020  |   Pubmed ID: 32726616
• RNA-binding Protein Ptbp1 Regulates Alternative Splicing and Transcriptome in Spermatogonia and Maintains Spermatogenesis in Concert with Nanos3
  The Journal of Reproduction and Development. Oct, 2020  |   Pubmed ID: 32624547
• Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility
  American Journal of Human Genetics. 08, 2020  |   Pubmed ID: 32619401
• Knockout of Family with Sequence Similarity 170 Member A (Fam170a) Causes Male Subfertility, While Fam170b is Dispensable in Mice†
  Biology of Reproduction. 08, 2020  |   Pubmed ID: 32588889
• CRISPR/Cas9-based Genome Editing in Mice Uncovers 13 Testis- or Epididymis-enriched Genes Individually Dispensable for Male Reproduction†
  Biology of Reproduction. 08, 2020  |   Pubmed ID: 32588039
• CRISPR/Cas9-mediated Genome-edited Mice Reveal 10 Testis-enriched Genes Are Dispensable for Male Fecundity
  Biology of Reproduction. 08, 2020  |   Pubmed ID: 32561905
• Analysis of the Sperm Flagellar Axoneme Using Gene-modified Mice
  Experimental Animals. 11, 2020  |   Pubmed ID: 32554934
• Tmprss12 is Required for Sperm Motility and Uterotubal Junction Migration in Mice†
  Biology of Reproduction. 08, 2020  |   Pubmed ID: 32529245
• NELL2-mediated Lumicrine Signaling Through OVCH2 is Required for Male Fertility
  Science (New York, N.Y.). 06, 2020  |   Pubmed ID: 32499443
• CIB4 is Essential for the Haploid Phase of Spermatogenesis in Mice†
  Biology of Reproduction. 08, 2020  |   Pubmed ID: 32430498
• Sperm Proteins SOF1, TMEM95, and SPACA6 Are Required for Sperm-oocyte Fusion in Mice
  Proceedings of the National Academy of Sciences of the United States of America. 05, 2020  |   Pubmed ID: 32393636
• Knockout of Serine-rich Single-pass Membrane Protein 1 (Ssmem1) Causes Globozoospermia and Sterility in Male Mice†
  Biology of Reproduction. 08, 2020  |   Pubmed ID: 32301969
• Prss55 but Not Prss51 is Required for Male Fertility in Mice†
  Biology of Reproduction. 08, 2020  |   Pubmed ID: 32301961
• Spermatozoa Lacking Fertilization Influencing Membrane Protein (FIMP) Fail to Fuse with Oocytes in Mice
  Proceedings of the National Academy of Sciences of the United States of America. 04, 2020  |   Pubmed ID: 32295885
• Structural Insights into Tetraspanin CD9 Function
  Nature Communications. 03, 2020  |   Pubmed ID: 32231207
• CRISPR/Cas9-Mediated Genome Editing Reveals Family Genes Are Dispensable for Female Fertility in Mice
  Cells. 03, 2020  |   Pubmed ID: 32231122
• Testis-enriched Kinesin KIF9 is Important for Progressive Motility in Mouse Spermatozoa
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 04, 2020  |   Pubmed ID: 32072696
• Nexin-Dynein Regulatory Complex Component DRC7 but Not FBXL13 is Required for Sperm Flagellum Formation and Male Fertility in Mice
  PLoS Genetics. 01, 2020  |   Pubmed ID: 31961863
• Tesmin, Metallothionein-Like 5, is Required for Spermatogenesis in Mice†
  Biology of Reproduction. 04, 2020  |   Pubmed ID: 31916570
• Genetic Mutation of Frem3 Does Not CauseFraser Syndrome in Mice
  Experimental Animals. Jan, 2020  |   Pubmed ID: 31554749
• The Testis-specific Serine Proteases PRSS44, PRSS46, and PRSS54 Are Dispensable for Male Mouse Fertility†
  Biology of Reproduction. 02, 2020  |   Pubmed ID: 31403672
• Male Mice, Caged in the International Space Station for 35 Days, Sire Healthy Offspring
  Scientific Reports. 09, 2019  |   Pubmed ID: 31551430
• Identification of Multiple Male Reproductive Tract-specific Proteins That Regulate Sperm Migration Through the Oviduct in Mice
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2019  |   Pubmed ID: 31455729
• Physiological Function of Seminal Vesicle Secretions on Male Fecundity
  Reproductive Medicine and Biology. Jul, 2019  |   Pubmed ID: 31312102
• Erratum: Publisher Correction: Calaxin is Required for Cilia-driven Determination of Vertebrate Laterality
  Communications Biology. 2019  |   Pubmed ID: 31286071
• Calaxin is Required for Cilia-driven Determination of Vertebrate Laterality
  Communications Biology. 2019  |   Pubmed ID: 31240264
• CRISPR/Cas9-mediated Genome Editing Reveals 30 Testis-enriched Genes Dispensable for Male Fertility in Mice†
  Biology of Reproduction. 08, 2019  |   Pubmed ID: 31201419
• Lvrn Expression is Not Critical for Mouse Placentation
  The Journal of Reproduction and Development. Jun, 2019  |   Pubmed ID: 30745494
• Glycerol Kinase 2 is Essential for Proper Arrangement of Crescent-like Mitochondria to Form the Mitochondrial Sheath During Mouse Spermatogenesis
  The Journal of Reproduction and Development. Apr, 2019  |   Pubmed ID: 30662012
• An Azoospermic Factor Gene, Ddx3y and Its Paralog, Ddx3x Are Dispensable in Germ Cells for Male Fertility
  The Journal of Reproduction and Development. Apr, 2019  |   Pubmed ID: 30613052
• Seminal Vesicle Secretory Protein 7, PATE4, is Not Required for Sperm Function but for Copulatory Plug Formation to Ensure Fecundity†
  Biology of Reproduction. 04, 2019  |   Pubmed ID: 30452524
• PTBP1 Contributes to Spermatogenesis Through Regulation of Proliferation in Spermatogonia
  The Journal of Reproduction and Development. Feb, 2019  |   Pubmed ID: 30416150
• Chimeric Analysis with Newly Established EGFP/DsRed2-tagged ES Cells Identify HYDIN As Essential for Spermiogenesis in Mice
  Experimental Animals. Feb, 2019  |   Pubmed ID: 30089752
• Co-expression of Sperm Membrane Proteins CMTM2A and CMTM2B is Essential for ADAM3 Localization and Male Fertility in Mice
  Journal of Cell Science. 10, 2018  |   Pubmed ID: 30209135
• RSPH6A is Required for Sperm Flagellum Formation and Male Fertility in Mice
  Journal of Cell Science. 10, 2018  |   Pubmed ID: 30185526
• New Insights into the Molecular Events of Mammalian Fertilization
  Trends in Biochemical Sciences. 10, 2018  |   Pubmed ID: 30170889
• Engineered CRISPR-Cas9 Nuclease with Expanded Targeting Space
  Science (New York, N.Y.). 09, 2018  |   Pubmed ID: 30166441
• Sperm-borne Phospholipase C Zeta-1 Ensures Monospermic Fertilization in Mice
  Scientific Reports. 01, 2018  |   Pubmed ID: 29358633
• Factors Controlling Sperm Migration Through the Oviduct Revealed by Gene-modified Mouse Models
  Experimental Animals. May, 2018  |   Pubmed ID: 29353867
• Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models
  International Journal of Molecular Sciences. Oct, 2017  |   Pubmed ID: 29065458
• Placenta-specific Gene Manipulation Using Lentiviral Vector and Its Application
  Placenta. Nov, 2017  |   Pubmed ID: 28988726
• Genome Editing in Mouse Zygotes and Embryonic Stem Cells by Introducing SgRNA/Cas9 Expressing Plasmids
  Methods in Molecular Biology (Clifton, N.J.). 2017  |   Pubmed ID: 28643250
• TCTE1 is a Conserved Component of the Dynein Regulatory Complex and is Required for Motility and Metabolism in Mouse Spermatozoa
  Proceedings of the National Academy of Sciences of the United States of America. 07, 2017  |   Pubmed ID: 28630322
• Structural and Functional Insights into IZUMO1 Recognition by JUNO in Mammalian Fertilization
  Nature Communications. 07, 2016  |   Pubmed ID: 27416963
• Essential Role of Autoactivation Circuitry on Aurora B-mediated H2AX-pS121 in Mitosis
  Nature Communications. 07, 2016  |   Pubmed ID: 27389782
• Ground-based Assessment of JAXA Mouse Habitat Cage Unit by Mouse Phenotypic Studies
  Experimental Animals. May, 2016  |   Pubmed ID: 26822934
• Liver-specific γ-glutamyl Carboxylase-deficient Mice Display Bleeding Diathesis and Short Life Span
  PloS One. 2014  |   Pubmed ID: 24520408
• Innate Versus Learned Odour Processing in the Mouse Olfactory Bulb
  Nature. Nov, 2007  |   Pubmed ID: 17989651