Massimo Negrini

Publications

• Dissecting Chronic Lymphocytic Leukemia with 13q- Using MicroRNA Expression Profile: Editorial for the Paper "MiRNA Expression Profile of Chronic Lymphocytic Leukemia Patients with 13q Deletion"
  Leukemia Research. May, 2016  |   Pubmed ID: 27304710
• Over-expression of the MiR-483-3p Overcomes the MiR-145/TP53 Pro-apoptotic Loop in Hepatocellular Carcinoma
  Oncotarget. Apr, 2016  |   Pubmed ID: 27120784
• MiRNA Array Screening Reveals Cooperative MGMT-regulation Between MiR-181d-5p and MiR-409-3p in Glioblastoma
  Oncotarget. Apr, 2016  |   Pubmed ID: 27057640
• MicroRNA Profiling of Primary Pulmonary Enteric Adenocarcinoma in Members from the Same Family Reveals Some Similarities to Pancreatic Adenocarcinoma-a Step Towards Personalized Therapy
  Clinical Epigenetics. 2015  |   Pubmed ID: 26677401
• Circulating MicroRNAs, MiR-939, MiR-595, MiR-519d and MiR-494, Identify Cirrhotic Patients with HCC
  PloS One. 2015  |   Pubmed ID: 26509672
• Prediction of Response to Anti-EGFR Antibody-based Therapies by Multigene Sequencing in Colorectal Cancer Patients
  BMC Cancer. 2015  |   Pubmed ID: 26508446
• MicroRNA Expression Profiling Identifies MiR-31-5p/3p As Associated with Time to Progression in Wild-type RAS Metastatic Colorectal Cancer Treated with Cetuximab
  Oncotarget. Nov, 2015  |   Pubmed ID: 26497852
• Interspecies Gene Name Extrapolation--A New Approach
  PloS One. 2015  |   Pubmed ID: 26407293
• Chromosome Aberrations Detected by Conventional Karyotyping Using Novel Mitogens in Chronic Lymphocytic Leukemia: Clinical and Biologic Correlations
  Genes, Chromosomes & Cancer. Dec, 2015  |   Pubmed ID: 26355802
• Micromarkers 2.0: an Update on the Role of MicroRNAs in Cancer Diagnosis and Prognosis
  Expert Review of Molecular Diagnostics. 2015  |   Pubmed ID: 26338209
• Epstein-Barr Virus MicroRNAs Are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival
  EBioMedicine. Jun, 2015  |   Pubmed ID: 26288818
• Diagnostic and Prognostic MicroRNAs in the Serum of Breast Cancer Patients Measured by Droplet Digital PCR
  Biomarker Research. 2015  |   Pubmed ID: 26120471
• MiR-181b As a Therapeutic Agent for Chronic Lymphocytic Leukemia in the Eµ-TCL1 Mouse Model
  Oncotarget. Aug, 2015  |   Pubmed ID: 26090867
• Absolute Quantification of Cell-free MicroRNAs in Cancer Patients
  Oncotarget. Jun, 2015  |   Pubmed ID: 26036630
• Association Between Gene and MiRNA Expression Profiles and Stereotyped Subset #4 B-cell Receptor in Chronic Lymphocytic Leukemia
  Leukemia & Lymphoma. 2015  |   Pubmed ID: 25860243
• Increase of MicroRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins Following Mithramycin Treatment of Human Erythroid Cells
  PloS One. 2015  |   Pubmed ID: 25849663
• Mesenchymal Progenitors Aging Highlights a MiR-196 Switch Targeting HOXB7 As Master Regulator of Proliferation and Osteogenesis
  Stem Cells (Dayton, Ohio). Mar, 2015  |   Pubmed ID: 25428821
• Gene Expression Changes in Progression of Cervical Neoplasia Revealed by Microarray Analysis of Cervical Neoplastic Keratinocytes
  Journal of Cellular Physiology. Apr, 2015  |   Pubmed ID: 25205602
• Quantification of Circulating MiRNAs by Droplet Digital PCR: Comparison of EvaGreen- and TaqMan-based Chemistries
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Dec, 2014  |   Pubmed ID: 25472671
• Inhibiting the Oncogenic Mir-221 by MicroRNA Sponge: Toward MicroRNA-based Therapeutics for Hepatocellular Carcinoma
  Gastroenterology and Hepatology from Bed to Bench. 2014  |   Pubmed ID: 25436097
• Pluripotent Stem Cell MiRNAs and Metastasis in Invasive Breast Cancer
  Journal of the National Cancer Institute. Dec, 2014  |   Pubmed ID: 25306216
• OncomiR Detection in Circulating Body Fluids: a PDMS Microdevice Perspective
  Lab on a Chip. Oct, 2014  |   Pubmed ID: 25178053
• MicroRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2014  |   Pubmed ID: 24916701
• Modern Treatment in Chronic Lymphocytic Leukemia: Impact on Survival and Efficacy in High-risk Subgroups
  Cancer Medicine. Jun, 2014  |   Pubmed ID: 24648042
• Genetic Subclonal Complexity and MiR125a-5p Down-regulation Identify a Subset of Patients with Inferior Outcome in Low-risk CLL Patients
  Oncotarget. Jan, 2014  |   Pubmed ID: 24334759
• P53/mdm2 Feedback Loop Sustains MiR-221 Expression and Dictates the Response to Anticancer Treatments in Hepatocellular Carcinoma
  Molecular Cancer Research : MCR. Feb, 2014  |   Pubmed ID: 24324033
• STAT3-mediated Activation of MicroRNA Cluster 17~92 Promotes Proliferation and Survival of ALK-positive Anaplastic Large Cell Lymphoma
  Haematologica. Jan, 2014  |   Pubmed ID: 23975180
• MiR-125b Targets Erythropoietin and Its Receptor and Their Expression Correlates with Metastatic Potential and ERBB2/HER2 Expression
  Molecular Cancer. 2013  |   Pubmed ID: 24165569
• Anti-tumor Activity of a MiR-199-dependent Oncolytic Adenovirus
  PloS One. 2013  |   Pubmed ID: 24069256
• First Report of Circulating MicroRNAs in Tumour Necrosis Factor Receptor-associated Periodic Syndrome (TRAPS)
  PloS One. 2013  |   Pubmed ID: 24066048
• Role of MicroRNAs in Hepatocellular Carcinoma: a Clinical Perspective
  OncoTargets and Therapy. 2013  |   Pubmed ID: 24039437
• Clinical Monoclonal B Lymphocytosis Versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2013  |   Pubmed ID: 24036852
• Small Nucleolar RNAs As New Biomarkers in Chronic Lymphocytic Leukemia
  BMC Medical Genomics. 2013  |   Pubmed ID: 24004562
• CCAT2, a Novel Non-coding RNA Mapping to 8q24, Underlies Metastatic Progression and Chromosomal Instability in Colon Cancer
  Genome Research. Jun, 2013  |   Pubmed ID: 23796952
• MiR-221 Affects Multiple Cancer Pathways by Modulating the Level of Hundreds Messenger RNAs
  Frontiers in Genetics. 2013  |   Pubmed ID: 23630541
• MiR-126&126* Restored Expressions Play a Tumor Suppressor Role by Directly Regulating ADAM9 and MMP7 in Melanoma
  PloS One. 2013  |   Pubmed ID: 23437250
• BCR/ABL1-positive Acute Lymphoblastic Leukemia Relapsing As BCR/ABL1-negative Acute Lymphoblastic Leukemia
  Leukemia & Lymphoma. Sep, 2013  |   Pubmed ID: 23323950
• Downregulation of the Mitochondrial Calcium Uniporter by Cancer-related MiR-25
  Current Biology : CB. Jan, 2013  |   Pubmed ID: 23246404
• DNA-demethylating and Anti-tumor Activity of Synthetic MiR-29b Mimics in Multiple Myeloma
  Oncotarget. Oct, 2012  |   Pubmed ID: 23100393
• Synthetic MiR-34a Mimics As a Novel Therapeutic Agent for Multiple Myeloma: in Vitro and in Vivo Evidence
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2012  |   Pubmed ID: 23035210
• Liver Tumorigenicity Promoted by MicroRNA-221 in a Mouse Transgenic Model
  Hepatology (Baltimore, Md.). Sep, 2012  |   Pubmed ID: 22473819
• In Hepatocellular Carcinoma MiR-519d is Up-regulated by P53 and DNA Hypomethylation and Targets CDKN1A/p21, PTEN, AKT3 and TIMP2
  The Journal of Pathology. Jul, 2012  |   Pubmed ID: 22262409
• Chromosome Aberrations Detected by Conventional Karyotyping Using Novel Mitogens in Chronic Lymphocytic Leukemia with "normal" FISH: Correlations with Clinicobiologic Parameters
  Blood. Mar, 2012  |   Pubmed ID: 22246039
• MINT31 Methylation in Gastric Noninvasive Neoplasia: Potential Role in the Secondary Prevention of Gastric Cancer
  European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). Sep, 2012  |   Pubmed ID: 22179688
• MiR-34a Predicts Survival of Ewing's Sarcoma Patients and Directly Influences Cell Chemo-sensitivity and Malignancy
  The Journal of Pathology. Apr, 2012  |   Pubmed ID: 21960059
• MicroRNAs: Toward the Clinic for Breast Cancer Patients
  Seminars in Oncology. Dec, 2011  |   Pubmed ID: 22082762
• MicroRNA Profiling for the Identification of Cancers with Unknown Primary Tissue-of-origin
  The Journal of Pathology. Sep, 2011  |   Pubmed ID: 21630269
• MicroRNA Involvement in Hepatocellular Carcinoma
  Anti-cancer Agents in Medicinal Chemistry. Jul, 2011  |   Pubmed ID: 21554203
• MicroRNA Response to Environmental Mutagens in Liver
  Mutation Research. Dec, 2011  |   Pubmed ID: 21514310
• Mutated Beta-catenin Evades a MicroRNA-dependent Regulatory Loop
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011  |   Pubmed ID: 21383185
• MicroRNAs Dysregulation in Human Malignant Pleural Mesothelioma
  Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. May, 2011  |   Pubmed ID: 21358347
• Association of a MicroRNA/TP53 Feedback Circuitry with Pathogenesis and Outcome of B-cell Chronic Lymphocytic Leukemia
  JAMA. Jan, 2011  |   Pubmed ID: 21205967
• MicroRNA-mediated Regulation of Pancreatic Cancer Cell Proliferation
  Oncology Letters. May, 2010  |   Pubmed ID: 22966344
• Altered MiRNA Expression in T Regulatory Cells in Course of Multiple Sclerosis
  Journal of Neuroimmunology. Sep, 2010  |   Pubmed ID: 20637509
• MicroRNAs Involvement in Fludarabine Refractory Chronic Lymphocytic Leukemia
  Molecular Cancer. 2010  |   Pubmed ID: 20504344
• MiR-199a-3p Regulates MTOR and C-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
  Cancer Research. Jun, 2010  |   Pubmed ID: 20501828
• Reprogramming of MiRNA Networks in Cancer and Leukemia
  Genome Research. May, 2010  |   Pubmed ID: 20439436
• MicroRNA Fingerprinting of CLL Patients with Chromosome 17p Deletion Identify a MiR-21 Score That Stratifies Early Survival
  Blood. Aug, 2010  |   Pubmed ID: 20393129
• Oncogenic Role of MiR-483-3p at the IGF2/483 Locus
  Cancer Research. Apr, 2010  |   Pubmed ID: 20388800
• Micromarkers: MiRNAs in Cancer Diagnosis and Prognosis
  Expert Review of Molecular Diagnostics. Apr, 2010  |   Pubmed ID: 20370587
• Modulation of Mismatch Repair and Genomic Stability by MiR-155
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010  |   Pubmed ID: 20351277
• Differential Cytogenomics and MiRNA Signature of the Acute Myeloid Leukaemia Kasumi-1 Cell Line CD34+38- Compartment
  Leukemia Research. Oct, 2010  |   Pubmed ID: 20227111
• Non-coding RNAs Change Their Expression Profile After Retinoid Induced Differentiation of the Promyelocytic Cell Line NB4
  BMC Research Notes. 2010  |   Pubmed ID: 20181027
• Clinicobiologic Importance of Cytogenetic Lesions in Chronic Lymphocytic Leukemia
  Expert Review of Hematology. Jun, 2009  |   Pubmed ID: 21082972
• MicroRNA Fingerprints Identify MiR-150 As a Plasma Prognostic Marker in Patients with Sepsis
  PloS One. 2009  |   Pubmed ID: 19823581
• Karyotype-specific MicroRNA Signature in Chronic Lymphocytic Leukemia
  Blood. Oct, 2009  |   Pubmed ID: 19717645
• MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2009  |   Pubmed ID: 19671867
• MiR-122/cyclin G1 Interaction Modulates P53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
  Cancer Research. Jul, 2009  |   Pubmed ID: 19584283
• MicroRNAs and Cancer--new Paradigms in Molecular Oncology
  Current Opinion in Cell Biology. Jun, 2009  |   Pubmed ID: 19411171
• MicroRNA Expression Changes During Human Leukemic HL-60 Cell Differentiation Induced by 4-hydroxynonenal, a Product of Lipid Peroxidation
  Free Radical Biology & Medicine. Jan, 2009  |   Pubmed ID: 19022373
• MicroRNA Involvement in Hepatocellular Carcinoma
  Journal of Cellular and Molecular Medicine. Dec, 2008  |   Pubmed ID: 19120703
• Genome Wide Identification of Recessive Cancer Genes by Combinatorial Mutation Analysis
  PloS One. 2008  |   Pubmed ID: 18846217
• Isolation and Characterization of CD146+ Multipotent Mesenchymal Stromal Cells
  Experimental Hematology. Aug, 2008  |   Pubmed ID: 18504067
• Breast Cancer Metastasis: a MicroRNA Story
  Breast Cancer Research : BCR. 2008  |   Pubmed ID: 18373886
• MiR-15a and MiR-16-1 Cluster Functions in Human Leukemia
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008  |   Pubmed ID: 18362358
• E2F1-regulated MicroRNAs Impair TGFbeta-dependent Cell-cycle Arrest and Apoptosis in Gastric Cancer
  Cancer Cell. Mar, 2008  |   Pubmed ID: 18328430
• Micro-RNA Profiling in Kidney and Bladder Cancers
  Urologic Oncology. Sep-Oct, 2007  |   Pubmed ID: 17826655
• Ultraconserved Regions Encoding NcRNAs Are Altered in Human Leukemias and Carcinomas
  Cancer Cell. Sep, 2007  |   Pubmed ID: 17785203
• MRNA/microRNA Gene Expression Profile in Microsatellite Unstable Colorectal Cancer
  Molecular Cancer. 2007  |   Pubmed ID: 17716371
• Tumor Suppressor Functions of ARLTS1 in Lung Cancers
  Cancer Research. Aug, 2007  |   Pubmed ID: 17699778
• Regulatory Mechanisms of MicroRNAs Involvement in Cancer
  Expert Opinion on Biological Therapy. Jul, 2007  |   Pubmed ID: 17665990
• Cyclin G1 is a Target of MiR-122a, a MicroRNA Frequently Down-regulated in Human Hepatocellular Carcinoma
  Cancer Research. Jul, 2007  |   Pubmed ID: 17616664
• Regulation of MicroRNA Expression: the Hypoxic Component
  Cell Cycle (Georgetown, Tex.). Jun, 2007  |   Pubmed ID: 17582223
• MicroRNAs in Human Cancer: from Research to Therapy
  Journal of Cell Science. Jun, 2007  |   Pubmed ID: 17515481
• Nidogen 1 and 2 Gene Promoters Are Aberrantly Methylated in Human Gastrointestinal Cancer
  Molecular Cancer. 2007  |   Pubmed ID: 17328794
• A MicroRNA Signature of Hypoxia
  Molecular and Cellular Biology. Mar, 2007  |   Pubmed ID: 17194750
• Mechanisms Causing Imprinting Defects in Familial Beckwith-Wiedemann Syndrome with Wilms' Tumour
  Human Molecular Genetics. Feb, 2007  |   Pubmed ID: 17158821
• Identification of Differentially Expressed MicroRNAs by Microarray: a Possible Role for MicroRNA Genes in Pituitary Adenomas
  Journal of Cellular Physiology. Feb, 2007  |   Pubmed ID: 17111382
• Alterations of the Tumor Suppressor Gene ARLTS1 in Ovarian Cancer
  Cancer Research. Nov, 2006  |   Pubmed ID: 17079447
• BK Virus, JC Virus and Simian Virus 40 Infection in Humans, and Association with Human Tumors
  Advances in Experimental Medicine and Biology. 2006  |   Pubmed ID: 16626046
• A MicroRNA Expression Signature of Human Solid Tumors Defines Cancer Gene Targets
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006  |   Pubmed ID: 16461460
• Identification of NUP98 Abnormalities in Acute Leukemia: JARID1A (12p13) As a New Partner Gene
  Genes, Chromosomes & Cancer. May, 2006  |   Pubmed ID: 16419055
• Neoplastic Circulating Endothelial Cells in Multiple Myeloma with 13q14 Deletion
  Blood. Mar, 2006  |   Pubmed ID: 16317105
• A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia
  The New England Journal of Medicine. Oct, 2005  |   Pubmed ID: 16251535
• MiR-15 and MiR-16 Induce Apoptosis by Targeting BCL2
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005  |   Pubmed ID: 16166262
• MicroRNA Gene Expression Deregulation in Human Breast Cancer
  Cancer Research. Aug, 2005  |   Pubmed ID: 16103053
• Familial Cancer Associated with a Polymorphism in ARLTS1
  The New England Journal of Medicine. Apr, 2005  |   Pubmed ID: 15843669
• Adenoviral Transduction of TESTIN Gene into Breast and Uterine Cancer Cell Lines Promotes Apoptosis and Tumor Reduction in Vivo
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2005  |   Pubmed ID: 15701871
• Frequent Aberrant Methylation of the CDH4 Gene Promoter in Human Colorectal and Gastric Cancer
  Cancer Research. Nov, 2004  |   Pubmed ID: 15548679
• Cryptic Insertion Producing Two NUP98/NSD1 Chimeric Transcripts in Adult Refractory Anemia with an Excess of Blasts
  Genes, Chromosomes & Cancer. Dec, 2004  |   Pubmed ID: 15382262
• MicroRNA Profiling Reveals Distinct Signatures in B Cell Chronic Lymphocytic Leukemias
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004  |   Pubmed ID: 15284443
• An Oligonucleotide Microchip for Genome-wide MicroRNA Profiling in Human and Mouse Tissues
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004  |   Pubmed ID: 15210942
• Simian Virus 40 Infection in Humans and Association with Human Diseases: Results and Hypotheses
  Virology. Jan, 2004  |   Pubmed ID: 15015494
• Human MicroRNA Genes Are Frequently Located at Fragile Sites and Genomic Regions Involved in Cancers
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004  |   Pubmed ID: 14973191
• Multigene Methylation Analysis of Gastrointestinal Tumors: TPEF Emerges As a Frequent Tumor-specific Aberrantly Methylated Marker That Can Be Detected in Peripheral Blood
  Molecular Diagnosis : a Journal Devoted to the Understanding of Human Disease Through the Clinical Application of Molecular Biology. 2003  |   Pubmed ID: 15068392
• The BCSC-1 Locus at Chromosome 11q23-q24 is a Candidate Tumor Suppressor Gene
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003  |   Pubmed ID: 14504409
• Oncogenic Transformation by BK Virus and Association with Human Tumors
  Oncogene. Aug, 2003  |   Pubmed ID: 12910256
• Human Homeobox Gene HOXC13 is the Partner of NUP98 in Adult Acute Myeloid Leukemia with T(11;12)(p15;q13)
  Genes, Chromosomes & Cancer. Apr, 2003  |   Pubmed ID: 12619167
• Genetic Chaos and Antichaos in Human Cancers
  Medical Hypotheses. Feb, 2003  |   Pubmed ID: 12606244
• Frequent Deletions and Down-regulation of Micro- RNA Genes MiR15 and MiR16 at 13q14 in Chronic Lymphocytic Leukemia
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002  |   Pubmed ID: 12434020
• Cloning and Characterization of the Common Fragile Site FRA6F Harboring a Replicative Senescence Gene and Frequently Deleted in Human Tumors
  Oncogene. Oct, 2002  |   Pubmed ID: 12370818
• NUP98 is Fused to the NSD3 Gene in Acute Myeloid Leukemia Associated with T(8;11)(p11.2;p15)
  Blood. May, 2002  |   Pubmed ID: 11986249
• Loss of Methylation at Chromosome 11p15.5 is Common in Human Adult Tumors
  Oncogene. Apr, 2002  |   Pubmed ID: 11971191
• Late Appearance of the 11q22.3-23.1 Deletion Involving the ATM Locus in B-cell Chronic Lymphocytic Leukemia and Related Disorders. Clinico-biological Significance
  Haematologica. Jan, 2002  |   Pubmed ID: 11801464