Matt Kaeberlein Department of Pathology University of Washington Biography Publications Institution JoVE Articles Matt Kaeberlein has not added a biography. If you are Matt Kaeberlein and would like to personalize this page please email our Author Liaison for assistance. Publications The Antifungal Plant Defensin HsAFP1 Induces Autophagy, Vacuolar Dysfunction and Cell Cycle Impairment in Yeast Biochimica Et Biophysica Acta. Biomembranes. Mar, 2020 | Pubmed ID: 32145284 Loss of Vacuolar Acidity Results in Iron-sulfur Cluster Defects and Divergent Homeostatic Responses During Aging in Saccharomyces Cerevisiae GeroScience. Jan, 2020 | Pubmed ID: 31975050 Rb Analog Whi5 Regulates G1 to S Transition and Cell Size but Not Replicative Lifespan in Budding Yeast Translational Medicine of Aging. 2019 | Pubmed ID: 32190787 DDS Promotes Longevity Through a Microbiome-mediated Starvation Signal Translational Medicine of Aging. 2019 | Pubmed ID: 32190786 Chaperone Biomarkers of Lifespan and Penetrance Track the Dosages of Many Other Proteins Nature Communications. 12, 2019 | Pubmed ID: 31844058 Desexing Dogs: A Review of the Current Literature Animals : an Open Access Journal from MDPI. Dec, 2019 | Pubmed ID: 31817504 Latest Advances in Aging Research and Drug Discovery Aging. 11, 2019 | Pubmed ID: 31770722 WormBot, an Open-source Robotics Platform for Survival and Behavior Analysis in C. Elegans GeroScience. 12, 2019 | Pubmed ID: 31728898 DNA Damage Checkpoint Activation Impairs Chromatin Homeostasis and Promotes Mitotic Catastrophe During Aging ELife. 11, 2019 | Pubmed ID: 31714209 Cross Species Application of Quantitative Neuropathology Assays Developed for Clinical Alzheimer's Disease Samples Pathobiology of Aging & Age Related Diseases. 2019 | Pubmed ID: 31528297 An Inexpensive Microscopy System for Microfluidic Studies in Budding Yeast Translational Medicine of Aging. 2019 | Pubmed ID: 31511839 Trajectories of Aging: How Systems Biology in Yeast Can Illuminate Mechanisms of Personalized Aging Proteomics. Aug, 2019 | Pubmed ID: 31385433 Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the RDNA of Genetics. 09, 2019 | Pubmed ID: 31292210 In Vivo Measurements Reveal a Single 5'-intron is Sufficient to Increase Protein Expression Level in Caenorhabditis Elegans Scientific Reports. Jun, 2019 | Pubmed ID: 31235724 Age-dependent Deterioration of Nuclear Pore Assembly in Mitotic Cells Decreases Transport Dynamics ELife. 06, 2019 | Pubmed ID: 31157618 Defining the Impact of Mutation Accumulation on Replicative Lifespan in Yeast Using Cancer-associated Mutator Phenotypes Proceedings of the National Academy of Sciences of the United States of America. 02, 2019 | Pubmed ID: 30718408 Rapamycin and Alzheimer's Disease: Time for a Clinical Trial? Science Translational Medicine. 01, 2019 | Pubmed ID: 30674654 MTOR Inhibitors May Benefit Kidney Transplant Recipients with Mitochondrial Diseases Kidney International. 02, 2019 | Pubmed ID: 30471880 Electrophysiological Measures of Aging Pharynx Function in C. Elegans Reveal Enhanced Organ Functionality in Older, Long-lived Mutants The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jul, 2019 | Pubmed ID: 29165668 Research to Promote Longevity and Health Span in Companion Dogs: A Pediatric Perspective The American Journal of Bioethics : AJOB. Oct, 2018 | Pubmed ID: 30339074 Genetic Screen Identifies Adaptive Aneuploidy As a Key Mediator of ER Stress Resistance in Yeast Proceedings of the National Academy of Sciences of the United States of America. Sep, 2018 | Pubmed ID: 30185560 How Healthy is the Healthspan Concept? GeroScience. 08, 2018 | Pubmed ID: 30084059 Reactivation of RNA Metabolism Underlies Somatic Restoration After Adult Reproductive Diapause in ELife. 08, 2018 | Pubmed ID: 30070633 The Paths of Mortality: How Understanding the Biology of Aging Can Help Explain Systems Behavior of Single Cells Current Opinion in Systems Biology. Apr, 2018 | Pubmed ID: 29552673 Oral Health in Geroscience: Animal Models and the Aging Oral Cavity GeroScience. 02, 2018 | Pubmed ID: 29282653 Translational Geroscience: A New Paradigm for 21 Century Medicine Translational Medicine of Aging. Oct, 2017 | Pubmed ID: 32219192 Corrigendum: Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency Frontiers in Genetics. 2017 | Pubmed ID: 29285026 Genetic Interaction with Temperature is an Important Determinant of Nematode Longevity Aging Cell. 12, 2017 | Pubmed ID: 28940623 Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency Frontiers in Genetics. 2017 | Pubmed ID: 28919908 Rapamycin Treatment Attenuates Age-associated Periodontitis in Mice GeroScience. Aug, 2017 | Pubmed ID: 28889220 A System to Identify Inhibitors of MTOR Signaling Using High-resolution Growth Analysis in Saccharomyces Cerevisiae GeroScience. Aug, 2017 | Pubmed ID: 28707282 Inter-organ Regulation of Haem Homeostasis Nature Cell Biology. Jun, 2017 | Pubmed ID: 28659637 Flavin-containing Monooxygenases in Aging and Disease: Emerging Roles for Ancient Enzymes The Journal of Biological Chemistry. 07, 2017 | Pubmed ID: 28515321 A Randomized Controlled Trial to Establish Effects of Short-term Rapamycin Treatment in 24 Middle-aged Companion Dogs GeroScience. 04, 2017 | Pubmed ID: 28374166 Environmental Canalization of Life Span and Gene Expression in Caenorhabditis Elegans The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Aug, 2017 | Pubmed ID: 28369388 Transaldolase Inhibition Impairs Mitochondrial Respiration and Induces a Starvation-like Longevity Response in Caenorhabditis Elegans PLoS Genetics. Mar, 2017 | Pubmed ID: 28355222 Asymptomatic Heart Valve Dysfunction in Healthy Middle-aged Companion Dogs and Its Implications for Cardiac Aging GeroScience. 02, 2017 | Pubmed ID: 28299636 Systems Biology Approach to Late-onset Alzheimer's Disease Genome-wide Association Study Identifies Novel Candidate Genes Validated Using Brain Expression Data and Caenorhabditis Elegans Experiments Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Oct, 2017 | Pubmed ID: 28242297 CAN1 Arginine Permease Deficiency Extends Yeast Replicative Lifespan Via Translational Activation of Stress Response Genes Cell Reports. Feb, 2017 | Pubmed ID: 28228255 Dietary Restriction and Lifespan: Lessons from Invertebrate Models Ageing Research Reviews. Oct, 2017 | Pubmed ID: 28007498 Microfluidic Technologies for Yeast Replicative Lifespan Studies Mechanisms of Ageing and Development. 01, 2017 | Pubmed ID: 27015709 Rapamycin Enhances Survival in a Drosophila Model of Mitochondrial Disease Oncotarget. Dec, 2016 | Pubmed ID: 27741510 Age-associated Vulval Integrity is an Important Marker of Nematode Healthspan Age (Dordrecht, Netherlands). Dec, 2016 | Pubmed ID: 27566309 Transient Rapamycin Treatment Can Increase Lifespan and Healthspan in Middle-aged Mice ELife. 08, 2016 | Pubmed ID: 27549339 Rapamycin in Aging and Disease: Maximizing Efficacy While Minimizing Side Effects Oncotarget. Jul, 2016 | Pubmed ID: 27384492 New Insights into Cell Non-autonomous Mechanisms of the C. Elegans Hypoxic Response Worm. Apr-Jun, 2016 | Pubmed ID: 27383456 New Functional and Biophysical Insights into the Mitochondrial Rieske Iron-sulfur Protein from Genetic Suppressor Analysis in C. Elegans Worm. Apr-Jun, 2016 | Pubmed ID: 27383074 The Dog Aging Project: Translational Geroscience in Companion Animals Mammalian Genome : Official Journal of the International Mammalian Genome Society. 08, 2016 | Pubmed ID: 27143112 Aneuploidy Shortens Replicative Lifespan in Saccharomyces Cerevisiae Aging Cell. Apr, 2016 | Pubmed ID: 26762766 The Biology of Aging: Citizen Scientists and Their Pets As a Bridge Between Research on Model Organisms and Human Subjects Veterinary Pathology. Mar, 2016 | Pubmed ID: 26077786 Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates NPJ Aging and Mechanisms of Disease. 2015 | Pubmed ID: 27030810 Healthy Aging: The Ultimate Preventative Medicine Science (New York, N.Y.). Dec, 2015 | Pubmed ID: 26785476 Cell Nonautonomous Activation of Flavin-containing Monooxygenase Promotes Longevity and Health Span Science (New York, N.Y.). Dec, 2015 | Pubmed ID: 26586189 Sorbitol Treatment Extends Lifespan and Induces the Osmotic Stress Response in Caenorhabditis Elegans Frontiers in Genetics. 2015 | Pubmed ID: 26579191 Biochemical Genetic Pathways That Modulate Aging in Multiple Species Cold Spring Harbor Perspectives in Medicine. Nov, 2015 | Pubmed ID: 26525455 Tether Mutations That Restore Function and Suppress Pleiotropic Phenotypes of the C. Elegans Isp-1(qm150) Rieske Iron-sulfur Protein Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26504246 A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging Cell Metabolism. Nov, 2015 | Pubmed ID: 26456335 Systematic Analysis of Asymmetric Partitioning of Yeast Proteome Between Mother and Daughter Cells Reveals "aging Factors" and Mechanism of Lifespan Asymmetry Proceedings of the National Academy of Sciences of the United States of America. Sep, 2015 | Pubmed ID: 26351681 Transcription Errors Induce Proteotoxic Stress and Shorten Cellular Lifespan Nature Communications. Aug, 2015 | Pubmed ID: 26304740 Dose-dependent Effects of MTOR Inhibition on Weight and Mitochondrial Disease in Mice Frontiers in Genetics. 2015 | Pubmed ID: 26257774 H3K36 Methylation Promotes Longevity by Enhancing Transcriptional Fidelity Genes & Development. Jul, 2015 | Pubmed ID: 26159996 MicroRNA Transcriptome Analysis Identifies MiR-365 As a Novel Negative Regulator of Cell Proliferation in Zmpste24-deficient Mouse Embryonic Fibroblasts Mutation Research. Jul, 2015 | Pubmed ID: 25983189 PMT1 Deficiency Enhances Basal UPR Activity and Extends Replicative Lifespan of Saccharomyces Cerevisiae Age (Dordrecht, Netherlands). Jun, 2015 | Pubmed ID: 25936926 Why is Aging Conserved and What Can We Do About It? PLoS Biology. Apr, 2015 | Pubmed ID: 25923592 Fertile Waters for Aging Research Cell. Feb, 2015 | Pubmed ID: 25723160 Syringaresinol Protects Against Hypoxia/reoxygenation-induced Cardiomyocytes Injury and Death by Destabilization of HIF-1α in a FOXO3-dependent Mechanism Oncotarget. Jan, 2015 | Pubmed ID: 25415049 Modulating MTOR in Aging and Health Interdisciplinary Topics in Gerontology. 2015 | Pubmed ID: 25341517 Searching for the Elusive Mitochondrial Longevity Signal in C. Elegans Worm. Jul-Sep, 2014 | Pubmed ID: 26430544 Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast Through Inhibition of Tryptophan Import PLoS Genetics. Dec, 2014 | Pubmed ID: 25521617 Rapamycin and Ageing: When, for How Long, and How Much? Journal of Genetics and Genomics = Yi Chuan Xue Bao. Sep, 2014 | Pubmed ID: 25269671 Replicative Life Span Analysis in Budding Yeast Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25213254 A Drosophila Model of Mitochondrial Disease Caused by a Complex I Mutation That Uncouples Proton Pumping from Electron Transfer Disease Models & Mechanisms. Oct, 2014 | Pubmed ID: 25085991 The SAGA Histone Deubiquitinase Module Controls Yeast Replicative Lifespan Via Sir2 Interaction Cell Reports. Jul, 2014 | Pubmed ID: 25043177 Rejuvenation: It's in Our Blood Cell Metabolism. Jul, 2014 | Pubmed ID: 24988454 Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction Via Induction of Genotoxic Stress Response Cell Metabolism. Jun, 2014 | Pubmed ID: 24814484 Activation of the Mitochondrial Unfolded Protein Response Does Not Predict Longevity in Caenorhabditis Elegans Nature Communications. Mar, 2014 | Pubmed ID: 24662282 The Mitochondrial Unfolded Protein Response and Increased Longevity: Cause, Consequence, or Correlation? Experimental Gerontology. Aug, 2014 | Pubmed ID: 24518875 Nar1 Deficiency Results in Shortened Lifespan and Sensitivity to Paraquat That is Rescued by Increased Expression of Mitochondrial Superoxide Dismutase Mechanisms of Ageing and Development. Jun, 2014 | Pubmed ID: 24486555 Development. Chemical Warfare in the Battle of the Sexes Science (New York, N.Y.). Jan, 2014 | Pubmed ID: 24482469 Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response PLoS Genetics. Jan, 2014 | Pubmed ID: 24391512 Yeast Replicative Aging: a Paradigm for Defining Conserved Longevity Interventions FEMS Yeast Research. Feb, 2014 | Pubmed ID: 24119093 Buffering the PH of the Culture Medium Does Not Extend Yeast Replicative Lifespan F1000Research. 2013 | Pubmed ID: 24555104 MTOR Inhibition: From Aging to Autism and Beyond Scientifica. 2013 | Pubmed ID: 24379984 UV-photoconversion of Ethosuximide from a Longevity-promoting Compound to a Potent Toxin PloS One. 2013 | Pubmed ID: 24340038 MTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome Science (New York, N.Y.). Dec, 2013 | Pubmed ID: 24231806 Deciphering the Role of Natural Variation in Age-related Protein Homeostasis BMC Biology. Sep, 2013 | Pubmed ID: 24228595 Preserving Youth: Does Rapamycin Deliver? Science Translational Medicine. Nov, 2013 | Pubmed ID: 24225941 The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1 PLoS Genetics. 2013 | Pubmed ID: 23990801 Molecular Mechanisms Underlying Genotype-dependent Responses to Dietary Restriction Aging Cell. Jul, 2013 | Pubmed ID: 23837470 Longevity and Aging F1000prime Reports. 2013 | Pubmed ID: 23513177 A Natural Polymorphism in RDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan PLoS Genetics. 2013 | Pubmed ID: 23505383 Life-span Extension from Hypoxia in Caenorhabditis Elegans Requires Both HIF-1 and DAF-16 and is Antagonized by SKN-1 The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Oct, 2013 | Pubmed ID: 23419779 End-of-life Cell Cycle Arrest Contributes to Stochasticity of Yeast Replicative Aging FEMS Yeast Research. May, 2013 | Pubmed ID: 23336757 MTOR is a Key Modulator of Ageing and Age-related Disease Nature. Jan, 2013 | Pubmed ID: 23325216 Dietary Restriction and Mitochondrial Function Link Replicative and Chronological Aging in Saccharomyces Cerevisiae Experimental Gerontology. Oct, 2013 | Pubmed ID: 23235143 Stress Profiling of Longevity Mutants Identifies Afg3 As a Mitochondrial Determinant of Cytoplasmic MRNA Translation and Aging Aging Cell. Feb, 2013 | Pubmed ID: 23167605 Elevated MTORC1 Signaling and Impaired Autophagy Autophagy. Jan, 2013 | Pubmed ID: 23064282 Caffeine Extends Life Span, Improves Healthspan, and Delays Age-associated Pathology in Caenorhabditis Elegans Longevity & Healthspan. 2012 | Pubmed ID: 24764514 Genome-Wide RNAi Longevity Screens in Caenorhabditis Elegans Current Genomics. Nov, 2012 | Pubmed ID: 23633911 PH Neutralization Protects Against Reduction in Replicative Lifespan Following Chronological Aging in Yeast Cell Cycle (Georgetown, Tex.). Aug, 2012 | Pubmed ID: 22871733 Rapamycin Reverses Elevated MTORC1 Signaling in Lamin A/C-deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival Science Translational Medicine. Jul, 2012 | Pubmed ID: 22837538 Yeast As a Model to Understand the Interaction Between Genotype and the Response to Calorie Restriction FEBS Letters. Aug, 2012 | Pubmed ID: 22828279 Replicative and Chronological Aging in Saccharomyces Cerevisiae Cell Metabolism. Jul, 2012 | Pubmed ID: 22768836 Midlife Gene Expressions Identify Modulators of Aging Through Dietary Interventions Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22509016 Ribosome Deficiency Protects Against ER Stress in Saccharomyces Cerevisiae Genetics. May, 2012 | Pubmed ID: 22377630 A New Chronological Survival Assay in Mammalian Cell Culture Cell Cycle (Georgetown, Tex.). Jan, 2012 | Pubmed ID: 22214665 Genome-wide Analysis of Yeast Aging Sub-cellular Biochemistry. 2012 | Pubmed ID: 22094426 The MDT-15 Subunit of Mediator Interacts with Dietary Restriction to Modulate Longevity and Fluoranthene Toxicity in Caenorhabditis Elegans PloS One. 2011 | Pubmed ID: 22132200 Composition and Acidification of the Culture Medium Influences Chronological Aging Similarly in Vineyard and Laboratory Yeast PloS One. 2011 | Pubmed ID: 21949725 Absence of Effects of Sir2 Overexpression on Lifespan in C. Elegans and Drosophila Nature. Sep, 2011 | Pubmed ID: 21938067 Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces Cerevisiae PLoS Genetics. Sep, 2011 | Pubmed ID: 21931558 Sir2 Deletion Prevents Lifespan Extension in 32 Long-lived Mutants Aging Cell. Dec, 2011 | Pubmed ID: 21902802 Trinations Aging Symposium Mechanisms of Ageing and Development. Jun-Jul, 2011 | Pubmed ID: 21771608 A Genomic Analysis of Chronological Longevity Factors in Budding Yeast Cell Cycle (Georgetown, Tex.). May, 2011 | Pubmed ID: 21447998 HIF-1 Modulates Longevity and Healthspan in a Temperature-dependent Manner Aging Cell. Apr, 2011 | Pubmed ID: 21241450 Quantitative Evidence for Early Life Fitness Defects from 32 Longevity-associated Alleles in Yeast Cell Cycle (Georgetown, Tex.). Jan, 2011 | Pubmed ID: 21191185 Hot Topics in Aging Research: Protein Translation and TOR Signaling, 2010 Aging Cell. Apr, 2011 | Pubmed ID: 21176090 Restoration of Senescent Human Diploid Fibroblasts by Modulation of the Extracellular Matrix Aging Cell. Feb, 2011 | Pubmed ID: 21108727 Regulation of MRNA Translation As a Conserved Mechanism of Longevity Control Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20886753 The Hypoxia-inducible Factor HIF-1 Functions As Both a Positive and Negative Modulator of Aging Biological Chemistry. Oct, 2010 | Pubmed ID: 20707608 A Role for SIRT1 in the Hypoxic Response Molecular Cell. Jun, 2010 | Pubmed ID: 20620950 Lessons on Longevity from Budding Yeast Nature. Mar, 2010 | Pubmed ID: 20336133 YODA: Software to Facilitate High-throughput Analysis of Chronological Life Span, Growth Rate, and Survival in Budding Yeast BMC Bioinformatics. 2010 | Pubmed ID: 20298554 Resveratrol and Rapamycin: Are They Anti-aging Drugs? BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Feb, 2010 | Pubmed ID: 20091754 Spermidine Surprise for a Long Life Nature Cell Biology. Nov, 2009 | Pubmed ID: 19884883 Cell Signaling. Aging is RSKy Business Science (New York, N.Y.). Oct, 2009 | Pubmed ID: 19797648 Attenuation of Age-related Metabolic Dysfunction in Mice with a Targeted Disruption of the Cbeta Subunit of Protein Kinase A The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Dec, 2009 | Pubmed ID: 19776218 Hot Topics in Aging Research: Protein Translation, 2009 Aging Cell. Dec, 2009 | Pubmed ID: 19747234 The Hypoxic Response and Aging Cell Cycle (Georgetown, Tex.). Aug, 2009 | Pubmed ID: 19633411 Ageing: A Midlife Longevity Drug? Nature. Jul, 2009 | Pubmed ID: 19606132 The TOR Pathway Comes of Age Biochimica Et Biophysica Acta. Oct, 2009 | Pubmed ID: 19539012 A Genomic Approach to Yeast Chronological Aging Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19521821 Histone H4 Lysine 16 Acetylation Regulates Cellular Lifespan Nature. Jun, 2009 | Pubmed ID: 19516333 Proteasomal Regulation of the Hypoxic Response Modulates Aging in C. Elegans Science (New York, N.Y.). May, 2009 | Pubmed ID: 19372390 A Molecular Mechanism of Chronological Aging in Yeast Cell Cycle (Georgetown, Tex.). Apr, 2009 | Pubmed ID: 19305133 Shortest-path Network Analysis is a Useful Approach Toward Identifying Genetic Determinants of Longevity PloS One. 2008 | Pubmed ID: 19030232 Protein Translation, 2008 Aging Cell. Dec, 2008 | Pubmed ID: 18782345 Cell Biology: A Molecular Age Barrier Nature. Aug, 2008 | Pubmed ID: 18685697 The Ongoing Saga of Sirtuins and Aging Cell Metabolism. Jul, 2008 | Pubmed ID: 18590685 Age- and Calorie-independent Life Span Extension from Dietary Restriction by Bacterial Deprivation in Caenorhabditis Elegans BMC Developmental Biology. 2008 | Pubmed ID: 18457595 The Biological Sciences Section Program at the 60th Annual Meeting of the Gerontological Society of America The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Apr, 2008 | Pubmed ID: 18426956 Yeast Life Span Extension by Depletion of 60s Ribosomal Subunits is Mediated by Gcn4 Cell. Apr, 2008 | Pubmed ID: 18423200 Quantitative Evidence for Conserved Longevity Pathways Between Divergent Eukaryotic Species Genome Research. Apr, 2008 | Pubmed ID: 18340043 Dietary Restriction Suppresses Proteotoxicity and Enhances Longevity by an Hsf-1-dependent Mechanism in Caenorhabditis Elegans Aging Cell. Jun, 2008 | Pubmed ID: 18331616 A Method for High-throughput Quantitative Analysis of Yeast Chronological Life Span The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2008 | Pubmed ID: 18314444 Dietary Restriction by Bacterial Deprivation Increases Life Span in Wild-derived Nematodes Experimental Gerontology. Mar, 2008 | Pubmed ID: 18083317 Single-gene Deletions That Restore Mating Competence to Diploid Yeast FEMS Yeast Research. Mar, 2008 | Pubmed ID: 17995956 Longevity Genomics Across Species Current Genomics. Apr, 2007 | Pubmed ID: 18660849 Protein Translation, 2007 Aging Cell. Dec, 2007 | Pubmed ID: 17941970 Molecular Basis of Ageing EMBO Reports. Oct, 2007 | Pubmed ID: 17823613 Does Resveratrol Activate Yeast Sir2 in Vivo? Aging Cell. Aug, 2007 | Pubmed ID: 17635418 Recent Developments in Yeast Aging PLoS Genetics. May, 2007 | Pubmed ID: 17530929 Sir2 and Calorie Restriction in Yeast: a Skeptical Perspective Ageing Research Reviews. Aug, 2007 | Pubmed ID: 17512264 The Sensitivity of Yeast Mutants to Oleic Acid Implicates the Peroxisome and Other Processes in Membrane Function Genetics. Jan, 2007 | Pubmed ID: 17151231 Genome-wide Identification of Conserved Longevity Genes in Yeast and Worms Mechanisms of Ageing and Development. Jan, 2007 | Pubmed ID: 17126379 Sirtuin-independent Effects of Nicotinamide on Lifespan Extension from Calorie Restriction in Yeast Aging Cell. Dec, 2006 | Pubmed ID: 17129213 Medicine: Grapes Versus Gluttony Nature. Nov, 2006 | Pubmed ID: 17086197 Lifespan Extension in Caenorhabditis Elegans by Complete Removal of Food Aging Cell. Dec, 2006 | Pubmed ID: 17081160 Genome-wide Approaches to Understanding Human Ageing Human Genomics. Jun, 2006 | Pubmed ID: 16848980 Comment on "HST2 Mediates SIR2-independent Life-span Extension by Calorie Restriction" Science (New York, N.Y.). Jun, 2006 | Pubmed ID: 16741098 Extension of Chronological Life Span in Yeast by Decreased TOR Pathway Signaling Genes & Development. Jan, 2006 | Pubmed ID: 16418483 Increased Life Span Due to Calorie Restriction in Respiratory-deficient Yeast PLoS Genetics. Nov, 2005 | Pubmed ID: 16311627 Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients Science (New York, N.Y.). Nov, 2005 | Pubmed ID: 16293764 The Enigmatic Role of Sir2 in Aging Cell. Nov, 2005 | Pubmed ID: 16286003 Genes Determining Yeast Replicative Life Span in a Long-lived Genetic Background Mechanisms of Ageing and Development. Apr, 2005 | Pubmed ID: 15722108 Substrate-specific Activation of Sirtuins by Resveratrol The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15684413 Large-scale Identification in Yeast of Conserved Ageing Genes Mechanisms of Ageing and Development. Jan, 2005 | Pubmed ID: 15610758 Aging-related Research in the "-omics" Age Science of Aging Knowledge Environment : SAGE KE. Oct, 2004 | Pubmed ID: 15498757 Sir2-independent Life Span Extension by Calorie Restriction in Yeast PLoS Biology. Sep, 2004 | Pubmed ID: 15328540 Saccharomyces Cerevisiae SSD1-V Confers Longevity by a Sir2p-independent Mechanism Genetics. Apr, 2004 | Pubmed ID: 15126388 High Osmolarity Extends Life Span in Saccharomyces Cerevisiae by a Mechanism Related to Calorie Restriction Molecular and Cellular Biology. Nov, 2002 | Pubmed ID: 12391171 Calorie Restriction Extends Saccharomyces Cerevisiae Lifespan by Increasing Respiration Nature. Jul, 2002 | Pubmed ID: 12124627 AGEID: a Database of Aging Genes and Interventions Mechanisms of Ageing and Development. Apr, 2002 | Pubmed ID: 12044961 Mutations in Saccharomyces Cerevisiae Gene SIR2 Can Have Differential Effects on in Vivo Silencing Phenotypes and in Vitro Histone Deacetylation Activity Molecular Biology of the Cell. Apr, 2002 | Pubmed ID: 11950950 Saccharomyces Cerevisiae MPT5 and SSD1 Function in Parallel Pathways to Promote Cell Wall Integrity Genetics. Jan, 2002 | Pubmed ID: 11805047 Arınma ve Caenorhabditis elegans Ekstrasellüler Veziküllerin Analizi Joshua C. Russell1, Nadia Postupna1, Alexandra Golubeva1, C. Dirk Keene1, Matt Kaeberlein1 1Department of Pathology, University of Washington JoVE 60596 Biology Geliştirici Maya replikatif Ömrü Ölçüm Kristan K. Steffen1, Brian K. Kennedy1, Matt Kaeberlein2 1Department of Biochemistry, University of Washington, 2Department of Pathology, University of Washington JoVE 1209 Biology Ölçme Caenorhabditis elegans Katı Medya Ömrü George L. Sutphin1,2, Matt Kaeberlein1 1Department of Pathology, University of Washington, 2Molecular and Cellular Biology Program, University of Washington JoVE 1152 Biology Yaşlı Hücre akıbet tarafından Maya Kronolojik Ömrü miktarının Christopher Murakami1, Matt Kaeberlein1 1Department of Pathology, University of Washington JoVE 1156 Biology
Arınma ve Caenorhabditis elegans Ekstrasellüler Veziküllerin Analizi Joshua C. Russell1, Nadia Postupna1, Alexandra Golubeva1, C. Dirk Keene1, Matt Kaeberlein1 1Department of Pathology, University of Washington JoVE 60596 Biology
Geliştirici Maya replikatif Ömrü Ölçüm Kristan K. Steffen1, Brian K. Kennedy1, Matt Kaeberlein2 1Department of Biochemistry, University of Washington, 2Department of Pathology, University of Washington JoVE 1209 Biology
Ölçme Caenorhabditis elegans Katı Medya Ömrü George L. Sutphin1,2, Matt Kaeberlein1 1Department of Pathology, University of Washington, 2Molecular and Cellular Biology Program, University of Washington JoVE 1152 Biology
Yaşlı Hücre akıbet tarafından Maya Kronolojik Ömrü miktarının Christopher Murakami1, Matt Kaeberlein1 1Department of Pathology, University of Washington JoVE 1156 Biology
