Matthew G. Holt VIB-KU Leuven Center for Brain and Disease Research VIB Biography Publications Institution JoVE Articles Matthew G. Holt Matthew Holt is based at the VIB-KU Leuven Center for Brain and Disease Research. He originally trained as a biochemist at the University of Liverpool, before pursuing research into the physiology of synaptic transmission at the MRC Laboratory for Molecular Biology, obtaining his Ph.D. degree from the University of Cambridge. He followed this with post-doctoral training in the lab of Reinhard Jahn at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany. Since 2012, he has been an independent VIB group leader and professor at the KU Leuven, working on the role of astrocyte-neuron interactions in control of CNS function. Publications Widespread Transduction of Astrocytes and Neurons in the Mouse Central Nervous System After Systemic Delivery of a Self-complementary AAV-PHP.B Vector Gene Therapy. 04, 2018 | Pubmed ID: 29523880 Satnav for Cells: Destination Membrane Fusion Cell Calcium. 12, 2017 | Pubmed ID: 29129204 An Immunoaffinity-based Method for Isolating Ultrapure Adult Astrocytes Based on ATP1B2 Targeting by the ACSA-2 Antibody The Journal of Biological Chemistry. 05, 2017 | Pubmed ID: 28373281 Production, Purification, and Quality Control for Adeno-associated Virus-based Vectors Shelly Fripont*1,2, Catherine Marneffe*1,2, Marika Marino*1,2, Melvin Y. Rincon1,2, Matthew G. Holt1,2,3 1VIB-KU Leuven Center for Brain and Disease Research, 2Department of Neuroscience, KU Leuven, 3Leuven Brain Institute JoVE 58960 Neuroscience
Production, Purification, and Quality Control for Adeno-associated Virus-based Vectors Shelly Fripont*1,2, Catherine Marneffe*1,2, Marika Marino*1,2, Melvin Y. Rincon1,2, Matthew G. Holt1,2,3 1VIB-KU Leuven Center for Brain and Disease Research, 2Department of Neuroscience, KU Leuven, 3Leuven Brain Institute JoVE 58960 Neuroscience
