Matthew J. Gaffrey Integrative Omics, Biological Sciences Division Pacific Northwest National Laboratory Biography Publications Institution JoVE Articles Matthew J. Gaffrey has not added a biography. If you are Matthew J. Gaffrey and would like to personalize this page please email our Author Liaison for assistance. Publications Stoichiometric Thiol Redox Proteomics for Quantifying Cellular Responses to Perturbations Antioxidants (Basel, Switzerland). Mar, 2021 | Pubmed ID: 33807006 Enhancement of Polyhydroxyalkanoate Production by Co-feeding Lignin Derivatives with Glycerol in Pseudomonas Putida KT2440 Biotechnology for Biofuels. Jan, 2021 | Pubmed ID: 33413621 Characterization of Cellular Oxidative Stress Response by Stoichiometric Redox Proteomics American Journal of Physiology. Cell Physiology. 02, 2021 | Pubmed ID: 33264075 Protein Thiol Oxidation in the Rat Lung Following E-cigarette Exposure Redox Biology. Oct, 2020 | Pubmed ID: 33080441 Stochiometric Quantification of the Thiol Redox Proteome of Macrophages Reveals Subcellular Compartmentalization and Susceptibility to Oxidative Perturbations Redox Biology. Sep, 2020 | Pubmed ID: 32750668 Automated Coupling of Nanodroplet Sample Preparation with Liquid Chromatography-Mass Spectrometry for High-Throughput Single-Cell Proteomics Analytical Chemistry. 08, 2020 | Pubmed ID: 32639140 Block Design with Common Reference Samples Enables Robust Large-Scale Label-Free Quantitative Proteome Profiling Journal of Proteome Research. 07, 2020 | Pubmed ID: 32407631 Accurate Identification of Deamidation and Citrullination from Global Shotgun Proteomics Data Using a Dual-Search Delta Score Strategy Journal of Proteome Research. 04, 2020 | Pubmed ID: 32175737 Evaluation of the Cytotoxic and Cellular Proteome Impacts of Food-grade TiO (E171) Using Simulated Gastrointestinal Digestions and a Tri-culture Small Intestinal Epithelial Model NanoImpact. Jan, 2020 | Pubmed ID: 32133427 A Proteome-wide Assessment of the Oxidative Stress Paradigm for Metal and Metal-oxide Nanomaterials in Human Macrophages NanoImpact. Jan, 2020 | Pubmed ID: 32133426 Comprehensive Detection of Single Amino Acid Variants and Evaluation of Their Deleterious Potential in a PANC-1 Cell Line Journal of Proteome Research. 04, 2020 | Pubmed ID: 32058723 Rosette Core Fungal Resistance in Arabidopsis Thaliana Planta. Dec, 2019 | Pubmed ID: 31529398 Discovery of Potential Pathways for Biological Conversion of Poplar Wood into Lipids by Co-fermentation of Strains Biotechnology for Biofuels. 2019 | Pubmed ID: 30923568 Improving Mitochondrial Function with SS-31 Reverses Age-related Redox Stress and Improves Exercise Tolerance in Aged Mice Free Radical Biology & Medicine. 04, 2019 | Pubmed ID: 30597195 Carrier-Assisted Single-Tube Processing Approach for Targeted Proteomics Analysis of Low Numbers of Mammalian Cells Analytical Chemistry. 01, 2019 | Pubmed ID: 30557009 Reference Genes for Accurate Normalization of Gene Expression in Wood-decomposing Fungi Fungal Genetics and Biology : FG & B. 02, 2019 | Pubmed ID: 30529285 All That is Silver is Not Toxic: Silver Ion and Particle Kinetics Reveals the Role of Silver Ion Aging and Dosimetry on the Toxicity of Silver Nanoparticles Particle and Fibre Toxicology. 12, 2018 | Pubmed ID: 30518385 Facile Carrier-assisted Targeted Mass Spectrometric Approach for Proteomic Analysis of Low Numbers of Mammalian Cells Communications Biology. 2018 | Pubmed ID: 30271983 Mass Spectrometry-based Proteomics for System-level Characterization of Biological Responses to Engineered Nanomaterials Analytical and Bioanalytical Chemistry. Sep, 2018 | Pubmed ID: 29947897 Fatiguing Contractions Increase Protein S-glutathionylation Occupancy in Mouse Skeletal Muscle Redox Biology. 07, 2018 | Pubmed ID: 29857311 Fluctuation Localization Imaging-based Fluorescence in Situ Hybridization (fliFISH) for Accurate Detection and Counting of RNA Copies in Single Cells Nucleic Acids Research. 01, 2018 | Pubmed ID: 29040675 Quantitative Proteomic Characterization of Redox-dependent Post-translational Modifications on Protein Cysteines Molecular BioSystems. May, 2017 | Pubmed ID: 28357434 Cells Respond to Distinct Nanoparticle Properties with Multiple Strategies As Revealed by Single-Cell RNA-Seq ACS Nano. Nov, 2016 | Pubmed ID: 27788331 Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-Dependent Regulation of Macrophage Function During Nanoparticle-Induced Oxidative Stress ACS Nano. Jan, 2016 | Pubmed ID: 26700264 Sensitive Targeted Quantification of ERK Phosphorylation Dynamics and Stoichiometry in Human Cells Without Affinity Enrichment Analytical Chemistry. Jan, 2015 | Pubmed ID: 25517423 Proteome-wide Light/dark Modulation of Thiol Oxidation in Cyanobacteria Revealed by Quantitative Site-specific Redox Proteomics Molecular & Cellular Proteomics : MCP. Dec, 2014 | Pubmed ID: 25118246 Resin-assisted Enrichment of Thiols As a General Strategy for Proteomic Profiling of Cysteine-based Reversible Modifications Nature Protocols. Jan, 2014 | Pubmed ID: 24336471 Proteomic Identification and Quantification of S-glutathionylation in Mouse Macrophages Using Resin-assisted Enrichment and Isobaric Labeling Free Radical Biology & Medicine. Feb, 2014 | Pubmed ID: 24333276 Late-life Restoration of Mitochondrial Function Reverses Cardiac Dysfunction in Old Mice ELife. | Pubmed ID: 32648542 Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation Matthew J. Gaffrey1, Nicholas J. Day1, Xiaolu Li2, Wei-Jun Qian1 1Integrative Omics, Biological Sciences Division, Pacific Northwest National Laboratory, 2Bioproducts Sciences and Engineering Laboratory, Department of Biological Systems Engineering, Washington State University JoVE 62671 Biochemistry
Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation Matthew J. Gaffrey1, Nicholas J. Day1, Xiaolu Li2, Wei-Jun Qian1 1Integrative Omics, Biological Sciences Division, Pacific Northwest National Laboratory, 2Bioproducts Sciences and Engineering Laboratory, Department of Biological Systems Engineering, Washington State University JoVE 62671 Biochemistry