Matthew Merritt

Publications

• A General Chemical Shift Decomposition Method for Hyperpolarized (13) C Metabolite Magnetic Resonance Imaging
  Magnetic Resonance in Chemistry : MRC. Apr, 2016  |   Pubmed ID: 27060361
• Mitochondrial Metabolism Mediates Oxidative Stress and Inflammation in Fatty Liver
  The Journal of Clinical Investigation. Apr, 2016  |   Pubmed ID: 27035816
• Multiband Spectral-spatial RF Excitation for Hyperpolarized [2-(13) C]dihydroxyacetone (13) C-MR Metabolism Studies
  Magnetic Resonance in Medicine. Mar, 2016  |   Pubmed ID: 27017966
• Metabolism of Hyperpolarized [1-(13) C]pyruvate Through Alternate Pathways in Rat Liver
  NMR in Biomedicine. Apr, 2016  |   Pubmed ID: 26836042
• Mitochondrial Metabolism Mediates Oxidative Stress and Inflammation in Fatty Liver
  The Journal of Clinical Investigation. Dec, 2015  |   Pubmed ID: 26571396
• Production of Hyperpolarized (13)CO2 from [1-(13)C]pyruvate in Perfused Liver Does Reflect Total Anaplerosis but is Not a Reliable Biomarker of Glucose Production
  Metabolomics : Official Journal of the Metabolomic Society. Oct, 2015  |   Pubmed ID: 26543443
• Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors
  Cancer Research. Nov, 2015  |   Pubmed ID: 26420214
• Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs
  Methods in Enzymology. 2015  |   Pubmed ID: 26358902
• Hyperpolarized 13C NMR Detects Rapid Drug-induced Changes in Cardiac Metabolism
  Magnetic Resonance in Medicine. Aug, 2015  |   Pubmed ID: 25168480
• Development and Performance of a 129-GHz Dynamic Nuclear Polarizer in an Ultra-wide Bore Superconducting Magnet
  Magma (New York, N.Y.). Apr, 2015  |   Pubmed ID: 25120071
• Glutamine Oxidation Maintains the TCA Cycle and Cell Survival During Impaired Mitochondrial Pyruvate Transport
  Molecular Cell. Nov, 2014  |   Pubmed ID: 25458842
• Hyperpolarized Magnetic Resonance As a Sensitive Detector of Metabolic Function
  Biochemistry. Dec, 2014  |   Pubmed ID: 25369537
• Real-time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized [2-13C]dihydroxyacetone
  The Journal of Biological Chemistry. Dec, 2014  |   Pubmed ID: 25352600
• Propionate Stimulates Pyruvate Oxidation in the Presence of Acetate
  American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2014  |   Pubmed ID: 25320331
• Metabolic Characteristics of Human Hearts Preserved for 12 Hours by Static Storage, Antegrade Perfusion, or Retrograde Coronary Sinus Perfusion
  The Journal of Thoracic and Cardiovascular Surgery. Nov, 2014  |   Pubmed ID: 24642559
• Simultaneous Steady-state and Dynamic 13C NMR Can Differentiate Alternative Routes of Pyruvate Metabolism in Living Cancer Cells
  The Journal of Biological Chemistry. Feb, 2014  |   Pubmed ID: 24415759
• Electron Spin Resonance Studies of Trityl OX063 at a Concentration Optimal for DNP
  Physical Chemistry Chemical Physics : PCCP. Jun, 2013  |   Pubmed ID: 23676994
• Influence of Deuteration in the Glassing Matrix on 13C Dynamic Nuclear Polarization
  Physical Chemistry Chemical Physics : PCCP. May, 2013  |   Pubmed ID: 23552448
• Dissolution DNP-NMR Spectroscopy Using Galvinoxyl As a Polarizing Agent
  Journal of Magnetic Resonance (San Diego, Calif. : 1997). Feb, 2013  |   Pubmed ID: 23246650
• The Efficiency of DPPH As a Polarising Agent for DNP-NMR Spectroscopy
  RSC Advances. Jan, 2012  |   Pubmed ID: 23205273
• Impact of Gd3+ on DNP of [1-13C]pyruvate Doped with Trityl OX063, BDPA, or 4-oxo-TEMPO
  The Journal of Physical Chemistry. A. May, 2012  |   Pubmed ID: 22571288
• Comparison of Kinetic Models for Analysis of Pyruvate-to-lactate Exchange by Hyperpolarized 13 C NMR
  NMR in Biomedicine. Nov, 2012  |   Pubmed ID: 22451442
• Nanoparticle-based PARACEST Agents: the Quenching Effect of Silica Nanoparticles on the CEST Signal from Surface-conjugated Chelates
  Contrast Media & Molecular Imaging. Jan-Feb, 2012  |   Pubmed ID: 22344876
• Production and NMR Characterization of Hyperpolarized (107,109)Ag Complexes
  Angewandte Chemie (International Ed. in English). Jan, 2012  |   Pubmed ID: 21998014
• Glucose is an Ineffective Substrate for Preservation of Machine Perfused Donor Hearts
  The Journal of Surgical Research. Apr, 2012  |   Pubmed ID: 21816432
• Flux Through Hepatic Pyruvate Carboxylase and Phosphoenolpyruvate Carboxykinase Detected by Hyperpolarized 13C Magnetic Resonance
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011  |   Pubmed ID: 22065779
• Differences in Regional Myocardial Perfusion, Metabolism, MVO2, and Edema After Coronary Sinus Machine Perfusion Preservation of Canine Hearts
  ASAIO Journal (American Society for Artificial Internal Organs : 1992). Nov-Dec, 2011  |   Pubmed ID: 22036719
• Transfer of Hyperpolarization from Long T1 Storage Nuclei to Short T1 Neighbors Using FLOPSY-8
  Journal of Magnetic Resonance (San Diego, Calif. : 1997). Dec, 2011  |   Pubmed ID: 21974998
• BDPA: an Efficient Polarizing Agent for Fast Dissolution Dynamic Nuclear Polarization NMR Spectroscopy
  Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2011  |   Pubmed ID: 21919088
• Could 13C MRI Assist Clinical Decision-making for Patients with Heart Disease?
  NMR in Biomedicine. Oct, 2011  |   Pubmed ID: 21608058
• T2 Exchange Agents: a New Class of Paramagnetic MRI Contrast Agent That Shortens Water T2 by Chemical Exchange Rather Than Relaxation
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2011  |   Pubmed ID: 21608031
• DNP by Thermal Mixing Under Optimized Conditions Yields >60,000-fold Enhancement of 89Y NMR Signal
  Journal of the American Chemical Society. Jun, 2011  |   Pubmed ID: 21539398
• 1H Magic Angle Spinning Magnetic Resonance Spectroscopy for Monitoring Machine-perfused Canine Donor Heart Preservation Prior to Transplantation
  The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2011  |   Pubmed ID: 21429765
• The Effect of 13C Enrichment in the Glassing Matrix on Dynamic Nuclear Polarization of [1-13C]pyruvate
  Physics in Medicine and Biology. Mar, 2011  |   Pubmed ID: 21285486
• Competition of Pyruvate with Physiological Substrates for Oxidation by the Heart: Implications for Studies with Hyperpolarized [1-13C]pyruvate
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2010  |   Pubmed ID: 20207817
• Hyperpolarized 89Y Complexes As PH Sensitive NMR Probes
  Journal of the American Chemical Society. Feb, 2010  |   Pubmed ID: 20102196
• Inhibition of Carbohydrate Oxidation During the First Minute of Reperfusion After Brief Ischemia: NMR Detection of Hyperpolarized 13CO2 and H13CO3-
  Magnetic Resonance in Medicine. Nov, 2008  |   Pubmed ID: 18956454
• Alterations in Hepatic Glucose and Energy Metabolism As a Result of Calorie and Carbohydrate Restriction
  Hepatology (Baltimore, Md.). Nov, 2008  |   Pubmed ID: 18925642
• Sources of Hepatic Glucose Production by 2H2O Ingestion and Bayesian Analysis of 2H Glucuronide Enrichment
  Magnetic Resonance in Medicine. Sep, 2008  |   Pubmed ID: 18727053
• Partial Resistance to Peroxisome Proliferator-activated Receptor-alpha Agonists in ZDF Rats is Associated with Defective Hepatic Mitochondrial Metabolism
  Diabetes. Aug, 2008  |   Pubmed ID: 18469201
• Perfusion Preservation Versus Static Preservation for Cardiac Transplantation: Effects on Myocardial Function and Metabolism
  The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jan, 2008  |   Pubmed ID: 18187093
• Hyperpolarized 13C Allows a Direct Measure of Flux Through a Single Enzyme-catalyzed Step by NMR
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007  |   Pubmed ID: 18056642
• Dipolar Cross-relaxation Modulates Signal Amplitudes in the (1)H NMR Spectrum of Hyperpolarized [(13)C]formate
  Journal of Magnetic Resonance (San Diego, Calif. : 1997). Dec, 2007  |   Pubmed ID: 17945520
• Hyperpolarized (89)Y Offers the Potential of Direct Imaging of Metal Ions in Biological Systems by Magnetic Resonance
  Journal of the American Chemical Society. Oct, 2007  |   Pubmed ID: 17927188
• Benefits of Perfusion Preservation in Canine Hearts Stored for Short Intervals
  The Journal of Surgical Research. Jun, 2007  |   Pubmed ID: 17509270
• Hepatic UDP-glucose 13C Isotopomers from [U-13C]glucose: a Simple Analysis by 13C NMR of Urinary Menthol Glucuronide
  Magnetic Resonance in Medicine. Nov, 2006  |   Pubmed ID: 17036288
• Linkage Between Cellular Communications, Energy Utilization, and Proliferation in Metastatic Neuroendocrine Cancers
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006  |   Pubmed ID: 16895983
• Storage and Oxidation of Long-chain Fatty Acids in the C57/BL6 Mouse Heart As Measured by NMR Spectroscopy
  FEBS Letters. Jul, 2006  |   Pubmed ID: 16831433
• Novel 1H NMR Approach to Quantitative Tissue Oximetry Using Hexamethyldisiloxane
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Apr, 2006  |   Pubmed ID: 16506157
• Adiabatic JHSQC for 13C Isotopomer Analysis
  Magnetic Resonance in Chemistry : MRC. Apr, 2006  |   Pubmed ID: 16408316
• Effects of Insulin and Cytosolic Redox State on Glucose Production Pathways in the Isolated Perfused Mouse Liver Measured by Integrated 2H and 13C NMR
  The Biochemical Journal. Mar, 2006  |   Pubmed ID: 16288601
• A New Class of Macrocyclic Lanthanide Complexes for Cell Labeling and Magnetic Resonance Imaging Applications
  Journal of the American Chemical Society. Nov, 2005  |   Pubmed ID: 16287307
• Comparison of [3,4-13C2]glucose to [6,6-2H2]glucose As a Tracer for Glucose Turnover by Nuclear Magnetic Resonance
  Magnetic Resonance in Medicine. Jun, 2005  |   Pubmed ID: 15906303
• Numerical Solution of the Bloch Equations Provides Insights into the Optimum Design of PARACEST Agents for MRI
  Magnetic Resonance in Medicine. Apr, 2005  |   Pubmed ID: 15799055
• Effect of Murine Strain on Metabolic Pathways of Glucose Production After Brief or Prolonged Fasting
  American Journal of Physiology. Endocrinology and Metabolism. Jul, 2005  |   Pubmed ID: 15797985
• Differing Mechanisms of Hepatic Glucose Overproduction in Triiodothyronine-treated Rats Vs. Zucker Diabetic Fatty Rats by NMR Analysis of Plasma Glucose
  American Journal of Physiology. Endocrinology and Metabolism. Apr, 2005  |   Pubmed ID: 15562253
• Impaired Tricarboxylic Acid Cycle Activity in Mouse Livers Lacking Cytosolic Phosphoenolpyruvate Carboxykinase
  The Journal of Biological Chemistry. Nov, 2004  |   Pubmed ID: 15347677
• Glucose Production Pathways by 2H and 13C NMR in Patients with HIV-associated Lipoatrophy
  Magnetic Resonance in Medicine. Apr, 2004  |   Pubmed ID: 15065235
• Glucose Production, Gluconeogenesis, and Hepatic Tricarboxylic Acid Cycle Fluxes Measured by Nuclear Magnetic Resonance Analysis of a Single Glucose Derivative
  Analytical Biochemistry. Apr, 2004  |   Pubmed ID: 15051530
• Silencing of Phosphonate-gadolinium Magnetic Resonance Imaging Contrast by Hydroxyapatite Binding
  Investigative Radiology. Dec, 2003  |   Pubmed ID: 14627892
• PARACEST Agents: Modulating MRI Contrast Via Water Proton Exchange
  Accounts of Chemical Research. Oct, 2003  |   Pubmed ID: 14567712
• Sources of Plasma Glucose by Automated Bayesian Analysis of 2H NMR Spectra
  Magnetic Resonance in Medicine. Oct, 2003  |   Pubmed ID: 14523948
• Noninvasive Evaluation of Liver Metabolism by 2H and 13C NMR Isotopomer Analysis of Human Urine
  Analytical Biochemistry. Jan, 2003  |   Pubmed ID: 12531210