Max S. Wicha Department of Internal Medicine University of Michigan Biography Publications Institution JoVE Articles Max S. Wicha has not added a biography. If you are Max S. Wicha and would like to personalize this page please email our Author Liaison for assistance. Publications Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24- Subpopulations of Breast Cancer Cells PloS One. 2013 | Pubmed ID: 24376586 Sensitive Capture of Circulating Tumour Cells by Functionalized Graphene Oxide Nanosheets Nature Nanotechnology. Oct, 2013 | Pubmed ID: 24077027 The Thyroid Cancer PAX8-PPARG Fusion Protein Activates Wnt/TCF-responsive Cells That Have a Transformed Phenotype Endocrine-related Cancer. Oct, 2013 | Pubmed ID: 24025583 Cytokine-induced Killer (CIK) Cells Bound with Anti-CD3/anti-CD133 Bispecific Antibodies Target CD133(high) Cancer Stem Cells in Vitro and in Vivo Clinical Immunology (Orlando, Fla.). Oct, 2013 | Pubmed ID: 23994769 Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics Cancer Research. Sep, 2013 | Pubmed ID: 23832665 HER2 and Breast Cancer Stem Cells: More Than Meets the Eye Cancer Research. Jun, 2013 | Pubmed ID: 23740771 Notch Pathway Activity Identifies Cells with Cancer Stem Cell-like Properties and Correlates with Worse Survival in Lung Adenocarcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2013 | Pubmed ID: 23444212 HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab Cancer Research. Mar, 2013 | Pubmed ID: 23442322 B4 Androgen Ablation: Attacking the Prostate Cancer Stem Cell The Journal of Clinical Investigation. Feb, 2013 | Pubmed ID: 23348735 Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2013 | Pubmed ID: 23340294 Breast Cancer Stem Cells: We've Got Them Surrounded Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2013 | Pubmed ID: 23251003 Point: Cancer Stem Cells--the Evidence Accumulates Clinical Chemistry. Jan, 2013 | Pubmed ID: 23143328 Targeting Cancer Stem Cells Via Dendritic-cell Vaccination Oncoimmunology. Nov, 2012 | Pubmed ID: 23243607 Migratory Gene Expression Signature Predicts Poor Patient Outcome: Are Cancer Stem Cells to Blame? Breast Cancer Research : BCR. Nov, 2012 | Pubmed ID: 23153392 HER2-associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-negative Breast Cancer Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2012 | Pubmed ID: 23091114 Lin28 and HER2: Two Stem Cell Regulators Conspire to Drive Aggressive Breast Cancer Cell Cycle (Georgetown, Tex.). Aug, 2012 | Pubmed ID: 22833047 Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population Molecular Cell. Aug, 2012 | Pubmed ID: 22819326 MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells PLoS Genetics. 2012 | Pubmed ID: 22685420 PSA Lo and Behold: Prostate Cancer Stem Cells Cell Stem Cell. May, 2012 | Pubmed ID: 22560068 Cancer Stem Cell Vaccination Confers Significant Antitumor Immunity Cancer Research. Apr, 2012 | Pubmed ID: 22473314 Antiangiogenic Agents: Fueling Cancer's Hypoxic Roots Cell Cycle (Georgetown, Tex.). Apr, 2012 | Pubmed ID: 22421155 Role of MicroRNAs in the Regulation of Breast Cancer Stem Cells Journal of Mammary Gland Biology and Neoplasia. Mar, 2012 | Pubmed ID: 22331423 Antiangiogenic Agents Increase Breast Cancer Stem Cells Via the Generation of Tumor Hypoxia Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308314 Expression of Aldehyde Dehydrogenase and CD133 Defines Ovarian Cancer Stem Cells International Journal of Cancer. Journal International Du Cancer. Jan, 2012 | Pubmed ID: 21480217 Clinical Trial Design for Testing the Stem Cell Model for the Prevention and Treatment of Cancer Cancers. 2011 | Pubmed ID: 24212828 Breast Cancer Stem Cells, Cytokine Networks, and the Tumor Microenvironment The Journal of Clinical Investigation. Oct, 2011 | Pubmed ID: 21965337 Inflammation and Autophagy Conspire to Promote Tumor Growth Cell Cycle (Georgetown, Tex.). Aug, 2011 | Pubmed ID: 21829104 Ablation of Breast Cancer Stem Cells with Radiation Translational Oncology. Aug, 2011 | Pubmed ID: 21804918 Regulation of Cancer Stem Cells by Cytokine Networks: Attacking Cancer's Inflammatory Roots Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2011 | Pubmed ID: 21685479 Aldehyde Dehydrogenase in Combination with CD133 Defines Angiogenic Ovarian Cancer Stem Cells That Portend Poor Patient Survival Cancer Research. Jun, 2011 | Pubmed ID: 21498635 Circulating Tumor Cells: Not All Detected Cells Are Bad and Not All Bad Cells Are Detected Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2011 | Pubmed ID: 21422428 Stemming a Tumor with a Little MiR Nature Medicine. Feb, 2011 | Pubmed ID: 21297608 Implications of Cancer Stem Cell Theory for Cancer Chemoprevention by Natural Dietary Compounds The Journal of Nutritional Biochemistry. Sep, 2011 | Pubmed ID: 21295962 Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells Through Cytokine Networks Cancer Research. Jan, 2011 | Pubmed ID: 21224357 Endothelial Cell-initiated Signaling Promotes the Survival and Self-renewal of Cancer Stem Cells Cancer Research. Dec, 2010 | Pubmed ID: 21098716 Stem Cells in Normal Development and Cancer Progress in Molecular Biology and Translational Science. 2010 | Pubmed ID: 21075331 Targeting Breast Cancer Stem Cells Molecular Oncology. Oct, 2010 | Pubmed ID: 20599450 Breast Tumors: of Mice and Women Breast Cancer Research : BCR. 2010 | Pubmed ID: 20550730 Targeting Breast Cancer Stem Cells Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2010 | Pubmed ID: 20498387 Cancer Stem Cells: Nature Versus Nurture Nature Cell Biology. May, 2010 | Pubmed ID: 20418873 Sulforaphane, a Dietary Component of Broccoli/broccoli Sprouts, Inhibits Breast Cancer Stem Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2010 | Pubmed ID: 20388854 頭頸部の扁平上皮がん幹細胞とアルデヒド脱水素酵素の単一マーカー同定。 Head & Neck. Sep, 2010 | Pubmed ID: 20073073 CXCR1 Blockade Selectively Targets Human Breast Cancer Stem Cells in Vitro and in Xenografts The Journal of Clinical Investigation. Feb, 2010 | Pubmed ID: 20051626 Aldehyde Dehydrogenase 1-positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2010 | Pubmed ID: 20028757 Targeting Breast Stem Cells with the Cancer Preventive Compounds Curcumin and Piperine Breast Cancer Research and Treatment. Aug, 2010 | Pubmed ID: 19898931 Targeting Breast Cancer Stem Cells Breast (Edinburgh, Scotland). Oct, 2009 | Pubmed ID: 19914544 Identification of Single Chain Antibodies to Breast Cancer Stem Cells Using Phage Display Biotechnology Progress. Nov-Dec, 2009 | Pubmed ID: 19899107 An Embryonic Stem Cell-like Signature Identifies Poorly Differentiated Lung Adenocarcinoma but Not Squamous Cell Carcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2009 | Pubmed ID: 19808871 Retinoid Signaling Regulates Breast Cancer Stem Cell Differentiation Cell Cycle (Georgetown, Tex.). Oct, 2009 | Pubmed ID: 19806016 Development of 'synthetic Lethal' Strategies to Target BRCA1-deficient Breast Cancer Breast Cancer Research : BCR. 2009 | Pubmed ID: 19804613 Getting to the Root of BRCA1-deficient Breast Cancer Cell Stem Cell. Sep, 2009 | Pubmed ID: 19733528 Regulation of Mammary Stem/progenitor Cells by PTEN/Akt/beta-catenin Signaling PLoS Biology. Jun, 2009 | Pubmed ID: 19492080 Aldehyde Dehydrogenase 1 is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation During Colon Tumorigenesis Cancer Research. Apr, 2009 | Pubmed ID: 19336570 HER-2, Notch, and Breast Cancer Stem Cells: Targeting an Axis of Evil Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2009 | Pubmed ID: 19276254 Tumor-initiating Cells and Treatment Resistance: How Goes the War? Journal of Mammary Gland Biology and Neoplasia. Mar, 2009 | Pubmed ID: 19238526 Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature Cancer Research. Feb, 2009 | Pubmed ID: 19190339 Mammary Epithelial-specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/progenitor Cells Cancer Research. Jan, 2009 | Pubmed ID: 19147559 [Stem Cells and Epithelial Cancers: the Example of Breast Cancer] Annales De Pathologie. Nov, 2008 | Pubmed ID: 18984292 Colon Cancer Stem Cells: Implications for Prevention and Therapy Trends in Molecular Medicine. Nov, 2008 | Pubmed ID: 18929507 Cancer Stem Cells in Breast: Current Opinion and Future Challenges Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 2008 | Pubmed ID: 18544962 Implications of the Cancer Stem-cell Hypothesis for Breast Cancer Prevention and Therapy Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2008 | Pubmed ID: 18539959 Cancer Stem Cells: a Step Toward the Cure Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2008 | Pubmed ID: 18539956 Cancer Stem Cell Heterogeneity in Hereditary Breast Cancer Breast Cancer Research : BCR. 2008 | Pubmed ID: 18423071 BRCA1 Regulates Human Mammary Stem/progenitor Cell Fate Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18230721 ALDH1 is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome Cell Stem Cell. Nov, 2007 | Pubmed ID: 18371393 [The Cancer Stem Cell: the Breast Cancer Driver] Médecine Sciences : M/S. Dec, 2007 | Pubmed ID: 18154716 Cancer Stem Cells: Implications for Cancer Treatment and Prevention Cancer Journal (Sudbury, Mass.). Sep-Oct, 2007 | Pubmed ID: 17921723 Selective Targeting of Cancer Stem Cells: a New Concept in Cancer Therapeutics BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 2007 | Pubmed ID: 17896836 Breast Cancer Stem Cells-research Opportunities Utilizing Mathematical Modeling Stem Cell Reviews. Jun, 2007 | Pubmed ID: 17873350 Breast Cancer Stem Cells: the Other Side of the Story Stem Cell Reviews. Jun, 2007 | Pubmed ID: 17873342 Mammary Stem Cell Number As a Determinate of Breast Cancer Risk Breast Cancer Research : BCR. 2007 | Pubmed ID: 17688678 Cancer Stem Cells and Metastasis: Lethal Seeds Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2006 | Pubmed ID: 17020960 Identification of Murine Mammary Stem Cells: Implications for Studies of Mammary Development and Carcinogenesis Breast Cancer Research : BCR. 2006 | Pubmed ID: 16934104 Hedgehog Signaling and Bmi-1 Regulate Self-renewal of Normal and Malignant Human Mammary Stem Cells Cancer Research. Jun, 2006 | Pubmed ID: 16778178 Cancer Stem Cells: an Old Idea--a Paradigm Shift Cancer Research. Feb, 2006 | Pubmed ID: 16488983 Stem Cells in Mammary Development and Carcinogenesis: Implications for Prevention and Treatment Stem Cell Reviews. 2005 | Pubmed ID: 17142857 Mammary Stem Cells, Self-renewal Pathways, and Carcinogenesis Breast Cancer Research : BCR. 2005 | Pubmed ID: 15987436 Survival of Mammary Stem Cells in Suspension Culture: Implications for Stem Cell Biology and Neoplasia Journal of Mammary Gland Biology and Neoplasia. Jan, 2005 | Pubmed ID: 15886888 Role of Notch Signaling in Cell-fate Determination of Human Mammary Stem/progenitor Cells Breast Cancer Research : BCR. 2004 | Pubmed ID: 15535842 New Organizational and Funds Flow Models for an Academic Cancer Center Academic Medicine : Journal of the Association of American Medical Colleges. Jul, 2004 | Pubmed ID: 15234911 Breast Cancer, Stem/progenitor Cells and the Estrogen Receptor Trends in Endocrinology and Metabolism: TEM. Jul, 2004 | Pubmed ID: 15223047 Stem Cells in Normal Breast Development and Breast Cancer Cell Proliferation. Oct, 2003 | Pubmed ID: 14521516 In Vitro Propagation and Transcriptional Profiling of Human Mammary Stem/progenitor Cells Genes & Development. May, 2003 | Pubmed ID: 12756227 Prospective Identification of Tumorigenic Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12629218 黒色腫と扁平上癌幹細胞を用いた新規樹状細胞ワクチンの生成 Qiao Li1, Lin Lu1, Huimin Tao1, Carolyn Xue1, Seagal Teitz-Tennenbaum2, John H. Owen3, Jeffrey S Moyer3, Mark E.P. Prince3, Alfred E. Chang1, Max S. Wicha2 1Department of Surgery, University of Michigan, 2Department of Internal Medicine, University of Michigan, 3Department of Otolaryngology, University of Michigan JoVE 50561 Immunology and Infection
黒色腫と扁平上癌幹細胞を用いた新規樹状細胞ワクチンの生成 Qiao Li1, Lin Lu1, Huimin Tao1, Carolyn Xue1, Seagal Teitz-Tennenbaum2, John H. Owen3, Jeffrey S Moyer3, Mark E.P. Prince3, Alfred E. Chang1, Max S. Wicha2 1Department of Surgery, University of Michigan, 2Department of Internal Medicine, University of Michigan, 3Department of Otolaryngology, University of Michigan JoVE 50561 Immunology and Infection
