Meenhard Herlyn

Publications

• Author Correction: Loss of Phd2 Cooperates with BRAF to Drive Melanomagenesis
  Nature Communications. 03, 2019  |   Pubmed ID: 30858377
• Genome-wide Prediction of Synthetic Rescue Mediators of Resistance to Targeted and Immunotherapy
  Molecular Systems Biology. Mar, 2019  |   Pubmed ID: 30858180
• BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2019  |   Pubmed ID: 30765391
• ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma
  Cancer Discovery. 03, 2019  |   Pubmed ID: 30563872
• Author Correction: PAK Signalling Drives Acquired Drug Resistance to MAPK Inhibitors in BRAF-mutant Melanomas
  Nature. 01, 2019  |   Pubmed ID: 30532003
• PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer
  Cancer Discovery. 02, 2019  |   Pubmed ID: 30442709
• Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility
  Cancer Discovery. 01, 2019  |   Pubmed ID: 30279173
• Loss of Phd2 Cooperates with BRAF to Drive Melanomagenesis
  Nature Communications. 12, 2018  |   Pubmed ID: 30575721
• A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
  Cell. Nov, 2018  |   Pubmed ID: 30388455
• Publisher Correction: Robust Prediction of Response to Immune Checkpoint Blockade Therapy in Metastatic Melanoma
  Nature Medicine. Dec, 2018  |   Pubmed ID: 30333558
• Frontiers in Pigment Cell and Melanoma Research
  Pigment Cell & Melanoma Research. 11, 2018  |   Pubmed ID: 30281213
• Targeting the Warburg Effect Via LDHA Inhibition Engages ATF4 Signaling for Cancer Cell Survival
  The EMBO Journal. Oct, 2018  |   Pubmed ID: 30209241
• Robust Prediction of Response to Immune Checkpoint Blockade Therapy in Metastatic Melanoma
  Nature Medicine. 10, 2018  |   Pubmed ID: 30127394
• Exosomal PD-L1 Contributes to Immunosuppression and is Associated with Anti-PD-1 Response
  Nature. 08, 2018  |   Pubmed ID: 30089911
• Tumor Innate Immunity Primed by Specific Interferon-stimulated Endogenous Retroviruses
  Nature Medicine. 08, 2018  |   Pubmed ID: 30038220
• Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2018  |   Pubmed ID: 29898988
• Endogenous Authentic OCT4A Proteins Directly Regulate FOS/AP-1 Transcription in Somatic Cancer Cells
  Cell Death & Disease. May, 2018  |   Pubmed ID: 29789579
• Co-targeting BET and MEK As Salvage Therapy for MAPK and Checkpoint Inhibitor-resistant Melanoma
  EMBO Molecular Medicine. 05, 2018  |   Pubmed ID: 29650805
• Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2018  |   Pubmed ID: 29563139
• Distinct Histone Modifications Denote Early Stress-induced Drug Tolerance in Cancer
  Oncotarget. Feb, 2018  |   Pubmed ID: 29492189
• Acetylsalicylic Acid Governs the Effect of Sorafenib in -Mutant Cancers
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 03, 2018  |   Pubmed ID: 29196297
• MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression
  The Journal of Investigative Dermatology. 01, 2018  |   Pubmed ID: 28927893
• Hypoxia-activated Prodrug Enhances Therapeutic Effect of Sunitinib in Melanoma
  Oncotarget. Dec, 2017  |   Pubmed ID: 29383148
• Melanoma Therapeutic Strategies That Select Against Resistance by Exploiting MYC-Driven Evolutionary Convergence
  Cell Reports. Dec, 2017  |   Pubmed ID: 29212027
• PAK Signalling Drives Acquired Drug Resistance to MAPK Inhibitors in BRAF-mutant Melanomas
  Nature. 10, 2017  |   Pubmed ID: 28953887
• Tumor-associated B-cells Induce Tumor Heterogeneity and Therapy Resistance
  Nature Communications. 09, 2017  |   Pubmed ID: 28928360
• A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles
  Cancer Discovery. 11, 2017  |   Pubmed ID: 28899863
• MEK'ing the Most of P53 Reactivation Therapy in Melanoma
  The Journal of Investigative Dermatology. Feb, 2012  |   Pubmed ID: 22241441
• Isolation and Characterization of Mouse and Human Esophageal Epithelial Cells in 3D Organotypic Culture
  Nature Protocols. 2012  |   Pubmed ID: 22240585
• Isolation and Cultivation of Dermal Stem Cells That Differentiate into Functional Epidermal Melanocytes
  Methods in Molecular Biology (Clifton, N.J.). 2012  |   Pubmed ID: 22057442
• Resistance to BRAF Inhibitors: Unraveling Mechanisms and Future Treatment Options
  Cancer Research. Dec, 2011  |   Pubmed ID: 22131348
• The Molecular Pathology of Cutaneous Melanoma
  Cancer Biomarkers : Section A of Disease Markers. 2011  |   Pubmed ID: 22112480
• Fibroblasts Contribute to Melanoma Tumor Growth and Drug Resistance
  Molecular Pharmaceutics. Dec, 2011  |   Pubmed ID: 22067046
• Direct Reprogramming of Melanocytes to Neural Crest Stem-like Cells by One Defined Factor
  Stem Cells (Dayton, Ohio). Nov, 2011  |   Pubmed ID: 21948558
• Organometallic Pyridylnaphthalimide Complexes As Protein Kinase Inhibitors
  Organometallics. Jul, 2011  |   Pubmed ID: 21918590
• Sorting Through the Many Opportunities for Melanoma Therapy
  Pigment Cell & Melanoma Research. Oct, 2011  |   Pubmed ID: 21899726
• A NOTCH3-mediated Squamous Cell Differentiation Program Limits Expansion of EMT-competent Cells That Express the ZEB Transcription Factors
  Cancer Research. Nov, 2011  |   Pubmed ID: 21890822
• From Cancer Stem Cells to Tumor Maintenance in Melanoma
  The Journal of Investigative Dermatology. Aug, 2011  |   Pubmed ID: 21654838
• Detecting and Targeting Mesenchymal-like Subpopulations Within Squamous Cell Carcinomas
  Cell Cycle (Georgetown, Tex.). Jun, 2011  |   Pubmed ID: 21558812
• Will Engineered T Cells Expressing CD20 ScFv Eradicate Melanoma?
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2011  |   Pubmed ID: 21455210
• Targeting BRAF in Advanced Melanoma: a First Step Toward Manageable Disease
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2011  |   Pubmed ID: 21447722
• Dermis-derived Stem Cells: a Source of Epidermal Melanocytes and Melanoma?
  Pigment Cell & Melanoma Research. Jun, 2011  |   Pubmed ID: 21410654
• Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K
  Cancer Cell. Dec, 2010  |   Pubmed ID: 21156289
• A Systems Biology Analysis of Metastatic Melanoma Using In-depth Three-dimensional Protein Profiling
  Proteomics. Dec, 2010  |   Pubmed ID: 21136598
• Taking the Guesswork out of Uveal Melanoma
  The New England Journal of Medicine. Dec, 2010  |   Pubmed ID: 21083377
• A Systems Biology Analysis of Metastatic Melanoma Using In-depth Three-dimensional Protein Profiling
  Proteomics. Oct, 2010  |   Pubmed ID: 21082759
• Boris Bastian
  Pigment Cell & Melanoma Research. Dec, 2010  |   Pubmed ID: 20973934
• PLX4032, a Potent Inhibitor of the B-Raf V600E Oncogene, Selectively Inhibits V600E-positive Melanomas
  Pigment Cell & Melanoma Research. Dec, 2010  |   Pubmed ID: 20973932
• Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth Via Activation of the PRMT5 Methyltransferase
  Cancer Cell. Oct, 2010  |   Pubmed ID: 20951943
• BRAF Inhibitor Unveils Its Potential Against Advanced Melanoma
  Cancer Cell. Oct, 2010  |   Pubmed ID: 20951940
• NOTCH1 and NOTCH3 Coordinate Esophageal Squamous Differentiation Through a CSL-dependent Transcriptional Network
  Gastroenterology. Dec, 2010  |   Pubmed ID: 20801121
• The Ups and Downs of Transcription Factors in Melanoma
  Journal of the National Cancer Institute. Aug, 2010  |   Pubmed ID: 20660367
• Fibroblast-secreted Hepatocyte Growth Factor Plays a Functional Role in Esophageal Squamous Cell Carcinoma Invasion
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010  |   Pubmed ID: 20534479
• Periostin, a Cell Adhesion Molecule, Facilitates Invasion in the Tumor Microenvironment and Annotates a Novel Tumor-invasive Signature in Esophageal Cancer
  Cancer Research. Jul, 2010  |   Pubmed ID: 20516120
• Insulin-like Growth Factor-binding Protein-3 Promotes Transforming Growth Factor-{beta}1-mediated Epithelial-to-mesenchymal Transition and Motility in Transformed Human Esophageal Cells
  Carcinogenesis. Aug, 2010  |   Pubmed ID: 20513670
• A Temporarily Distinct Subpopulation of Slow-cycling Melanoma Cells is Required for Continuous Tumor Growth
  Cell. May, 2010  |   Pubmed ID: 20478252
• Epidermal Growth Factor Receptor and Mutant P53 Expand an Esophageal Cellular Subpopulation Capable of Epithelial-to-mesenchymal Transition Through ZEB Transcription Factors
  Cancer Research. May, 2010  |   Pubmed ID: 20424117
• What is a Good Model for Melanoma?
  The Journal of Investigative Dermatology. Apr, 2010  |   Pubmed ID: 20231823
• Human Dermal Stem Cells Differentiate into Functional Epidermal Melanocytes
  Journal of Cell Science. Mar, 2010  |   Pubmed ID: 20159965
• Embryonic Stem Cells As a Model for Studying Melanocyte Development
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 19907984
• Distinct MHC Gene Expression Patterns During Progression of Melanoma
  Genes, Chromosomes & Cancer. Feb, 2010  |   Pubmed ID: 19862823
• Placental Gene Transfer: Transgene Screening in Mice for Trophic Effects on the Placenta
  American Journal of Obstetrics and Gynecology. Nov, 2009  |   Pubmed ID: 19716119
• Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes
  Cancer Research. Jul, 2009  |   Pubmed ID: 19549918
• The Role of BRAF Mutation and P53 Inactivation During Transformation of a Subpopulation of Primary Human Melanocytes
  The American Journal of Pathology. Jun, 2009  |   Pubmed ID: 19389934
• Driving in the Melanoma Landscape
  Experimental Dermatology. Jun, 2009  |   Pubmed ID: 19366372
• Defining Microenvironments Within Mouse Models That Enhance Tumor Aggressiveness
  Cancer Biology & Therapy. Feb, 2009  |   Pubmed ID: 19182538
• Cancer Stem Cells Are Everywhere
  Nature Medicine. Jan, 2009  |   Pubmed ID: 19129778
• Integrating Tumor-initiating Cells into the Paradigm for Melanoma Targeted Therapy
  International Journal of Cancer. Journal International Du Cancer. Mar, 2009  |   Pubmed ID: 19089923
• Cracking the System: Melanoma Complexity Demands New Therapeutic Approaches
  Pigment Cell & Melanoma Research. Feb, 2009  |   Pubmed ID: 19054340
• Matricellular Proteins Produced by Melanocytes and Melanomas: in Search for Functions
  Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. Dec, 2008  |   Pubmed ID: 19308688
• A Subpopulation of Mouse Esophageal Basal Cells Has Properties of Stem Cells with the Capacity for Self-renewal and Lineage Specification
  The Journal of Clinical Investigation. Dec, 2008  |   Pubmed ID: 19033657
• Cleavage of MCM2 Licensing Protein Fosters Senescence in Human Keratinocytes
  Cell Cycle (Georgetown, Tex.). Nov, 2008  |   Pubmed ID: 19001876
• Endothelin-3 Stimulates Survival of Goblet Cells in Organotypic Cultures of Fetal Human Colonic Epithelium
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2008  |   Pubmed ID: 18832450
• Increased Cyclin D1 Expression Can Mediate BRAF Inhibitor Resistance in BRAF V600E-mutated Melanomas
  Molecular Cancer Therapeutics. Sep, 2008  |   Pubmed ID: 18790768
• Bortezomib Induces Apoptosis in Esophageal Squamous Cell Carcinoma Cells Through Activation of the P38 Mitogen-activated Protein Kinase Pathway
  Molecular Cancer Therapeutics. Sep, 2008  |   Pubmed ID: 18790767
• Melanoma and the Tumor Microenvironment
  Current Oncology Reports. Sep, 2008  |   Pubmed ID: 18706274
• Identification of a Novel Subgroup of Melanomas with KIT/cyclin-dependent Kinase-4 Overexpression
  Cancer Research. Jul, 2008  |   Pubmed ID: 18632627
• Melanoma Stem Cells: the Dark Seed of Melanoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2008  |   Pubmed ID: 18539969
• Structure-based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity
  ACS Chemical Biology. May, 2008  |   Pubmed ID: 18484710
• Cytotoxicity of the Matrix Metalloproteinase-activated Anthrax Lethal Toxin is Dependent on Gelatinase Expression and B-RAF Status in Human Melanoma Cells
  Molecular Cancer Therapeutics. May, 2008  |   Pubmed ID: 18483309
• Unraveling the Mysteries of IGF-1 Signaling in Melanoma
  The Journal of Investigative Dermatology. Jun, 2008  |   Pubmed ID: 18478012
• The Essential Role of Fibroblasts in Esophageal Squamous Cell Carcinoma-induced Angiogenesis
  Gastroenterology. Jun, 2008  |   Pubmed ID: 18439605
• Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes
  Chemistry (Weinheim an Der Bergstrasse, Germany). 2008  |   Pubmed ID: 18425743
• Salmonella Typhimurium As a Novel RNA Interference Vector for Cancer Gene Therapy
  Cancer Biology & Therapy. Jan, 2008  |   Pubmed ID: 18347415
• Learning the ABCs of Melanoma-initiating Cells
  Cancer Cell. Mar, 2008  |   Pubmed ID: 18328422
• Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase with Potent Antimelanoma Activity
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008  |   Pubmed ID: 18287029
• The Differential Role of L1 in Ovarian Carcinoma and Normal Ovarian Surface Epithelium
  Cancer Research. Feb, 2008  |   Pubmed ID: 18281486
• Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma
  Cancer Research. Feb, 2008  |   Pubmed ID: 18245465
• Cancer Testis Antigens in Human Melanoma Stem Cells: Expression, Distribution, and Methylation Status
  Journal of Cellular Physiology. May, 2008  |   Pubmed ID: 18205182
• Microscale Solution IEF Combined with 2-D DIGE Substantially Enhances Analysis Depth of Complex Proteomes Such As Mammalian Cell and Tissue Extracts
  Electrophoresis. Feb, 2008  |   Pubmed ID: 18186533
• The Mitogen-activated Protein/extracellular Signal-regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression when Combined with Docetaxel
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2008  |   Pubmed ID: 18172275
• Permissive Environment in Postnatal Wounds Induced by Adenoviral-mediated Overexpression of the Anti-inflammatory Cytokine Interleukin-10 Prevents Scar Formation
  Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Jan-Feb, 2008  |   Pubmed ID: 18086289
• Roadmap for New Opportunities in Melanoma Research
  Seminars in Oncology. Dec, 2007  |   Pubmed ID: 18083380
• The Functional Interplay Between EGFR Overexpression, HTERT Activation, and P53 Mutation in Esophageal Epithelial Cells with Activation of Stromal Fibroblasts Induces Tumor Development, Invasion, and Differentiation
  Genes & Development. Nov, 2007  |   Pubmed ID: 17974918
• The Many Faces of Notch Signaling in Skin-derived Cells
  Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Dec, 2007  |   Pubmed ID: 17935489
• Unraveling Mysteries of the Multifunctional Protein SPARC
  The Journal of Investigative Dermatology. Nov, 2007  |   Pubmed ID: 17934501
• Raf Inhibitor Stabilizes Receptor for the Type I Interferon but Inhibits Its Anti-proliferative Effects in Human Malignant Melanoma Cells
  Cancer Biology & Therapy. Sep, 2007  |   Pubmed ID: 17873516
• Old Disease, New Culprit: Tumor Stem Cells in Cancer
  Journal of Cellular Physiology. Dec, 2007  |   Pubmed ID: 17786956
• Association of Polymorphisms of FAS-1377, FAS-670, and FASL-844 Genes with Risk Factors for Cutaneous Malignant Melanoma
  Cancer Journal (Sudbury, Mass.). Jul-Aug, 2007  |   Pubmed ID: 17762755
• Expression of Integrin Alpha10 is Induced in Malignant Melanoma
  Cellular Oncology : the Official Journal of the International Society for Cellular Oncology. 2007  |   Pubmed ID: 17726260
• Application of a BRAF Pyrosequencing Assay for Mutation Detection and Copy Number Analysis in Malignant Melanoma
  The Journal of Molecular Diagnostics : JMD. Sep, 2007  |   Pubmed ID: 17690212
• Rewired ERK-JNK Signaling Pathways in Melanoma
  Cancer Cell. May, 2007  |   Pubmed ID: 17482134
• Mutant V600E BRAF Increases Hypoxia Inducible Factor-1alpha Expression in Melanoma
  Cancer Research. Apr, 2007  |   Pubmed ID: 17409425
• Farming Cells to Rebuild Skin and Melanoma
  Cancer Biology & Therapy. Mar, 2007  |   Pubmed ID: 17374983
• Profiles of Chemokine Receptors in Melanocytic Lesions: De Novo Expression of CXCR6 in Melanoma
  Human Pathology. May, 2007  |   Pubmed ID: 17306330
• High-throughput Oncogene Mutation Profiling in Human Cancer
  Nature Genetics. Mar, 2007  |   Pubmed ID: 17293865
• Dysregulation of Claudin-7 Leads to Loss of E-cadherin Expression and the Increased Invasion of Esophageal Squamous Cell Carcinoma Cells
  The American Journal of Pathology. Feb, 2007  |   Pubmed ID: 17255337
• An Organometallic Protein Kinase Inhibitor Pharmacologically Activates P53 and Induces Apoptosis in Human Melanoma Cells
  Cancer Research. Jan, 2007  |   Pubmed ID: 17210701
• Microenvironmental Influences in Melanoma Progression
  Journal of Cellular Biochemistry. Jul, 2007  |   Pubmed ID: 17171636
• Life Isn't Flat: Taking Cancer Biology to the Next Dimension
  In Vitro Cellular & Developmental Biology. Animal. Sep-Oct, 2006  |   Pubmed ID: 17163781
• Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic BRAF by the Kinase Inhibitor SB-590885
  Cancer Research. Dec, 2006  |   Pubmed ID: 17145850
• CCN3 Controls 3D Spatial Localization of Melanocytes in the Human Skin Through DDR1
  The Journal of Cell Biology. Nov, 2006  |   Pubmed ID: 17101694
• Coordinated Functions of E-cadherin and Transforming Growth Factor Beta Receptor II in Vitro and in Vivo
  Cancer Research. Oct, 2006  |   Pubmed ID: 17047049
• Differentiation of Normal Skin and Melanoma Using High Resolution Hyperspectral Imaging
  Cancer Biology & Therapy. Aug, 2006  |   Pubmed ID: 16931902
• Embryogenesis Meets Tumorigenesis
  Nature Medicine. Aug, 2006  |   Pubmed ID: 16892028
• Metastatic Potential of Melanomas Defined by Specific Gene Expression Profiles with No BRAF Signature
  Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Aug, 2006  |   Pubmed ID: 16827748
• A New Organotypic Model to Study Cell Interactions in the Intestinal Mucosa
  European Journal of Gastroenterology & Hepatology. Aug, 2006  |   Pubmed ID: 16825910
• Multiple Signaling Pathways Must Be Targeted to Overcome Drug Resistance in Cell Lines Derived from Melanoma Metastases
  Molecular Cancer Therapeutics. May, 2006  |   Pubmed ID: 16731745
• Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles
  The American Journal of Pathology. Jun, 2006  |   Pubmed ID: 16723703
• Cancer Interaction with the Bone Microenvironment: a Workshop of the National Institutes of Health Tumor Microenvironment Study Section
  The American Journal of Pathology. May, 2006  |   Pubmed ID: 16651608
• Notch1 Signaling Promotes Primary Melanoma Progression by Activating Mitogen-activated Protein Kinase/phosphatidylinositol 3-kinase-Akt Pathways and Up-regulating N-cadherin Expression
  Cancer Research. Apr, 2006  |   Pubmed ID: 16618740
• Defining the Conditions for the Generation of Melanocytes from Human Embryonic Stem Cells
  Stem Cells (Dayton, Ohio). Jul, 2006  |   Pubmed ID: 16574754
• Inhibition of Endothelial Cell Proliferation by Notch1 Signaling is Mediated by Repressing MAPK and PI3K/Akt Pathways and Requires MAML1
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2006  |   Pubmed ID: 16571776
• Expression of PKC Isoforms in Human Melanocytic Cells in Situ
  Journal of Dermatological Science. Feb, 2006  |   Pubmed ID: 16406501
• Molecular Targets in Melanoma: Strategies and Challenges for Diagnosis and Therapy
  International Journal of Cancer. Journal International Du Cancer. Feb, 2006  |   Pubmed ID: 16258898
• Targeting Intracellular Signaling Pathways As a Novel Strategy in Melanoma Therapeutics
  Annals of the New York Academy of Sciences. Nov, 2005  |   Pubmed ID: 16382039
• Normal Human Melanocyte Homeostasis As a Paradigm for Understanding Melanoma
  The Journal of Investigative Dermatology. Symposium Proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. Nov, 2005  |   Pubmed ID: 16358819
• Targeting the Stromal Fibroblasts: a Novel Approach to Melanoma Therapy
  Expert Review of Anticancer Therapy. Dec, 2005  |   Pubmed ID: 16336098
• Activation of Notch1 Signaling is Required for Beta-catenin-mediated Human Primary Melanoma Progression
  The Journal of Clinical Investigation. Nov, 2005  |   Pubmed ID: 16239965
• A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas
  Cancer Research. Oct, 2005  |   Pubmed ID: 16230395
• Selective Evolutionary Pressure from the Tissue Microenvironment Drives Tumor Progression
  Seminars in Cancer Biology. Dec, 2005  |   Pubmed ID: 16043361
• Information Sharing and Collateral Damage
  Trends in Molecular Medicine. Aug, 2005  |   Pubmed ID: 16002338
• Bone Morphogenetic Proteins in Melanoma: Angel or Devil?
  Cancer Metastasis Reviews. Jun, 2005  |   Pubmed ID: 15986135
• Metastatic Melanoma Cells. Introduction
  Cancer Metastasis Reviews. Jun, 2005  |   Pubmed ID: 15986131
• The RAS/RAF/MEK/ERK and PI3K/AKT Signaling Pathways Present Molecular Targets for the Effective Treatment of Advanced Melanoma
  Frontiers in Bioscience : a Journal and Virtual Library. 2005  |   Pubmed ID: 15970553
• Adhesion, Migration and Communication in Melanocytes and Melanoma
  Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Jun, 2005  |   Pubmed ID: 15892711
• Up-regulated Expression of Zonula Occludens Protein-1 in Human Melanoma Associates with N-cadherin and Contributes to Invasion and Adhesion
  The American Journal of Pathology. May, 2005  |   Pubmed ID: 15855653
• The Prevalence of Interferon-alpha Transcription Defects in Malignant Melanoma
  Melanoma Research. Apr, 2005  |   Pubmed ID: 15846141
• CXC Chemokine Ligand 12 (stromal Cell-derived Factor 1 Alpha) and CXCR4-dependent Migration of CTLs Toward Melanoma Cells in Organotypic Culture
  Journal of Immunology (Baltimore, Md. : 1950). May, 2005  |   Pubmed ID: 15843590
• Activation of the DNA Damage Checkpoint and Genomic Instability in Human Precancerous Lesions
  Nature. Apr, 2005  |   Pubmed ID: 15829965
• Functional Erythropoietin Autocrine Loop in Melanoma
  The American Journal of Pathology. Mar, 2005  |   Pubmed ID: 15743794
• Gene Expression Profiling of Melanoma Cells - Searching the Haystack
  Journal of Translational Medicine. Jan, 2005  |   Pubmed ID: 15649323
• Cultivation of Normal Human Epidermal Melanocytes in the Absence of Phorbol Esters
  Methods in Molecular Medicine. 2005  |   Pubmed ID: 15492362
• Clinical Protocol. Phase I Trial to Evaluate the Safety of H5.020CMV.PDGF-b and Limb Compression Bandage for the Treatment of Venous Leg Ulcer: Trial A
  Human Gene Therapy. Oct, 2004  |   Pubmed ID: 15585116
• Adenoviral Mediated Gene Transfer of PDGF-B Enhances Wound Healing in Type I and Type II Diabetic Wounds
  Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Sep-Oct, 2004  |   Pubmed ID: 15453831
• Loitering with Intent: New Evidence for the Role of BRAF Mutations in the Proliferation of Melanocytic Lesions
  The Journal of Investigative Dermatology. Oct, 2004  |   Pubmed ID: 15373800
• The Role of Altered Cell-cell Communication in Melanoma Progression
  Journal of Molecular Histology. Mar, 2004  |   Pubmed ID: 15339050
• Rapid Apoptosis in the Pulmonary Vasculature Distinguishes Non-metastatic from Metastatic Melanoma Cells
  Cancer Letters. Sep, 2004  |   Pubmed ID: 15327836
• Akt/protein Kinase B Signaling Inhibitor-2, a Selective Small Molecule Inhibitor of Akt Signaling with Antitumor Activity in Cancer Cells Overexpressing Akt
  Cancer Research. Jul, 2004  |   Pubmed ID: 15231645
• Cyclin D1 is Essential for Neoplastic Transformation Induced by Both E6/E7 and E6/E7/ErbB-2 Cooperation in Normal Cells
  Oncogene. Jul, 2004  |   Pubmed ID: 15229656
• Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells
  The Journal of Biological Chemistry. Sep, 2004  |   Pubmed ID: 15226295
• Reversal of Melanocytic Malignancy by Keratinocytes is an E-cadherin-mediated Process Overriding Beta-catenin Signaling
  Experimental Cell Research. Jul, 2004  |   Pubmed ID: 15194432
• Truncation of Activated Leukocyte Cell Adhesion Molecule: a Gateway to Melanoma Metastasis
  The Journal of Investigative Dermatology. May, 2004  |   Pubmed ID: 15140234
• Recent Advances in Melanoma Biology
  The Oncologist. 2004  |   Pubmed ID: 15047922
• Induction of Melanoma Phenotypes in Human Skin by Growth Factors and Ultraviolet B
  Cancer Research. Feb, 2004  |   Pubmed ID: 14871803
• [Melanoma-stroma Interactions and Melanoma Progression]
  Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Oct, 2003  |   Pubmed ID: 16281812
• Human Melanoblasts in Culture: Expression of BRN2 and Synergistic Regulation by Fibroblast Growth Factor-2, Stem Cell Factor, and Endothelin-3
  The Journal of Investigative Dermatology. Nov, 2003  |   Pubmed ID: 14708619
• First International Melanoma Research Congress
  Cancer Biology & Therapy. Nov-Dec, 2003  |   Pubmed ID: 14688485
• The Great Escape: Another Way for Melanoma to Leave Physiological Control?
  The Journal of Investigative Dermatology. Oct, 2003  |   Pubmed ID: 14632176
• Reciprocal Regulation of MelCAM and AKT in Human Melanoma
  Oncogene. Oct, 2003  |   Pubmed ID: 14534536
• Axis of Evil: Molecular Mechanisms of Cancer Metastasis
  Oncogene. Sep, 2003  |   Pubmed ID: 14528277
• VEGF-A and AlphaVbeta3 Integrin Synergistically Rescue Angiogenesis Via N-Ras and PI3-K Signaling in Human Microvascular Endothelial Cells
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2003  |   Pubmed ID: 14519669
• Cisplatin Down-regulation of Cellular Fas-associated Death Domain-like Interleukin-1beta-converting Enzyme-like Inhibitory Proteins to Restore Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in Human Melanoma Cells
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2003  |   Pubmed ID: 14519653
• Suppression of BRAF(V599E) in Human Melanoma Abrogates Transformation
  Cancer Research. Sep, 2003  |   Pubmed ID: 14500344
• BRAF As a Potential Therapeutic Target in Melanoma and Other Malignancies
  Cancer Cell. Aug, 2003  |   Pubmed ID: 12957284
• Slit-Robo: Neuronal Guides Signal in Tumor Angiogenesis
  Cancer Cell. Jul, 2003  |   Pubmed ID: 12892705
• High Levels of CUG-initiated FGF-2 Expression Cause Chromatin Compaction, Decreased Cardiomyocyte Mitosis, and Cell Death
  Molecular and Cellular Biochemistry. Apr, 2003  |   Pubmed ID: 12841351
• Fibroblast Growth Factor-2 but Not Mel-CAM And/or Beta3 Integrin Promotes Progression of Melanocytes to Melanoma
  Experimental Dermatology. Jun, 2003  |   Pubmed ID: 12823444
• Tumors As Elusive Targets of T-cell-based Active Immunotherapy
  Trends in Immunology. Jun, 2003  |   Pubmed ID: 12810110
• Function and Regulation of Melanoma-stromal Fibroblast Interactions: when Seeds Meet Soil
  Oncogene. May, 2003  |   Pubmed ID: 12789292
• The Vascular Phenotype of Melanoma Metastasis
  Clinical & Experimental Metastasis. 2003  |   Pubmed ID: 12741681
• P16INK4A and Familial Melanoma
  Methods in Molecular Biology (Clifton, N.J.). 2003  |   Pubmed ID: 12710687
• Stimulation of Human Colonic Epithelial Cells by Leukemia Inhibitory Factor is Dependent on Collagen-embedded Fibroblasts in Organotypic Culture
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2003  |   Pubmed ID: 12692084
• Stroma Formation and Angiogenesis by Overexpression of Growth Factors, Cytokines, and Proteolytic Enzymes in Human Skin Grafted to SCID Mice
  The Journal of Investigative Dermatology. Apr, 2003  |   Pubmed ID: 12648235
• Constitutive Mitogen-activated Protein Kinase Activation in Melanoma is Mediated by Both BRAF Mutations and Autocrine Growth Factor Stimulation
  Cancer Research. Feb, 2003  |   Pubmed ID: 12591721
• Regulation of Notch1 and Dll4 by Vascular Endothelial Growth Factor in Arterial Endothelial Cells: Implications for Modulating Arteriogenesis and Angiogenesis
  Molecular and Cellular Biology. Jan, 2003  |   Pubmed ID: 12482957
• Differential Response of Primary and Metastatic Melanomas to Neutrophils Attracted by IL-8
  International Journal of Cancer. Journal International Du Cancer. Jan, 2003  |   Pubmed ID: 12471616
• Epidermal Growth Factor Receptor Mediates Increased Cell Proliferation, Migration, and Aggregation in Esophageal Keratinocytes in Vitro and in Vivo
  The Journal of Biological Chemistry. Jan, 2003  |   Pubmed ID: 12435727
• Melanoma Development and Progression: a Conspiracy Between Tumor and Host
  Differentiation; Research in Biological Diversity. Dec, 2002  |   Pubmed ID: 12492494
• BRAF and RAS Mutations in Human Lung Cancer and Melanoma
  Cancer Research. Dec, 2002  |   Pubmed ID: 12460918
• New Approaches to the Biology of Melanoma: a Workshop of the National Institutes of Health Pathology B Study Section
  The American Journal of Pathology. Nov, 2002  |   Pubmed ID: 12414540
• Cell-surface Proteolysis, Growth Factor Activation and Intercellular Communication in the Progression of Melanoma
  Critical Reviews in Oncology/hematology. Oct, 2002  |   Pubmed ID: 12398996
• The Role of E-cadherin in the Motility and Invasion of Implantation Site Intermediate Trophoblast
  Placenta. Nov, 2002  |   Pubmed ID: 12398810
• P53 Alone or in Combination with Antisense Cyclin D1 Induces Apoptosis and Reduces Tumor Size in Human Melanoma
  Cancer Gene Therapy. Oct, 2002  |   Pubmed ID: 12224020
• Prospective Molecular Profiling of Melanoma Metastases Suggests Classifiers of Immune Responsiveness
  Cancer Research. Jul, 2002  |   Pubmed ID: 12097256
• Fibroblast-dependent Differentiation of Human Microvascular Endothelial Cells into Capillary-like 3-dimensional Networks
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2002  |   Pubmed ID: 12060671
• Cyclin D1 is a Candidate Oncogene in Cutaneous Melanoma
  Cancer Research. Jun, 2002  |   Pubmed ID: 12036934
• Adenovirus-mediated Ex Vivo Gene Transfer of Human Vascular Endothelial Growth Factor in a Rabbit Laryngotracheal Reconstruction Model
  The Annals of Otology, Rhinology, and Laryngology. Apr, 2002  |   Pubmed ID: 11991579
• Melanoma-stroma Interactions: Structural and Functional Aspects
  The Lancet Oncology. Jan, 2002  |   Pubmed ID: 11905603
• Insulin-like Growth Factor-I-induced Migration of Melanoma Cells is Mediated by Interleukin-8 Induction
  Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research. Feb, 2002  |   Pubmed ID: 11864912
• Osteonectin/SPARC Induction by Ectopic Beta(3) Integrin in Human Radial Growth Phase Primary Melanoma Cells
  Cancer Research. Jan, 2002  |   Pubmed ID: 11782382
• Photocarcinogenesis in Human Adult Skin Grafts
  Carcinogenesis. Jan, 2002  |   Pubmed ID: 11756239
• Mechanism for Elimination of a Tumor Suppressor: Aberrant Splicing of a Brain-specific Exon Causes Loss of Function of Bin1 in Melanoma
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 1999  |   Pubmed ID: 10449755
• Induction of P21(WAF1/CIP1) and Inhibition of Cdk2 Mediated by the Tumor Suppressor P16(INK4a)
  Molecular and Cellular Biology. May, 1999  |   Pubmed ID: 10207115
• Adenoviral Gene Transfer of Beta3 Integrin Subunit Induces Conversion from Radial to Vertical Growth Phase in Primary Human Melanoma
  The American Journal of Pathology. Nov, 1998  |   Pubmed ID: 9811334