Melanie P. Matheu University of California San Francisco Diabetes Center University of California, San Francisco Biography Publications Institution JoVE Articles Melanie P. Matheu Dr. Melanie Matheu is the founder of Prellis Biologics. Dr. Matheu studied immunology for 15 years and authored numerous peer-reviewed publications and a book chapter detailing methods and approaches for high-resolution imaging in tissues before starting Prellis Biologics in October 2016. She was inspired to find a way to reverse-engineer laser-based imaging systems into a printer when she realized that the final roadblock in engineering human tissue and organs for transplant was a simple and well-defined engineering problem: how can microvasculature be printed fast enough to build human tissues? Prellis Biologics' technology solves this problem by partially decoupling printing speed from resolution with a novel patent-pending laser based projection system. Publications Immunoimaging: Studying Immune System Dynamics Using Two-photon Microscopy Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285279 In Vivo Lymph Node Imaging Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285268 In Situ Lymph Node Imaging Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285267 Induction of an Immune Response for Imaging Antigen-presenting Cell/T-cell Interactions Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285266 General Approach to Adoptive Transfer and Cell Labeling for Immunoimaging Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285265 Imaging of Effector Memory T Cells During a Delayed-type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block Immunity. Oct, 2008 | Pubmed ID: 18835197 Class IA Phosphoinositide 3-kinase Modulates Basal Lymphocyte Motility in the Lymph Node Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17675487 Enhancement of Capillary Leakage and Restoration of Lymphocyte Egress by a Chiral S1P1 Antagonist in Vivo Nature Chemical Biology. Aug, 2006 | Pubmed ID: 16829954 Sphingosine 1-phosphate Type 1 Receptor Agonism Inhibits Transendothelial Migration of Medullary T Cells to Lymphatic Sinuses Nature Immunology. Dec, 2005 | Pubmed ID: 16273098 Zwei-Photonen-Imaging von Zelluläre Dynamik in der Maus Spinal Cord Jason G. Weinger1, Milton L. Greenberg2, Melanie P. Matheu4, Ian Parker3, Craig M. Walsh1, Thomas E. Lane5, Michael D. Cahalan2 1Molecular Biology and Biochemistry, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine, 3Neurobiology and Behavior, University of California, Irvine, 4University of California San Francisco Diabetes Center, University of California, San Francisco, 5Pathology, University of Utah JoVE 52580 Neuroscience Imaging Effektor-Memory-T-Zellen im Ohr nach Induktion der Adoptive DTH Melanie P. Matheu1, Christine Beeton1, Ian Parker2, K. George Chandy1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behavior, University of California, Irvine (UCI) JoVE 907 Biology Isolierung von CD4 + T-Zellen aus Maus-Lymphknoten mit Miltenyi MACS Purification Melanie P. Matheu1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 409 Biology Dissection und 2-Photonen-Imaging der peripheren Lymphknoten in Mäusen Melanie P. Matheu1, Ian Parker2, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behaviour, University of California, Irvine (UCI) JoVE 265 Biology
Zwei-Photonen-Imaging von Zelluläre Dynamik in der Maus Spinal Cord Jason G. Weinger1, Milton L. Greenberg2, Melanie P. Matheu4, Ian Parker3, Craig M. Walsh1, Thomas E. Lane5, Michael D. Cahalan2 1Molecular Biology and Biochemistry, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine, 3Neurobiology and Behavior, University of California, Irvine, 4University of California San Francisco Diabetes Center, University of California, San Francisco, 5Pathology, University of Utah JoVE 52580 Neuroscience
Imaging Effektor-Memory-T-Zellen im Ohr nach Induktion der Adoptive DTH Melanie P. Matheu1, Christine Beeton1, Ian Parker2, K. George Chandy1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behavior, University of California, Irvine (UCI) JoVE 907 Biology
Isolierung von CD4 + T-Zellen aus Maus-Lymphknoten mit Miltenyi MACS Purification Melanie P. Matheu1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 409 Biology
Dissection und 2-Photonen-Imaging der peripheren Lymphknoten in Mäusen Melanie P. Matheu1, Ian Parker2, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behaviour, University of California, Irvine (UCI) JoVE 265 Biology
