Melody A. Swartz

Publications

• Introduction to the Special Issue on Lymphangiogenesis in Inflammation
  Angiogenesis. Apr, 2014  |   Pubmed ID: 24671660
• Emerging Roles of Lymphatic Endothelium in Regulating Adaptive Immunity
  The Journal of Clinical Investigation. Mar, 2014  |   Pubmed ID: 24590280
• Growth Factors Engineered for Super-affinity to the Extracellular Matrix Enhance Tissue Healing
  Science (New York, N.Y.). Feb, 2014  |   Pubmed ID: 24558160
• Targeting the Tumor-draining Lymph Node with Adjuvanted Nanoparticles Reshapes the Anti-tumor Immune Response
  Biomaterials. Jan, 2014  |   Pubmed ID: 24144906
• Optimization and Regeneration Kinetics of Lymphatic-specific Photodynamic Therapy in the Mouse Dermis
  Angiogenesis. Apr, 2014  |   Pubmed ID: 23892627
• Nanoparticle Conjugation of CpG Enhances Adjuvancy for Cellular Immunity and Memory Recall at Low Dose
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013  |   Pubmed ID: 24248387
• Engineering Synthetic Vaccines Using Cues from Natural Immunity
  Nature Materials. Nov, 2013  |   Pubmed ID: 24150416
• VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy
  The American Journal of Pathology. Nov, 2013  |   Pubmed ID: 24036251
• Cooperative Roles of SDF-1α and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model
  PloS One. 2013  |   Pubmed ID: 23869217
• The Promotion of Endothelial Cell Attachment and Spreading Using FNIII10 Fused to VEGF-A165
  Biomaterials. Aug, 2013  |   Pubmed ID: 23683723
• Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice
  PloS One. 2013  |   Pubmed ID: 23626707
• Normal Dendritic Cell Mobilization to Lymph Nodes Under Conditions of Severe Lymphatic Hypoplasia
  Journal of Immunology (Baltimore, Md. : 1950). May, 2013  |   Pubmed ID: 23530147
• Lymphatic Vasculature Mediates Macrophage Reverse Cholesterol Transport in Mice
  The Journal of Clinical Investigation. Apr, 2013  |   Pubmed ID: 23524964
• Tunable T Cell Immunity Towards a Protein Antigen Using Polymersomes Vs. Solid-core Nanoparticles
  Biomaterials. Jun, 2013  |   Pubmed ID: 23478034
• Intravital Immunofluorescence for Visualizing the Microcirculatory and Immune Microenvironments in the Mouse Ear Dermis
  PloS One. 2013  |   Pubmed ID: 23451163
• Interstitial Flow in a 3D Microenvironment Increases Glioma Invasion by a CXCR4-dependent Mechanism
  Cancer Research. Mar, 2013  |   Pubmed ID: 23271726
• ADAM17 Silencing in Mouse Colon Carcinoma Cells: the Effect on Tumoricidal Cytokines and Angiogenesis
  PloS One. 2012  |   Pubmed ID: 23251384
• Nanoparticle Size Influences the Magnitude and Quality of Mucosal Immune Responses After Intranasal Immunization
  Vaccine. Dec, 2012  |   Pubmed ID: 23103199
• Engineering Approaches to Immunotherapy
  Science Translational Medicine. Aug, 2012  |   Pubmed ID: 22914624
• Impaired Humoral Immunity and Tolerance in K14-VEGFR-3-Ig Mice That Lack Dermal Lymphatic Drainage
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2012  |   Pubmed ID: 22844119
• VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-presentation of Tumor Antigen by Lymph Node Lymphatics
  Cell Reports. Mar, 2012  |   Pubmed ID: 22832193
• Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer
  Physiological Reviews. Jul, 2012  |   Pubmed ID: 22811424
• Polymer Micelles with Pyridyl Disulfide-coupled Antigen Travel Through Lymphatics and Show Enhanced Cellular Responses Following Immunization
  Acta Biomaterialia. Sep, 2012  |   Pubmed ID: 22698945
• Dendritic Cell Activation and T Cell Priming with Adjuvant- and Antigen-loaded Oxidation-sensitive Polymersomes
  Biomaterials. Sep, 2012  |   Pubmed ID: 22658634
• Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy
  Cancer Research. May, 2012  |   Pubmed ID: 22414581
• Lymphatic and Interstitial Flow in the Tumour Microenvironment: Linking Mechanobiology with Immunity
  Nature Reviews. Cancer. Mar, 2012  |   Pubmed ID: 22362216
• Migration Dynamics of Breast Cancer Cells in a Tunable 3D Interstitial Flow Chamber
  Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2012  |   Pubmed ID: 22143066
• Multiscale Modeling of Lymphatic Drainage from Tissues Using Homogenization Theory
  Journal of Biomechanics. Jan, 2012  |   Pubmed ID: 22036032
• Nanoparticle Conjugation of Antigen Enhances Cytotoxic T-cell Responses in Pulmonary Vaccination
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011  |   Pubmed ID: 21969597
• PEG-b-PPS-b-PEI Micelles and PEG-b-PPS/PEG-b-PPS-b-PEI Mixed Micelles As Non-viral Vectors for Plasmid DNA: Tumor Immunotoxicity in B16F10 Melanoma
  Biomaterials. Dec, 2011  |   Pubmed ID: 21924769
• Nano-sized Drug-loaded Micelles Deliver Payload to Lymph Node Immune Cells and Prolong Allograft Survival
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2011  |   Pubmed ID: 21864593
• Nanoparticle Conjugation and Pulmonary Delivery Enhance the Protective Efficacy of Ag85B and CpG Against Tuberculosis
  Vaccine. Sep, 2011  |   Pubmed ID: 21787826
• Dendritic Cell Chemotaxis in 3D Under Defined Chemokine Gradients Reveals Differential Response to Ligands CCL21 and CCL19
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011  |   Pubmed ID: 21422278
• Regulation of Tumor Invasion by Interstitial Fluid Flow
  Physical Biology. Feb, 2011  |   Pubmed ID: 21301060
• Tumor Cell Invasion is Promoted by Interstitial Flow-induced Matrix Priming by Stromal Fibroblasts
  Cancer Research. Feb, 2011  |   Pubmed ID: 21245098
• Engineering Complement Activation on Polypropylene Sulfide Vaccine Nanoparticles
  Biomaterials. Mar, 2011  |   Pubmed ID: 21183216
• PPS Nanoparticles As Versatile Delivery System to Induce Systemic and Broad Mucosal Immunity After Intranasal Administration
  Vaccine. Jan, 2011  |   Pubmed ID: 21094269
• Antigen Delivery to Dendritic Cells by Poly(propylene Sulfide) Nanoparticles with Disulfide Conjugated Peptides: Cross-presentation and T Cell Activation
  Vaccine. Nov, 2010  |   Pubmed ID: 20934457
• Role of Lymphatic Vessels in Tumor Immunity: Passive Conduits or Active Participants?
  Journal of Mammary Gland Biology and Neoplasia. Sep, 2010  |   Pubmed ID: 20835756
• Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21
  Science (New York, N.Y.). May, 2010  |   Pubmed ID: 20339029
• Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium
  Circulation Research. Mar, 2010  |   Pubmed ID: 20133901
• Dermal Collagen and Lipid Deposition Correlate with Tissue Swelling and Hydraulic Conductivity in Murine Primary Lymphedema
  The American Journal of Pathology. Mar, 2010  |   Pubmed ID: 20110415
• Cells in 3D Matrices Under Interstitial Flow: Effects of Extracellular Matrix Alignment on Cell Shear Stress and Drag Forces
  Journal of Biomechanics. Mar, 2010  |   Pubmed ID: 20006339
• A Multichamber Fluidic Device for 3D Cultures Under Interstitial Flow with Live Imaging: Development, Characterization, and Applications
  Biotechnology and Bioengineering. Apr, 2010  |   Pubmed ID: 19953672
• Materials Engineering for Immunomodulation
  Nature. Nov, 2009  |   Pubmed ID: 19940915
• Fluid Flow Regulates Stromal Cell Organization and CCL21 Expression in a Tissue-engineered Lymph Node Microenvironment
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2009  |   Pubmed ID: 19734211
• Hypercholesterolemic Mice Exhibit Lymphatic Vessel Dysfunction and Degeneration
  The American Journal of Pathology. Sep, 2009  |   Pubmed ID: 19679879
• A Tissue-engineered Model of the Intestinal Lacteal for Evaluating Lipid Transport by Lymphatics
  Biotechnology and Bioengineering. Aug, 2009  |   Pubmed ID: 19396808
• An Agarose-based Microfluidic Platform with a Gradient Buffer for 3D Chemotaxis Studies
  Biomedical Microdevices. Aug, 2009  |   Pubmed ID: 19343497
• In Vitro Models of Inhalation Toxicity and Disease. The Report of a FRAME Workshop
  Alternatives to Laboratory Animals : ATLA. Feb, 2009  |   Pubmed ID: 19292579
• 3D Collagen Cultures Under Well-defined Dynamic Strain: a Novel Strain Device with a Porous Elastomeric Support
  Biotechnology and Bioengineering. May, 2009  |   Pubmed ID: 19148875
• Vascular Endothelial Growth Factor-C and C-C Chemokine Receptor 7 in Tumor Cell-lymphatic Cross-talk Promote Invasive Phenotype
  Cancer Research. Jan, 2009  |   Pubmed ID: 19118020
• Lymphatic Drainage Function and Its Immunological Implications: from Dendritic Cell Homing to Vaccine Design
  Seminars in Immunology. Apr, 2008  |   Pubmed ID: 18201895
• Effects of Dynamic Compression on Lentiviral Transduction in an in Vitro Airway Wall Model
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2008  |   Pubmed ID: 18024723
• Exploiting Lymphatic Transport and Complement Activation in Nanoparticle Vaccines
  Nature Biotechnology. Oct, 2007  |   Pubmed ID: 17873867
• Autologous Chemotaxis As a Mechanism of Tumor Cell Homing to Lymphatics Via Interstitial Flow and Autocrine CCR7 Signaling
  Cancer Cell. Jun, 2007  |   Pubmed ID: 17560334
• An Ultra-thin PDMS Membrane As a Bio/micro-nano Interface: Fabrication and Characterization
  Biomedical Microdevices. Aug, 2007  |   Pubmed ID: 17516172
• Interstitial Flow and Its Effects in Soft Tissues
  Annual Review of Biomedical Engineering. 2007  |   Pubmed ID: 17459001
• Bond-detach Lithography: a Method for Micro/nanolithography by Precision PDMS Patterning
  Small (Weinheim an Der Bergstrasse, Germany). Jan, 2007  |   Pubmed ID: 17294484
• Cooperative and Redundant Roles of VEGFR-2 and VEGFR-3 Signaling in Adult Lymphangiogenesis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2007  |   Pubmed ID: 17210781
• Regulation of Lymphatic Capillary Regeneration by Interstitial Flow in Skin
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2007  |   Pubmed ID: 17189348
• A Driving Force for Change: Interstitial Flow As a Morphoregulator
  Trends in Cell Biology. Jan, 2007  |   Pubmed ID: 17141502
• Engineered Blood and Lymphatic Capillaries in 3-D VEGF-fibrin-collagen Matrices with Interstitial Flow
  Biotechnology and Bioengineering. Jan, 2007  |   Pubmed ID: 17133613
• Effects of Extracellular Fiber Architecture on Cell Membrane Shear Stress in a 3D Fibrous Matrix
  Journal of Biomechanics. 2007  |   Pubmed ID: 16987520
• Physiological 3D Tissue Model of the Airway Wall and Mucosa
  Nature Protocols. 2006  |   Pubmed ID: 17406256
• Targeting Dendritic Cells with Biomaterials: Developing the Next Generation of Vaccines
  Trends in Immunology. Dec, 2006  |   Pubmed ID: 17049307
• Secondary Lymphedema in the Mouse Tail: Lymphatic Hyperplasia, VEGF-C Upregulation, and the Protective Role of MMP-9
  Microvascular Research. Nov, 2006  |   Pubmed ID: 16876204
• A Sensitive in Vivo Model for Quantifying Interstitial Convective Transport of Injected Macromolecules and Nanoparticles
  Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2006  |   Pubmed ID: 16763103
• Characterization of Lymphangiogenesis in a Model of Adult Skin Regeneration
  American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2006  |   Pubmed ID: 16648194
• Autologous Morphogen Gradients by Subtle Interstitial Flow and Matrix Interactions
  Biophysical Journal. Jul, 2006  |   Pubmed ID: 16603487
• Extracellular Matrix Remodeling by Dynamic Strain in a Three-dimensional Tissue-engineered Human Airway Wall Model
  American Journal of Respiratory Cell and Molecular Biology. Sep, 2006  |   Pubmed ID: 16601241
• In Vivo Targeting of Dendritic Cells in Lymph Nodes with Poly(propylene Sulfide) Nanoparticles
  Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2006  |   Pubmed ID: 16529839
• Capturing Complex 3D Tissue Physiology in Vitro
  Nature Reviews. Molecular Cell Biology. Mar, 2006  |   Pubmed ID: 16496023
• Mechanisms of Interstitial Flow-induced Remodeling of Fibroblast-collagen Cultures
  Annals of Biomedical Engineering. Mar, 2006  |   Pubmed ID: 16482410
• Microarray Analysis of VEGF-C Responsive Genes in Human Lymphatic Endothelial Cells
  Lymphatic Research and Biology. 2005  |   Pubmed ID: 16379588
• Mechanobiology in the Third Dimension
  Annals of Biomedical Engineering. Nov, 2005  |   Pubmed ID: 16341917
• Synergy Between Interstitial Flow and VEGF Directs Capillary Morphogenesis in Vitro Through a Gradient Amplification Mechanism
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005  |   Pubmed ID: 16249343
• Interstitial Fluid Flow Induces Myofibroblast Differentiation and Collagen Alignment in Vitro
  Journal of Cell Science. Oct, 2005  |   Pubmed ID: 16188933
• Dendritic-cell Trafficking to Lymph Nodes Through Lymphatic Vessels
  Nature Reviews. Immunology. Aug, 2005  |   Pubmed ID: 16056255
• Overexpression of VEGF-C Causes Transient Lymphatic Hyperplasia but Not Increased Lymphangiogenesis in Regenerating Skin
  Circulation Research. Jun, 2005  |   Pubmed ID: 15890974
• Complete and Specific Inhibition of Adult Lymphatic Regeneration by a Novel VEGFR-3 Neutralizing Antibody
  Journal of the National Cancer Institute. Jan, 2005  |   Pubmed ID: 15632376
• Interstitial Flow Differentially Stimulates Blood and Lymphatic Endothelial Cell Morphogenesis in Vitro
  Microvascular Research. Nov, 2004  |   Pubmed ID: 15501245
• Signaling in Morphogenesis: Transport Cues in Morphogenesis
  Current Opinion in Biotechnology. Oct, 2003  |   Pubmed ID: 14580587
• An in Vitro Airway Wall Model of Remodeling
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2003  |   Pubmed ID: 12851213
• Interstitial Flow As a Guide for Lymphangiogenesis
  Circulation Research. Apr, 2003  |   Pubmed ID: 12623882
• Fibroblast Alignment Under Interstitial Fluid Flow Using a Novel 3-D Tissue Culture Model
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2003  |   Pubmed ID: 12531726
• The Role of Interstitial Stress in Lymphatic Function and Lymphangiogenesis
  Annals of the New York Academy of Sciences. Dec, 2002  |   Pubmed ID: 12543729
• Bronchial Epithelial Compression Regulates MAP Kinase Signaling and HB-EGF-like Growth Factor Expression
  American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2002  |   Pubmed ID: 11943653