Meredith Crane Molecular Microbiology and Immunology Brown University Biography Publications Institution JoVE Articles Meredith CraneInvestigator I am interested in understanding how innate immunity helps to heal wounds and fight pathogens. This has been the common theme throughout my research career, beginning as a graduate student studying the immune response to murine cytomegalovirus infection. I now focus on how the cellular acute wound healing response is diverted by comorbid conditions, with the ultimate goal of identifying areas of intervention to improve wound healing outcomes. Publications Pulmonary Influenza A Virus Infection Leads to Suppression of the Innate Immune Response to Dermal Injury PLoS Pathogens. 08, 2018 | Pubmed ID: 30138446 Surviving Deadly Lung Infections: Innate Host Tolerance Mechanisms in the Pulmonary System Frontiers in Immunology. Month, 2018 | Pubmed ID: 29988424 The Monocyte to Macrophage Transition in the Murine Sterile Wound PloS One. Month, 2014 | Pubmed ID: 24466192 Toll-like Receptor 4 Signaling Regulates the Acute Local Inflammatory Response to Injury and the Fibrosis/neovascularization of Sterile Wounds Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Jul-Aug, 2013 | Pubmed ID: 23758142 IL-10 Mediated Regulation of Liver Inflammation During Acute Murine Cytomegalovirus Infection PloS One. Month, 2012 | Pubmed ID: 22880122 UNC93B1 Mediates Innate Inflammation and Antiviral Defense in the Liver During Acute Murine Cytomegalovirus Infection PloS One. Month, 2012 | Pubmed ID: 22723955 Regulation of Inflammatory Monocyte/macrophage Recruitment from the Bone Marrow During Murine Cytomegalovirus Infection: Role for Type I Interferons in Localized Induction of CCR2 Ligands Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009 | Pubmed ID: 19620305 IFN-alphabeta-mediated Inflammatory Responses and Antiviral Defense in Liver is TLR9-independent but MyD88-dependent During Murine Cytomegalovirus Infection Journal of Immunology (Baltimore, Md. : 1950). Nov, 2007 | Pubmed ID: 17947693 Evaluación de la cicatrización aguda de heridas utilizando los modelos de esponja de alcohol de polivinilo subcutáneo dorsal y modelos de herida sin piel de cola excisional. Meredith J. Crane1, William L. Henry Jr1, Holly L. Tran1, Jorge E. Albina2, Amanda M. Jamieson1 1Department of Molecular Microbiology & Immunology, Brown University, 2Division of Surgical Research, Department of Surgery, Rhode Island Hospital and The Warren Alpert School of Medicine of Brown University JoVE 60653 Immunology and Infection
Evaluación de la cicatrización aguda de heridas utilizando los modelos de esponja de alcohol de polivinilo subcutáneo dorsal y modelos de herida sin piel de cola excisional. Meredith J. Crane1, William L. Henry Jr1, Holly L. Tran1, Jorge E. Albina2, Amanda M. Jamieson1 1Department of Molecular Microbiology & Immunology, Brown University, 2Division of Surgical Research, Department of Surgery, Rhode Island Hospital and The Warren Alpert School of Medicine of Brown University JoVE 60653 Immunology and Infection
