Michael R. Krout Department of Chemistry Bucknell University Biography Publications Institution JoVE Articles Michael R. KroutAssistant Professor Michael Krout is an Assistant Professor in the Department of Chemistry at Bucknell University in Lewisburg, Pennsylvania. He received a B.S. in Biochemistry from the Indiana University of Pennsylvania, and a Ph.D. from the California Institute of Technology.Dr. Krout’s training has focused on the development of efficient and selective organic transformations that enable the synthesis of complex molecules. As a graduate student in the lab of Brian Stoltz at Caltech, he studied various reaction technologies that were leveraged as key steps in the asymmetric synthesis of terpene natural products, including the palladium-catalyzed asymmetric alkylation of vinylogous esters in the preparation of all-carbon quaternary centers, a ring contraction method for the synthesis of versatile acylcyclopentenes, and a tandem Wolff/Cope rearrangement to access complex cyclooctenones. He then moved to David Gin’s lab at the Memorial Sloan-Kettering Cancer Center as an NIH postdoctoral fellow. Here he explored annulation methods en route to alkaloid and steroid natural products.Dr. Krout joined the faculty at Bucknell University in 2012 as a Visiting Assistant Professor, and was promoted to Assistant Professor in 2014. His research program encompasses the development and application of chemo- and stereoselective transformations for the synthesis of bile acids and other valuable organic molecules. Publications Access to Functionalized Quaternary Stereocenters Via the Copper-Catalyzed Conjugate Addition of Monoorganozinc Bromide Reagents Enabled by N, N-Dimethylacetamide The Journal of Organic Chemistry. Dec, 2018 | Pubmed ID: 30376627 Wolff/Cope Approach to the AB Ring of the Sesterterpenoid Variecolin The Journal of Organic Chemistry. Jul, 2018 | Pubmed ID: 29298482 Resolved P-metalated Nucleoside Phosphoramidites Inorganic Chemistry. Dec, 2014 | Pubmed ID: 25437274 Efficiënte synthese van all-Carbon quaternaire Centers via de geconjugeerde toevoeging van functionele Monoorganozinc bromiden Tyler J. Fulton1, Katherine M. Townsend2, Michael R. Krout2 1Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, California Institute of Technology, 2Department of Chemistry, Bucknell University JoVE 59775 Chemistry
Efficiënte synthese van all-Carbon quaternaire Centers via de geconjugeerde toevoeging van functionele Monoorganozinc bromiden Tyler J. Fulton1, Katherine M. Townsend2, Michael R. Krout2 1Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, California Institute of Technology, 2Department of Chemistry, Bucknell University JoVE 59775 Chemistry
