Michael B. Stout Aging and Metabolism Research Program Oklahoma Medical Research Foundation Biography Publications Institution JoVE Articles Michael B. Stout has not added a biography. If you are Michael B. Stout and would like to personalize this page please email our Author Liaison for assistance. Publications A Genetically Heterogeneous Rat Model with Divergent Mitochondrial Genomes The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2023 | Pubmed ID: 36762848 17α-estradiol, a Lifespan-extending Compound, Attenuates Liver Fibrosis by Modulating Collagen Turnover Rates in Male Mice American Journal of Physiology. Endocrinology and Metabolism. Feb, 2023 | Pubmed ID: 36516471 17α-estradiol Does Not Adversely Affect Sperm Parameters or Fertility in Male Mice: Implications for Reproduction-longevity Trade-offs GeroScience. Jun, 2022 | Pubmed ID: 35689785 Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex Molecular Neurobiology. Aug, 2022 | Pubmed ID: 35589920 Senolytic Treatment Reverses Obesity-mediated Senescent Cell Accumulation in the Ovary GeroScience. Jun, 2022 | Pubmed ID: 35460445 Obesity Promotes Lipid Accumulation in Mouse Cartilage-A Potential Role of Acetyl-CoA Carboxylase (ACC) Mediated Chondrocyte De Novo Lipogenesis Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Dec, 2022 | Pubmed ID: 35279877 Mild Calorie Restriction, but Not 17α-estradiol, Extends Ovarian Reserve and Fertility in Female Mice Experimental Gerontology. Mar, 2022 | Pubmed ID: 35032571 Litter Expansion Alters Metabolic Homeostasis in a Sex Specific Manner PloS One. 2021 | Pubmed ID: 34587168 Cellular Hallmarks of Aging Emerge in the Ovary Prior to Primordial Follicle Depletion Mechanisms of Ageing and Development. Mar, 2021 | Pubmed ID: 33383072 Health Benefits Attributed to 17α-estradiol, a Lifespan-extending Compound, Are Mediated Through Estrogen Receptor α ELife. Dec, 2020 | Pubmed ID: 33289482 Inducible Cell-specific Mouse Models for Paired Epigenetic and Transcriptomic Studies of Microglia and Astroglia Communications Biology. Nov, 2020 | Pubmed ID: 33214681 Short-term Calorie Restriction and 17α-Estradiol Administration Elicit Divergent Effects on Proteostatic Processes and Protein Content in Metabolically Active Tissues The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Apr, 2020 | Pubmed ID: 31074767 Identification of a Novel Senolytic Agent, Navitoclax, Targeting the Bcl-2 Family of Anti-apoptotic Factors Aging Cell. 06, 2016 | Pubmed ID: 26711051 The Achilles' Heel of Senescent Cells: from Transcriptome to Senolytic Drugs Aging Cell. Aug, 2015 | Pubmed ID: 25754370 Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome Sarah R. Ocañas*1,2,3, José V. V. Isola*1,3, Tatiana D. Saccon1, Kevin D. Pham2, Ana J. Chucair-Elliott2, Augusto Schneider4, Willard M. Freeman2,3, Michael B. Stout1,3 1Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 2Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, 3Oklahoma City Veterans Affairs Medical Center, 4Nutrition College, Federal University of Pelotas JoVE 64765 Biology
Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome Sarah R. Ocañas*1,2,3, José V. V. Isola*1,3, Tatiana D. Saccon1, Kevin D. Pham2, Ana J. Chucair-Elliott2, Augusto Schneider4, Willard M. Freeman2,3, Michael B. Stout1,3 1Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 2Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, 3Oklahoma City Veterans Affairs Medical Center, 4Nutrition College, Federal University of Pelotas JoVE 64765 Biology